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Volumn 36, Issue 5, 2008, Pages 557-568

Assuring consumer safety without animal testing: A feasibility case study for skin sensitisation

Author keywords

Allergic contact dermatitis; Alternatives; Animal testing; Consumer safety; Cosmetic testing; Genomics; In silico; In vitro; Proteomics; Risk assessment; Skin allergy; Skin sensitisation; Three Rs.

Indexed keywords

COSMETIC;

EID: 57349145721     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290803600511     Document Type: Article
Times cited : (23)

References (69)
  • 1
    • 57349153888 scopus 로고    scopus 로고
    • EU (2003). Directive 2003/15/EC of the European Parliament and of the Council of 27 February 2003 amending Council Directive 76/768/EEC on the approximation of the laws of the Member States relating to cosmetic products. Official Journal of the European Union L66, 26-35.
    • EU (2003). Directive 2003/15/EC of the European Parliament and of the Council of 27 February 2003 amending Council Directive 76/768/EEC on the approximation of the laws of the Member States relating to cosmetic products. Official Journal of the European Union L66, 26-35.
  • 5
    • 34247587012 scopus 로고    scopus 로고
    • Genetics. Getting closer to the whole picture
    • Sauer, U., Heinemann, M. & Zamboni, N. (2007). Genetics. Getting closer to the whole picture. Science 316, 550-551.
    • (2007) Science , vol.316 , pp. 550-551
    • Sauer, U.1    Heinemann, M.2    Zamboni, N.3
  • 6
    • 0037230506 scopus 로고    scopus 로고
    • An overall strategy for the testing of chemicals for human hazard and risk assessment under the EU REACH system
    • Combes, R., Barratt, M. & Balls, M. (2003). An overall strategy for the testing of chemicals for human hazard and risk assessment under the EU REACH system. ATLA 31, 7-19.
    • (2003) ATLA , vol.31 , pp. 7-19
    • Combes, R.1    Barratt, M.2    Balls, M.3
  • 8
    • 14644426625 scopus 로고    scopus 로고
    • The feasibility of replacing animal testing for assessing consumer safety: A suggested future direction
    • Fentem, J., Chamberlain, M. & Sangster, B. (2004). The feasibility of replacing animal testing for assessing consumer safety: a suggested future direction. ATLA 32, 617-623.
    • (2004) ATLA , vol.32 , pp. 617-623
    • Fentem, J.1    Chamberlain, M.2    Sangster, B.3
  • 10
    • 27644459086 scopus 로고    scopus 로고
    • Interactions of contact allergens with dendritic cells: Opportunities and challenges for the development of novel approaches to hazard assessment
    • Ryan, C.A., Gerberick, G.F., Gildea, L.A., Hulette, B.C., Betts, C.J., Cumberbatch, M., Dearman, R.J. & Kimber, I. (2005). Interactions of contact allergens with dendritic cells: opportunities and challenges for the development of novel approaches to hazard assessment. Toxicological Sciences 88, 4-11.
    • (2005) Toxicological Sciences , vol.88 , pp. 4-11
    • Ryan, C.A.1    Gerberick, G.F.2    Gildea, L.A.3    Hulette, B.C.4    Betts, C.J.5    Cumberbatch, M.6    Dearman, R.J.7    Kimber, I.8
  • 14
    • 57349182421 scopus 로고    scopus 로고
    • Novel Testing Strategies for In Vitro
    • The Sens-it-iv Consortium , 3pp. Available at:, Accessed 08.05.08
    • The Sens-it-iv Consortium (2006). Novel Testing Strategies for In Vitro Assessment of Allergens - Project Summary, 3pp. Available at: http://www.sens-it-iv.eu/index.php?id=800 (Accessed 08.05.08).
    • (2006) Assessment of Allergens - Project Summary
  • 16
    • 0036877375 scopus 로고    scopus 로고
    • A review of the scientific basis for uncertainty factors for use in quantitative risk assessment for the induction of allergic contact dermatitis
    • Felter, S.P., Robinson, M.K., Basketter, D.A. & Gerberick, G.F. (2002). A review of the scientific basis for uncertainty factors for use in quantitative risk assessment for the induction of allergic contact dermatitis. Contact Dermatitis 47, 257-266.
