A cell-based nitric oxide reporter assay useful for the identification and characterization of modulators of the nitric oxide/guanosine 3′,5′-cyclic monophosphate pathway

Analytical Biochemistry

Volumn 363, Issue 2, 2007, Pages 219-227

  Wunder, Frank ^a   Buehler, Guido ^a   Hüser, Jörg ^a   Mundt, Stefan ^a   Bechem, Martin ^a   Kalthof, Bernd ^a  

^a BAYER PHARMA AG   (Germany)

Author keywords

cGMP; CNG channel; eNOS; Nitric oxide; Soluble guanylyl cyclase

Indexed keywords

BIOSYNTHESIS; CELL SIGNALING; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; DRUG DELIVERY; DRUG PRODUCTS; NUCLEOTIDES; WELL STIMULATION;

CGMP; CNG CHANNEL; ENDOTHELIAL NITRIC-OXIDE SYNTHASE (ENOS); ENOS; G PROTEIN COUPLED RECEPTORS; GUANYLYL CYCLASE; HIGH THROUGHPUT SCREENING; SOLUBLE GUANYLYL CYCLASE (SGC);

NITRIC OXIDE;

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; ASCORBIC ACID; BRADYKININ; CALCIUM ION; CATION CHANNEL; CYCLIC GMP; CYCLIC NUCLEOTIDE GATED CATION CHANNEL CNGA2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; G PROTEIN COUPLED RECEPTOR AGONIST; GUANYLATE CYCLASE; N(G) METHYLARGININE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROTEIN DERIVATIVE; SEPIAPTERIN; STAUROSPORINE; UNCLASSIFIED DRUG; VANADIC ACID; WORTMANNIN;

ANIMAL CELL; ARTICLE; BIOASSAY; CALCIUM TRANSPORT; CELL ASSAY; COCULTURE; CONTROLLED STUDY; ENZYME REGULATION; FEMALE; HIGH THROUGHPUT SCREENING; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 33947276805     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2007.02.001     Document Type: Article

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