메뉴 건너뛰기




Volumn 114, Issue 6, 2011, Pages 1403-1416

A peripheral adrenoceptor-mediated sympathetic mechanism can transform stress-induced analgesia into hyperalgesia

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CORTISONE; GUANETHIDINE; IDAZOXAN; N METHYL DEXTRO ASPARTIC ACID; PRAZOSIN; RAUWOLSCINE; SULPROSTONE;

EID: 79958105796     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e31821c3878     Document Type: Conference Paper
Times cited : (45)

References (56)
  • 1
    • 0023046987 scopus 로고
    • Noradrenaline hyperalgesia is mediated through interaction with sympathetic postganglionic neurone terminals rather than activation of primary afferent nociceptors
    • Levine JD, Taiwo YO, Collins SD, Tam JK: Noradrenaline hyperalgesia is mediated through interaction with sympathetic postganglionic neurone terminals rather than activation of primary afferent nociceptors. Nature 1986; 323:158-60. (Pubitemid 16024962)
    • (1986) Nature , vol.322 , Issue.6084 , pp. 158-160
    • Levine, J.D.1    Taiwo, Y.O.2    Collins, S.D.3
  • 2
    • 0023606146 scopus 로고
    • Activation of unmyelinated afferents in chronically lesioned nerves by adrenaline and excitation of sympathetic efferents in the cat
    • DOI 10.1016/0304-3940(87)90167-4
    • Häbler HJ, Jänig W, Koltzenburg M: Activation of unmyelinated afferents in chronically lesioned nerves by adrenaline and excitation of sympathetic efferents in the cat. Neurosci Lett 1987; 82:35-40. (Pubitemid 18049538)
    • (1987) Neuroscience Letters , vol.82 , Issue.1 , pp. 35-40
    • Habler, H.-J.1    Janig, W.2    Koltzenburg, M.3
  • 3
    • 0024381079 scopus 로고
    • Sympathetic facilitation of sustained discharges of polymodal nociceptors
    • Hu SJ, Zhu J: Sympathetic facilitation of sustained discharges of polymodal nociceptors. Pain 1989; 38:85-90.
    • (1989) Pain , vol.38 , pp. 85-90
    • Hu, S.J.1    Zhu, J.2
  • 4
    • 0025828784 scopus 로고
    • Adrenergic excitation of cutaneous pain receptors induced by peripheral nerve injury
    • Sato J, Perl ER: Adrenergic excitation of cutaneous pain receptors induced by peripheral nerve injury. Science 1991; 251:1608-10.
    • (1991) Science , vol.251 , pp. 1608-1611
    • Sato, J.1    Perl, E.R.2
  • 5
    • 0034175743 scopus 로고    scopus 로고
    • The α(2A) adrenoceptor and the sympathetic postganglionic neuron contribute to the development of neuropathic heat hyperalgesia in mice
    • DOI 10.1016/S0304-3959(99)00286-9, PII S0304395999002869
    • Kingery WS, Guo TZ, Davies MF, Limbird L, Maze M: The alpha(2A) adrenoceptor and the sympathetic postganglionic neuron contribute to the development of neuropathic heat hyperalgesia in mice. Pain 2000; 85:345-58. (Pubitemid 30214162)
    • (2000) Pain , vol.85 , Issue.3 , pp. 345-358
    • Kingery, W.S.1    Guo, T.Z.2    Davies, M.F.3    Limbird, L.4    Maze, M.5
  • 6
    • 0033105552 scopus 로고    scopus 로고
    • 2-adrenergic receptors in rat primary afferent neurones after peripheral nerve injury or inflammation
    • Birder LA, Perl ER: Expression of alpha2-adrenergic receptors in rat primary afferent neurones after peripheral nerve injury or inflammation. J Physiol 1999; 515(Pt 2):533-42. (Pubitemid 29129223)
    • (1999) Journal of Physiology , vol.515 , Issue.2 , pp. 533-542
    • Birder, L.A.1    Perl, E.R.2
  • 7
    • 0037322559 scopus 로고    scopus 로고
    • Sympathetic modulation of acute cutaneous flare induced by intradermal injection of capsaicin in anesthetized rats
    • DOI 10.1152/jn.00568.2002
    • Lin Q, Zou X, Fang L, Willis WD: Sympathetic modulation of acute cutaneous flare induced by intradermal injection of capsaicin in anesthetized rats. J Neurophysiol 2003; 89:853-61. (Pubitemid 36206134)
    • (2003) Journal of Neurophysiology , vol.89 , Issue.2 , pp. 853-861
    • Lin, Q.1    Zou, X.2    Fang, L.3    Willis, W.D.4
  • 8
    • 0025836870 scopus 로고
    • Systemic alphaadrenergic blockade with phentolamine: A diagnostic test for sympathetically maintained pain
    • Raja SN, Treede RD, Davis KD, Campbell JN: Systemic alphaadrenergic blockade with phentolamine: A diagnostic test for sympathetically maintained pain. ANESTHESIOLOGY 1991; 74: 691-8.
