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Volumn 23, Issue SUPPL. 1, 2011, Pages 1-12

An evaluation of the toxicity of 95 ingredients added individually to experimental cigarettes: Approach and methods

Author keywords

Cigarette ingredients; in vitro in vivo toxicology; smoke chemistry; toxicological testing

Indexed keywords

1,3 BUTADIENE; 2 NITROPROPANE; ALDEHYDE; AMMONIUM HYDROXIDE; AROMATIC AMINE; BENZALDEHYDE; BENZENE; BENZYL ALCOHOL; CARBOHYDRATE; CARBON MONOXIDE; CARBONYL DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; CIGARETTE SMOKE; CINNAMALDEHYDE; ESSENTIAL OIL; EUGENOL; HETEROCYCLIC NITRO COMPOUND; HYDROGEN CYANIDE; ISOPRENE; MALTODEXTRIN; MALTOL; NICOTINE; NITROGEN OXIDE; NITROSAMINE; ORGANIC COMPOUND; PHENOL DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON; RESIN; TAR; VOLATILE AGENT;

EID: 79958720434     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2010.543187     Document Type: Article
Times cited : (37)

References (64)
  • 1
    • 0006896732 scopus 로고
    • AALAS American Association for Laboratory Animals Science Policy on the Humane Care and Use of Laboratory Animals
    • AALAS. 1991. American Association for Laboratory Animals Science Policy on the Humane Care and Use of Laboratory Animals. Lab Anim Sci 41:91
    • (1991) Lab Anim Sci , vol.41 , pp. 91
  • 2
    • 0002873523 scopus 로고    scopus 로고
    • Smoke chemistry
    • Davis DL, Nielsen MT, eds. Oxford Blackwell Science
    • Baker RR. 1999. Smoke chemistry. In: Davis DL, Nielsen MT, eds. Tobacco: Production, Chemistry, and Technology. Oxford: Blackwell Science, 398-439
    • (1999) Tobacco: Production, Chemistry, and Technology , pp. 398-439
    • Baker, R.R.1
  • 3
    • 7444236652 scopus 로고    scopus 로고
    • The development and significance of standards for smoking-machine methodology
    • Baker RR. 2002. The development and significance of standards for smoking-machine methodology. Beitr Tabakforsch Int 20:23-41
    • (2002) Beitr Tabakforsch Int , vol.20 , pp. 23-41
    • Baker, R.R.1
  • 4
    • 1842419474 scopus 로고    scopus 로고
    • The pyrolysis of tobacco ingredients
    • Baker RR, Bishop LJ 2004. The pyrolysis of tobacco ingredients. J Anal App Pyrol 71 223-311
    • (2004) J Anal App Pyrol , vol.71 , pp. 223-311
    • Baker, R.R.1    Bishop, L.J.2
  • 5
    • 1842609944 scopus 로고    scopus 로고
    • An overview of the effects of tobacco ingredients on smoke chemistry and toxicity
    • DOI 10.1016/j.fct.2004.01.001, PII S0278691504000043
    • Baker RR, Massey ED, Smith G 2004. An overview of the effects of tobacco ingredients on smoke chemistry and toxicity. Food Chem Toxicol 42 Suppl S53-S83 (Pubitemid 38456980)
    • (2004) Food and Chemical Toxicology , vol.42 , Issue.SUPPL.
