Olive (Olea europaea L.) leaf extract attenuates early diabetic neuropathic pain through prevention of high glucose-induced apoptosis: In vitro and in vivo studies

Journal of Ethnopharmacology

Volumn 136, Issue 1, 2011, Pages 188-196

  Kaeidi, Ayat ^a,c   Esmaeili Mahani, Saeed ^b   Sheibani, Vahid ^a   Abbasnejad, Mehdi ^b   Rasoulian, Bahram ^c   Hajializadeh, Zahra ^a   Afrazi, Samira ^a,b  

^a KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BAHONAR UNIVERSITY OF KERMAN   (Iran)

^c LORESTAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Apoptosis; Diabetic neuropathic pain; NGF treated PC12 cells; Olive leaf extract; Rats; Thermal hyperalgesia

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; BUTYLCRESOL; CASPASE 3; CELL MARKER; GLUCOSE; INSULIN; NERVE GROWTH FACTOR; OLEA EUROPAEA EXTRACT; OLIVE LEAF EXTRACT; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; ATTENUATION; CELL ASSAY; CELL DAMAGE; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEUROPATHY; DRUG POTENCY; ENZYME ACTIVATION; HYPERALGESIA; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; LATENT PERIOD; MALE; NERVE CELL LESION; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; OLIVE TREE; PHEOCHROMOCYTOMA; PHEOCHROMOCYTOMA CELL; PLANT LEAF; RAT; STREPTOZOCIN DIABETES; TAIL FLICK TEST;

ANALGESICS; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BIPHENYL COMPOUNDS; BLOOD GLUCOSE; CASPASE 3; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; FREE RADICAL SCAVENGERS; HYPERALGESIA; MALE; OLEA; PAIN; PHYTOTHERAPY; PICRATES; PLANT EXTRACTS; PLANT LEAVES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; SPINAL CORD;

ANIMALIA; OLEA EUROPAEA; RATTUS;

EID: 79958083225     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.04.038     Document Type: Article

References (46)

