Chromosomal and telomeric reprogramming following ES-somatic cell fusion

Chromosoma

Volumn 119, Issue 2, 2010, Pages 167-176

  Sumer, H ^a   Nicholls, Craig ^b   Pinto, Alexander R ^b   Indraharan, Dinesh ^a   Liu, Jun ^a   Lim, Mei Ling ^a   Liu, Jun Ping ^b   Verma, Paul J ^a  

^a MONASH UNIVERSITY   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DYSKERIN; OCTAMER TRANSCRIPTION FACTOR 4; STAGE SPECIFIC EMBRYO ANTIGEN 1; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FUSION; CHROMOSOME; CHROMOSOME LOSS; CHROMOSOME PAIRING; CONTROLLED STUDY; DIPLOIDY; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; FETUS; GENE EXPRESSION; GERM LAYER; MALE; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; SISTER CHROMATID; SOMATIC CELL; TELOMERE; TERATOMA; TETRAPLOIDY;

ANIMALS; ANTIGENS, CD15; CELL CULTURE TECHNIQUES; CELL CYCLE PROTEINS; CELL FUSION; CELL LINE; CHROMOSOME SEGREGATION; EMBRYONIC STEM CELLS; FIBROBLASTS; GENE EXPRESSION REGULATION; HYBRID CELLS; MICE; NUCLEAR PROTEINS; OCTAMER TRANSCRIPTION FACTOR-3; PLOIDIES; RNA; TELOMERASE; TELOMERE;

EID: 77953274671     PISSN: 00095915     EISSN: 14320886     Source Type: Journal    
DOI: 10.1007/s00412-009-0245-1     Document Type: Article

References (38)