    • Baker, R.R.1    Massey, E.D.2    Smith, G.3
  • 6
    • 0033144863 scopus 로고    scopus 로고
    • The future of tobacco product regulation and labelling in Europe: Implications for the forthcoming European
    • Union directive
    • Bates C, McNeill A, Jarvis M, Gray N. 1999. The future of tobacco product regulation and labelling in Europe: implications for the forthcoming European Union directive. Tob Control 8:225-235
    • (1999) Tob Control , vol.8 , pp. 225-235
    • Bates, C.1    McNeill, A.2    Jarvis, M.3    Gray, N.4
  • 7
    • 0002458409 scopus 로고    scopus 로고
    • National Cancer Institute. Risks Associated with Smoking Cigarettes with Low Machine-measured Yields of Tar and Nicotine. Smoking and Tobacco Control Monograph Bethesda, MD U.S. Department of Health and Human Services, National Institutes of Health, NIH Publication No 02-5074, October 2001
    • Benowitz NL. 2001. Compensatory smoking of low-yield cigarettes. In: National Cancer Institute. Risks Associated with Smoking Cigarettes with Low Machine-measured Yields of Tar and Nicotine. Smoking and Tobacco Control Monograph No. 13. Bethesda, MD: U.S. Department of Health and Human Services, National Institutes of Health, NIH Publication No. 02-5074, October 2001, 39-63
    • (2001) Compensatory Smoking of Low-yield Cigarettes , Issue.13 , pp. 39-63
    • Benowitz, N.L.1
  • 8
    • 0021990499 scopus 로고
    • Toxicity determined in vitro by morphological alterations and neutral red absorption
    • DOI 10.1016/0378-4274(85)90046-3
    • Borenfreund E, Puerner JA. 1985. Toxicity determined in vitro by morphological alterations and neutral red absorption. Toxicol Lett 24:119-124 (Pubitemid 15103513)
    • (1985) Toxicology Letters , vol.24 , Issue.2-3 , pp. 119-124
    • Borenfreund, E.1    Puerner, J.A.2
  • 10
    • 0000744925 scopus 로고
    • Nature of cigaret smoke Technic of experimental smoking
    • Bradford JA, Harlan WR, Hanmer HR. 1936. Nature of cigaret smoke. Technic of experimental smoking. Ind Eng Chem 28:836-839
    • (1936) Ind Eng Chem , vol.28 , pp. 836-839
    • Bradford, J.A.1    Harlan, W.R.2    Hanmer, H.R.3
  • 12
    • 0036133235 scopus 로고    scopus 로고
    • Evaluation of the potential effects of ingredients added to cigarettes. Part 1: Cigarette design, testing approach, and review of results
    • DOI 10.1016/S0278-6915(01)00084-9, PII S0278691501000849
    • Carmines EL. 2002. Evaluation of the potential effects of ingredients added to cigarettes. Part 1: cigarette design, testing approach, and review of results. Food Chem Toxicol 40:77-91 (Pubitemid 33132143)
    • (2002) Food and Chemical Toxicology , vol.40 , Issue.1 , pp. 77-91
    • Carmines, E.L.1
  • 13
    • 21844479263 scopus 로고    scopus 로고
    • Toxicological evaluation of glycerin as a cigarette ingredient
    • DOI 10.1016/j.fct.2005.04.010, PII S0278691505001432
    • Carmines EL, Gaworski CL. 2005. Toxicological evaluation of glycerin as a cigarette ingredient. Food Chem Toxicol 43:1521-1539 (Pubitemid 40961914)
    • (2005) Food and Chemical Toxicology , vol.43 , Issue.10 , pp. 1521-1539
    • Carmines, E.L.1    Gaworski, C.L.2
  • 14
    • 21244432631 scopus 로고    scopus 로고
    • Toxicologic evaluation of licorice extract as a cigarette ingredient
    • DOI 10.1016/j.fct.2005.01.012, PII S027869150500044X
    • Carmines EL, Lemus R, Gaworski CL. 2005. Toxicologic evaluation of licorice extract as a cigarette ingredient. Food Chem Toxicol 43:1303-1322 (Pubitemid 40884606)
    • (2005) Food and Chemical Toxicology , vol.43 , Issue.9 , pp. 1303-1322
