Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero

Regulatory Toxicology and Pharmacology

Volumn 30, Issue 2 II, 1999, Pages 156-166

  Ashby, John ^a   Tinwell, H ^a   Haseman, J ^b  

^a ASTRAZENECA   (United Kingdom)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; DIETHYLSTILBESTROL;

ANIMAL EXPERIMENT; ARTICLE; DOSE RESPONSE; GROWTH REGULATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE; SPERMATOGENESIS; TOXICITY TESTING;

ANIMALIA;

EID: 0032729758     PISSN: 02732300     EISSN: None     Source Type: Journal    
DOI: 10.1006/rtph.1999.1317     Document Type: Article

References (11)

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2. Ashby, J., Tinwell, H., Lefevre, P. A., Odum, J., Paton, D., Millward, S. W., Tittensor, S., and Brooks, A. N. (1997). Normal sexual development of rats exposed to butyl benzyl phthalate from conception to weaning. Regul. Toxicol. Pharmacol. 26, 102-118.
3. Blazak, W. F., Treinen, K. A., and Juniewicz, P. E. (1993). Application of testicular sperm head counts in the assessment of male reproductive toxicity. In Methods in Toxicology, Vol 3A, Male Reproductive Toxicology (R. E. Chapin and J. J. Heindel, Eds.), pp. 86-94, Academic Press, San Diego.
4. Cagen, S. Z., Waechter, J. M., Jr., Dimond, S. S., Breslin, W. J., Butala, J. H., Jekat, F. W., Joiner, R. L., Shiotsuka, R. N., Veenstra, G. E., and Harris, L. R. (1999). Normal reproductive organ development in CF-1 mice following prenatal exposure to Bisphenol A. Toxicol. Sci. 50, 36-44.
5. Morrison, V., Tinwell, H., and Ashby, J. (1995). Consideration of the liver of embryonic Lac Z transgenic mice as an analogue of the mouse coat colour spot test: Preliminary data and technical problems. Mutat. Res. 329, 107-112.
6. Nagel, S. C., vom Saal, F. S., Thayer, K. A., Dhar, M. G., Boechler, M., and Welshons, W. V. (1997). Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol. Environ. Health Perspect. 105, 70-76.
7. Odum, J., Lefevre, P. A., Tittensor, S., Paton, D., Harris, C. A., Beresford, N. A., Sumpter, J. P., and Ashby, J. (1997). The rodent uterotrophic assay: Critical protocol features, studies with nonylphenols, comparison with a yeast estrogenicity assay. Regul. Toxicol. Pharmacol. 26, 176-188.
8. Odum, J., Pyrah, I. T. G., Foster, J. R., Van Miller, J. P., Joiner, R. L., and Ashby, J. (1999). Comparative activities of p-nonylphenol and diethylstilbestrol in Noble rat mammary gland and uterotrophic assays. Regul. Toxicol. Pharmacol., in press.
9. Sheehan, D. (1999). Proceedings of the Toxicology Forum discussion, Toxicology Forum Meeting, Washington, April 12-13.
10. Thigpen, J. E., Setchel, K. D. R., Goelz, M. F., and Forsythe, D. B. (1999). The phytoestrogen content of rodent diets. Environ. Health Perspect. 107, A182-183.
11. vom Saal, F. S., Cooke, P. S., Buchanan, D. L., Palanza, P., Thayer, K., Nagel, S. C., Parmigiani, S., and Welshons, W. V. (1998). A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production and behavior. Toxicol. Indust. Health 14 (1/2), 239-260.