    • (1991) ANESTHESIOLOGY , vol.74 , pp. 691-698
    • Raja, S.N.1    Treede, R.D.2    Davis, K.D.3    Campbell, J.N.4
  • 10
    • 0019308323 scopus 로고
    • Opioid and nonopioid mechanisms of stress analgesia
    • Lewis JW, Cannon JT, Liebeskind JC: Opioid and nonopioid mechanisms of stress analgesia. Science 1980; 208:623-5. (Pubitemid 10041984)
    • (1980) Science , vol.208 , Issue.4444 , pp. 623-625
    • Lewis, J.W.1    Cannon, J.T.2    Liebeskind, J.C.3
  • 11
    • 0019967165 scopus 로고
    • Organization of endogenous opiate and nonopiate pain control systems
    • Watkins LR, Mayer DJ: Organization of endogenous opiate and nonopiate pain control systems. Science 1982; 216:1185-92.
    • (1982) Science , vol.216 , pp. 1185-1199
    • Watkins, L.R.1    Mayer, D.J.2
  • 12
    • 0031760762 scopus 로고    scopus 로고
    • Midbrain periaqueductal gray (PAG) inhibits nociceptive inputs to sacral dorsal horn nociceptive neurons through alpha2-adrenergic receptors
    • Budai D, Harasawa I, Fields HL: Midbrain periaqueductal gray (PAG) inhibits nociceptive inputs to sacral dorsal horn nociceptive neurons through alpha2-adrenergic receptors. J Neurophysiol 1998; 80:2244-54.
    • (1998) J Neurophysiol , vol.80 , pp. 2244-2255
    • Budai, D.1    Harasawa, I.2    Fields, H.L.3
  • 14
    • 0033547241 scopus 로고    scopus 로고
    • Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission
    • Hein L, Altman JD, Kobilka BK: Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission. Nature 1999; 402:181-4.
    • (1999) Nature , vol.402 , pp. 181-184
    • Hein, L.1    Altman, J.D.2    Kobilka, B.K.3
  • 15
    • 0025787684 scopus 로고
    • Topical application of clonidine relieves hyperalgesia in patients with sympathetically maintained pain
    • Davis KD, Treede RD, Raja SN, Meyer RA, Campbell JN: Topical application of clonidine relieves hyperalgesia in patients with sympathetically maintained pain. Pain 1991; 47:309-17.
    • (1991) Pain , vol.47 , pp. 309-317
    • Davis, K.D.1    Treede, R.D.2    Raja, S.N.3    Meyer, R.A.4    Campbell, J.N.5
  • 16
    • 0032129192 scopus 로고    scopus 로고
    • Differential distribution of alpha2A and alpha2Cadrenergic receptor immunoreactivity in the rat spinal cord
    • Stone LS, Broberger C, Vulchanova L, Wilcox GL, Hökfelt T, Riedl MS, Elde R: Differential distribution of alpha2A and alpha2Cadrenergic receptor immunoreactivity in the rat spinal cord. J Neurosci 1998; 18:5928-37.