    • Carmines, E.L.1    Lemus, R.2    Gaworski, C.L.3
  • 15
    • 77957560928 scopus 로고    scopus 로고
    • A further review of inhalation studies with cigarette smoke and lung cancer in experimental animals, including transgenic mice
    • Coggins CR. 2010. A further review of inhalation studies with cigarette smoke and lung cancer in experimental animals, including transgenic mice. Inhal Toxicol 22:974-983
    • (2010) Inhal Toxicol , vol.22 , pp. 974-983
    • Coggins, C.R.1
  • 16
    • 0019415769 scopus 로고
    • Measurement of respiratory patterns in rodents using whole-body plethysmography and a pneumotachograph
    • Coggins CRE, Duchosal F, Musy C, Ventrone R. 1981. Measurement of respiratory patterns in rodents, using whole-body plethysmography and a pneumotachograph. Lab Animal 15:137-140 (Pubitemid 11073493)
    • (1981) Laboratory Animals , vol.15 , Issue.2 , pp. 137-140
    • Coggins, C.R.E.1    Duchosal, F.2    Musy, C.3    Ventrone, R.4
  • 17
    • 0004132384 scopus 로고
    • Lexington, KY: University of Kentucky Printing Services
    • Diana JN, Vaught A. 1990. Research Cigarettes. Lexington, KY: University of Kentucky Printing Services
    • (1990) Research Cigarettes
    • Diana, J.N.1    Vaught, A.2
  • 19
    • 13144283925 scopus 로고
    • A safety assessment of ingredients added to tobacco in the manufacture of cigarettes
    • Doull J, Frawley JP, George W, Loomis T, Squire RA. 1994. A safety assessment of ingredients added to tobacco in the manufacture of cigarettes. Tob J Int 196:32-39
    • (1994) Tob J Int , vol.196 , pp. 32-39
    • Doull, J.1    Frawley, J.P.2    George, W.3    Loomis, T.4    Squire, R.A.5
  • 20
    • 0002150694 scopus 로고
    • Methods of collection of smoke for analytical purposes
    • Dube MF, Green CR. 1982. Methods of collection of smoke for analytical purposes. Rec Adv Tob Sci 8:42-102
    • (1982) Rec Adv Tob Sci , vol.8 , pp. 42-102
    • Dube, M.F.1    Green, C.R.2
  • 21
  • 22
    • 0009663357 scopus 로고
    • A multiple comparison procedure for comparing several treatments with a control
    • Dunnett CW. 1955. A multiple comparison procedure for comparing several treatments with a control. J Am Stat Assoc 50:1096-1121
    • (1955) J Am Stat Assoc , vol.50 , pp. 1096-1121
    • Dunnett, C.W.1
  • 24
    • 36849056604 scopus 로고    scopus 로고
    • Toxicological evaluation of potassium sorbate added to cigarette tobacco
    • DOI 10.1016/j.fct.2007.08.012, PII S0278691507003018
    • Gaworski CL, Lemus-Olalde R, Carmines EL. 2008. Toxicological evaluation of potassium sorbate added to cigarette tobacco. Food Chem Toxicol 46:339-351 (Pubitemid 350235778)
    • (2008) Food and Chemical Toxicology , vol.46 , Issue.1 , pp. 339-351
    • Gaworski, C.L.1    Lemus-Olalde, R.2    Carmines, E.L.3
  • 25
    • 77949539330 scopus 로고    scopus 로고
    • Toxicological considerations on the use of propylene glycol as a humectant in cigarettes
    • Gaworski CL, Oldham MJ, Coggins CR. 2010. Toxicological considerations on the use of propylene glycol as a humectant in cigarettes. Toxicology 269:54-66
    • (2010) Toxicology , vol.269 , pp. 54-66
    • Gaworski, C.L.1    Oldham, M.J.2    Coggins, C.R.3
  • 27
    • 0036845623 scopus 로고    scopus 로고
    • Toxicologic evaluation of humectants added to cigarette tobacco: 13-week smoke inhalation study of glycerin and propylene glycol in Fischer 344 rats
    • Heck JD, Gaworski CL, Rajendran N, Morrissey RL. 2002. Toxicologic evaluation of humectants added to cigarette tobacco: 13-week smoke inhalation study of glycerin and propylene glycol in Fischer 344 rats. Inhal Toxicol 14:1135-1152
