Cellular reprogramming of somatic cells

Indian Journal of Experimental Biology

Volumn 49, Issue 6, 2011, Pages 409-415

  Sumer, Huseyin ^a   Liu, Jun ^a   Verma, Paul J ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Epigenetic reprogramming; Lineage specific reprogramming; Nuclear reprogramming; Pluripotency; Somatic cell; Stem cell

Indexed keywords

ANIMAL; CELL DEDIFFERENTIATION; CELL FUSION; CELL LINEAGE; CELL NUCLEUS TRANSPLANTATION; CLONING; CYTOLOGY; GENETIC EPIGENESIS; HUMAN; PLURIPOTENT STEM CELL; REVIEW;

ANIMALS; CELL DEDIFFERENTIATION; CELL FUSION; CELL LINEAGE; CLONING, ORGANISM; EPIGENESIS, GENETIC; HUMANS; INDUCED PLURIPOTENT STEM CELLS; NUCLEAR TRANSFER TECHNIQUES;

EID: 79958055218     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (70)

1. Briggs R & King T J, Transplantation of Living Nuclei From Blastula Cells into Enucleated Frogs' Eggs, Proc Natl Acad Sci U S A, 38(5) (1952) 455
2. Gurdon J B, Elsdale T R & Fischberg M, Sexually mature individuals of Xenopus laevis from the transplantation of single somatic nuclei, Nature, 182(4627) (1958) 64
3. Campbell K H, McWhir J, Ritchie W A & Wilmut I, Sheep cloned by nuclear transfer from a cultured cell line, Nature, 380(6569) (1996) 64
4. Hochedlinger K & Jaenisch R, Monoclonal mice generated by nuclear transfer from mature B and T donor cells, Nature, 415(6875) (2002) 1035
5. Lewis I M, Peura T T & Trounson A O, Large-scale applications of cloning technologies for agriculture: An industry perspective, Reprod Fertil Dev, 10(7-8) (1998) 677
6. Kubota C, Yamakuchi H, Todoroki J, Mizoshita K, Tabara N, Barber M & Yang X, Six cloned calves produced from adult fibroblast cells after long-term culture, Proc Natl Acad Sci U S A, 97(3) (2000) 990
7. Behboodi E, Memili E, Melican D, T, Destrempes M M, Overton S A, Williams J L, Flanagan P A, Butler R E, Liem H, Chen L H, Meade H M, Gavin W G & Echelard Y, Viable transgenic goats derived from skin cells, Transgenic Res, 13(3) (2004) 215
8. Polejaeva I A, Chen S H, Vaught T D, Page R L, Mullins J, Ball S, Dai Y, Boone J, Walker S, Ayares D L, Colman A & Campbell K H, Cloned pigs produced by nuclear transfer from adult somatic cells, Nature, 407(6800) (2000) 86
9. Galli C, Lagutina I, Crotti G, Colleoni S, Turini P, Ponderato N, Duchi R & Lazzari G, Pregnancy: a cloned horse born toits dam twin, Nature, 424(6949) (2003) 635
10. Paterson L, DeSousa P, Ritchie W, King T & Wilmut I, Application of reproductive biotechnology in animals: Implications and potentials. Applications of reproductive cloning, Anim Reprod Sci, 79(3-4) (2003) 137
11. Takahashi S & Ito Y, Evaluation of meat products from cloned cattle: Biological and biochemical properties, Cloning Stem Cells, 6(2) (2004) 165
12. Tome D, Dubarry M & Fromentin G, Nutritional value of milk and meat products derived from cloning, Cloning Stem Cells, 6(2) (2004) 172
13. Rudenko L & Matheson J C, The US FDA and animal cloning: Risk and regulatory approach, Theriogenology, 67 (1) (2007) 198
14. Rudenko L, Matheson J C & Sundlof S F, Animal cloning and the FDA--the risk assessment paradigm under public scrutiny, Nat Biotechnol, 25(1) (2007) 39
15. Rideout W M., 3rd; Hochedlinger, K, Kyba, M, Daley, G Q & Jaenisch, R, Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy, Cell, 109(1) (2002) 17
