Transient allodynia pain models in mice for early assessment of analgesic activity

British Journal of Pharmacology

Volumn 153, Issue 4, 2008, Pages 769-774

  Gil, D W ^a   Cheevers, C V ^a   Donello, J E ^a  

^a ALLERGAN INC   (United States)

Author keywords

Allodynia; Neuropathic pain; Preclinical models

Indexed keywords

5 METHYLURAPIDIL; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMITRIPTYLINE; ANALGESIC AGENT; BICUCULLINE; CLONIDINE; GABAPENTIN; MEMANTINE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHENYLEPHRINE; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; SULPROSTONE; UNCLASSIFIED DRUG; ZM 325802;

ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG INHIBITION; MALE; MOUSE; NERVE INJURY; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT;

ADRENERGIC ALPHA-ANTAGONISTS; AMINES; AMITRIPTYLINE; ANALGESICS; ANIMALS; CLONIDINE; CYCLOHEXANECARBOXYLIC ACIDS; DINOPROSTONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; EXCITATORY AMINO ACID ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; HYPERALGESIA; INJECTIONS, INTRAPERITONEAL; INJECTIONS, SPINAL; MALE; MEMANTINE; MICE; MICE, INBRED C57BL; MORPHINE; N-METHYLASPARTATE; PAIN; PERIPHERAL NERVOUS SYSTEM; PHENYLEPHRINE; PIPERAZINES; PROSTAGLANDIN ANTAGONISTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, PROSTAGLANDIN E; REPRODUCIBILITY OF RESULTS; SPINAL CORD; SPINAL NERVES; TIME FACTORS;

EID: 39449126275     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707412     Document Type: Article

References (19)

1. Bennett GJ, Xie YK (1988). A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33: 87-107.
2. Chung K, Yoon YW, Chung JM (1997). Sprouting sympathetic fibers form synaptic varicosities in the dorsal root ganglion of the rat with neuropathic injury. Brain Res 751: 275-280.
3. Decosterd I, Woolf CJ (2000). Spared nerve injury: an animal model of persistent peripheral neuropathic pain. Pain 87: 149-158.
4. Dixon WJ (1980). Efficient analysis of experimental observations. Annu Rev Pharmacol Toxicol 20: 441-462.
5. Hylden JL, Wilcox GL (1982). Intrathecal opioids block a spinal action of substance P in mice: functional importance of both mu- and delta-receptors. Eur J Pharmacol 86: 95-98.
6. Kim SH, Chung JM (1992). An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50: 355-363.
7. Lemberg K, Kontinen VK, Viljakka K, Kylanlahti I, Yli-Kauhaluoma J, Kalso E (2006). Morphine, oxycodone, methadone and its enantiomers in different models of nociception in the rat. Anesth Analg 102: 1768-1774.
8. Lin Q, Wu J, Willis WD (1999). Dorsal root reflexes and cutaneous neurogenic inflammation after intradermal injection of capsaicin in rats. J Neurophysiol 82: 2602-2611.
9. McLachlan EM, Janig W, Devor M, Michaelis M (1993). Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature 363: 543-546.
10. Minami T, Matsumura S, Okuda-Ashitaka E, Shimamoto K, Sakimura K, Mishina M et al. (2001a). Characterization of the glutamatergic system for induction and maintenance of allodynia. Brain Res 895: 178-185.
11. Minami T, Nakano H, Kobayashi T, Sugimoto Y, Ushikubi F, Ichikawa A et al. (2001b). Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice. Br J Pharmacol 133: 438-444.
12. Minami T, Nishihara I, Uda R, Ito S, Hyodo M, Hayaishi O (1994a). Characterization of EP-receptor subtypes involved in allodynia and hyperalgesia induced by intrathecal administration of prostaglandin E2 to mice. Br J Pharmacol 112: 735-740.
13. Minami T, Nishihara I, Uda R, Ito S, Hyodo M, Hayaishi O (1994b). Involvement of glutamate receptors in allodynia induced by prostaglandins E2 and F2 alpha injected into conscious mice. Pain 57: 225-231.
14. Minami T, Okuda-Ashitaka E, Hori Y, Sakuma S, Sugimoto T, Sakimura K et al. (1999). Involvement of primary afferent C-fibres in touch-evoked pain (allodynia) induced by prostaglandin E2. Eur J Neurosci 11: 1849-1856.
15. Minami T, Uda R, Horiguchi S, Ito S, Hyodo M, Hayaishi O (1994c). Allodynia evoked by intrathecal administration of prostaglandin E2 to conscious mice. Pain 57: 217-223.
16. Oida H, Namba T, Sugimoto Y, Ushikubi F, Ohishi H, Ichikawa A et al. (1995). In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs. Br J Pharmacol 116: 2828-2837.
17. Sato J, Perl ER (1991). Adrenergic excitation of cutaneous pain receptors induced by peripheral nerve injury. Science 251: 1608-1610.
18. Yaksh TL, Harty GJ (1988). Pharmacology of the allodynia in rats evoked by high dose intrathecal morphine. J Pharmacol Exp Ther 244: 501-507.
19. Zou X, Lin Q, Willis WD (2001). NMDA or non-NMDA receptor antagonists attenuate increased Fos expression in spinal dorsal horn GABAergic neurons after intradermal injection of capsaicin in rats. Neuroscience 106: 171-182.