    • (1998) J Neurosci , vol.18 , pp. 5928-5933
    • Stone, L.S.1    Broberger, C.2    Vulchanova, L.3    Wilcox, G.L.4    Hökfelt, T.5    Riedl, M.S.6    Elde, R.7
  • 17
    • 0029824374 scopus 로고    scopus 로고
    • Distribution of α(2A)-adrenergic receptor-like immunoreactivity in the rat central nervous system
    • DOI 10.1002/(SICI)1096-9861(19960812)372:1<111::AID-CNE8>3.0.CO;2-6
    • Talley EM, Rosin DL, Lee A, Guyenet PG, Lynch KR: Distribution of alpha 2A-adrenergic receptor-like immunoreactivity in the rat central nervous system. J Comp Neurol 1996; 372:111-34. (Pubitemid 26286712)
    • (1996) Journal of Comparative Neurology , vol.372 , Issue.1 , pp. 111-134
    • Talley, E.M.1    Rosin, D.L.2    Lee, A.3    Guyenet, P.G.4    Lynch, K.R.5
  • 18
    • 0029847017 scopus 로고    scopus 로고
    • Distribution of α(2C)-adrenergic receptor-like immunoreactivity in the rat central nervous system
    • DOI 10.1002/(SICI)1096-9861(19960812)372:1<135::AID-CNE9>3.3.CO;2-B
    • Rosin DL, Talley EM, Lee A, Stornetta RL, Gaylinn BD, Guyenet PG, Lynch KR: Distribution of alpha 2C-adrenergic receptor-like immunoreactivity in the rat central nervous system. J Comp Neurol 1996; 372:135-65. (Pubitemid 26286713)
    • (1996) Journal of Comparative Neurology , vol.372 , Issue.1 , pp. 135-165
    • Rosin, D.L.1    Talley, E.M.2    Lee, A.3    Stornetta, R.L.4    Gaylinn, B.D.5    Guyenet, P.G.6    Lynch, K.R.7
  • 19
    • 54549090855 scopus 로고    scopus 로고
    • Alpha(2)-noradrenergic antagonist administration into the central nucleus of the amygdala blocks stress-induced hypoalgesia in awake behaving rats
    • Ortiz JP, Close LN, Heinricher MM, Selden NR: Alpha(2)-noradrenergic antagonist administration into the central nucleus of the amygdala blocks stress-induced hypoalgesia in awake behaving rats. Neuroscience 2008; 157:223-8.
    • (2008) Neuroscience , vol.157 , pp. 223-228
    • Ortiz, J.P.1    Close, L.N.2    Heinricher, M.M.3    Selden, N.R.4
  • 20
    • 0030610424 scopus 로고    scopus 로고
    • Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo
    • Lakhlani PP, MacMillan LB, Guo TZ, McCool BA, Lovinger DM, Maze M, Limbird LE: Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo. Proc Natl Acad Sci USA 1997; 94:9950-5.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9950-9955
    • Lakhlani, P.P.1    MacMillan, L.B.2    Guo, T.Z.3    McCool, B.A.4    Lovinger, D.M.5    Maze, M.6    Limbird, L.E.7
  • 22
    • 0030611098 scopus 로고    scopus 로고
    • The alpha2a adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy
    • Stone LS, MacMillan LB, Kitto KF, Limbird LE, Wilcox GL: The alpha2a adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy. J Neurosci 1997; 17:7157-65.