16. Sumer H, Liu J, Tat P A, Heffernan C, Jones K L & Verma P J, Somatic Cell Nuclear Transfer: Pros & Cons, J Stem Cells, 4(2) (2009) 85
17. French A J, Adams C A, Anderson L S, Kitchen J R, Hughes M R & Wood S H, Development of human cloned blastocysts following somatic cell nuclear transfer with adult fibroblasts, Stem Cell, 26(2) (2008) 485
18. Li J, Liu X, Wang H, Zhang S, Liu F, Wang X & Wang Y, Human embryos derived by somatic cell nuclear transfer using an alternative enucleation approach, Cloning Stem Cell, 11(1) (2009) 39
19. Stojkovic M, Stojkovic P, Leary C, Hall V J, Armstrong L, Herbert M, Nesbitt M, Lako M & Murdoch A, Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes, Reprod Biomed Online, 11(2) (2005) 226
20. Lucas J J & Terada N, Cell fusion and plasticity, Cytotechnology 41(2-3) (2003) 103
21. Miller R A & Ruddle F H, Pluripotent teratocarcinomathymus somatic cell hybrids, Cell,9(1) (1976) 45
22. Cowan C A, Atienza J, Melton D A & Eggan K, Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells, Science, 309(5739) (2005) 1369
23. Kimura H, Tada M, Nakatsuji N & Tada T, Histone code modifications on pluripotential nuclei of reprogrammed somatic cells, Mol Cell Biol, 24(13) (2004) 5710
24. Sumer H, Nicholls C, Pinto A R, Indraharan D, Liu J, Lim M L, Liu J P & Verma P J, Chromosomal and telomeric reprogramming following ES-somatic cell fusion, Chromosoma, 119(2) (2010) 9
25. Tada M, Tada T, Lefebvre L, Barton S C & Surani M A, Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells, EMBO J, 16(21) (1997) 6510
26. Tada M, Takahama Y, Abe K, Nakatsuji N & Tada T, Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells, Curr Biol, 11(19) (2001) 1553
27. Ying Q L, Nichols J, Evans E P & Smith A G, Changing potency by spontaneous fusion, Nature, 416(6880) (2002) 545
28. Pralong D, Mrozik K, Occhiodoro F, Wijesundara N, Sumer H, Van Boxtel A L, Trounson A & Verma P J, A novel method for somatic cell nuclear transfer to mouse embryonic stem cells, Cloning Stem Cell, 7(4) (2005) 265
29. Pralong D, Trounson A O & Verma P J, Cell fusion for reprogramming pluripotency: Toward elimination of the pluripotent genome, Stem Cell Rev, 2(4) (2006) 331.
30. Sumer H, Jones K L, Liu J, Rollo B N, van Boxtel A L, Pralong D & Verma P J, Transcriptional changes in somatic cells recovered from embryonic stem-somatic heterokaryons, Stem Cells Dev, 18(9) 2009 () 1361
31. Matsumura H, Tada M, Otsuji T, Yasuchika K, Nakatsuji N, Surani A & Tada T, Targeted chromosome elimination from ES-somatic hybrid cells, Nat Meth, 4(1) (2007) 23
32. Hakelien A M, Landsverk H B, Robl J M, Skalhegg B S & Collas P, Reprogramming fibroblasts to express T-cell functions using cell extracts, Nat Biotechnol, 20(5) (2002) 460
33. Han J, Sachdev P S & Sidhu K S, A combined epigenetic and non-genetic approach for reprogramming human somatic cells, PLoS One, 5(8) (2010).
34. Neri T, Monti M, Rebuzzini P, Merico V, Garagna S, Redi C A & Zuccotti M, Mouse fibroblasts are reprogrammed to Oct-4 and Rex-1 gene expression and alkaline phosphatase activity by embryonic stem cell extracts, Cloning Stem Cell, 9(3) (2007) 394.
35. Taranger, C K, Noer, A, Sorensen, A L, Hakelien, A M, Boquest, A C & Collas, P, Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells, Mol Biol Cell, 16(12) (2005) 5719
