메뉴 건너뛰기




Volumn 49, Issue 3-4, 2011, Pages 165-173

Metabolic profiling of vitamin C deficiency in Gulo-/- mice using proton NMR spectroscopy

Author keywords

Ascorbic acid; Glutathione; Metabolomics; Scurvy; Vitamin C; Vitamin deficiency

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASCORBIC ACID DEFICIENCY; CONTROLLED STUDY; GENE; GULO GENE; KNOCKOUT MOUSE; MALE; METABOLOMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; STATISTICAL MODEL;

EID: 79958772782     PISSN: 09252738     EISSN: 15735001     Source Type: Journal    
DOI: 10.1007/s10858-011-9485-5     Document Type: Article
Times cited : (12)

References (46)
  • 2
    • 19144371287 scopus 로고    scopus 로고
    • NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition
    • DOI 10.1002/nbm.935
    • Bollard ME, Stanley EG, Lindon JC, Nicholson JK, Holmes E (2005) NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition. NMR Biomed 18:143-162 (Pubitemid 40716122)
    • (2005) NMR in Biomedicine , vol.18 , Issue.3 , pp. 143-162
    • Bollard, M.E.1    Stanley, E.G.2    Lindon, J.C.3    Nicholson, J.K.4    Holmes, E.5
  • 3
    • 77956995087 scopus 로고    scopus 로고
    • Vitamin C and cancer: What can we conclude - 1, 609 patients and 33 years later?
    • Cabanillas F (2010) Vitamin C and cancer: what can we conclude - 1, 609 patients and 33 years later? P R Health Sci J 29:215-217
    • (2010) P R Health Sci J , vol.29 , pp. 215-217
    • Cabanillas, F.1
  • 4
    • 34547108613 scopus 로고    scopus 로고
    • Oxidative stress-mediated arterial dysfunction in patients with metabolic syndrome: Effect of ascorbic acid
    • DOI 10.1016/j.freeradbiomed.2007.06.002, PII S0891584907003875
    • Cangemi R, Angelico F, Loffredo L, Del Ben M, Pignatelli P, Martini A, Violi F (2007) Oxidative stress-mediated arterial dysfunction in patients with metabolic syndrome: effect of ascorbic acid. Free Radic Biol Med 43:853-859 (Pubitemid 47102131)
    • (2007) Free Radical Biology and Medicine , vol.43 , Issue.5 , pp. 853-859
    • Cangemi, R.1    Angelico, F.2    Loffredo, L.3    Del, B.M.4    Pignatelli, P.5    Martini, A.6    Violi, F.7
  • 6
    • 33847185621 scopus 로고
    • Biosynthesis of L-ascorbic acid: Missing steps in animals incapable of synthesizing the vitamin
    • Chatterjee IB, Kar NC, Ghosh NC, Guha BC (1961) Biosynthesis of L-ascorbic acid: missing steps in animals incapable of synthesizing the vitamin. Nature 192:163-164
    • (1961) Nature , vol.192 , pp. 163-164
    • Chatterjee, I.B.1    Kar, N.C.2    Ghosh, N.C.3    Guha, B.C.4
  • 9
    • 78650315006 scopus 로고    scopus 로고
    • Systems level studies of mammalian metabolomes: The roles of mass spectrometry and nuclear magnetic resonance spectroscopy
    • Dunn WB, Broadhurst DI, Atherton HJ, Goodacre R, Griffin JL (2011) Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy. Chem Soc Rev 40:387-402
    • (2011) Chem Soc Rev , vol.40 , pp. 387-402
    • Dunn, W.B.1    Broadhurst, D.I.2    Atherton, H.J.3    Goodacre, R.4    Griffin, J.L.5
  • 10
    • 0020089191 scopus 로고
    • Cross-validatory choice of the number of components from a principal component analysis
    • Eastment HT, Krzanowski WJ (1982) Cross-validatory choice of the number of components from a principal component analysis. Technometrics 24:73-77
    • (1982) Technometrics , vol.24 , pp. 73-77
    • Eastment, H.T.1    Krzaonowski, W.J.2
  • 12
    • 65549098273 scopus 로고    scopus 로고
    • Role of marginal vitamin C deficiency in atherogenesis: In vivo models and clinical studies
