메뉴 건너뛰기




Volumn 22, Issue 7, 2011, Pages 665-672

Effects of long-term supplementation with omega-3 fatty acids on longitudinal changes in bone mass and microstructure in mice

Author keywords

Bone mineral density; Leptin; Long term; Microarchitecture; Omega 3; Strength

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; LEPTIN;

EID: 79958780847     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2010.05.006     Document Type: Article
Times cited : (40)

References (59)
  • 3
    • 0026438801 scopus 로고
    • The apparent incidence of hip fracture in Europe: a study of national register sources MEDOS Study Group
    • Ohnell O., Gullberg B., Allander E., Kanis J.A. The apparent incidence of hip fracture in Europe: a study of national register sources MEDOS Study Group. Osteoporos Int 1992, 2:298-302.
    • (1992) Osteoporos Int , vol.2 , pp. 298-302
    • Ohnell, O.1    Gullberg, B.2    Allander, E.3    Kanis, J.A.4
  • 7
    • 34548858174 scopus 로고    scopus 로고
    • Mediterranean diet and osteoporosis prevention
    • Puel C., Coxam V., Davicco M.J. Mediterranean diet and osteoporosis prevention. Med Sci 2007, 23:756-760.
    • (2007) Med Sci , vol.23 , pp. 756-760
    • Puel, C.1    Coxam, V.2    Davicco, M.J.3
  • 9
    • 67849129098 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids and cardiovascular diseases
    • Lavie C.J., Milani R.V., Mehra M.R., Ventura H.O. Omega-3 polyunsaturated fatty acids and cardiovascular diseases. J Am Coll Cardiol 2009, 54:585-594.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 585-594
    • Lavie, C.J.1    Milani, R.V.2    Mehra, M.R.3    Ventura, H.O.4
  • 10
    • 0026094489 scopus 로고
    • Omega-3 fatty acids in health and disease and in growth and development
    • Simopoulos A.P. Omega-3 fatty acids in health and disease and in growth and development. Am J Clin Nutr 1991, 54:438-463.
    • (1991) Am J Clin Nutr , vol.54 , pp. 438-463
    • Simopoulos, A.P.1
  • 12
    • 17844365292 scopus 로고    scopus 로고
    • Ratio of n-6 to n-3 fatty acids and bone mineral density in older adults: the Rancho Bernardo Study
    • Weiss L.A., Barrett-Connor E., von Mühlen D. Ratio of n-6 to n-3 fatty acids and bone mineral density in older adults: the Rancho Bernardo Study. Am J Clin Nutr 2005, 81:934-938.
    • (2005) Am J Clin Nutr , vol.81 , pp. 934-938
    • Weiss, L.A.1    Barrett-Connor, E.2    von Mühlen, D.3
  • 13
    • 35548993784 scopus 로고    scopus 로고
    • Long-chain polyunsaturated fatty acids and the regulation of bone metabolism
    • Poulsen R.C., Moughan P.J., Kruger M.C. Long-chain polyunsaturated fatty acids and the regulation of bone metabolism. Exp Biol Med (Maywood) 2007, 232:1275-1288.
    • (2007) Exp Biol Med (Maywood) , vol.232 , pp. 1275-1288
    • Poulsen, R.C.1    Moughan, P.J.2    Kruger, M.C.3
  • 14
    • 0037951860 scopus 로고    scopus 로고
    • Dietary n-3 fatty acids decrease osteoclastogenesis and loss of bone mass in ovariectomized mice
    • Sun D., Krishnan A., Zaman K., Lawrence R., Bhattacharya A., Fernandes G. Dietary n-3 fatty acids decrease osteoclastogenesis and loss of bone mass in ovariectomized mice. J Bone Miner Res 2003, 18:1206-1216.