36. Walev I, Bhakdi S C, Hofmann F, Djonder N, Valeva A, Aktories K & Bhakdi S, Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O, Proc Natl Acad Sci U S A, 98(6) (2001) 3185
37. Gonda K & Kikyo N, Nuclear remodeling assay in Xenopus egg extract, Meth Mol Biol, 348 (2006) 247
38. Hansis C, Barreto G, Maltry N & Niehrs C, Nuclear reprogramming of human somatic cells by xenopus egg extract requires BRG1, Curr Biol, 14(16) (2004) 1475
39. Kikyo N, Wade P A, Guschin D, Ge H & Wolffe A P, Active remodeling of somatic nuclei in egg cytoplasm by the nucleosomal ATPase ISWI, Science, 289(5488) (2000) 2360
40. Collas P, Nuclear reprogramming in cell-free extracts, Philos Trans R Soc Lond B Biol Sci, 358(1436) (2003) 1389
41. Freberg C T, Dahl J A, Timoskainen S & Collas P, Epigenetic reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extract, Mol Biol Cell, 18(5) (2007) 1543
42. Takahashi K & Yamanaka S, Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, Cell, 126(4) (2006) 663
43. Hanna J, Wernig M, Markoulaki S, Sun C W, Meissner A, Cassady J P, Beard C, Brambrink T, Wu L C, Townes T M & Jaenisch R, Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin, Science, 318(5858) (2007) 1920
44. Okita K, Ichisaka T & Yamanaka S, Generation of germlinecompetent induced pluripotent stem cells, Nature, 448(7151) (2007) 313
45. Sumer H, Jones K L, Liu J, Heffernan C, Tat P A, Upton K R & Verma P J, Reprogramming of somatic cells after fusion with induced pluripotent stem cells and nuclear transfer embryonic stem cells, Stem Cells Dev, 19(2) (2010) 239
46. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K & Yamanaka S, Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell, 131(5) (2007) 861
47. Wernig M, Meissner A, Cassady J P & Jaenisch R, c-Myc is dispensable for direct reprogramming of mouse fibroblasts, Cell Stem Cell, 2(1) (2008) 10
48. Liu J, Sumer H, Leung J, Upton K, Dottori M, Pebay A & Verma P J, Late passage human fibroblasts induced to pluripotency are capable of directed neuronal differentiation, Cell Transplant, 2010.
49. Tat P A, Sumer H, Jones K L, Upton K & Verma P J, The efficient generation of induced pluripotent stem (iPS) cells from adult mouse adipose tissue-derived and neural stem cells, Cell Transplant 19(5) (2010) 525
50. Yu J, Vodyanik M A, Smuga-Otto K, Antosiewicz-Bourget J, Frane J L, Tian S, Nie J, Jonsdottir G A, Ruotti V, Stewart R, Slukvin II & Thomson J A, Induced pluripotent stem cell lines derived from human somatic cells, Science, 318(5858) (2007) 1917
51. Liu H, Zhu F, Yong J, Zhang P, Hou P, Li H, Jiang W, Cai J, Liu M, Cui K, Qu X, Xiang T, Lu D, Chi X, Gao G, Ji W, Ding M & Deng H, Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts, Cell Stem Cell, 3(6) (2008) 587
52. Li W, Wei W, Zhu S, Zhu J, Shi Y, Lin T, Hao E, Hayek A, Deng H & Ding S, Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors, Cell Stem Cell, 4(1) (2009) 16
53. Liao J, Cui C, Chen S, Ren J, Chen J, Gao Y, Li H, Jia N, Cheng L, Xiao H & Xiao L, Generation of induced pluripotent stem cell lines from adult rat cells, Cell Stem Cell, 4(1) 2009 () 11
54. Esteban M A, Xu J, Yang J, Peng M, Qin D, Li W, Jiang Z, Chen J, Deng K, Zhong M, Cai J, Lai L & Pei D, Generation of induced pluripotent stem cell lines from Tibetan miniature pig, J Biol Chem, 284(26) (2009) 17634