    • (1997) J Neurosci , vol.17 , pp. 7157-7166
    • Stone, L.S.1    MacMillan, L.B.2    Kitto, K.F.3    Limbird, L.E.4    Wilcox, G.L.5
  • 23
    • 3042551691 scopus 로고    scopus 로고
    • 2A adrenoceptors contribute to feedback inhibition of capsaicin-induced hyperalgesia
    • DOI 10.1097/00000542-200407000-00029
    • Mansikka H, Lähdesmäki J, Scheinin M, Pertovaara A: Alpha(2A) adrenoceptors contribute to feedback inhibition of capsaicin-induced hyperalgesia. ANESTHESIOLOGY 2004; 101:185-90. (Pubitemid 38833281)
    • (2004) Anesthesiology , vol.101 , Issue.1 , pp. 185-190
    • Mansikka, H.1    Lahdesmaki, J.2    Scheinin, M.3    Pertovaara, A.4
  • 24
    • 0031015517 scopus 로고    scopus 로고
    • Neurocircuitry of stress: Central control of the hypothalamo-pituitary- adrenocortical axis
    • DOI 10.1016/S0166-2236(96)10069-2, PII S0166223696100692
    • Herman JP, Cullinan WE: Neurocircuitry of stress: Central control of the hypothalamo-pituitary-adrenocortical axis. Trends Neurosci 1997; 20:78-84. (Pubitemid 27050702)
    • (1997) Trends in Neurosciences , vol.20 , Issue.2 , pp. 78-84
    • Herman, J.P.1    Cullinan, W.E.2
  • 25
    • 0037295238 scopus 로고    scopus 로고
    • Repeated, non-habituating stress suppresses inflammatory plasma extravasation by a novel, sympathoadrenal dependent mechanism
    • DOI 10.1046/j.1460-9568.2003.02493.x
    • Strausbaugh HJ, Green PG, Dallman MF, Levine JD: Repeated, non-habituating stress suppresses inflammatory plasma extravasation by a novel, sympathoadrenal dependent mechanism. Eur J Neurosci 2003; 17:805-12. (Pubitemid 36315250)
    • (2003) European Journal of Neuroscience , vol.17 , Issue.4 , pp. 805-812
    • Strausbaugh, H.J.1    Green, P.G.2    Dallman, M.F.3    Levine, J.D.4
  • 26
    • 20444502435 scopus 로고    scopus 로고
    • Repeated sound stress enhances inflammatory pain in the rat
    • DOI 10.1016/j.pain.2005.03.040, PII S0304395905001600
    • Khasar SG, Green PG, Levine JD: Repeated sound stress enhances inflammatory pain in the rat. Pain 2005; 116:79-86. (Pubitemid 40828503)
    • (2005) Pain , vol.116 , Issue.1-2 , pp. 79-86
    • Khasar, S.G.1    Green, P.G.2    Levine, J.D.3
  • 27
    • 0022262681 scopus 로고
    • Non-opiate analgesia following stressful acoustic stimulation
    • DOI 10.1016/0031-9384(85)90185-4
    • Szikszay M, Benedek G, Hideg J: Non-opiate analgesia following stressful acoustic stimulation. Physiol Behav 1985; 35: 135-8. (Pubitemid 15018742)
    • (1985) Physiology and Behavior , vol.35 , Issue.1 , pp. 135-138
    • Szikszay, M.1    Benedik, G.2    Hideg, J.3
  • 28
    • 0021687704 scopus 로고
    • Intrinsic mechanisms of pain inhibition: Activation by stress
    • Terman GW, Shavit Y, Lewis JW, Cannon JT, Liebeskind JC: Intrinsic mechanisms of pain inhibition: Activation by stress. Science 1984; 226:1270-7. (Pubitemid 15215581)
    • (1984) Science , vol.226 , Issue.4680 , pp. 1270-1277
    • Terman, G.W.1    Shavit, Y.2    Lewis, J.W.3
  • 29
    • 0018956018 scopus 로고
    • Intrathecal morphine in mice: A new technique
    • DOI 10.1016/0014-2999(80)90515-4
    • Hylden JL, Wilcox GL: Intrathecal morphine in mice: A new technique. Eur J Pharmacol 1980; 67:313-6. (Pubitemid 10007057)
    • (1980) European Journal of Pharmacology , vol.67 , Issue.2-3 , pp. 313-316
    • Hylden, J.L.K.1    Wilcox, G.L.2
  • 30
    • 39449126275 scopus 로고    scopus 로고
    • Transient allodynia pain models in mice for early assessment of analgesic activity
    • DOI 10.1038/sj.bjp.0707412, PII 0707412
    • Gil DW, Cheevers CV, Donello JE: Transient allodynia pain models in mice for early assessment of analgesic activity. Br J Pharmacol 2008; 153:769-74. (Pubitemid 351271749)
    • (2008) British Journal of Pharmacology , vol.153 , Issue.4 , pp. 769-774
    • Gil, D.W.1    Cheevers, C.V.2    Donello, J.E.3
  • 31
    • 33646455347 scopus 로고    scopus 로고
    • Windup in dorsal horn neurons is modulated by endogenous spinal μ-opioid mechanisms
    • DOI 10.1523/JNEUROSCI.0960-06.2006
    • Guan Y, Borzan J, Meyer RA, Raja SN: Windup in dorsal horn neurons is modulated by endogenous spinal mu-opioid mechanisms. J Neurosci 2006; 26:4298-307. (Pubitemid 44315389)
    • (2006) Journal of Neuroscience , vol.26 , Issue.16 , pp. 4298-4307
    • Guan, Y.1    Borzan, J.2    Meyer, R.A.3    Raja, S.N.4
  • 33
    • 8644274638 scopus 로고    scopus 로고
    • Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation
    • Nackley AG, Zvonok AM, Makriyannis A, Hohmann AG: Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation. J Neurophysiol 2004; 92:3562-74.
