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Volumn 36, Issue 6, 2011, Pages 314-319

PAMPer and tRIGer: Ligand-induced activation of RIG-I

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; INTERFERON; NUCLEIC ACID; PATHOGEN ASSOCIATED MOLECULAR PATTERN; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG;

EID: 79958053294     PISSN: 09680004     EISSN: 09680004     Source Type: Journal    
DOI: 10.1016/j.tibs.2011.03.003     Document Type: Review
Times cited : (8)

References (42)
  • 1
    • 34347273014 scopus 로고    scopus 로고
    • Human primary immunodeficiencies of type I interferons
    • Jouanguy E., et al. Human primary immunodeficiencies of type I interferons. Biochimie 2007, 89:878-883.
    • (2007) Biochimie , vol.89 , pp. 878-883
    • Jouanguy, E.1
  • 2
    • 0034767753 scopus 로고    scopus 로고
    • Antiviral actions of interferons
    • Samuel C.E. Antiviral actions of interferons. Clin. Microbiol. Rev. 2001, 14:778-809.
    • (2001) Clin. Microbiol. Rev. , vol.14 , pp. 778-809
    • Samuel, C.E.1
  • 3
    • 77952316540 scopus 로고    scopus 로고
    • An integrated view of humoral innate immunity: pentraxins as a paradigm
    • Bottazzi B., et al. An integrated view of humoral innate immunity: pentraxins as a paradigm. Annu. Rev. Immunol. 2010, 28:157-183.
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 157-183
    • Bottazzi, B.1
  • 4
    • 77951877953 scopus 로고    scopus 로고
    • Identification and functions of pattern-recognition receptors
    • Kumagai Y., Akira S. Identification and functions of pattern-recognition receptors. J. Allergy Clin. Immunol. 2010, 125:985-992.
    • (2010) J. Allergy Clin. Immunol. , vol.125 , pp. 985-992
    • Kumagai, Y.1    Akira, S.2
  • 5
    • 67649774331 scopus 로고    scopus 로고
    • Galectins in innate immunity: dual functions of host soluble beta-galactoside-binding lectins as damage-associated molecular patterns (DAMPs) and as receptors for pathogen-associated molecular patterns (PAMPs)
    • Sato S., et al. Galectins in innate immunity: dual functions of host soluble beta-galactoside-binding lectins as damage-associated molecular patterns (DAMPs) and as receptors for pathogen-associated molecular patterns (PAMPs). Immunol. Rev. 2009, 230:172-187.
    • (2009) Immunol. Rev. , vol.230 , pp. 172-187
    • Sato, S.1
  • 6
    • 38649123396 scopus 로고    scopus 로고
    • The future of toll-like receptor therapeutics
    • Parkinson T. The future of toll-like receptor therapeutics. Curr. Opin. Mol. Ther. 2008, 10:21-31.
    • (2008) Curr. Opin. Mol. Ther. , vol.10 , pp. 21-31
    • Parkinson, T.1
  • 7
    • 35648930568 scopus 로고    scopus 로고
    • Update on toll-like receptor-directed therapies for human disease
    • Tse K., Horner A.A. Update on toll-like receptor-directed therapies for human disease. Ann. Rheum Dis. 2007, 66(Suppl. 3):iii77-iii80.
    • (2007) Ann. Rheum Dis. , vol.66 , Issue.SUPPL. 3
    • Tse, K.1    Horner, A.A.2
  • 8
    • 68849096790 scopus 로고    scopus 로고
    • Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells
    • Besch R., et al. Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells. J. Clin. Invest. 2009, 119:2399-2411.
    • (2009) J. Clin. Invest. , vol.119 , pp. 2399-2411
    • Besch, R.1
  • 9
    • 77953462221 scopus 로고    scopus 로고
    • Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication
    • Chakravarthy K.V., et al. Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:10172-10177.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 10172-10177
    • Chakravarthy, K.V.1
  • 10
    • 77954372029 scopus 로고    scopus 로고
    • Targeted activation of RNA helicase retinoic acid-inducible gene-I induces proimmunogenic apoptosis of human ovarian cancer cells
    • Kubler K., et al. Targeted activation of RNA helicase retinoic acid-inducible gene-I induces proimmunogenic apoptosis of human ovarian cancer cells. Cancer Res. 2010, 70:5293-5304.
    • (2010) Cancer Res. , vol.70 , pp. 5293-5304
    • Kubler, K.1
  • 11
    • 78651410969 scopus 로고    scopus 로고
    • Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine
    • Luke J.M., et al. Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine. J. Virol. 2011, 85:1370-1383.
    • (2011) J. Virol. , vol.85 , pp. 1370-1383
    • Luke, J.M.1
  • 12
    • 77952458811 scopus 로고    scopus 로고
    • 5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication
    • Ranjan P., et al. 5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication. Virol. J. 2010, 7:102.
