SCOPUS 정보 검색 플랫폼

Volumn 46, Issue 8, 2011, Pages 3237-3249

A class of oral N-[(1S,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3- carbonyl]- N′-(amino-acid-acyl)hydrazine: Discovery, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis

(7) Yao, Kun a Zhao, Ming a Zhang, Xiaoyi a Wang, Yuji a Li, Li a Zheng, Meiqing a Peng, Shiqi a

a CAPITAL MEDICAL UNIVERSITY (China)

Author keywords

3D QSAR; Anti platelet aggregation; Anti thrombotic activity; Conformation analysis; Tetrahydro carboline

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; BETA CARBOLINE DERIVATIVE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' [(BETA OBZL) ASPARTYL]HYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' ALANYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' ASPARAGINYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' GLUTAMINYL]HYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' HISTIDYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' ISOLEUCYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' LEUCYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' LYSYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' METHIONYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' PHENYLALANYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' PROLYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' SERYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' THREONYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' TRYPTOPHANYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' TYROSYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE 3 CARBONYL] N' VALYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CABOLINE BETA CARBONYL] N' GLYCYLHYDRAZINE; N [1 METHYL 1,2,3,4 TETRAHYDRO BETA CARBOLINE 3 CARBONYL] N' (AMINO ACID ACYL)HYDRAZINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; THROMBOCYTE AGGREGATION;

ADMINISTRATION, ORAL; AMINO ACIDS; ANIMALS; CARBOLINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; FIBRINOLYTIC AGENTS; HUMANS; HYDRAZINES; INHIBITORY CONCENTRATION 50; MALE; MODELS, ANIMAL; MOLECULAR DYNAMICS SIMULATION; PLATELET AGGREGATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; RATS, WISTAR; SWINE; THROMBOSIS;

EID: 79958263530 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2011.04.037 Document Type: Article

Times cited : (46)

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