    • (2003) J Bone Miner Res , vol.18 , pp. 1206-1216
    • Sun, D.1    Krishnan, A.2    Zaman, K.3    Lawrence, R.4    Bhattacharya, A.5    Fernandes, G.6
  • 16
    • 38049069892 scopus 로고    scopus 로고
    • Long chain polyunsaturated fatty acids alter membrane-bound RANK-L expression and osteoprotegerin secretion by MC3T3-E1 osteoblast-like cells
    • Poulsen R.C., Wolber F.M., Moughan P.J., Kruger M.C. Long chain polyunsaturated fatty acids alter membrane-bound RANK-L expression and osteoprotegerin secretion by MC3T3-E1 osteoblast-like cells. Prostaglandins Other Lipid Mediat 2008, 85:42-48.
    • (2008) Prostaglandins Other Lipid Mediat , vol.85 , pp. 42-48
    • Poulsen, R.C.1    Wolber, F.M.2    Moughan, P.J.3    Kruger, M.C.4
  • 17
    • 23944487019 scopus 로고    scopus 로고
    • Inhibition of osteoporosis in autoimmune disease prone MRL/Mpj-Fas(lpr) mice by N-3 fatty acids
    • Bhattacharya A., Rahman M., Banu J., Lawrence R.A., McGuff H.S., Garrett I.R., et al. Inhibition of osteoporosis in autoimmune disease prone MRL/Mpj-Fas(lpr) mice by N-3 fatty acids. J Am Coll Nutr 2005, 24:200-209.
    • (2005) J Am Coll Nutr , vol.24 , pp. 200-209
    • Bhattacharya, A.1    Rahman, M.2    Banu, J.3    Lawrence, R.A.4    McGuff, H.S.5    Garrett, I.R.6
  • 18
    • 33845935766 scopus 로고    scopus 로고
    • Effects of arachidonic acid, docosahexaenoic acid and prostaglandin E(2) on cell proliferation and morphology of MG-63 and MC3T3-E1 osteoblast-like cells
    • Coetzee M., Haag M., Joubert A.M., Kruger M.C. Effects of arachidonic acid, docosahexaenoic acid and prostaglandin E(2) on cell proliferation and morphology of MG-63 and MC3T3-E1 osteoblast-like cells. Prostaglandins Leukot Essent Fatty Acids 2007, 76:35-45.
    • (2007) Prostaglandins Leukot Essent Fatty Acids , vol.76 , pp. 35-45
    • Coetzee, M.1    Haag, M.2    Joubert, A.M.3    Kruger, M.C.4
  • 19
    • 0030764696 scopus 로고    scopus 로고
    • Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism
    • Frøyland L., Madsen L., Vaagenes H., Totland G.K., Auwerx J., Kryvi H., et al. Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism. J Lipid Res 1997, 38:1851-1858.
    • (1997) J Lipid Res , vol.38 , pp. 1851-1858
    • Frøyland, L.1    Madsen, L.2    Vaagenes, H.3    Totland, G.K.4    Auwerx, J.5    Kryvi, H.6
  • 20
    • 31544457103 scopus 로고    scopus 로고
    • Mechanisms of disease: is osteoporosis the obesity of bone?
    • Rosen C.J., Bouxsein M.L. Mechanisms of disease: is osteoporosis the obesity of bone?. Nat Clin Pract Rheumatol 2006, 2:35-43.
    • (2006) Nat Clin Pract Rheumatol , vol.2 , pp. 35-43
    • Rosen, C.J.1    Bouxsein, M.L.2
  • 21
    • 36849030362 scopus 로고    scopus 로고
    • Docosahexaenoic acid is more potent inhibitor of osteoclast differentiation in RAW 264.7 cells than eicosapentaenoic acid
    • Rahman M.M., Bhattacharya A., Fernandes G. Docosahexaenoic acid is more potent inhibitor of osteoclast differentiation in RAW 264.7 cells than eicosapentaenoic acid. J Cell Physiol 2008, 214:201-209.
    • (2008) J Cell Physiol , vol.214 , pp. 201-209
    • Rahman, M.M.1    Bhattacharya, A.2    Fernandes, G.3
  • 22
    • 0031455061 scopus 로고    scopus 로고
    • Calcium metabolism, osteoporosis and essential fatty acids: a review
    • Kruger M.C., Horrobin D.F. Calcium metabolism, osteoporosis and essential fatty acids: a review. Prog Lipid Res 1997, 36:131-151.
