Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine L-gulono-γ-lactone oxidase

Genomics

Volumn 83, Issue 3, 2004, Pages 482-492

  Ha, Michael N ^a   Graham, Frank L ^a   D'Souza, Chantalle K ^a   Muller, William J ^a   Igdoura, Suleiman A ^a   Schellhorn, Herb E ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Adenovirus; Ascorbic acid; GULO; Metabolism; Scurvy; Vitamin C

Indexed keywords

ADENOVIRUS VECTOR; ASCORBIC ACID; COMPLEMENTARY DNA; CRE RECOMBINASE; FLAVINE ADENINE NUCLEOTIDE; GULONOLACTONE OXIDASE; RECOMBINANT PROTEIN;

AMINO ACID COMPOSITION; ARTICLE; ASCORBIC ACID DEFICIENCY; BIOSYNTHESIS; CELL FREE SYSTEM; CELL GROWTH; CONTROLLED STUDY; CYTOMEGALOVIRUS; DNA FLANKING REGION; EMBRYO; EXON; FIBROBLAST; GENE CONSTRUCT; GENE EXPRESSION; GENETIC CODE; GENETIC TRANSCRIPTION; GROWTH INHIBITION; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; INTRON; KIDNEY CELL; LIVER; MOLECULAR CLONING; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; VIROGENESIS; VIRUS REPLICATION;

ADENOVIRIDAE; CYTOMEGALOVIRUS; GULO; MAIZE CHLOROTIC MOTTLE VIRUS; MAMMALIA; MOUSE CYTOMEGALOVIRUS 1; MURINAE; PRIMATES;

EID: 1242316274     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ygeno.2003.08.018     Document Type: Article

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