    • (2010) Virol. J. , vol.7 , pp. 102
    • Ranjan, P.1
  • 13
    • 69249202248 scopus 로고    scopus 로고
    • RIG-I activation inhibits ebolavirus replication
    • Spiropoulou C.F., et al. RIG-I activation inhibits ebolavirus replication. Virology 2009, 392:11-15.
    • (2009) Virology , vol.392 , pp. 11-15
    • Spiropoulou, C.F.1
  • 14
    • 68649096389 scopus 로고    scopus 로고
    • Cytoplasmic nucleic acid sensors in antiviral immunity
    • Ranjan P., et al. Cytoplasmic nucleic acid sensors in antiviral immunity. Trends Mol. Med. 2009, 15:359-368.
    • (2009) Trends Mol. Med. , vol.15 , pp. 359-368
    • Ranjan, P.1
  • 15
    • 58149185107 scopus 로고    scopus 로고
    • RIG-I and dsRNA-induced IFNbeta activation
    • Hausmann S., et al. RIG-I and dsRNA-induced IFNbeta activation. PLoS ONE 2008, 3:e3965.
    • (2008) PLoS ONE , vol.3
    • Hausmann, S.1
  • 16
    • 59449102889 scopus 로고    scopus 로고
    • Agonist and antagonist recognition by RIG-I, a cytoplasmic innate immunity receptor
    • Ranjith-Kumar C.T., et al. Agonist and antagonist recognition by RIG-I, a cytoplasmic innate immunity receptor. J. Biol. Chem. 2009, 284:1155-1165.
    • (2009) J. Biol. Chem. , vol.284 , pp. 1155-1165
    • Ranjith-Kumar, C.T.1
  • 17
    • 66149114745 scopus 로고    scopus 로고
    • Nucleotide sequences and modifications that determine RIG-I/RNA binding and signaling activities
    • Uzri D., Gehrke L. Nucleotide sequences and modifications that determine RIG-I/RNA binding and signaling activities. J. Virol. 2009, 83:4174-4184.
    • (2009) J. Virol. , vol.83 , pp. 4174-4184
    • Uzri, D.1    Gehrke, L.2
  • 18
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama M., et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 2004, 5:730-737.
    • (2004) Nat. Immunol. , vol.5 , pp. 730-737
    • Yoneyama, M.1
  • 19
    • 46949097299 scopus 로고    scopus 로고
    • Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5
    • Kato H., et al. Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5. J. Exp. Med. 2008, 205:1601-1610.
    • (2008) J. Exp. Med. , vol.205 , pp. 1601-1610
    • Kato, H.1
  • 20
    • 33750976374 scopus 로고    scopus 로고
    • 5'-Triphosphate RNA is the ligand for RIG-I
    • Hornung V., et al. 5'-Triphosphate RNA is the ligand for RIG-I. Science 2006, 314:994-997.
    • (2006) Science , vol.314 , pp. 994-997
    • Hornung, V.1
  • 21
    • 33750984771 scopus 로고    scopus 로고
    • RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
    • Pichlmair A., et al. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science 2006, 314:997-1001.
    • (2006) Science , vol.314 , pp. 997-1001
    • Pichlmair, A.1
  • 22
    • 33646342149 scopus 로고    scopus 로고
    • Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
    • Kato H., et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006, 441:101-105.
    • (2006) Nature , vol.441 , pp. 101-105
    • Kato, H.1
  • 23
    • 37349052379 scopus 로고    scopus 로고
    • Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity
    • Loo Y.M., et al. Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. J. Virol. 2008, 82:335-345.
    • (2008) J. Virol. , vol.82 , pp. 335-345
    • Loo, Y.M.1
  • 24
    • 0028233381 scopus 로고
    • RNA template-directed RNA synthesis by T7 RNA polymerase
    • Cazenave C., Uhlenbeck O.C. RNA template-directed RNA synthesis by T7 RNA polymerase. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:6972-6976.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 6972-6976
    • Cazenave, C.1    Uhlenbeck, O.C.2
  • 25
    • 0028924624 scopus 로고
    • Self-coded 3'-extension of run-off transcripts produces aberrant products during in vitro transcription with T7 RNA polymerase
    • Triana-Alonso F.J., et al. Self-coded 3'-extension of run-off transcripts produces aberrant products during in vitro transcription with T7 RNA polymerase. J. Biol. Chem. 1995, 270:6298-6307.
    • (1995) J. Biol. Chem. , vol.270 , pp. 6298-6307
    • Triana-Alonso, F.J.1
  • 26
    • 68049089651 scopus 로고    scopus 로고
    • Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus
    • Schlee M., et al. Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus. Immunity 2009, 31:25-34.
    • (2009) Immunity , vol.31 , pp. 25-34
    • Schlee, M.1
  • 27
    • 67749133995 scopus 로고    scopus 로고
    • 5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
    • Schmidt A., et al. 5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:12067-12072.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 12067-12072
    • Schmidt, A.1
  • 28
    • 38649089789 scopus 로고    scopus 로고
    • The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
    • Cui S., et al. The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I. Mol. Cell 2008, 29:169-179.