    • (2004) J Neurophysiol , vol.92 , pp. 3562-3577
    • Nackley, A.G.1    Zvonok, A.M.2    Makriyannis, A.3    Hohmann, A.G.4
  • 35
    • 0042421942 scopus 로고    scopus 로고
    • Anesthetics inhibit high-affinity states of dopamine D2 and other G-linked receptors
    • DOI 10.1002/syn.10221
    • Seeman P, Kapur S: Anesthetics inhibit high-affinity states of dopamine D2 and other G-linked receptors. Synapse 2003; 50:35-40. (Pubitemid 37034111)
    • (2003) Synapse , vol.50 , Issue.1 , pp. 35-40
    • Seeman, P.1    Kapur, S.2
  • 36
    • 0035878076 scopus 로고    scopus 로고
    • PKCγ contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain
    • Martin WJ, Malmberg AB, Basbaum AI: PKCgamma contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain. J Neurosci 2001; 21:5321-7. (Pubitemid 32622958)
    • (2001) Journal of Neuroscience , vol.21 , Issue.14 , pp. 5321-5327
    • Martin, W.J.1    Malmberg, A.B.2    Basbaum, A.I.3
  • 37
    • 0034988626 scopus 로고    scopus 로고
    • Sensory processing in the deep spinal dorsal horn of neurokinin-1 receptor knockout mice
    • Weng HR, Mansikka H, Winchurch R, Raja SN, Dougherty PM: Sensory processing in the deep spinal dorsal horn of neurokinin-1 receptor knockout mice. ANESTHESIOLOGY 2001; 94:1105-12.
    • (2001) ANESTHESIOLOGY , vol.94 , pp. 1105-1111
    • Weng, H.R.1    Mansikka, H.2    Winchurch, R.3    Raja, S.N.4    Dougherty, P.M.5
  • 38
    • 0242543184 scopus 로고    scopus 로고
    • The coding of noxious mechanical and thermal stimuli of deep dorsal horn neurones is attenuated in NK1 knockout mice
    • DOI 10.1016/S0028-3908(03)00281-8
    • Suzuki R, Hunt SP, Dickenson AH: The coding of noxious mechanical and thermal stimuli of deep dorsal horn neurones is attenuated in NK1 knockout mice. Neuropharmacology 2003; 45:1093-100. (Pubitemid 37412254)
    • (2003) Neuropharmacology , vol.45 , Issue.8 , pp. 1093-1100
    • Suzuki, R.1    Hunt, S.P.2    Dickenson, A.H.3
  • 39
    • 0022508683 scopus 로고
    • Wide-dynamic-range dorsal horn neurons participate in the encoding process by which monkeys perceive the intensity of noxious heat stimuli
    • DOI 10.1016/0006-8993(86)90435-X
    • Maixner W, Dubner R, Bushnell MC, Kenshalo DR Jr, Oliveras JL: Wide-dynamic-range dorsal horn neurons participate in the encoding process by which monkeys perceive the intensity of noxious heat stimuli. Brain Res 1986; 374:385-8. (Pubitemid 16077992)
    • (1986) Brain Research , vol.374 , Issue.2 , pp. 385-388
    • Maixner, W.1    Dubner, R.2    Bushnell, M.C.3
  • 40
    • 0023807073 scopus 로고
    • Dorsal horn neurophysiology of pain
    • Willis WD Jr: Dorsal horn neurophysiology of pain. Ann N Y Acad Sci 1988; 531:76-89.