    • (2002) Contact Dermatitis , vol.47 , pp. 257-266
    • Felter, S.P.1    Robinson, M.K.2    Basketter, D.A.3    Gerberick, G.F.4
  • 20
    • 12344304313 scopus 로고    scopus 로고
    • Development and prevalidation of a list of structure-activity relationship rules to be used in expert systems for prediction of the skin-sensitising properties of chemicals
    • Gerner, I., Barratt, M.D., Zinke, S., Schlegel, K. & Schlede, E. (2004). Development and prevalidation of a list of structure-activity relationship rules to be used in expert systems for prediction of the skin-sensitising properties of chemicals. ATLA 32, 487-509.
    • (2004) ATLA , vol.32 , pp. 487-509
    • Gerner, I.1    Barratt, M.D.2    Zinke, S.3    Schlegel, K.4    Schlede, E.5
  • 21
    • 57349184021 scopus 로고    scopus 로고
    • Anon. (2004). OECD Principles for the Validation, for Regulatory Purposes, of (Quantitative) Structure- Activity Relationship Models, 2pp. Paris, France: OECD. Available at: http://www.oecd.org/document/23/0,2340,en- 2649-3436533957015-1-1-1-1,00.html (Accessed 10.10.08).
    • Anon. (2004). OECD Principles for the Validation, for Regulatory Purposes, of (Quantitative) Structure- Activity Relationship Models, 2pp. Paris, France: OECD. Available at: http://www.oecd.org/document/23/0,2340,en- 2649-3436533957015-1-1-1-1,00.html (Accessed 10.10.08).
  • 25
    • 0033028448 scopus 로고    scopus 로고
    • Skin sensitization risk assessment: A comparative evaluation of 3 isothiazolinone biocides
    • Basketter, D.A., Rodford, R., Kimber, I., Smith, I. & Wahlberg, J.E. (1999). Skin sensitization risk assessment: a comparative evaluation of 3 isothiazolinone biocides. Contact Dermatitis 40, 150-154.
    • (1999) Contact Dermatitis , vol.40 , pp. 150-154
    • Basketter, D.A.1    Rodford, R.2    Kimber, I.3    Smith, I.4    Wahlberg, J.E.5
  • 31
    • 57349189316 scopus 로고    scopus 로고
    • Further development of an in vitro skin absorption method to measure compartmental disposition and kinetics for chemicals in skin [Poster Abstract]
    • Pendlington, R., Minter, H., Stupart, L., MacKay, C., Roper, C., Sanders, D. & Pease, C. (2007). Further development of an in vitro skin absorption method to measure compartmental disposition and kinetics for chemicals in skin [Poster Abstract]. Toxicology Letters 172, S106.
    • (2007) Toxicology Letters , vol.172
    • Pendlington, R.1    Minter, H.2    Stupart, L.3    MacKay, C.4    Roper, C.5    Sanders, D.6    Pease, C.7
  • 35
    • 57349116822 scopus 로고    scopus 로고
    • Application of a systems biology approach for skin allergy risk assessment
    • Maxwell, G. & MacKay, C. (2008). Application of a systems biology approach for skin allergy risk assessment. AATEX 14 381-388.
    • (2008) AATEX , vol.14 , pp. 381-388
    • Maxwell, G.1    MacKay, C.2
  • 39
    • 44349084840 scopus 로고    scopus 로고
    • Chemical reactivity indices and mechanism-based read-across for non-animal based assessment of skin sensitisation potential
    • Roberts, D.W., Aptula, A.O., Patlewicz, G. & Pease, C. (2008). Chemical reactivity indices and mechanism-based read-across for non-animal based assessment of skin sensitisation potential. Journal of Applied Toxicology 28, 443-454.
    • (2008) Journal of Applied Toxicology , vol.28 , pp. 443-454
    • Roberts, D.W.1    Aptula, A.O.2    Patlewicz, G.3    Pease, C.4
  • 40
    • 57349172613 scopus 로고    scopus 로고
    • Reactivity assays for non-animal based prediction of skin sensitisation potential
    • Aptula, N., Roberts, D.W., Schultz, T.W. & Pease, C. (2007). Reactivity assays for non-animal based prediction of skin sensitisation potential. Toxicology 231, 117-118.
