-
1
-
-
39649102758
-
Functional GI disorders: From animal models to drug development
-
Mayer EA, Bradesi S, Chang L, Spiegel BM, Bueller JA, Naliboff BD. Functional GI disorders: from animal models to drug development. Gut 2008; 57: 384-404
-
(2008)
Gut
, vol.57
, pp. 384-404
-
-
Mayer, E.A.1
Bradesi, S.2
Chang, L.3
Spiegel, B.M.4
Bueller, J.A.5
Naliboff, B.D.6
-
2
-
-
48449085385
-
P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity
-
Xu GY, Shenoy M, Winston JH, Mittal S, Pasricha PJ. P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity. Gut 2008; 57: 1230-1237
-
(2008)
Gut
, vol.57
, pp. 1230-1237
-
-
Xu, G.Y.1
Shenoy, M.2
Winston, J.H.3
Mittal, S.4
Pasricha, P.J.5
-
3
-
-
0026727782
-
Three types of sodium channels in adult rat dorsal root ganglion neurons
-
Caffrey JM, Eng DL, Black JA, Waxman SG, Kocsis JD. Three types of sodium channels in adult rat dorsal root ganglion neurons. Brain Res 1992; 592: 283-297
-
(1992)
Brain Res
, vol.592
, pp. 283-297
-
-
Caffrey, J.M.1
Eng, D.L.2
Black, J.A.3
Waxman, S.G.4
Kocsis, J.D.5
-
4
-
-
0037440084
-
Sensory and electrophysiological properties of guinea-pig sensory neurones expressing Nav 1.7 (PN1) Na+ channel alpha subunit protein
-
Djouhri L, Newton R, Levinson SR, Berry CM, Carruthers B, Lawson SN. Sensory and electrophysiological properties of guinea-pig sensory neurones expressing Nav 1.7 (PN1) Na+ channel alpha subunit protein. J Physiol 2003; 546: 565-576
-
(2003)
J Physiol
, vol.546
, pp. 565-576
-
-
Djouhri, L.1
Newton, R.2
Levinson, S.R.3
Berry, C.M.4
Carruthers, B.5
Lawson, S.N.6
-
5
-
-
63449107353
-
Voltage-gated sodium channels in pain states: Role in pathophysiology and targets for treatment
-
Dib-Hajj SD, Binshtok AM, Cummins TR, Jarvis MF, Samad T, Zimmermann K. Voltage-gated sodium channels in pain states: role in pathophysiology and targets for treatment. Brain Res Rev 2009; 60: 65-83
-
(2009)
Brain Res Rev
, vol.60
, pp. 65-83
-
-
Dib-Hajj, S.D.1
Binshtok, A.M.2
Cummins, T.R.3
Jarvis, M.F.4
Samad, T.5
Zimmermann, K.6
-
6
-
-
33751229668
-
Roles of voltage-dependent sodium channels in neuronal development, pain, and neurodegeneration
-
Wada A. Roles of voltage-dependent sodium channels in neuronal development, pain, and neurodegeneration. J Pharmacol Sci 2006; 102: 253-268
-
(2006)
J Pharmacol Sci
, vol.102
, pp. 253-268
-
-
Wada, A.1
-
8
-
-
77953667423
-
Pain channelopathies
-
Cregg R, Momin A, Rugiero F, Wood JN, Zhao J. Pain channelopathies. J Physiol 2010; 588: 1897-1904
-
(2010)
J Physiol
, vol.588
, pp. 1897-1904
-
-
Cregg, R.1
Momin, A.2
Rugiero, F.3
Wood, J.N.4
Zhao, J.5
-
10
-
-
77951456829
-
Nerve compression activates selective nociceptive pathways and upregulates peripheral sodium channel expression in Schwann cells
-
Frieboes LR, Palispis WA, Gupta R. Nerve compression activates selective nociceptive pathways and upregulates peripheral sodium channel expression in Schwann cells. J Orthop Res 2010; 28: 753-761
-
(2010)
J Orthop Res
, vol.28
, pp. 753-761
-
-
Frieboes, L.R.1
Palispis, W.A.2
Gupta, R.3
-
11
-
-
77951911566
-
Exploring the role of nociceptor- specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice
-