    • (1988) Ann N y Acad Sci , vol.531 , pp. 76-89
    • Willis Jr., W.D.1
  • 41
    • 0021072543 scopus 로고
    • Activity evoked by A-and C-afferent fibers in rat dorsal horn neurons and its relation to a flexion reflex
    • Schouenborg J, Sjölund BH: Activity evoked by A-and C-afferent fibers in rat dorsal horn neurons and its relation to a flexion reflex. J Neurophysiol 1983; 50:1108-21.
    • (1983) J Neurophysiol , vol.50 , pp. 1108-1122
    • Schouenborg, J.1    Sjölund, B.H.2
  • 42
    • 0032945956 scopus 로고    scopus 로고
    • Windup leads to characteristics of central sensitization
    • DOI 10.1016/S0304-3959(98)00154-7, PII S0304395998001547
    • Li J, Simone DA, Larson AA: Windup leads to characteristics of central sensitization. Pain 1999; 79:75-82. (Pubitemid 29012438)
    • (1999) Pain , vol.79 , Issue.1 , pp. 75-82
    • Li, J.1    Simone, D.A.2    Larson, A.A.3
  • 43
    • 33845341118 scopus 로고    scopus 로고
    • Locus coeruleus activation by foot shock or electrical stimulation inhibits amygdala neurons
    • DOI 10.1016/j.neuroscience.2006.09.037, PII S0306452206013017
    • Chen FJ, Sara SJ: Locus coeruleus activation by foot shock or electrical stimulation inhibits amygdala neurons. Neuroscience 2007; 144:472-81. (Pubitemid 44873044)
    • (2007) Neuroscience , vol.144 , Issue.2 , pp. 472-481
    • Chen, F.-J.1    Sara, S.J.2
  • 44
    • 0028275763 scopus 로고
    • A novel long-latency response of locus coeruleus neurons to noxious stimuli: Mediation by peripheral C-fibers
    • Hirata H, Aston-Jones G: A novel long-latency response of locus coeruleus neurons to noxious stimuli: Mediation by peripheral C-fibers. J Neurophysiol 1994; 71:1752-61.
    • (1994) J Neurophysiol , vol.71 , pp. 1752-1766
    • Hirata, H.1    Aston-Jones, G.2
  • 45
    • 61549128656 scopus 로고    scopus 로고
    • 1-adrenergic receptor agonist activity of clinical-adrenergic receptor agonists interferes with-2-mediated analgesia
    • Gil DW, Cheevers CV, Kedzie KM, Manlapaz CA, Rao S, Tang E, Donello JE: 1-adrenergic receptor agonist activity of clinical-adrenergic receptor agonists interferes with-2-mediated analgesia. ANESTHESIOLOGY 2009; 110:401-7.
    • (2009) ANESTHESIOLOGY , vol.110 , pp. 401-407
    • Gil, D.W.1    Cheevers, C.V.2    Kedzie, K.M.3    Manlapaz, C.A.4    Rao, S.5    Tang, E.6    Donello, J.E.7
  • 47
    • 0020028017 scopus 로고
    • Footshock induced analgesia is dependent neither on pituitary nor sympathetic activation
    • DOI 10.1016/0006-8993(82)90341-9
    • Watkins LR, Cobelli DA, Newsome HH, Mayer DJ: Footshock induced analgesia is dependent neither on pituitary nor sympathetic activation. Brain Res 1982; 245:81-96. (Pubitemid 12099312)
    • (1982) Brain Research , vol.245 , Issue.1 , pp. 81-96
    • Watkins, L.R.1    Cobelli, D.A.2    Newsome, H.H.3    Mayer, D.J.4
  • 48
    • 0033954634 scopus 로고    scopus 로고
    • Wind-up of spinal cord neurones and pain sensation: Much ado about something?
