Transcriptional changes in somatic cells recovered from embryonic stem-somatic heterokaryons

Stem Cells and Development

Volumn 18, Issue 9, 2009, Pages 1361-1368

  Sumer, Huseyin ^a   Jones, Karen L ^a   Liu, Jun ^a   Rollo, Benjamin N ^a   Van Boxtel, Antonius L ^b   Pralong, Daniele ^a   Verma, Paul J ^a  

^a MONASH UNIVERSITY   (Australia)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; GANCICLOVIR; GREEN FLUORESCENT PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FUSION; CELL NUCLEUS; CLONE; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENOME; HETEROKARYON; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOMATIC CELL; SUICIDE GENE; TETRAPLOIDY; TRANSGENE;

ALKALINE PHOSPHATASE; ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL FUSION; CELL NUCLEUS; CELLS, CULTURED; CLUSTER ANALYSIS; COCULTURE TECHNIQUES; EMBRYONIC STEM CELLS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GREEN FLUORESCENT PROTEINS; HYBRID CELLS; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLURIPOTENT STEM CELLS; POLYPLOIDY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 70450209668     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2008.0361     Document Type: Article

References (38)

1. Tada M, Y Takahama, K Abe, Nakatsuji N and Tada T. (2001). Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr Biol 11(19):1553-1558.
2. Cowan CA, J Atienza, DA Melton and K Eggan. (2005). Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309(5739):1369-1373.
3. Yu J, MA Vodyanik, He P, II Slukvin and JA Thomson. (2006). Human embryonic stem cells reprogram myeloid precursors following cell-cell fusion. Stem Cells 24(1):168-176.
4. Do JT and HR Scholer. (2005). Comparison of neurosphere cells with cumulus cells after fusion with embryonic stem cells: Reprogramming potential. Reprod Fertil Dev 17(1-2):143-149.
5. Hochedlinger K and R Jaenisch. (2006). Nuclear reprogramming and pluripotency. Nature 441(7097):1061-1067.
6. Blau HM, CP Chiu and C Webster. (1983). Cytoplasmic activation of human nuclear genes in stable heterocaryons. Cell 32(4):1171-1180.
7. Baron MH and T Maniatis. (1986). Rapid reprogramming of globin gene expression in transient heterokaryons. Cell 46:591-602.
8. Pavlath GK and HM Blau. (1986). Expression of muscle genes in heterokaryons depends on gene dosage. J Cell Biol 102(1):124-130.
9. Terranova R, CF Pereira, C Du Roure, M Merkenschlager and AG Fisher. (2006). Acquisition and extinction of gene expression programs are separable events in heterokaryon reprogramming. J Cell Sci 15(119):2065-2072.
10. Pereira CF, R Terranova, NK Ryan, J Santos, KJ Morris, W Cui, M Merkenschlager, and AG Fisher. (2008). Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2. PLoS Genet 4(9):e1000170.
11. Pralong D, K Mrozik, F Occhiodoro, N Wijesundara, H Sumer, AL Van Boxtel, A Trounson and PJ Verma. (2005). A novel method for somatic cell nuclear transfer to mouse embryonic stem cells. Cloning Stem Cells 7(4):265-271.
12. Szabo PE, K Hubner, H Scholer and JR Mann. (2002). Allelespecific expression of imprinted genes in mouse migratory primordial germ cells. Mech Dev 115(1-2):157-160.
13. Pralong D, ML Lim, I Vassiliev, K Mrozik, N Wijesundara, P Rathjen and PJ Verma. (2005). Tetraploid embryonic stem cells contribute to the inner cell mass of mouse blastocysts. Cloning Stem Cells 7(4):272-278.
14. Silva J, I Chambers, S Pollard and A Smith. (2006). Nanog promotes transfer of pluripotency after cell fusion. Nature 441(7096):997-1001.
15. Weimann JM, CB Johansson, A Trejo and HM Blau. (2003). Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant. Nat Cell Biol 5:959-966.
16. Johansson CB, S Youssef, K Koleckar, C Holbrook, R Doyonnas, SY Corbel, L Steinman, FMV Rossi and HM Blau. (2008). Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation. Nat Cell Biol 10:575-583.