Leo S, D'Hooge R, Meert T. Exploring the role of nociceptor- specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice. Behav Brain Res 2010; 208: 149-157
-
(2010)
Behav Brain Res
, vol.208
, pp. 149-157
-
-
Leo, S.1
D'Hooge, R.2
Meert, T.3
-
12
-
-
77950429077
-
Pain perception is altered by a nucleotide polymorphism in SCN9A
-
Reimann F, Cox JJ, Belfer I, Diatchenko L, Zaykin DV, McHale DP, Drenth JP, Dai F, Wheeler J, Sanders F, Wood L, Wu TX, Karppinen J, Nikolajsen L, Männikkö M, Max MB, Kiselycznyk C, Poddar M, Te Morsche RH, Smith S, Gibson D, Kelempisioti A, Maixner W, Gribble FM, Woods CG. Pain perception is altered by a nucleotide polymorphism in SCN9A. Proc Natl Acad Sci USA 2010; 107: 5148-5153
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5148-5153
-
-
Reimann, F.1
Cox, J.J.2
Belfer, I.3
Diatchenko, L.4
Zaykin, D.V.5
McHale, D.P.6
Drenth, J.P.7
Dai, F.8
Wheeler, J.9
Sanders, F.10
Wood, L.11
Wu, T.X.12
Karppinen, J.13
Nikolajsen, L.14
Männikkö, M.15
Max, M.B.16
Kiselycznyk, C.17
Poddar, M.18
Te Morsche, R.H.19
Smith, S.20
Gibson, D.21
Kelempisioti, A.22
Maixner, W.23
Gribble, F.M.24
Woods, C.G.25
more..
-
13
-
-
58149385667
-
Voltage-gated sodium channels: The search for subtype-selective analgesics
-
England S. Voltage-gated sodium channels: the search for subtype-selective analgesics. Expert Opin Investig Drugs 2008; 17: 1849-1864
-
(2008)
Expert Opin Investig Drugs
, vol.17
, pp. 1849-1864
-
-
England, S.1
-
14
-
-
0033694833
-
From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
-
Catterall WA. From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron 2000; 26: 13-25
-
(2000)
Neuron
, vol.26
, pp. 13-25
-
-
Catterall, W.A.1
-
15
-
-
79957823703
-
The study of sodium channels involved in pain responses using specific modulators
-
Ji YH, Liu T. The study of sodium channels involved in pain responses using specific modulators. Shengli Xuebao 2008; 60: 628-634
-
(2008)
Shengli Xuebao
, vol.60
, pp. 628-634
-
-
Ji, Y.H.1
Liu, T.2
-
16
-
-
55249124953
-
Sensory neuron voltage-gated sodium channels as analgesic drug targets
-
Momin A, Wood JN. Sensory neuron voltage-gated sodium channels as analgesic drug targets. Curr Opin Neurobiol 2008; 18: 383-388
-
(2008)
Curr Opin Neurobiol
, vol.18
, pp. 383-388
-
-
Momin, A.1
Wood, J.N.2
-
17
-
-
0034625139
-
Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses
-
Caldwell JH, Schaller KL, Lasher RS, Peles E, Levinson SR. Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses. Proc Natl Acad Sci USA 2000; 97: 5616-5620
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5616-5620
-
-
Caldwell, J.H.1
Schaller, K.L.2
Lasher, R.S.3
Peles, E.4
Levinson, S.R.5
-
18
-
-
0742305831
-
Colocalization of sodium channel Nav1.6 and the sodiumcalcium exchanger at sites of axonal injury in the spinal cord in EAE
-
Craner MJ, Hains BC, Lo AC, Black JA, Waxman SG. Colocalization of sodium channel Nav1.6 and the sodiumcalcium exchanger at sites of axonal injury in the spinal cord in EAE. Brain 2004; 127: 294-303
-
(2004)
Brain
, vol.127
, pp. 294-303
-
-
Craner, M.J.1
Hains, B.C.2
Lo, A.C.3
Black, J.A.4
Waxman, S.G.5
-
19
-
-
0037200807
-
Sodium channel Na(v)1.6 is expressed along nonmyelinated axons and it contributes to conduction
-
