Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats

Toxicological Sciences

Volumn 68, Issue 1, 2002, Pages 121-146

  Tyl, R W ^a   Myers, C B ^a   Marr, M C ^a   Thomas, B F ^a   Keimowitz, A R ^a   Brine, D R ^a   Veselica, M M ^a   Fail, P A ^a   Chang, T Y ^a   Seely, J C ^b   Joiner, R L ^c   Butala, J H ^d   Dimond, S S ^c   Cagen, S Z ^e   Shiotsuka, R N ^f   Stropp, G D ^g   Waechter, J M ^h  

^a RTI INTERNATIONAL   (United States)

^b EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

^c GE PLASTICS   (United States)

^d Aristech Chemical Corporation   (United States)

^e Shell Chemical Co   (United States)

^f BAYER CORPORATION   (United States)

^g BAYER AG   (Germany)

^h DOW CHEMICAL COMPANY   (United States)

Author keywords

Bisphenol A; CAS No. 80 05 7; Dietary administration; OPPTS 837.3800 guidelines; Postnatal toxicity; Reproductive toxicity; Systemic toxicity

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ESTROGEN; PHENOL DERIVATIVE;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN WEIGHT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIETARY INTAKE; DOSE RESPONSE; EPIDIDYMIS; ESTRUS CYCLE; FEMALE; FERTILITY; HISTOPATHOLOGY; HYPOPHYSIS; KIDNEY DISEASE; KIDNEY MASS; LIVER DISEASE; LIVER WEIGHT; MALE; MATING; MAXIMUM TOLERATED DOSE; MORPHOLOGY; NONHUMAN; ORGAN WEIGHT; OVARY; OVARY FOLLICLE; PREGNANCY; RAT; REPRODUCTION; REPRODUCTIVE TOXICITY; SEX RATIO; SPERMATOGENESIS; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; SPLEEN WEIGHT; SURVIVAL; WEIGHT GAIN; WEIGHT REDUCTION; ANIMAL; BODY WEIGHT; DIET; DRUG EFFECT; DRUG SURVEILLANCE PROGRAM; LACTATION; ORAL DRUG ADMINISTRATION; ORGAN SIZE; PRENATAL EXPOSURE; SEXUAL MATURATION; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ANIMAL; BODY WEIGHT; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGENS, NON-STEROIDAL; FEMALE; LACTATION; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN WEIGHT; PHENOLS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCTION; SEX MATURATION; SUPPORT, NON-U.S. GOV'T; ANIMALS; ORGAN SIZE; SEXUAL MATURATION;

ANIMALIA;

EID: 0035996069     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/68.1.121     Document Type: Article

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