    • (1997) Prog Lipid Res , vol.36 , pp. 131-151
    • Kruger, M.C.1    Horrobin, D.F.2
  • 24
    • 25444466176 scopus 로고    scopus 로고
    • Is docosahexaenoic acid more effective than eicosapentaenoic acid for increasing calcium bioavailability?
    • Kruger M.C., Schollum L.M. Is docosahexaenoic acid more effective than eicosapentaenoic acid for increasing calcium bioavailability?. Prostaglandins Leukot Essent Fatty Acids 2005, 73:327-334.
    • (2005) Prostaglandins Leukot Essent Fatty Acids , vol.73 , pp. 327-334
    • Kruger, M.C.1    Schollum, L.M.2
  • 25
    • 37549004413 scopus 로고    scopus 로고
    • Specific effects of gamma-linolenic, eicosapentaenoic, and docosahexaenoic ethyl esters on bone post-ovariectomy in rats
    • Poulsen R.C., Firth E.C., Rogers C.W., Moughan P.J., Kruger M.C. Specific effects of gamma-linolenic, eicosapentaenoic, and docosahexaenoic ethyl esters on bone post-ovariectomy in rats. Calcif Tissue Int 2007, 81:459-471.
    • (2007) Calcif Tissue Int , vol.81 , pp. 459-471
    • Poulsen, R.C.1    Firth, E.C.2    Rogers, C.W.3    Moughan, P.J.4    Kruger, M.C.5
  • 26
    • 0029880186 scopus 로고    scopus 로고
    • Genetic variability in adult bone density among inbred strains of mice
    • Beamer W.G., Donahue L.R., Rosen C.J., Baylink D.J. Genetic variability in adult bone density among inbred strains of mice. Bone 1996, 18:397-403.
    • (1996) Bone , vol.18 , pp. 397-403
    • Beamer, W.G.1    Donahue, L.R.2    Rosen, C.J.3    Baylink, D.J.4
  • 27
    • 34548080918 scopus 로고    scopus 로고
    • Age-related changes in trabecular architecture differ in female and male C57BL/6J mice
    • Glatt V., Canalis E., Stadmeyer L., Bouxsein M.L. Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Miner Res 2007, 22:1197-1207.
    • (2007) J Bone Miner Res , vol.22 , pp. 1197-1207
    • Glatt, V.1    Canalis, E.2    Stadmeyer, L.3    Bouxsein, M.L.4
  • 28
    • 27944449749 scopus 로고    scopus 로고
    • In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography
    • Boutroy S., Bouxsein M.L., Munoz F., Delmas P.D. In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Metab 2005, 90:6508-6515.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 6508-6515
    • Boutroy, S.1    Bouxsein, M.L.2    Munoz, F.3    Delmas, P.D.4
  • 29
    • 0041762493 scopus 로고    scopus 로고
    • Bone development and age-related bone loss in male C57BL/6J mice
    • Ferguson V.L., Ayers R.A., Bateman T.A., Simske S.J. Bone development and age-related bone loss in male C57BL/6J mice. Bone 2003, 33:387-398.
    • (2003) Bone , vol.33 , pp. 387-398
    • Ferguson, V.L.1    Ayers, R.A.2    Bateman, T.A.3    Simske, S.J.4
  • 30
    • 2442572428 scopus 로고    scopus 로고
    • Growth of C57BL/6 mice and the material and mechanical properties of cortical bone from the tibia
    • Somerville J.M., Aspden R.M., Armour K.E., Armour K.J., Reid D.M. Growth of C57BL/6 mice and the material and mechanical properties of cortical bone from the tibia. Calcif Tissue Int 2004, 74:469-475.
    • (2004) Calcif Tissue Int , vol.74 , pp. 469-475
    • Somerville, J.M.1    Aspden, R.M.2    Armour, K.E.3    Armour, K.J.4    Reid, D.M.5
  • 31
    • 0037365442 scopus 로고    scopus 로고
    • Precision, accuracy, and reproducibility of dual X-ray absorptiometry measurements in mice in vivo
    • Iida-Klein A., Lu S.S., Yokoyama K., Dempster D.W., Nieves J.W., Lindsay R. Precision, accuracy, and reproducibility of dual X-ray absorptiometry measurements in mice in vivo. J Clin Densitom 2003, 6:25-33.
