-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998;391:806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
2
-
-
0034676448
-
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
-
Gönczy P, Echeverri CJ, Oegema K, Coulson A, Jones SJ, Copley RR, Duperon J, Oegema J, Brehm M, Cassin E, Hannak E, Kirkham M, Pichler S, Flohrs K, Goessen A, Leidel S, Alleaume AM, Martin C, Ozlu N, Bork P, Hyman AA. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 2000;408:331-336.
-
(2000)
Nature
, vol.408
, pp. 331-336
-
-
Gönczy, P.1
Echeverri, C.J.2
Oegema, K.3
Coulson, A.4
Jones, S.J.5
Copley, R.R.6
Duperon, J.7
Oegema, J.8
Brehm, M.9
Cassin, E.10
Hannak, E.11
Kirkham, M.12
Pichler, S.13
Flohrs, K.14
Goessen, A.15
Leidel, S.16
Alleaume, A.M.17
Martin, C.18
Ozlu, N.19
Bork, P.20
Hyman, A.A.21
more..
-
3
-
-
15844431376
-
Full genome RNAi profiling of early embryogenesis in C. elegans
-
Sönnichsen B, Koski LB, Walsh A, Marshall P, Neumann B, Brehm M, Alleaume A-M, Artelt J, Bettencourt P, Cassin E, Hewitson M, Holz C, Khan M, Lazik S, Martin C, Nitschke B, Ruer M, Stamford J, Winzi M, Heinkel R, Röder M, Finell J, Häntsch H, Jones SJ, Jones M, Piano F, Gunsalus KC, Oegema K, Gönczy P, Coulson A, Hyman AA, Echeverri CJ. Full genome RNAi profiling of early embryogenesis in C. elegans. Nature 2005;434:462-469.
-
(2005)
Nature
, vol.434
, pp. 462-469
-
-
Sönnichsen, B.1
Koski, L.B.2
Walsh, A.3
Marshall, P.4
Neumann, B.5
Brehm, M.6
Alleaume, A.-M.7
Artelt, J.8
Bettencourt, P.9
Cassin, E.10
Hewitson, M.11
Holz, C.12
Khan, M.13
Lazik, S.14
Martin, C.15
Nitschke, B.16
Ruer, M.17
Stamford, J.18
Winzi, M.19
Heinkel, R.20
Röder, M.21
Finell, J.22
Häntsch, H.23
Jones, S.J.24
Jones, M.25
Piano, F.26
Gunsalus, K.C.27
Oegema, K.28
Gönczy, P.29
Coulson, A.30
Hyman, A.A.31
Echeverri, C.J.32
more..
-
4
-
-
0034676457
-
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
-
Fraser AG, Kamath RS, Zipperlen P, Martinez-Campos M, Sohrmann M, Ahringer J. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature 2000;408:325-330.
-
(2000)
Nature
, vol.408
, pp. 325-330
-
-
Fraser, A.G.1
Kamath, R.S.2
Zipperlen, P.3
Martinez-Campos, M.4
Sohrmann, M.5
Ahringer, J.6
-
5
-
-
0242361514
-
A functional genomic analysis of cell morphology using RNA interference
-
Kiger A, Baum B, Jones S, Jones M, Coulson A, Echeverri CJ, Perrimon N. A functional genomic analysis of cell morphology using RNA interference. Journal of Biology 2003;2:27.
-
(2003)
Journal of Biology
, vol.2
, pp. 27
-
-
Kiger, A.1
Baum, B.2
Jones, S.3
Jones, M.4
Coulson, A.5
Echeverri, C.J.6
Perrimon, N.7
-
6
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001;411:494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
7
-
-
33646187810
-
High-throughput RNAi screening in cultured cells: a user's guide
-
Echeverri CJ, Perrimon N. High-throughput RNAi screening in cultured cells: a user's guide. Nature Reviews Genetics 2006;7:373-384.
-
(2006)
Nature Reviews Genetics
, vol.7
, pp. 373-384
-
-
Echeverri, C.J.1
Perrimon, N.2
-
8
-
-
0037248879
-
Simultaneous detection of 15 human cytokines in a single sample of stimulated peripheral blood mononuclear cells
-
de Jager W, te Velthuis H, Prakken BJ, Kuis W, Rijkers GT. Simultaneous detection of 15 human cytokines in a single sample of stimulated peripheral blood mononuclear cells. Clinical and Diagnostic Laboratory Immunology 2003;10:133-139.
-
(2003)
Clinical and Diagnostic Laboratory Immunology
, vol.10
, pp. 133-139
-
-
de Jager, W.1
Te Velthuis, H.2
Prakken, B.J.3
Kuis, W.4
Rijkers, G.T.5
-
9
-
-
9144244290
-
Using RNAi to identify and validate novel drug targets-Targeting human kinases with an siRNA library
-
Krönke A, Grabner A, Hannus M, Sachse C, Dorris D, Echeverri C. Using RNAi to identify and validate novel drug targets-Targeting human kinases with an siRNA library. Drug Discovery World 2004;5:53-62.