    • (2007) Toxicology , vol.231 , pp. 117-118
    • Aptula, N.1    Roberts, D.W.2    Schultz, T.W.3    Pease, C.4
  • 41
    • 57349086113 scopus 로고    scopus 로고
    • Hapten protein binding: From theory to practical application in the in vitro prediction of skin sensitisation
    • Divkovic, M., Pease, C.K., Gerberick, G.F. & Basketter, D.A. (2005). Hapten protein binding: from theory to practical application in the in vitro prediction of skin sensitisation. Contact Dermatitis 54, 73-74.
    • (2005) Contact Dermatitis , vol.54 , pp. 73-74
    • Divkovic, M.1    Pease, C.K.2    Gerberick, G.F.3    Basketter, D.A.4
  • 42
    • 84973718396 scopus 로고
    • Studies on the sensitization of animals with simple chemical compounds
    • Landsteiner, K. & Jacobs, J. (1935). Studies on the sensitization of animals with simple chemical compounds. The Journal of Experimental Medicine 61, 643-656.
    • (1935) The Journal of Experimental Medicine , vol.61 , pp. 643-656
    • Landsteiner, K.1    Jacobs, J.2
  • 43
    • 0345470677 scopus 로고    scopus 로고
    • Molecular aspects of allergic contact dermatitis
    • ed. R.J.G. Rycroft, T. Menne, P.J. Frosch, & J-P. Lepoittevin, pp, Berlin, Germany: Springer Verlag
    • Lepoittevin, J-P. (2001). Molecular aspects of allergic contact dermatitis. In Textbook of Contact Dermatitis. (ed. R.J.G. Rycroft, T. Menne, P.J. Frosch, & J-P. Lepoittevin), pp. 59-91. Berlin, Germany: Springer Verlag.
    • (2001) Textbook of Contact Dermatitis , pp. 59-91
    • Lepoittevin, J.-P.1
  • 44
  • 45
    • 35649009496 scopus 로고    scopus 로고
    • Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro
    • Natsch, A., Gfeller, H., Rothaupt, M. & Ellis, G. (2007). Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro. Toxicology in vitro 21, 1220-1226.
    • (2007) Toxicology in vitro , vol.21 , pp. 1220-1226
    • Natsch, A.1    Gfeller, H.2    Rothaupt, M.3    Ellis, G.4
  • 47
    • 24644446845 scopus 로고    scopus 로고
    • Structure-activity relationships for reactivity of carbonyl-containing compounds with glutathione
    • Schultz, T.W., Yarbrough, J.W. & Johnson, E.L. (2005). Structure-activity relationships for reactivity of carbonyl-containing compounds with glutathione. SAR & QSAR in Environmental Research 16, 313-322.
    • (2005) SAR & QSAR in Environmental Research , vol.16 , pp. 313-322
    • Schultz, T.W.1    Yarbrough, J.W.2    Johnson, E.L.3
  • 48
    • 27644552706 scopus 로고    scopus 로고
    • Cytokines and Langerhans cell mobilisation in mouse and man
    • Griffiths, C.E., Dearman, R.J., Cumberbatch, M. & Kimber, I. (2005). Cytokines and Langerhans cell mobilisation in mouse and man. Cytokine 32, 67-70.
    • (2005) Cytokine , vol.32 , pp. 67-70
    • Griffiths, C.E.1    Dearman, R.J.2    Cumberbatch, M.3    Kimber, I.4
  • 49
    • 24944474248 scopus 로고    scopus 로고
    • The EpiDerm test protocol for the upcoming ECVAM validation study on in vitro skin irritation tests - An assessment of the performance of the optimised test
    • Kandarova, H., Liebsch, M., Gerner, I., Schmidt, E., Genschow, E., Traue, D. & Spielmann, H. (2005). The EpiDerm test protocol for the upcoming ECVAM validation study on in vitro skin irritation tests - An assessment of the performance of the optimised test. ATLA 33, 351-367.