    • (2003) J Clin Densitom , vol.6 , pp. 25-33
    • Iida-Klein, A.1    Lu, S.S.2    Yokoyama, K.3    Dempster, D.W.4    Nieves, J.W.5    Lindsay, R.6
  • 32
    • 0942268148 scopus 로고    scopus 로고
    • Detecting and tracking local changes in the tibiae of individual rats: a novel method to analyse longitudinal in vivo micro-CT data
    • Waarsing J.H., Day J.S., van der Linden J.C., Ederveen A.G., Spanjers C., De Clerck N., et al. Detecting and tracking local changes in the tibiae of individual rats: a novel method to analyse longitudinal in vivo micro-CT data. Bone 2004, 34:163-169.
    • (2004) Bone , vol.34 , pp. 163-169
    • Waarsing, J.H.1    Day, J.S.2    van der Linden, J.C.3    Ederveen, A.G.4    Spanjers, C.5    De Clerck, N.6
  • 34
    • 0031020931 scopus 로고    scopus 로고
    • A new method for the model-independent assessment of thickness in the three-dimensional images
    • Hildebrand T., Ruegsegger P. A new method for the model-independent assessment of thickness in the three-dimensional images. J Microsc 1997, 185:67-75.
    • (1997) J Microsc , vol.185 , pp. 67-75
    • Hildebrand, T.1    Ruegsegger, P.2
  • 35
    • 0023488581 scopus 로고
    • Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt A.M., Drezner M.K., Glorieux F.H., Kanis J.A., Malluche H., Meunier P.J., et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 1987, 2:595-610.
    • (1987) J Bone Miner Res , vol.2 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3    Kanis, J.A.4    Malluche, H.5    Meunier, P.J.6
  • 36
    • 0027175806 scopus 로고
    • Basic biomechanical measurements of bone: a tutorial
    • Turner C.H., Burr D.B. Basic biomechanical measurements of bone: a tutorial. Bone 1993, 14:595-608.
    • (1993) Bone , vol.14 , pp. 595-608
    • Turner, C.H.1    Burr, D.B.2
  • 38
    • 17644390924 scopus 로고    scopus 로고
    • Genetic variation in structure-function relationships for the inbred mouse lumbar vertebral body
    • Tommasini S.M., Morgan T.G., van der Meulen M.C.h., Jepsen K.J. Genetic variation in structure-function relationships for the inbred mouse lumbar vertebral body. J Bone Miner Res 2005, 20:817-827.
    • (2005) J Bone Miner Res , vol.20 , pp. 817-827
    • Tommasini, S.M.1    Morgan, T.G.2    van der Meulen, M.3    Jepsen, K.J.4
  • 39
    • 1542316258 scopus 로고    scopus 로고
    • Leptin deficiency produces contrasting phenotypes in bones of the limb and spine
    • Hamrick M.W., Pennington C., Newton D., Xie D., Isales C. Leptin deficiency produces contrasting phenotypes in bones of the limb and spine. Bone 2004, 34:376-383.
    • (2004) Bone , vol.34 , pp. 376-383
    • Hamrick, M.W.1    Pennington, C.2    Newton, D.3    Xie, D.4    Isales, C.5
  • 40
    • 77953529587 scopus 로고    scopus 로고
    • Capacity of omega-3 fatty acids or eicosapentaenoic acid to counteract weightlessness-induced bone loss by inhibiting NF-kappaB activation: from cells to bed rest to astronauts
    • Zwart S.R., Pierson D., Mehta S., Gonda S., Smith S.M.. Capacity of omega-3 fatty acids or eicosapentaenoic acid to counteract weightlessness-induced bone loss by inhibiting NF-kappaB activation: from cells to bed rest to astronauts. J Bone Miner Res 2010, 25:1049-1057.