1. Betts D, Bordignon V, Hill J, Winger Q, Westhusin M, Smith L, King W (2001) Reprogramming of telomerase activity and rebuilding of telomere length, in cloned cattle. PNAS 98(3):1077-1.082
2. Blackburn. EH (1991) Telomeres. Trends Biochem Sci 16(10):378-381
3. Cuthbert AP, Bond J, Trott DA, Gill S, Broni J, Marriott A, Khoudoli G, Parkinson EK, Coopa CS, Newbold RF (1999) Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells. J Natl Cancer Inst 91(l):37-45
4. Cowan CA, Atienza J, Melton DA, Eggan K (2005) Nuclear reprogramming of somatic cells after fusion, with, human embryonic stem cells. Science 309(5739): 1369-1373
5. de Lange T (2005) Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev 19(18):2100-2110
6. Ducrest AL, Amacker M, Mathieu YD, Cuťhbert AP, Trott DA, Newbold RF, Nabholz M, Lingner J (2001) Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-M.yc activity. Cancer Res 61(20):7594-7602
7. Hanada H, Takeda K, Tagami T, Nirasawa K, Akagi S, Adachi N, Takahashi S, Izaike Y, Iwamoto M, Fuchimoto D, Miyashita N, Kubo M, Onishi A, King WA (2005) Chromosomal, instability in the cattle clones derived by somatic cell nuclear-transfer. Mol Reprod Dev 71(l):36-44
8. Jeon HY, Hyun SH, Lee GS, Kim HS, Kim S, Jeong YW, Kang SK, Lee BC, Han JY, Ahn C, Hwang WS (2005) The analysis of telomere length and telomerase activity in cloned pigs and cows. Mol Reprod. Dev 71(3):315-320
9. Kishigami S, Wakayama S, Hosoi Y, Iritani A, Wakayama T (2008) Somatic cell nuclear transfa: infinite reproduction of a unique diploid genome. Exp Cell Res 314(9): 1945-1950
10. Kugoh H, Shigenami K, Funaki K, Barrett JC, Oshimura M. (2003) Human chromosome 5 carries a putative telomerase repressor gene. Genes Chromosomes Cancer 36(1):37-47
11. Lansdorp PM. (2008) Telomeres, stem cells, and hematology. Blood 111(4):1759-1766
12. Li H, Zhao LL, Funder JW, Liu JP (1997) Protein phosphatase 2A inhibits nuclear telomerase activity in human breast canea cells. J Biol Chem 272:16729-1.6732
13. Liu L, Bailey SM, Okuka M, Munoz P, Li C, Zhou. L, Wu C, Czerwiec E, Sandler L, Seyfang A, Blasco MA, Keefe DL (2007) Telomere lengthening early in development. Nat Cell Biol 9 (12):1436-1441
14. Marion RM, Strati. K, Li H, Tejera A, Schoeftner S, Ortega S, Serrano M, Blasco MA (2009) Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. Cell Stem Cell 4 (2):141-154
15. Matveeva NM, Shilov AG, Kaftanovskaya EM, Maximovsky LP, Zhelezova AI, Golubitsa AN, Bayborodin SI, Fokina MM, Serov OL (1998) In vitro and in vivo study of pluripotency in intraspecific hybrid cells obtained by fusion of murine embryonic stem cells with splenocytes. Mol Reprod Dev 50 (2):128-138
16. Matveeva NM, Pristyazhnyuk IE, Temirova SA, Menzorov AG, Vasilkova A, Shilov AG, Smith A, Serov OL (2005) Unequal segregation of parental chromosomes in embryonic stem cell hybrids. Mol Reprod Dev 71(3):305-314
17. Morrish TA, Greider CW (2009) Short telomeres initiate telomere recombination in primary and tumor cells. PLoS Genet 5(1): el000357
18. Ohmura H, Tahara H, Suzuki M, Ide T Shimizu M, Yoshida MA, Tahara E, Shay JW, Barrett JC, Oshimura M, (1995) Restoration of the cellular senescence program and repression of telomerase by human chromosome 3. Jpn J Cancer Res 86 (10):899-904
19. Osterhage JL, Friedman KL (2009) Chromosome end maintenance by telomerase. J Biol Chem. doi:101074/jbcR900011200
20. Palm W, de Lange T (2008) How shelterin protects mammalian telomeres. Annu Rev Genet 42:301-334
21. Perrem K, Colgin LM, Neumann. AA, Yeager TR, Reddel RR (2001) Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells. Mol. Cell Biol 21 (12):3862-3875
22. Pralong D, Mrozik K, Occhiodoro F, Wijesundara N, Sumer H, Van Boxtel AL, Trounson A, Verma PJ (2005) A novel method for somatic cell nuclear transfer to mouse embryonic stem cells. Cloning Stem Cells 7(4):265-271
23. Sagawa Y, Nishi H, lsaka K, Fujito A, Takayama M (2001) The correlation of TERT expression with c-myc expression in cervical cancer. Cancer Lett 168(l):45-50
24. Shiels PG, Kind AJ, Campbell KH, Waddington. D, Wilmut I, Colman A, Schnieke AE (1999) Analysis of telomere lengths in cloned sheep. Nature 399(6734):316-317
25. Suma H, Jones KL, Liu. J, Rollo BN, van Boxtel AL, Pralong D, Verma PJ (2009) Transcriptional changes in somatic cells recovered from ES-somatic heterokaryons. Stem Cells Dev. doi:101089/scd20080361.
26. Stadtfeld M, Maherali N, Breault DT, Hochedlinger K (2008) Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell. Stem Cell 2(3):230-240
27. Tada M, Tada T, Lefebvre L, Barton SC, Surani MA (1997) Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells. EMBO J 16:6510-6520
28. Tada M, Takahama Y, Abe K, Nakatsuji N, Tada T (2001) Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr Biol 11:1553-1558
29. Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-676
30. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S (2007) Induction of pluripotent stem, cells from adult human fibroblasts by defined factors. Cell 131:1-12
31. Tanaka H, Horikawa I, Kugoh H, Shimizu M, Barrett JC, Oshimura M, (1.999) Telomerase-independent senescence of human immortal cells induced by microcell-mediated chromosome transfer. Mol Carcinog 25(4):249-255
32. Tycowski KT, Shu MD, Kukoyi A, Steitz JA (2009) A conserved WD40 protein binds the Cajal body localization signal of scaRNP particles. Mol Cell 34(1):47-57
33. Tian XC, Xu J, Yang X (2000) Normal telomere lengths found in cloned, cattle. Nat Genet 26(3):272-273
34. Vasilkova AA, Kizilova HA, Puzakov MV, Shilov AG, Zhelezova AI, Golubitsa AN, Battulin NR, Vedemikov VE, Menzorov AG, Matveeva NM, Serov OL (2007) Dominant manifestation of pluripotency in embryonic stem, cell hybrids with, various numbers of somatic chromosomes. Mol Reprod Dev 74(8):941-951
35. Venteicher AS, Abreu EB, Meng Z, McCann KE, Terns RM, Veenstra TD, Terns MP, Artandi SE (2009) A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. Science 323(5914):644-648
36. Wang F, Podell ER, Zaug AJ, Yang Y, Baciu P, Cech TR, Lei M (2007) The POTI-TPP1 telomere complex is a telomerase processivity factor. Nature 445(7127):506-510
37. Wu KJ, Grandori C, Amacker M, Simon-Vermot N, Polack A, Lingner J, Dalla-Favera R (1999) Direct activation, of TERT transcription by c-MYC. Nat Genet 21(2):220-224
38. Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, Slukin II, Thomson AJ (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science 318:1917-1920