Refinement of the Dermal Sensitisation Threshold (DST) approach using a larger dataset and incorporating mechanistic chemistry domains

Regulatory Toxicology and Pharmacology

Volumn 60, Issue 2, 2011, Pages 218-224

  Safford, R J ^a   Aptula, A O ^a   Gilmour, N ^a  

^a UNILEVER RESEARCH   (United Kingdom)

Author keywords

Dermal Sensitisation Threshold (DST); Local Lymph Node Assay (LLNA); Non animal methods; Quantitative Risk Assessment (QRA); Sensitisation risk assessment; Skin sensitisation

Indexed keywords

ALLERGEN; CHEMICAL AGENT; FRAGRANCE;

ARTICLE; CHEMISTRY; CLASSIFICATION; CONTROLLED STUDY; DATA BASE; DERMAL SENSITISATION THRESHOLD; EXPERIMENTAL ANIMAL; PRIORITY JOURNAL; PRODUCT SAFETY; QUALITY CONTROL; REFERENCE VALUE; RISK ASSESSMENT; SKIN SENSITIZATION;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; ANIMALS; CONSUMER PRODUCT SAFETY; HUMANS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PERFUME; RISK ASSESSMENT; SKIN TESTS; TOXICITY TESTS;

ANIMALIA;

EID: 79958254928     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2011.03.009     Document Type: Article

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