    • (2010) J Bone Miner Res , vol.25 , pp. 1049-1057
    • Zwart, S.R.1    Pierson, D.2    Mehta, S.3    Gonda, S.4    Smith, S.M..5
  • 42
    • 58149292278 scopus 로고    scopus 로고
    • Modulation of inflammatory cytokines by omega-3 fatty acids
    • Kang J.X., Weylandt K.H. Modulation of inflammatory cytokines by omega-3 fatty acids. Subcell Biochem 2008, 49:133-143.
    • (2008) Subcell Biochem , vol.49 , pp. 133-143
    • Kang, J.X.1    Weylandt, K.H.2
  • 43
    • 0141723284 scopus 로고    scopus 로고
    • Reduced bone formation and increased bone resorption: rational targets for the treatment of osteoporosis
    • Seeman E. Reduced bone formation and increased bone resorption: rational targets for the treatment of osteoporosis. Osteoporos Int 2003, 14:S2-S8.
    • (2003) Osteoporos Int , vol.14
    • Seeman, E.1
  • 44
    • 0942290530 scopus 로고    scopus 로고
    • Repletion with (n-3) fatty acids reverses bone structural deficits in (n-3)-deficient rats
    • Reinwald S., Li Y., Moriguchi T., Salem N., Watkins B.A. Repletion with (n-3) fatty acids reverses bone structural deficits in (n-3)-deficient rats. J Nutr 2004, 134:388-394.
    • (2004) J Nutr , vol.134 , pp. 388-394
    • Reinwald, S.1    Li, Y.2    Moriguchi, T.3    Salem, N.4    Watkins, B.A.5
  • 45
    • 0032982438 scopus 로고    scopus 로고
    • Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes
    • Thomas T., Gori F., Khosla S., Jensen M.D., Burguera B., Riggs B.L. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 1999, 140:1630-1638.
    • (1999) Endocrinology , vol.140 , pp. 1630-1638
    • Thomas, T.1    Gori, F.2    Khosla, S.3    Jensen, M.D.4    Burguera, B.5    Riggs, B.L.6
  • 46
    • 0037300892 scopus 로고    scopus 로고
    • Leptin: a potential mediator for protective effects of fat mass on bone tissue
    • Thomas T. Leptin: a potential mediator for protective effects of fat mass on bone tissue. Joint Bone Spine 2003, 70:18-21.
    • (2003) Joint Bone Spine , vol.70 , pp. 18-21
    • Thomas, T.1
  • 49
    • 20444366199 scopus 로고    scopus 로고
    • Fatty acids and expression of adipokines
    • Drevon C.A. Fatty acids and expression of adipokines. Biochim Biophys Acta 2005, 1740:287-292.
    • (2005) Biochim Biophys Acta , vol.1740 , pp. 287-292
    • Drevon, C.A.1
  • 50
    • 70350518559 scopus 로고    scopus 로고
    • Hormones and osteoporosis update. Regulation of bone remodeling by adipokines
    • Takeda S. Hormones and osteoporosis update. Regulation of bone remodeling by adipokines. Clin Calcium 2009, 19:1009-1014.
    • (2009) Clin Calcium , vol.19 , pp. 1009-1014
    • Takeda, S.1
  • 52
    • 33645952372 scopus 로고    scopus 로고
    • The effect of pre- and postmolt diets high in n-3 fatty acids and molt programs on skeletal integrity and insulin-like growth factor-I of White Leghorns
    • Mazzuco H., McMurtry J.P., Kuo A.Y., Hester P.Y. The effect of pre- and postmolt diets high in n-3 fatty acids and molt programs on skeletal integrity and insulin-like growth factor-I of White Leghorns. Poult Sci 2005, 84:1735-1749.
    • (2005) Poult Sci , vol.84 , pp. 1735-1749
    • Mazzuco, H.1    McMurtry, J.P.2    Kuo, A.Y.3    Hester, P.Y.4
  • 53
    • 0034457770 scopus 로고    scopus 로고
    • Dietary protein restriction lowers plasma insulin-like growth factor I (IGF-I), impairs cortical bone formation, and induces osteoblastic resistance to IGF-I in adult female rats
    • Bourrin S., Ammann P., Bonjour J.P., Rizzoli R. Dietary protein restriction lowers plasma insulin-like growth factor I (IGF-I), impairs cortical bone formation, and induces osteoblastic resistance to IGF-I in adult female rats. Endocrinology 2000, 141:3149-3155.