    • (2005) ATLA , vol.33 , pp. 351-367
    • Kandarova, H.1    Liebsch, M.2    Gerner, I.3    Schmidt, E.4    Genschow, E.5    Traue, D.6    Spielmann, H.7
  • 50
    • 24944481113 scopus 로고    scopus 로고
    • The in vitro acute skin irritation of chemicals: Optimisation of the EPISKIN prediction model within the framework of the ECVAM validation process
    • Cotovio, J., Grandidier, M.H., Portes, P., Roguet, R. & Rubinstenn, G. (2005). The in vitro acute skin irritation of chemicals: Optimisation of the EPISKIN prediction model within the framework of the ECVAM validation process. ATLA 33, 329-349.
    • (2005) ATLA , vol.33 , pp. 329-349
    • Cotovio, J.1    Grandidier, M.H.2    Portes, P.3    Roguet, R.4    Rubinstenn, G.5
  • 52
    • 57349165725 scopus 로고    scopus 로고
    • Development of a systems approach for the analysis of toxicogenomic data [Poster Abstract]
    • Warner, G.J., Adeleye, Y.A., Ideker, T., Workman, C.T. & Scott, D.J. (2007). Development of a systems approach for the analysis of toxicogenomic data [Poster Abstract]. Toxicology 231, 109-110.
    • (2007) Toxicology , vol.231 , pp. 109-110
    • Warner, G.J.1    Adeleye, Y.A.2    Ideker, T.3    Workman, C.T.4    Scott, D.J.5
  • 54
    • 33745450390 scopus 로고    scopus 로고
    • Development of an in vitro skin sensitization test using human cell lines: The human Cell Line Activation Test (h- CLAT). I: Optimization of the h-CLAT protocol
    • Ashikaga, T., Yoshida, Y., Hirota, M., Yoneyama, K., Itagaki, H., Sakaguchi, H., Miyazawa, M., Ito, Y., Suzuki, H. & Toyoda, H. (2006). Development of an in vitro skin sensitization test using human cell lines: the human Cell Line Activation Test (h- CLAT). I: Optimization of the h-CLAT protocol. Toxicology in vitro 20, 767-773.
    • (2006) Toxicology in vitro , vol.20 , pp. 767-773
    • Ashikaga, T.1    Yoshida, Y.2    Hirota, M.3    Yoneyama, K.4    Itagaki, H.5    Sakaguchi, H.6    Miyazawa, M.7    Ito, Y.8    Suzuki, H.9    Toyoda, H.10
  • 55
    • 33745468021 scopus 로고    scopus 로고
    • Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT). II: An inter-laboratory study of the h-CLAT
    • Sakaguchi, H., Ashikaga, T., Miyazawa, M., Yoshida, Y., Ito, Y., Yoneyama, K., Hirota, M., Itagaki, H., Toyoda, H. & Suzuki, H. (2006). Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT). II: An inter-laboratory study of the h-CLAT. Toxicology in vitro 20, 774-784.
    • (2006) Toxicology in vitro , vol.20 , pp. 774-784
    • Sakaguchi, H.1    Ashikaga, T.2    Miyazawa, M.3    Yoshida, Y.4    Ito, Y.5    Yoneyama, K.6    Hirota, M.7    Itagaki, H.8    Toyoda, H.9    Suzuki, H.10
  • 56
    • 33846407924 scopus 로고    scopus 로고
    • Prediction of preservative sensitization potential using surface marker CD86 and/or CD54 expression on human cell line, THP-1
    • Sakaguchi, H., Miyazawa, M., Yoshida, Y., Ito, Y. & Suzuki, H. (2007). Prediction of preservative sensitization potential using surface marker CD86 and/or CD54 expression on human cell line, THP-1. Archives of Dermatological Research 298, 427-437.
    • (2007) Archives of Dermatological Research , vol.298 , pp. 427-437
    • Sakaguchi, H.1    Miyazawa, M.2    Yoshida, Y.3    Ito, Y.4    Suzuki, H.5
  • 57
    • 33947719856 scopus 로고    scopus 로고
    • Assessment of the U937 cell line for the detection of contact allergens
    • Python, F., Goebel, C. & Aeby, P. (2007). Assessment of the U937 cell line for the detection of contact allergens. Toxicology & Applied Pharmacology 220, 113-124.