    • (2002) Inhal Toxicol , vol.14 , pp. 1135-1152
    • Heck, J.D.1    Gaworski, C.L.2    Rajendran, N.3    Morrissey, R.L.4
  • 39
    • 84945049658 scopus 로고
    • Quantitative determination of carbon monoxide in blood by gaschromatography
    • Klimisch HJ, Meissner K, Wernicke H. 1974. Quantitative determination of carbon monoxide in blood by gaschromatography. Z Klin Chem Klin Biochem 12:535-538
    • (1974) Z Klin Chem Klin Biochem , vol.12 , pp. 535-538
    • Klimisch, H.J.1    Meissner, K.2    Wernicke, H.3
  • 40
    • 0014663107 scopus 로고
    • Goblet cell increase in rat bronchial epithelium after exposure to cigarette and cigar tobacco smoke
    • Lamb D, Reid L. 1969. Goblet cell increase in rat bronchial epithelium after exposure to cigarette and cigar tobacco smoke. Br Med J 1:33-35
    • (1969) Br Med J , vol.1 , pp. 33-35
    • Lamb, D.1    Reid, L.2
  • 41
    • 0018872666 scopus 로고
    • Small animal inhalation chambers and the significance of dust ingestion from the contaminated coat when exposing rats to zinc chromate
    • Langård S, Nordhagen AL. 1980. Small animal inhalation chambers and the significance of dust ingestion from the contaminated coat when exposing rats to zinc chromate. Acta Pharmacol Toxicol (Copenh) 46:43-46 (Pubitemid 10202910)
    • (1980) Acta Pharmacologica et Toxicologica , vol.46 , Issue.1 , pp. 43-46
    • Langard, S.1    Nordhagen, A.L.2
  • 42
    • 70350594380 scopus 로고    scopus 로고
    • Does use of flue-cured rather than blended cigarettes affect international variation in mortality from lung cancer and COPD?
    • Lee PN, Forey BA, Fry JS, Hamling JS, Hamling JF, Sanders EB, Carchman RA. 2009. Does use of flue-cured rather than blended cigarettes affect international variation in mortality from lung cancer and COPD? Inhal Toxicol 21:404-430
    • (2009) Inhal Toxicol , vol.21 , pp. 404-430
    • Lee, P.N.1    Forey, B.A.2    Fry, J.S.3    Hamling, J.S.4    Hamling, J.F.5    Sanders, E.B.6    Carchman, R.A.7
  • 45
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W. 1959. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 22:719-748
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 46
    • 0020533372 scopus 로고
    • Revised methods for the Salmonella mutagenicity test
    • Maron DM, Ames BN. 1983. Revised methods for the Salmonella mutagenicity test. Mutat Res 113:173-215 (Pubitemid 13120319)
    • (1983) Mutation Research , vol.113 , Issue.3-4 , pp. 173-215
    • Maron, D.M.1    Ames, B.N.2
  • 47
    • 79958732407 scopus 로고
    • OECD OECD Guideline for the testing of chemicals. Paris France
    • OECD. 1981. No. 413. Subchronic inhalation toxicity: 90-day study. In: OECD Guideline for the testing of chemicals. Paris, France
    • (1981) Subchronic Inhalation Toxicity: 90-day Study , Issue.413
  • 48
    • 79958735833 scopus 로고    scopus 로고
    • OECD OECD guideline for testing of chemicals. Paris France
    • OECD. 1997. No. 471. Bacterial reverse mutation test. In: OECD guideline for testing of chemicals. Paris, France
    • (1997) Bacterial Reverse Mutation Test , Issue.471
  • 49
    • 79958703645 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals. Paris
    • Draft proposal for a revised Guideline 413. In
    • OECD. 2008. Draft proposal for a revised Guideline 413. In: OECD guideline for the testing of chemicals. Paris, France
    • (2008) France
  • 50
    • 0242323848 scopus 로고    scopus 로고
    • Effects of ingredients on cigarette smoke composition and biological activity: A literature overview