    • Frikke-Schmidt H, Lykkesfeldt J (2009) Role of marginal vitamin C deficiency in atherogenesis: in vivo models and clinical studies. Basic Clin Pharmacol Toxicol 104:419-433
    • (2009) Basic Clin Pharmacol Toxicol , vol.104 , pp. 419-433
    • Frikke-Schmidt, H.1    Lykkesfeldt, J.2
  • 13
    • 77956623471 scopus 로고    scopus 로고
    • Diet and cancer prevention: Contributions from the European Prospective Investigation into Cancer and Nutrition (EPIC) study
    • Gonzalez C, Riboli E (2010) Diet and cancer prevention: contributions from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Eur J Cancer 46:2555-2562
    • (2010) Eur J Cancer , vol.46 , pp. 2555-2562
    • Gonzalez, C.1    Riboli, E.2
  • 14
    • 33746065648 scopus 로고    scopus 로고
    • Understanding mouse models of disease through metabolomics
    • Griffin JL (2006) Understanding mouse models of disease through metabolomics. Curr Opin Chem Biol 10:309-315
    • (2006) Curr Opin Chem Biol , vol.10 , pp. 309-315
    • Griffin, J.L.1
  • 15
    • 1242316274 scopus 로고    scopus 로고
    • Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine L-gulono-gamma-lactone oxidase
    • DOI 10.1016/j.ygeno.2003.08.018
    • Ha MN, Graham FL, D'Souza CK, Muller WJ, Igdoura SA, Schellhorn HE (2004) Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine l-gulono-gamma-lactone oxidase. Genomics 83:482-492 (Pubitemid 38220853)
    • (2004) Genomics , vol.83 , Issue.3 , pp. 482-492
    • Ha, M.N.1    Graham, F.L.2    D'Souza, C.K.3    Muller, W.J.4    Igdoura, S.A.5    Schellhorn, H.E.6
  • 16
    • 77955665514 scopus 로고    scopus 로고
    • Low ascorbic acid and increased oxidative stress in gulo(-/-) mice during development
    • Harrison FE, Meredith ME, Dawes SM, Saskowski JL, May JM (2010) Low ascorbic acid and increased oxidative stress in gulo(-/-) mice during development. Brain Res 1349:143-152
    • (2010) Brain Res , vol.1349 , pp. 143-152
    • Harrison, F.E.1    Meredith, M.E.2    Dawes, S.M.3    Saskowski, J.L.4    May, J.M.5
  • 18
    • 33845354407 scopus 로고    scopus 로고
    • Role of uric acid in hypertension, renal disease, and metabolic syndrome
    • Heinig M, Johnson RJ (2006) Role of uric acid in hypertension, renal disease, and metabolic syndrome. Cleve Clin J Med 73:1059-1064 (Pubitemid 44883981)
    • (2006) Cleveland Clinic Journal of Medicine , vol.73 , Issue.12 , pp. 1059-1064
    • Heinig, M.1    Johnson, R.J.2
  • 19
    • 0030760597 scopus 로고    scopus 로고
    • Vitamin C supplementation and the common cold-was Linus Pauling right or wrong?
    • Hemilä H (1997) Vitamin C supplementation and the common cold-was Linus Pauling right or wrong? Int J Vitam Nutr Res 67:329-335
    • (1997) Int J Vitam Nutr Res , vol.67 , pp. 329-335
    • Hemilä, H.1
  • 21
    • 72649106550 scopus 로고    scopus 로고
    • A novel component of the metabolic syndrome: The oxidative stress
    • Hopps E, Noto D, Caimi G, Averna MR (2010) A novel component of the metabolic syndrome: the oxidative stress. Nutr Metab Cardiovasc Dis 20:72-77
    • (2010) Nutr Metab Cardiovasc Dis , vol.20 , pp. 72-77
    • Hopps, E.1    Noto, D.2    Caimi, G.3    Averna, M.R.4
  • 22
    • 0242408870 scopus 로고    scopus 로고
    • The Whole Structure of the Human Nonfunctional L-Gulono-gamma-Lactone Oxidase Gene - The Gene Responsible for Scurvy - And the Evolution of Repetitive Sequences Thereon