-
(2004)
Drug Discovery World
, vol.5
, pp. 53-62
-
-
Krönke, A.1
Grabner, A.2
Hannus, M.3
Sachse, C.4
Dorris, D.5
Echeverri, C.6
-
10
-
-
21844440569
-
Genomewide analysis of human kinases in clathrin-and caveolae/raft-mediated endocytosis
-
Pelkmans L, Fava E, Grabner H, Hannus M, Habermann B, Krausz E, Zerial M. Genomewide analysis of human kinases in clathrin-and caveolae/raft-mediated endocytosis. Nature 2005;436:78-86.
-
(2005)
Nature
, vol.436
, pp. 78-86
-
-
Pelkmans, L.1
Fava, E.2
Grabner, H.3
Hannus, M.4
Habermann, B.5
Krausz, E.6
Zerial, M.7
-
11
-
-
20444426889
-
A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity
-
Kolfschoten IG, van Leeuwen B, Berns K, Mullenders J, Beijersbergen RL, Bernards R, Voorhoeve PM, Agami R. A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity. Cell 2005;121:849-858.
-
(2005)
Cell
, vol.121
, pp. 849-858
-
-
Kolfschoten, I.G.1
Van Leeuwen, B.2
Berns, K.3
Mullenders, J.4
Beijersbergen, R.L.5
Bernards, R.6
Voorhoeve, P.M.7
Agami, R.8
-
12
-
-
20444376939
-
A genetic screen for candidate tumor suppressors identifies REST
-
Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, Zhao JJ, Roberts TM, Mandel G, Hannon GJ, Depinho RA, Chin L, Elledge SJ. A genetic screen for candidate tumor suppressors identifies REST. Cell 2005;121:837-848.
-
(2005)
Cell
, vol.121
, pp. 837-848
-
-
Westbrook, T.F.1
Martin, E.S.2
Schlabach, M.R.3
Leng, Y.4
Liang, A.C.5
Feng, B.6
Zhao, J.J.7
Roberts, T.M.8
Mandel, G.9
Hannon, G.J.10
Depinho, R.A.11
Chin, L.12
Elledge, S.J.13
-
13
-
-
19944430064
-
High throughput RNA interference strategies for target discovery and validation by using synthetic short interfering RNAs: functional genomics investigations of biological pathways
-
Sachse C, Krausz E, Krönke A, Hannus M, Grabner A,Walsh A, Ovcharenko D, Dorris D, Trudel C, Sönnichsen B, Echeverri CJ. High throughput RNA interference strategies for target discovery and validation by using synthetic short interfering RNAs: functional genomics investigations of biological pathways. Methods in Enzymology 2005;392:242-277.
-
(2005)
Methods in Enzymology
, vol.392
, pp. 242-277
-
-
Sachse, C.1
Krausz, E.2
Krönke, A.3
Hannus, M.4
Grabner, A.5
Walsh, A.6
Ovcharenko, D.7
Dorris, D.8
Trudel, C.9
Sönnichsen, B.10
Echeverri, C.J.11
-
14
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS. Expression profiling reveals off-target gene regulation by RNAi. Nature Biotechnology 2003;21:635-637.
-
(2003)
Nature Biotechnology
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
15
-
-
33745612464
-
Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity
-
Jackson AL, Burchard J, Schelter J, Chau BN, Cleary M, Lim L, Linsley PS. Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity. RNA 2006;12:1179-1187.
-
(2006)
RNA
, vol.12
, pp. 1179-1187
-
-
Jackson, A.L.1
Burchard, J.2
Schelter, J.3
Chau, B.N.4
Cleary, M.5
Lim, L.6
Linsley, P.S.7
-
16
-
-
33749023011
-
Minimizing the risk of reporting false positives in large-scale RNAi screens
-
Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, Ma Y, Mathey-Prevot B, Root DE, Sabatini DM, Taipale J, Perrimon N, Bernards R. Minimizing the risk of reporting false positives in large-scale RNAi screens. Nature Methods 2006;3:777-779.
-
(2006)
Nature Methods
, vol.3
, pp. 777-779
-
-
Echeverri, C.J.1
Beachy, P.A.2
Baum, B.3
Boutros, M.4
Buchholz, F.5
Chanda, S.K.6
Downward, J.7
Ellenberg, J.8
Fraser, A.G.9
Hacohen, N.10
Hahn, W.C.11
Jackson, A.L.12
Kiger, A.13
Linsley, P.S.14
Lum, L.15
Ma, Y.16
Mathey-Prevot, B.17
Root, D.E.18
Sabatini, D.M.19
Taipale, J.20
Perrimon, N.21
Bernards, R.22
more..