55. Ezashi T, Telugu B P, Alexenko A P, Sachdev S, Sinha S & Roberts R M, Derivation of induced pluripotent stem cells from pig somatic cells, Proc Natl Acad Sci U S A, 106(27) (2009) 10993
56. Wu Z, Chen J, Ren J, Bao L, Liao J, Cui C, Rao L, Li H, Gu Y, Dai H, Zhu H, Teng X, Cheng L & Xiao L, Generation of pig induced pluripotent stem cells with a drug-inducible system, J Mol Cell Biol, 1(1) (2009) 46
57. Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, Aoi T, Okita K, Mochiduki Y, Takizawa N & Yamanaka S, Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts, Nat Biotechnol, 26(1) (2008) 101
58. Huangfu D, Osafune K, Maehr R, Guo W, Eijkelenboom A, Chen S, Muhlestein W & Melton D A, Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2, Nat Biotechnol, 26(11) (2008) 1269
59. Shi Y, Do J T, Desponts C, Hahm H S, Scholer H R & Ding S, A combined chemical and genetic approach for the generation of induced pluripotent stem cells, Cell Stem Cell, 2(6) (2008) 525
60. Kim J B, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V, Arauzo-Bravo M J, Ruau D, Han D W, Zenke M & Scholer H R, Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors, Nature, 454(7204) (2008) 646
61. Stadtfeld M, Nagaya M, Utikal J, Weir G & Hochedlinger K, Induced pluripotent stem cells generated without viral integration, Science, 322(5903) (2008) 945
62. Woltjen K, Michael I P, Mohseni P, Desai R, Mileikovsky M, Hamalainen R, Cowling, R, Wang W, Liu P, Gertsenstein M, Kaji K, Sung H K & Nagy A, piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells, Nature, 458(7239) (2009) 766
63. Okita K, Nakagawa M, Hyenjong H, Ichisaka T & Yamanaka S, Generation of mouse induced pluripotent stem cells without viral vectors, Science, 322(5903) (2008) 949
64. Judson R L, Babiarz J E, Venere M & Blelloch R, Embryonic stem cell-specific microRNAs promote induced pluripotency, Nat Biotechnol, 27(5) (2009) 459
65. Warren L, Manos P D, Ahfeldt T, Loh Y H Li H, Lau F, Ebina W, Mandal P K, Smith Z D, Meissner A, Daley G Q, Brack A S, Collins J J, Cowan C, Schlaeger T M & Rossi D J, Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA, Cell Stem Cell, 2010.
66. Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee M J, Ji H, Ehrlich L I, Yabuuchi A, Takeuchi A, Cunniff K C, Hongguang H, McKinney-Freeman S, Naveiras O, Yoon T J, Irizarry R A, Jung N, Seita J, Hanna J, Murakami P, Jaenisch R, Weissleder R, Orkin S H, Weissman I L, Feinberg A P & Daley G Q, Epigenetic memory in induced pluripotent stem cells, Nature, 467(7313) (2010) 285.
67. Polo J M, Liu S, Figueroa M E, Kulalert W, Eminli S, Tan K Y, Apostolou E, Stadtfeld M, Li Y, Shioda T, Natesan S, Wagers A J, Melnick A, Evans T & Hochedlinger K, Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells, Nat Biotechnol, 28(8) (2010) 848
68. Vierbuchen T, Ostermeier A, Pang Z P, Kokubu Y, Sudhof T C & Wernig M, Direct conversion of fibroblasts to functional neurons by defined factors, Nature, 463(7284) (2010) 1035
69. Ieda M, Fu J D, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau B G & Srivastava D, Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors, Cell, 142(3) (2010) 375.
70. Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, Bernstein B E & Jaenisch R, In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state, Nature, 448(7151) (2007) 318.