    • (2000) Endocrinology , vol.141 , pp. 3149-3155
    • Bourrin, S.1    Ammann, P.2    Bonjour, J.P.3    Rizzoli, R.4
  • 54
    • 0032404070 scopus 로고    scopus 로고
    • Histomorphometric, physical, and mechanical effects of spaceflight and insulin-like growth factor-I on rat long bones
    • Bateman T.A., Zimmerman R.J., Ayers R.A., Ferguson V.L., Chapes S.K., Simske S.J. Histomorphometric, physical, and mechanical effects of spaceflight and insulin-like growth factor-I on rat long bones. Bone 1998, 23:527-535.
    • (1998) Bone , vol.23 , pp. 527-535
    • Bateman, T.A.1    Zimmerman, R.J.2    Ayers, R.A.3    Ferguson, V.L.4    Chapes, S.K.5    Simske, S.J.6
  • 55
    • 0141638679 scopus 로고    scopus 로고
    • Comparative effects of vitamin K and vitamin D supplementation on prevention of osteopenia in calcium-deficient young rats
    • Iwamoto J., Yeh J.K., Takeda T., Ichimura S., Sato Y. Comparative effects of vitamin K and vitamin D supplementation on prevention of osteopenia in calcium-deficient young rats. Bone 2003, 33:557-566.
    • (2003) Bone , vol.33 , pp. 557-566
    • Iwamoto, J.1    Yeh, J.K.2    Takeda, T.3    Ichimura, S.4    Sato, Y.5
  • 56
    • 43549094971 scopus 로고    scopus 로고
    • Dietary fish oil results in a greater bone mass and bone formation indices in aged ovariectomized rats
    • Matsushita H., Barrios J.A., Shea J.E., Miller S.C. Dietary fish oil results in a greater bone mass and bone formation indices in aged ovariectomized rats. J Bone Miner Metab 2008, 26:241-247.
    • (2008) J Bone Miner Metab , vol.26 , pp. 241-247
    • Matsushita, H.1    Barrios, J.A.2    Shea, J.E.3    Miller, S.C.4
  • 57
    • 33750458990 scopus 로고    scopus 로고
    • Detrimental effect of eicosapentaenoic acid supplementation on bone following ovariectomy in rats
    • Poulsen R.C., Kruger M.C. Detrimental effect of eicosapentaenoic acid supplementation on bone following ovariectomy in rats. Prostaglandins Leukot Essent Fatty Acids 2006, 75:419-427.
    • (2006) Prostaglandins Leukot Essent Fatty Acids , vol.75 , pp. 419-427
    • Poulsen, R.C.1    Kruger, M.C.2
  • 58
    • 77949270860 scopus 로고    scopus 로고
    • Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity
    • Micallef M., Munro I., Phang M., Garg M. Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity. Br J Nutr 2009, 19:1-5.
    • (2009) Br J Nutr , vol.19 , pp. 1-5
    • Micallef, M.1    Munro, I.2    Phang, M.3    Garg, M.4
  • 59
    • 50949110948 scopus 로고    scopus 로고
    • Fish, omega-3 polyunsaturated fatty acids, and mortality from cardiovascular diseases in a nationwide community-based cohort of Japanese men and women the JACC (Japan Collaborative Cohort Study for Evaluation of Cancer Risk) Study
    • Yamagishi K., Iso H., Date C., Fukui M., Wakai K., Kikuchi S., et al. Fish, omega-3 polyunsaturated fatty acids, and mortality from cardiovascular diseases in a nationwide community-based cohort of Japanese men and women the JACC (Japan Collaborative Cohort Study for Evaluation of Cancer Risk) Study. J Am Coll Cardiol 2008, 52:988-996.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 988-996
    • Yamagishi, K.1    Iso, H.2    Date, C.3    Fukui, M.4    Wakai, K.5    Kikuchi, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.