1. Adriaensen, H., Plaghki, L., Mathieu, C., Joffroy, A., Vissers, K., 2005. Critical review of oral drug treatments for diabetic neuropathic pain-clinical outcomes based on efficacy and safety data from placebo-controlled and direct comparative studies. Diabetes and Metabolism Research and Reviews 21, 231-240. (Pubitemid 40716154)
2. Allen, D.A., Yaqoob, M.M., Harwood, S.M., 2005. Mechanisms of high glucose-induced apoptosis and its relationship to diabetic complications. Journal of Nutritional Biochemistry 16, 705-713. (Pubitemid 41624792)
3. Amour, D., Smith, F.E.D.L., 1941. A method of determining loss of pain sensation. Journal of Pharmacology and Experimental Therapeutics 27, 74-79.
4. Bei, W., Zang, L., Guo, J., Peng, W., Xu, A., Good, D.A., Hu, Y., Wu, W., Hu, D., Zhu, X., Wei, M., Li, G., 2009. Neuroprotective effects of a standardized flavonoid extract from Diospyros kaki leaves. Journal of Ethnopharmacology 126, 134-142.
5. Benavente-Garcia, O., Castillo, J., Lorente, J., Ortuno, A., Del Rio, J.A., 2000. Antioxidant activity of phenolics extracted from Olea europea L. leaves. Food Chemistry 68, 457-462.
6. Bianco, A., Uccella, N., 2000. Biophenolic components of olives. Food Research International 33, 475-485. (Pubitemid 30427827)
7. Blois, M.S., 1958. Antioxidant determination by use of a stable free radical. Nature 181, 1199-1200.
8. Brownlee, M., 2001. Biochemistry and molecular cell biology of diabetic complications. Nature 414, 813-820. (Pubitemid 34000785)
9. Chandrasekaran, K., Swaminathan, K., Chatterjee, S., Dey, A., 2010. Apoptosis in HepG2 cells exposed to high glucose. Toxicology in Vitro 24, 387-396.
10. Chopra, K., Tiwari, V., Arora, V., Kuhad, A., 2010. Sesamol suppresses neuroinflammatory cascade in experimental model of diabetic neuropathy. Journal of Pain 11, 950-957.
11. Dekanski, D., Janicijevic-Hudomal, S., Ristic, S., Radonjic, N.V., Petronijevic, N.D., Piperski, V., Mitrovic, D.M., 2009. Attenuation of cold restraint stress-induced gastric lesions by an olive leaf extract. General Physiology and Biophysics 28, 135-142.
12. Denizot, F., Lang, R., 1986. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. Journal of Immunological Methods 89, 271-277. (Pubitemid 16080782)
13. Dyck, P.J., Dyck, P.J., Larson, T.S., O'Brien, P.C., Velosa, J.A., 2000. Patterns of quantitative sensation testing of hypoesthesia and hyperalgesia are predictive of diabetic polyneuropathy: a study of three cohorts. Nerve growth factor study group. Diabetes Care 23, 510-517. (Pubitemid 30185796)
14. Edwards, J.L., Vincent, A.M., Cheng, H.T., Feldman, E.L., 2008. Diabetic neuropathy: mechanisms to management. Pharmacology and Therapeutics 120, 1-34.
15. El, S.N., Karakaya, S., 2009. Olive tree (Olea europaea) leaves: potential beneficial effects on human health. Nutrition Review 67, 632-638.
16. Esmaeili-Mahani, S., Fereidoni, M., Javan, M., Maghsoudi, N., Motamedi, F., Ahmadiani, A., 2007. Nifedipine suppresses morphine-induced thermal hyperalgesia: evidence for the role of corticosterone. European Journal of Pharmacology 567, 95-101. (Pubitemid 46782819)
17. Esmaeili-Mahani, S., Shimokawa, N., Javan, M., Maghsoudi, N., Motamedi, F., Koibuchi, N., Ahmadiani, A., 2008. Low-dose morphine induces hyperalgesia through activation of Gαs, protein kinase C, and L-type Ca2+ channels in rats. Journal of Neuroscience Research 86, 471-479. (Pubitemid 351196753)
18. Esmaeili-Mahani, S., Rezaeezadeh-Roukerd, M., Esmaeilpour, K., Abbasnejad, M., Rasoulian, B., Sheibani, V., Kaeidi, A., Hajializadeh, Z., 2010. Olive (Olea europaea L.) leaf extract elicits antinociceptive activity potentiates morphine analgesia and suppresses morphine hyperalgesia in rats. Journal of Ethnopharmacology 132, 200-205.
19. Freshwater, J.D, Svensson, C.I., Malmberg, A.B., Calcutt, N.A., 2002. Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats. Diabetes 51, 2249-2255. (Pubitemid 34729032)
20. Gong, D., Geng, C., Jiang, L., Cao, J., Yoshimura, H., Zhong, L., 2009. Effects of hydroxytyrosol-20 on carrageenan-induced acute inflammation and hyperalgesia in rats. Phytotherapy Research 23, 646-650.
21. Hajializadeh, Z., Esmaeili-Mahani, S., Sheibani, V., Kaeidi, A., Atapour, M., Abbasnejad, M., 2010. Changes in the gene expression of specific G-protein subunits correlate with morphine insensitivity in streptozotocin-induced diabetic rats. Neuropeptides 44, 299-304.
22. Ilnytska, O., Lyzogubov, V.V., Stevens, M.J., Drel, V.R., Mashtalir, N., Pacher, P., Yorek, M.A., Obrosova, I.G., 2006. Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy. Diabetes 55, 1686-1694. (Pubitemid 44324121)
23. Ji, H.F., Zhang, H.Y., 2008. Multipotent natural agents to combat Alzheimer's disease functional spectrum and structural features. Acta Pharmacologica Sinica 29, 143-151.