    • Paschke T, Scherer G, Heller WD. 2002. Effects of ingredients on cigarette smoke composition and biological activity: a literature overview. Beitr Tabakforsch Int 20:107-247
    • (2002) Beitr Tabakforsch Int , vol.20 , pp. 107-247
    • Paschke, T.1    Scherer, G.2    Heller, W.D.3
  • 51
    • 33646817063 scopus 로고    scopus 로고
    • Types and patterns of response in the larynx following inhalation
    • Renne RA, Gideon KM. 2006. Types and patterns of response in the larynx following inhalation. Toxicol Pathol 34:281-285
    • (2006) Toxicol Pathol , vol.34 , pp. 281-285
    • Renne, R.A.1    Gideon, K.M.2
  • 53
    • 33845486743 scopus 로고    scopus 로고
    • Some studies on the effects of additives on cigarette mainstream smoke properties. III. Ingredients reportedly used in various commercial cigarette products in the USA and elsewhere
    • Rodgman A. 2004. Some studies on the effects of additives on cigarette mainstream smoke properties. III. Ingredients reportedly used in various commercial cigarette products in the USA and elsewhere. Beitr Tabakforsch Int 21:47-104
    • (2004) Beitr Tabakforsch Int , vol.21 , pp. 47-104
    • Rodgman, A.1
  • 55
    • 0036132804 scopus 로고    scopus 로고
    • Evaluation of the potential effects of ingredients added to cigarettes. Part 3: In vitro genotoxicity and cytotoxicity
    • DOI 10.1016/S0278-6915(01)00086-2, PII S0278691501000862
    • Roemer E, Tewes FJ, Meisgen TJ, Veltel DJ, Carmines EL. 2002. Evaluation of the potential effects of ingredients added to cigarettes. Part 3: in vitro genotoxicity and cytotoxicity. Food Chem Toxicol 40:105-111 (Pubitemid 33132145)
    • (2002) Food and Chemical Toxicology , vol.40 , Issue.1 , pp. 105-111
    • Roemer, E.1    Tewes, F.J.2    Meisgen, T.J.3    Veltel, D.J.4    Carmines, E.L.5
  • 56
    • 0027533282 scopus 로고
    • High-performance liquid chromatographic determination of nicotine and its urinary metabolites via their 1,3-diethyl-2-thiobarbituric acid derivatives
    • DOI 10.1016/0378-4347(93)80201-E
    • Rustemeier K, Demetriou D, Schepers G, Voncken P. 1993. Highperformance liquid chromatographic determination of nicotine and its urinary metabolites via their 1,3-diethyl-2-thiobarbituric acid derivatives. J Chromatogr 613:95-103 (Pubitemid 23074351)
    • (1993) Journal of Chromatography - Biomedical Applications , vol.613 , Issue.1 , pp. 95-103
    • Rustemeier, K.1    Demetriou, D.2    Schepers, G.3    Voncken, P.4
  • 58
    • 0037009836 scopus 로고    scopus 로고
    • Tobacco smoking, harm reduction, and biomarkers
    • Shields PG. 2002. Tobacco smoking, harm reduction, and biomarkers. J Natl Cancer Inst 94:1435-1444 (Pubitemid 35243742)
    • (2002) Journal of the National Cancer Institute , vol.94 , Issue.19 , pp. 1435-1444
    • Shields, P.G.1
  • 60
    • 0037152649 scopus 로고    scopus 로고
    • Tobacco use and cancer: An epidemiologic perspective for geneticists
    • DOI 10.1038/sj.onc.1205807
    • Thun MJ, Henley SJ, Calle EE. 2002. Tobacco use and cancer: an epidemiologic perspective for geneticists. Oncogene 21:7307-7325 (Pubitemid 35314509)
    • (2002) Oncogene , vol.21 , Issue.48 REV. ISS. 6 , pp. 7307-7325
    • Thun, M.J.1    Henley, S.J.2    Calle, E.E.3
  • 64
    • 77957177877 scopus 로고
    • Histopathologic examination of the rat nasal cavity
    • Young JT. 1981. Histopathologic examination of the rat nasal cavity. Fundam Appl Toxicol 1:309-312
    • (1981) Fundam Appl Toxicol , vol.1 , pp. 309-312
    • Young, J.T.1


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