    • Inai Y, Ohta Y, Nishikimi M (2003) The whole structure of the human nonfunctional L-gulono-gamma-lactone oxidase gene-the gene responsible for scurvy-and the evolution of repetitive sequences thereon. J Nutr Sci Vitaminol 49:315-319 (Pubitemid 37433096)
    • (2003) Journal of Nutritional Science and Vitaminology , vol.49 , Issue.5 , pp. 315-319
    • Inai, Y.1    Ohta, Y.2    Nishikimi, M.3
  • 23
    • 75549090213 scopus 로고    scopus 로고
    • KEGG for representation and analysis of molecular networks involving diseases and drugs
    • Kanehisa M, Goto S, Furumichi M, Tanabe M, Hirakawa M (2010) KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res 38:D355-D360
    • (2010) Nucleic Acids Res , vol.38
    • Kanehisa, M.1    Goto, S.2    Furumichi, M.3    Tanabe, M.4    Hirakawa, M.5
  • 24
    • 0034109403 scopus 로고    scopus 로고
    • Antioxidant ability of caffeine and its metabolites based on the study of oxygen radical absorbing capacity and inhibition of LDL peroxidation
    • Lee C (2000) Antioxidant ability of caffeine and its metabolites based on the study of oxygen radical absorbing capacity and inhibition of LDL peroxidation. Clin Chim Acta 295:141-154
    • (2000) Clin Chim Acta , vol.295 , pp. 141-154
    • Lee, C.1
  • 25
    • 57749195315 scopus 로고    scopus 로고
    • Restoration of vitamin C synthesis in transgenic Gulo-/- mice by helper-dependent adenovirus-based expression of gulonolactone oxidase
    • Li Y, Shi CX, Mossman KL, Rosenfeld J, Boo YC, Schellhorn HE (2008) Restoration of vitamin C synthesis in transgenic Gulo-/- mice by helper-dependent adenovirus-based expression of gulonolactone oxidase. Hum Gene Ther 19:1349-1358
    • (2008) Hum Gene Ther , vol.19 , pp. 1349-1358
    • Li, Y.1    Shi, C.X.2    Mossman, K.L.3    Rosenfeld, J.4    Boo, Y.C.5    Schellhorn, H.E.6
  • 27
    • 3042559581 scopus 로고    scopus 로고
    • Vitamin C in human health and disease is still a mystery? An overview
    • Naidu KA (2003) Vitamin C in human health and disease is still a mystery? An overview. Nutr J 2:7
    • (2003) Nutr J , vol.2 , pp. 7
    • Naidu, K.A.1
  • 29
    • 0025885658 scopus 로고
    • Molecular basis for the deficiency in humans of gulonolactone oxidase, a key enzyme for ascorbic acid biosynthesis
    • Nishikimi M, Yagi K (1991) Molecular basis for the deficiency in humans of gulonolactone oxidase, a key enzyme for ascorbic acid biosynthesis. Am J Clin Nutr 54:1203S-1208S
    • (1991) Am J Clin Nutr , vol.54
    • Nishikimi, M.1    Yagi, K.2
  • 30
    • 0026787756 scopus 로고
    • Guinea pigs possess a highly mutated gene for L-gulono-gamma-lactone oxidase, the key enzyme for L-ascorbic acid biosynthesis missing in this species
    • Nishikimi M, Kawai T, Yagi K (1992) Guinea pigs possess a highly mutated gene for L-gulono-gamma-lactone oxidase, the key enzyme for L-ascorbic acid biosynthesis missing in this species. J Biol Chem 267:21967-21972
    • (1992) J Biol Chem , vol.267 , pp. 21967-21972
    • Nishikimi, M.1    Kawai, T.2    Yagi, K.3
  • 31
    • 0028228342 scopus 로고
    • Cloning and chromosomal mapping of the human nonfunctional gene for L-gulono-gamma-lactone oxidase, the enzyme for L-ascorbic acid biosynthesis missing in man
    • Nishikimi M, Fukuyama R, Minoshima S, Shimizu N, Yagi K (1994) Cloning and chromosomal mapping of the human nonfunctional gene for L-gulono-gamma- lactone oxidase, the enzyme for L-ascorbic acid biosynthesis missing in man. J Biol Chem 269:13685-13688
    • (1994) J Biol Chem , vol.269 , pp. 13685-13688
    • Nishikimi, M.1    Fukuyama, R.2    Minoshima, S.3    Shimizu, N.4    Yagi, K.5