24. Joseph, E.K., Levine, J.D., 2004. Caspase signalling in neuropathic and inflammatory pain in the rat. European Journal of Neuroscience 20, 2896-2902. (Pubitemid 40007283)
25. Kamboj, S.S., Vasishta, R.K., Sandhir, R., 2010. N-acetylcysteine inhibits hyperglycemia-induced oxidative stress and apoptosis markers in diabetic neuropathy. Journal of Neurochemistry 112, 77-91.
26. Kamenov, Z., Higashino, H., Todorova, M., Kajimoto, N., Suzuki, A., 2006. Physiological characteristics of diabetic neuropathy in sucrose-fed Otsuka Long-Evans Tokushima fatty rats. Methods Find Experimental and Clinical Pharmacology 28, 13-18.
27. Kumar, S., Arun, K.H., Kaul, C.L., Sharma, S.S., 2005. Effects of adenosine and adenosine A2A receptor agonist on motor nerve conduction velocity and nerve blood flow in experimental diabetic neuropathy. Neurolological Research 27, 60-66. (Pubitemid 40189607)
28. Lee, O.H., Lee, B.Y., 2010. Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. Bioresource Technology 101, 3751-3754.
29. Lee, O.H., Lee, B.Y., Lee, J., Lee, H.B., Son, J.Y., Park, C.S., Shetty, K., Kim, Y.C., 2009. Assessment of phenolics-enriched extract and fractions of olive leaves and their antioxidant activities. Bioresource Technology 100, 6107-6113.
30. Lelkes, E., Unsworth, B.R., Lelkes, P.I., 2001. Reactive oxygen species, apoptosis and altered NGF-induced signaling in PC12 pheochromocytoma cells cultured in elevated glucose: an in vitro cellular model for diabetic neuropathy. Neurotoxicology Research 3, 189-203. (Pubitemid 32936866)
31. Mohagheghi, F., Bigdeli, M.R., Rasoulian, B., Hashemi, P., Rashidi Pour, M., 2011. The neuroprotective effect of olive leaf extract is related to improved blood-brain barrier permeability and brain edema in rat with experimental focal cerebral ischemia. Phytomedicine 15, 170-175.
32. Omagari, K., Kato, S., Tsuneyama, K., Hatta, H., Sato, M., Hamasaki, M., Sadakane, Y., Tashiro, T., Fukuhata, M., Miyata, Y., Tamaru, S., Tanaka, K., Mune, M., 2010. Olive leaf extract prevents spontaneous occurrence of non-alcoholic steatohepatitis in SHR/NDmcr-cp rats. Pathology 42, 66-72.
33. Pazdro, R., Burgess, J.R., 2010. The role of vitamin E and oxidative stress in diabetes complications. Mechanisms of Ageing and development 131, 276-286.
34. Piga, R., Naito, Y., Kokura, S., Handa, O., Yoshikawa, T., 2010. Protective effect of serotonin derivatives on glucose-induced damage rat pheochromocytoma cells. British Journal of Nutrition 103, 25-31.
35. Russell, J.W., Sullivan, K.A., Windebank, A.J., Herrmann, D.N., Feldman, E.L., 1999. Neurons undergo apoptosis in animal and cell culture models of diabetes. Neurobiology of Disease 6, 347-363. (Pubitemid 29496214)
36. Russell, J.W., Golovoy, D., Vincent, A.M., Mahendru, P., Olzmann, J.A., Mentzer, A., Feldman, E.L., 2002. High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB Journal 16, 1738-1748. (Pubitemid 35340354)
37. Sekiguchi, M., Sekiguchi, Y., Konno, S., Kobayashi, H., Homma, Y., Kikuchi, S., 2009. Comparison of neuropathic pain and neuronal apoptosis following nerve root or spinal nerve compression. European Spine Journal 18, 1978-1985.
38. Sharifi, A.M., Eslami, H., Larijani, B., Davoodi, J., 2009. Involvement of caspase-8 -9, and -3 in high glucose-induced apoptosis in PC12 cells. Neuroscience Letter 459, 47-51.
39. Tesfaye, S., Tandan, R., Bastyr 3rd, E.J, Kles, K.A., Skljarevski, V., Price, K.L., 2007. Factors that impact symptomatic diabetic peripheral neuropathy in placebo-administered patients from two 1-year clinical trials. Diabetes Care 30, 2626-2632. (Pubitemid 47547808)
40. Tomlinson, D.R., Gardiner, N.J., 2008. Glucose neurotoxicity. Nature Review of Neuroscience 9, 36-45. (Pubitemid 350295687)
41. Vincent, A.M., Mclean, L.L., Backus, C., Feldman, L.L., 2005. Short-term hyperglycemia produces oxidative damage and apoptosis in neurons. FASEB Journal 959, 368-383.
42. Vincent, A.M., Russell, J.W., Sullivan, K.A., Backus, C., Hayes, J.M., McLean, L.L., Feldman, E.L., 2007. SOD2 protects neurons from injury in cell culture and animal models of diabetic neuropathy. Experimental Neurology 208, 216-227. (Pubitemid 350101499)
43. Vincent, A.M., Edwards, J.L., Sadidi, M., Feldman, E.L., 2008. The antioxidant response as a drug target in diabetic neuropathy. Current Drug Targets 9, 94-100, 2008.
44. Yokozawa, T., Kim, Y.A., Kim, H.Y., Lee, Y.A., Nonaka, G., 2007. Protective effect of persimmon peel polyphenol against high glucose-induced oxidative stress in LLC-PK1 cells. Food and Chemical Toxicology 45, 1979-1987. (Pubitemid 47238213)
45. Zimmermann, M., 1983. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16, 109-110. (Pubitemid 13058546)
46. Zochodne, D.W., 2008. Diabetic polyneuropathy: an update. Current Opinion in Neurology 21, 527-533.