    • DOI 10.1016/S0301-0082(99)00051-9, PII S0301008299000519
    • Herrero JF, Laird JM, López-García JA: Wind-up of spinal cord neurones and pain sensation: Much ado about something? Prog Neurobiol 2000; 61:169-203. (Pubitemid 30110477)
    • (2000) Progress in Neurobiology , vol.61 , Issue.2 , pp. 169-203
    • Herrero, J.F.1    Laird, J.M.A.2    Lopez-Garcia, J.A.3
  • 49
    • 0035038030 scopus 로고    scopus 로고
    • Contribution of alpha(2) receptor subtypes to nerve injuryinduced pain and its regulation by dexmedetomidine
    • Malmberg AB, Hedley LR, Jasper JR, Hunter JC, Basbaum AI: Contribution of alpha(2) receptor subtypes to nerve injuryinduced pain and its regulation by dexmedetomidine. Br J Pharmacol 2001; 132:1827-36.
    • (2001) Br J Pharmacol , Issue.132 , pp. 1827-1833
    • Malmberg, A.B.1    Hedley, L.R.2    Jasper, J.R.3    Hunter, J.C.4    Basbaum, A.I.5
  • 50
    • 0032522922 scopus 로고    scopus 로고
    • Vagotomy-induced enhancement of mechanical hyperalgesia in the rat is sympathoadrenal-mediated
    • Khasar SG, Miao FJ, Jänig W, Levine JD: Vagotomy-induced enhancement of mechanical hyperalgesia in the rat is sympathoadrenal-mediated. J Neurosci 1998; 18:3043-9. (Pubitemid 28163234)
    • (1998) Journal of Neuroscience , vol.18 , Issue.8 , pp. 3043-3049
    • Khasar, S.G.1    Miao, F.J.-P.2    Janig, W.3    Levine, J.D.4
  • 51
    • 0024450087 scopus 로고
    • Sympathetic and noradrenaline effects on C-fibre transmission: Single-unit analysis
    • Shyu BC, Olausson B, Andersson SA: Sympathetic and noradrenaline effects on C-fibre transmission: Single-unit analysis. Acta Physiol Scand 1989; 137:85-91. (Pubitemid 19228059)
    • (1989) Acta Physiologica Scandinavica , vol.137 , Issue.1 , pp. 85-91
    • Shyu, B.C.1    Olausson, B.2    Andersson, S.A.3
  • 52
    • 0035252641 scopus 로고    scopus 로고
    • Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin
    • DOI 10.1016/S0304-3959(00)00381-X, PII S030439590000381X
    • Fuchs PN, Meyer RA, Raja SN: Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin. Pain 2001; 90:15-23. (Pubitemid 32146554)
    • (2001) Pain , vol.90 , Issue.1-2 , pp. 15-23
    • Fuchs, P.N.1    Meyer, R.A.2    Raja, S.N.3
  • 54
    • 0027528905 scopus 로고
    • Autonomic dysfunction in gastrointestinal motility disorders
    • Bharucha AE, Camilleri M, Low PA, Zinsmeister AR: Autonomic dysfunction in gastrointestinal motility disorders. Gut 1993; 34:397-401. (Pubitemid 23080269)
    • (1993) Gut , vol.34 , Issue.3 , pp. 397-401
    • Bharucha, A.E.1    Camilleri, M.2    Low, P.A.3    Zinsmeister, A.R.4
  • 55
    • 4143124339 scopus 로고    scopus 로고
    • Autonomic cardiovascular responses are impaired in women with irritable bowel syndrome
    • DOI 10.1097/01.mcg.0000135362.35665.49
    • Waring WS, Chui M, Japp A, Nicol EF, Ford MJ: Autonomic cardiovascular responses are impaired in women with irritable bowel syndrome. J Clin Gastroenterol 2004; 38:658-63. (Pubitemid 39096794)
    • (2004) Journal of Clinical Gastroenterology , vol.38 , Issue.8 , pp. 658-663
    • Waring, W.S.1    Chui, M.2    Japp, A.3    Nicol, E.F.4    Ford, M.J.5
  • 56
    • 34447512368 scopus 로고    scopus 로고
    • Biology and therapy of fibromyalgia: Stress, the stress response system, and fibromyalgia (Letter)
    • Martinez-Lavin M: Biology and therapy of fibromyalgia: Stress, the stress response system, and fibromyalgia (Letter). Arthritis Res Ther 2007; 9:216
    • (2007) Arthritis Res Ther , vol.9 , pp. 216
    • Martinez-Lavin, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.