  • 32
    • 0025012192 scopus 로고
    • Cellular functions of ascorbic acid
    • Padh H (1990) Cellular functions of ascorbic acid. Biochem Cell Biol 68:1166-1173
    • (1990) Biochem Cell Biol , vol.68 , pp. 1166-1173
    • Padh, H.1
  • 33
    • 0027930182 scopus 로고
    • Pharmacology of vitamin C
    • Sauberlich HE (1994) Pharmacology of vitamin C. Annu Rev Nutr 14:371-391
    • (1994) Annu Rev Nutr , vol.14 , pp. 371-391
    • Sauberlich, H.E.1
  • 34
    • 78649856207 scopus 로고    scopus 로고
    • Quantitative metabolomic profiling of serum and urine in DSS-induced ulcerative colitis of mice by 1H NMR spectroscopy
    • Schicho R, Nazyrova A, Shaykhutdinov R, Duggan G, Vogel HJ and Storr M (2010) Quantitative metabolomic profiling of serum and urine in DSS-induced ulcerative colitis of mice by 1H NMR spectroscopy. J Proteome Res 9:6265-6273
    • (2010) J Proteome Res , vol.9 , pp. 6265-6273
    • Schicho, R.1    Nazyrova, A.2    Shaykhutdinov, R.3    Duggan, G.4    Vogel, H.J.5    Storr, M.6
  • 37
    • 0031938879 scopus 로고    scopus 로고
    • Ascorbate-induced oxidative inactivation of Zn2 + - glycerophosphocholine cholinephosphodiesterase
    • Sok D (2002) Ascorbate-induced oxidative inactivation of Zn2 + - glycerophosphocholine cholinephosphodiesterase. J Neurochem 70:1167-1174
    • (2002) J Neurochem , vol.70 , pp. 1167-1174
    • Sok, D.1
  • 38
    • 0018581624 scopus 로고
    • Homo sapiens ascorbicus, a biochemically corrected robust human mutant
    • Stone I (1979) Homo sapiens ascorbicus, a biochemically corrected robust human mutant. Med Hypotheses 5:711-721
    • (1979) Med Hypotheses , vol.5 , pp. 711-721
    • Stone, I.1
  • 39
  • 40
    • 0036083139 scopus 로고    scopus 로고
    • Orthogonal projections to latent structures (O-PLS)
    • Trygg J, Wold S (2002) Orthogonal projections to latent structures (O-PLS). J Chemometrics 16:119-128
    • (2002) J Chemometrics , vol.16 , pp. 119-128
    • Trygg, J.1    Wold, S.2
  • 42
    • 34247854781 scopus 로고    scopus 로고
    • Ascorbate deficiency results in impaired neutrophil apoptosis and clearance and is associated with up-regulation of hypoxia-inducible factor 1alpha
    • DOI 10.1189/jlb.0806541
    • Vissers MC, Wilkie RP (2007) Ascorbate deficiency results in impaired neutrophil apoptosis and clearance and is associated with up-regulation of hypoxia-inducible factor 1alpha. J Leukoc Biol 81:1236-1244 (Pubitemid 46702042)
    • (2007) Journal of Leukocyte Biology , vol.81 , Issue.5 , pp. 1236-1244
    • Vissers, M.C.M.1    Wilkie, R.P.2
  • 43
    • 33745700438 scopus 로고    scopus 로고
    • Targeted profiling: Quantitative analysis of 1H NMR metabolomics data
    • Weljie AM, Newton J, Mercier P, Carlson E, Slupsky CM (2006) Targeted profiling: quantitative analysis of 1H NMR metabolomics data. Anal Chem 78:4430-4442
    • (2006) Anal Chem , vol.78 , pp. 4430-4442
    • Weljie, A.M.1    Newton, J.2    Mercier, P.3    Carlson, E.4    Slupsky, C.M.5
  • 45
    • 0027935268 scopus 로고
    • The redox couple between glutathione and ascorbic acid: A chemical and physiological perspective
    • DOI 10.1016/0891-5849(94)90019-1
    • Winkler BS, Orselli SM, Rex TS (1994) The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective. Free Radic Biol Med 17:333-349 (Pubitemid 24296153)
    • (1994) Free Radical Biology and Medicine , vol.17 , Issue.4 , pp. 333-349
    • Winkler, B.S.1    Orselli, S.M.2    Rex, T.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.