    • (2007) Toxicology & Applied Pharmacology , vol.220 , pp. 113-124
    • Python, F.1    Goebel, C.2    Aeby, P.3
  • 59
    • 0034616086 scopus 로고    scopus 로고
    • in vitro evaluation of the sensitization potential of weak contact allergens using Langerhans-like dendritic cells and autologous T cells
    • Rougier, N., Redziniak, G., Mougin, D., Schmitt, D. & Vincent, C. (2000). in vitro evaluation of the sensitization potential of weak contact allergens using Langerhans-like dendritic cells and autologous T cells. Toxicology 145, 73-82.
    • (2000) Toxicology , vol.145 , pp. 73-82
    • Rougier, N.1    Redziniak, G.2    Mougin, D.3    Schmitt, D.4    Vincent, C.5
  • 61
    • 0025197965 scopus 로고
    • Generation and characterization of T-helper cells by primary in vitro sensitization using Langerhans cells
    • Hauser, C. & Katz, S.I. (1990). Generation and characterization of T-helper cells by primary in vitro sensitization using Langerhans cells. Immunological Reviews 117, 67-84.
    • (1990) Immunological Reviews , vol.117 , pp. 67-84
    • Hauser, C.1    Katz, S.I.2
  • 63
    • 36749027674 scopus 로고    scopus 로고
    • Does irritation potency contribute to the skin sensitization potency of contact allergens?
    • Basketter, D.A., Kan-King-Yu, D., Dierkes, P. & Jowsey, I.R. (2007). Does irritation potency contribute to the skin sensitization potency of contact allergens? Cutaneous & Ocular Toxicology 26, 279-286.
    • (2007) Cutaneous & Ocular Toxicology , vol.26 , pp. 279-286
    • Basketter, D.A.1    Kan-King-Yu, D.2    Dierkes, P.3    Jowsey, I.R.4
  • 64
    • 34250675588 scopus 로고    scopus 로고
    • Proactive surveillance of contact allergies: An important component of the risk management strategy for skin sensitizers
    • Jowsey, I.R. (2007). Proactive surveillance of contact allergies: an important component of the risk management strategy for skin sensitizers. Contact Dermatitis 56, 305-310.
    • (2007) Contact Dermatitis , vol.56 , pp. 305-310
    • Jowsey, I.R.1
  • 65
    • 33847645894 scopus 로고    scopus 로고
    • The biocide polyhexamethylene biguanide remains an uncommon contact allergen
    • Schnuch, A., Geier, J., Uter, W., Basketter, D.A. & Jowsey, I.R. (2007). The biocide polyhexamethylene biguanide remains an uncommon contact allergen. Contact Dermatitis 56, 235-239.
    • (2007) Contact Dermatitis , vol.56 , pp. 235-239
    • Schnuch, A.1    Geier, J.2    Uter, W.3    Basketter, D.A.4    Jowsey, I.R.5
  • 66
    • 57349092356 scopus 로고    scopus 로고
    • Scientific Committee on Consumer Products (2007). Memorandum on Actual Status of Alternative Methods on the Use of Experimental Animals in the Safety Assessment of Cosmetic Ingredients in the European Union. SCCP/1111/07, 14pp. Brussels, Belgium: European Commission Health & Consumer Protection Directorate-General. Available at: ec.europa.eu/health/ph-risk/committees/04- sccp/docs/sccp-s-06.pdf (Accessed 12.09.08).
    • Scientific Committee on Consumer Products (2007). Memorandum on Actual Status of Alternative Methods on the Use of Experimental Animals in the Safety Assessment of Cosmetic Ingredients in the European Union. SCCP/1111/07, 14pp. Brussels, Belgium: European Commission Health & Consumer Protection Directorate-General. Available at: ec.europa.eu/health/ph-risk/committees/04- sccp/docs/sccp-s-06.pdf (Accessed 12.09.08).
  • 68
    • 0027062704 scopus 로고
    • Influence of area of application of allergen on sensitization in contact dermatitis
    • Upadhye, M.R. & Maibach, H.I. (1992). Influence of area of application of allergen on sensitization in contact dermatitis. Contact Dermatitis 27, 281-286.
    • (1992) Contact Dermatitis , vol.27 , pp. 281-286
    • Upadhye, M.R.1    Maibach, H.I.2


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