-
17
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, Gotta M, Kanapin A, Le Bot N, Moreno S, Sohrmann M, Welchman DP, Zipperlen P, Ahringer J. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 2003;421:231-237.
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
Fraser, A.G.2
Dong, Y.3
Poulin, G.4
Durbin, R.5
Gotta, M.6
Kanapin, A.7
Le Bot, N.8
Moreno, S.9
Sohrmann, M.10
Welchman, D.P.11
Zipperlen, P.12
Ahringer, J.13
-
18
-
-
33646057010
-
Highthroughput RNAi screening by time-lapse imaging of live human cells
-
Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J. Highthroughput RNAi screening by time-lapse imaging of live human cells. Nature Methods 2006;3:385-390.
-
(2006)
Nature Methods
, vol.3
, pp. 385-390
-
-
Neumann, B.1
Held, M.2
Liebel, U.3
Erfle, H.4
Rogers, P.5
Pepperkok, R.6
Ellenberg, J.7
-
19
-
-
34547358822
-
Tumor stroma fosters neovascularization by recruitment of progenitor cells into the tumor bed
-
Ganss R. Tumor stroma fosters neovascularization by recruitment of progenitor cells into the tumor bed. Journal of Cellular and Molecular Medicine 2006;10:857-865.
-
(2006)
Journal of Cellular and Molecular Medicine
, vol.10
, pp. 857-865
-
-
Ganss, R.1
-
21
-
-
0037112508
-
Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation
-
Peng Y, Zhang Q, Nagasawa H, Okayasu R, Liber HL, Bedford JS. Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation. Cancer Research 2002;62:6400-6404.
-
(2002)
Cancer Research
, vol.62
, pp. 6400-6404
-
-
Peng, Y.1
Zhang, Q.2
Nagasawa, H.3
Okayasu, R.4
Liber, H.L.5
Bedford, J.S.6
-
22
-
-
23044502867
-
Chemotherapy compounds in cervical cancer cells primed by reconstitution of pp53 function after short interfering RNA-mediated degradation of human papillomavirus 18 E6 mRNA: opposite effect of siRNA in combination with different drugs
-
Koivusalo R, Krausz E, Helenius H, Hietanen S. Chemotherapy compounds in cervical cancer cells primed by reconstitution of pp53 function after short interfering RNA-mediated degradation of human papillomavirus 18 E6 mRNA: opposite effect of siRNA in combination with different drugs. Molecular Pharmacology 2005;68:372-382.
-
(2005)
Molecular Pharmacology
, vol.68
, pp. 372-382
-
-
Koivusalo, R.1
Krausz, E.2
Helenius, H.3
Hietanen, S.4
-
23
-
-
33644752656
-
RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors
-
Morgan-Lappe S, Woods KW, Li Q, Anderson MG, Schurdak ME, Luo Y, Giranda VL, Fesik SW, Leverson JD. RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors. Oncogene 2006;25:1340-1348.
-
(2006)
Oncogene
, vol.25
, pp. 1340-1348
-
-
Morgan-Lappe, S.1
Woods, K.W.2
Li, Q.3
Anderson, M.G.4
Schurdak, M.E.5
Luo, Y.6
Giranda, V.L.7
Fesik, S.W.8
Leverson, J.D.9
-
24
-
-
33645813378
-
Mass spectrometry and protein analysis
-
Domon B,Aebersold R.Mass spectrometry and protein analysis. Science 2006;312:212-217.
-
(2006)
Science
, vol.312
, pp. 212-217
-
-
Domon, B.1
Aebersold, R.2
-
25
-
-
33746616420
-
In-depth analysis of the membrane and cytosolic proteome of red blood cells
-
Pasini EM, Kirkegaard M, Mortensen P, Lutz HU, Thomas AW, Mann M. In-depth analysis of the membrane and cytosolic proteome of red blood cells. Blood 2006;108:791-801.
-
(2006)
Blood
, vol.108
, pp. 791-801
-
-
Pasini, E.M.1
Kirkegaard, M.2
Mortensen, P.3
Lutz, H.U.4
Thomas, A.W.5
Mann, M.6
-
26
-
-
0037435030
-
Mass spectrometry-based proteomics
-
Aebersold R, Mann M. Mass spectrometry-based proteomics. Nature 2003;422:198-207.
-
(2003)
Nature
, vol.422
, pp. 198-207
-
-
Aebersold, R.1
Mann, M.2
-
28
-
-
33751057231
-
Chemical genetic strategies to delineate MAP kinase signaling pathways using protein-fragment complementation assays (PCA)
-
Michnick SW, Macdonald ML, Westwick JK. Chemical genetic strategies to delineate MAP kinase signaling pathways using protein-fragment complementation assays (PCA). Methods 2006;40:287-293.
-
(2006)
Methods
, vol.40
, pp. 287-293
-
-
Michnick, S.W.1
Macdonald, M.L.2
Westwick, J.K.3
|