    • (2008) Mol. Cell , vol.29 , pp. 169-179
    • Cui, S.1
  • 29
    • 67650510680 scopus 로고    scopus 로고
    • Solution structures of cytosolic RNA sensors MDA5 and LGP2 C-terminal domains: Identification of the RNA recognition loop in RIG-I like receptors
    • Takahasi K., et al. Solution structures of cytosolic RNA sensors MDA5 and LGP2 C-terminal domains: Identification of the RNA recognition loop in RIG-I like receptors. J. Biol. Chem. 2009, 284:17465-17474.
    • (2009) J. Biol. Chem. , vol.284 , pp. 17465-17474
    • Takahasi, K.1
  • 30
    • 39649092731 scopus 로고    scopus 로고
    • Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses
    • Takahasi K., et al. Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses. Mol. Cell 2008, 29:428-440.
    • (2008) Mol. Cell , vol.29 , pp. 428-440
    • Takahasi, K.1
  • 31
    • 79952325540 scopus 로고    scopus 로고
    • Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate
    • Lu C., et al. Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate. Nucleic Acids Res. 2010, 39:1565-1575.
    • (2010) Nucleic Acids Res. , vol.39 , pp. 1565-1575
    • Lu, C.1
  • 32
    • 77954386541 scopus 로고    scopus 로고
    • Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I
    • Wang Y., et al. Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I. Nat. Struct. Mol. Biol. 2010, 17:781-787.
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 781-787
    • Wang, Y.1
  • 33
    • 77955481642 scopus 로고    scopus 로고
    • The structural basis of 5' triphosphate double-stranded RNA recognition by RIG-I C-terminal domain
    • Lu C., et al. The structural basis of 5' triphosphate double-stranded RNA recognition by RIG-I C-terminal domain. Structure 2010, 18:1032-1043.
    • (2010) Structure , vol.18 , pp. 1032-1043
    • Lu, C.1
  • 34
    • 34547434301 scopus 로고    scopus 로고
    • Double-stranded DNA and double-stranded RNA induce a common antiviral signaling pathway in human cells
    • Cheng G., et al. Double-stranded DNA and double-stranded RNA induce a common antiviral signaling pathway in human cells. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:9035-9040.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 9035-9040
    • Cheng, G.1
  • 35
    • 70349459734 scopus 로고    scopus 로고
    • RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
    • Ablasser A., et al. RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate. Nat. Immunol. 2009, 10:1065-1072.
    • (2009) Nat. Immunol. , vol.10 , pp. 1065-1072
    • Ablasser, A.1
  • 36
    • 68049092912 scopus 로고    scopus 로고
    • RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
    • Chiu Y.H., et al. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 2009, 138:576-591.
    • (2009) Cell , vol.138 , pp. 576-591
    • Chiu, Y.H.1
  • 37
    • 78149324490 scopus 로고    scopus 로고
    • RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP
    • Malathi K., et al. RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP. RNA 2010, 16:2108-2119.
    • (2010) RNA , vol.16 , pp. 2108-2119
    • Malathi, K.1
  • 38
    • 79953166075 scopus 로고    scopus 로고
    • Short dsRNAs with an overhanging 5 prime ppp-nucleotide, as found in arenavirus genomes, act as RIG-I decoys
    • Marq, J.B. et al. Short dsRNAs with an overhanging 5 prime ppp-nucleotide, as found in arenavirus genomes, act as RIG-I decoys. J. Biol. Chem. 286, 6108-16.
    • J. Biol. Chem. , vol.286 , pp. 6108-16
    • Marq, J.B.1
  • 39
    • 77953308262 scopus 로고    scopus 로고
    • Unpaired 5' ppp-nucleotides, as found in arenavirus double-stranded RNA panhandles, are not recognized by RIG-I
    • Marq J.B., et al. Unpaired 5' ppp-nucleotides, as found in arenavirus double-stranded RNA panhandles, are not recognized by RIG-I. J. Biol. Chem. 2010, 285:18208-18216.
    • (2010) J. Biol. Chem. , vol.285 , pp. 18208-18216
    • Marq, J.B.1
  • 40
    • 77957997708 scopus 로고    scopus 로고
    • Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing
    • Baum A., et al. Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:16303-16308.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 16303-16308
    • Baum, A.1
  • 41
    • 75749140581 scopus 로고    scopus 로고
    • RIG-I detects viral genomic RNA during negative-strand RNA virus infection
    • Rehwinkel J., et al. RIG-I detects viral genomic RNA during negative-strand RNA virus infection. Cell 2010, 140:397-408.
    • (2010) Cell , vol.140 , pp. 397-408
    • Rehwinkel, J.1
  • 42
    • 77954912141 scopus 로고    scopus 로고
    • Influenza A virus-generated small RNAs regulate the switch from transcription to replication
    • Perez J.T., et al. Influenza A virus-generated small RNAs regulate the switch from transcription to replication. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:11525-11530.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 11525-11530
    • Perez, J.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.