17. Brambrink T, R Foreman, GG Welstead, CJ Lengner, M Wernig, H Suh and R Jaenisch. (2008). Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell 2(2):151-159.
18. Maherali N and K Hochedlinger. (2008). Guidelines and techniques for the generation of induced pluripotent stem cells. Cell Stem Cell 3(6):595-605.
19. Wilmut I, AE Schnieke, J Mcwhir, AJ Kind and KHS Campbell. (1997). Viable offspring derived from fetal and adult mammalian cells. Nature 385:810-813.
20. Hansis C, G Barreto, N Maltry and C Niehrs. (2004). Nuclear reprogramming of human somatic cells by xenopus egg extract requires BRG1. Curr Biol 14:1475-1480.
21. Hakelien A, HB Landsverk, JM Robl, BS Skalhegg and P Collas. (2002). Reprogramming fibroblasts to express T-cell functions using cell extracts. Nat Biotech 20:460-466.
22. Taranger CK, A Noer, AL Sorensen, A Hakelien, AC Boquest and P Collas. (2005). Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells. Mol Biol Cell 16:5719-5735.
23. Neri T, M Monti, P Rebuzzini, V Merico, S Garagna, CA Redi and M Zuccotti. (2007). Mouse fibroblasts are reprogrammed to Oct-4 and Rex-1 gene expression and alkaline phosphatase activity by embryonic stem cell extracts. Cloning Stem Cells 9:394-406.
24. Matsumura H, M Tada, T Otsuji, K Yasuchika, N Nakatsuji, A Surani and T Tada. (2007). Targeted chromosome elimination from ES-somatic hybrid cells. Nat Methods 4:23-25.
25. Mikkelsen TS, J Hanna, X Zhang, M Ku, M Wernig, P Schorderet, BE Bernstein, R Jaenisch, ES Lander and A Meissner. (2008) Dissecting direct reprogramming through integrative genomic analysis. Nature 454:49-55.
26. Huangfu D, R Maehr, W Guo, A Eijkelenboom, M Snitow, AE Chen and DA Melton. (2008). Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotech 26:795-797.
27. Sullivan S, S Pells, M Hooper, E Gallagher and J McWhir. (2006). Nuclear reprogramming of somatic cells by embryonic stem cells is affected by cell cycle stage. Cloning Stem Cells 8(3):174-188.
28. Takahashi K and S Yamanaka. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126(4):663-676.
29. Meissner A, M Wernig and R Jaenisch. (2007). Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat Biotechnol 25(10):1177-1181.
30. Okita K, Ichisaka T and Yamanaka S. (2007). Generation of germline-competent induced pluripotent stem cells. Nature 448:313-317.
31. Takahashi K, K Tanabe, M Ohnuki, M Narita, T Ichisaka, K Tomoda and S Yamanaka. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:1-12.
32. Yu J, MA Vodyanik, K Smuga-Otto, J Antosiewicz-Bourget, JL Frane, S Tian, J Nie, GA Jonsdottir, V Ruotti, R Stewart, II Slukin and AJ Thomson. (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science 318:1917-1920.
33. Hanna J, M Wernig, S Markoulaki, CW Sun, A Meissner, JP Cassady, C Beard, T Brambink, LC Wu, TM Townes and R Jaenisch. (2007). Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 318:1920-1923.
34. Kim JB, H Zaehres, G Wu, L Gentile, K Ko, V Sebastiano, MJ Arauzo-Bravo, D Ruau, DW Han, M Zenke and HR Scholer. (2008). Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 454:646-650.
35. Shi Y, JT Do, C Desponts, HS Hahm, HR Scholer and S Ding. (2008). A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cells 2(6):525-528.
36. Huangfu D, K Osafune, R Maehr, W Guo, A Eijkelenboom, S Chen, W Muhlestein and DA Melton. (2008). Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat Biotechol 26(11):2169-11275
37. Stadtfeld M, M Nagaya, J Utikal, G Weir and K Hochedlinger. (2008). Induced pluripotent stem cells generated without viral integration. Science 322(5903):945-949.
38. Okita K, M Nakagawa, H Hyenjong, T Ichisaka and S Yamanaka. (2008). Generation of mouse induced pluripotent stem cells without viral vectors. Science 322(5903):949-953.