Black JA, Renganathan M, Waxman SG. Sodium channel Na(v)1.6 is expressed along nonmyelinated axons and it contributes to conduction. Brain Res Mol Brain Res 2002; 105: 19-28
-
(2002)
Brain Res Mol Brain Res
, vol.105
, pp. 19-28
-
-
Black, J.A.1
Renganathan, M.2
Waxman, S.G.3
-
20
-
-
50249127742
-
Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons
-
Fukuoka T, Kobayashi K, Yamanaka H, Obata K, Dai Y, Noguchi K. Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons. J Comp Neurol 2008; 510: 188-206
-
(2008)
J Comp Neurol
, vol.510
, pp. 188-206
-
-
Fukuoka, T.1
Kobayashi, K.2
Yamanaka, H.3
Obata, K.4
Dai, Y.5
Noguchi, K.6
-
21
-
-
73549084070
-
Sea anemone 'sting' isolates IB4-negative sensory neurones
-
Brock J. Sea anemone 'sting' isolates IB4-negative sensory neurones. J Physiol 2010; 588: 1143
-
(2010)
J Physiol
, vol.588
, pp. 1143
-
-
Brock, J.1
-
22
-
-
0027933696
-
Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy
-
Waxman SG, Kocsis JD, Black JA. Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy. J Neurophysiol 1994; 72: 466-470
-
(1994)
J Neurophysiol
, vol.72
, pp. 466-470
-
-
Waxman, S.G.1
Kocsis, J.D.2
Black, J.A.3
-
23
-
-
0031127498
-
Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): Different expression patterns in developing rat nervous system
-
Felts PA, Yokoyama S, Dib-Hajj S, Black JA, Waxman SG. Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system. Brain Res Mol Brain Res 1997; 45: 71-82
-
(1997)
Brain Res Mol Brain Res
, vol.45
, pp. 71-82
-
-
Felts, P.A.1
Yokoyama, S.2
Dib-Hajj, S.3
Black, J.A.4
Waxman, S.G.5
-
24
-
-
0035882467
-
De-velopmental expression of the TTX-resistant voltage-gated sodium channels Nav1.8 (SNS) and Nav1.9 (SNS2) in primary sensory neurons
-
Benn SC, Costigan M, Tate S, Fitzgerald M, Woolf CJ. De-velopmental expression of the TTX-resistant voltage-gated sodium channels Nav1.8 (SNS) and Nav1.9 (SNS2) in primary sensory neurons. J Neurosci 2001; 21: 6077-6085
-
(2001)
J Neurosci
, vol.21
, pp. 6077-6085
-
-
Benn, S.C.1
Costigan, M.2
Tate, S.3
Fitzgerald, M.4
Woolf, C.J.5
-
25
-
-
28844448678
-
Relationship between sodium channel Nav1.3 expression and neuropathic pain behavior in rats
-
Lindia JA, Köhler MG, Martin WJ, Abbadie C. Relationship between sodium channel Nav1.3 expression and neuropathic pain behavior in rats. Pain 2005; 117: 145-153
-
(2005)
Pain
, vol.117
, pp. 145-153
-
-
Lindia, J.A.1
Köhler, M.G.2
Martin, W.J.3
Abbadie, C.4
-
26
-
-
49249100212
-
Novel mRNA isoforms of the sodium channels Na(v)1.2, Na(v)1.3 and Na(v)1.7 encode predicted two-domain, truncated proteins
-
Kerr NC, Holmes FE, Wynick D. Novel mRNA isoforms of the sodium channels Na(v)1.2, Na(v)1.3 and Na(v)1.7 encode predicted two-domain, truncated proteins. Neuroscience 2008; 155: 797-808
-
(2008)
Neuroscience
, vol.155
, pp. 797-808
-
-
Kerr, N.C.1
Holmes, F.E.2
Wynick, D.3
-
27
-
-
0026625864
-
The glial voltage-gated sodium channel: Cell- and tissue-specific mRNA expression
-
Gautron S, Dos Santos G, Pinto-Henrique D, Koulakoff A, Gros F, Berwald-Netter Y. The glial voltage-gated sodium channel: cell- and tissue-specific mRNA expression. Proc Natl Acad Sci USA 1992; 89: 7272-7276
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7272-7276
-
-
Gautron, S.1
dos Santos, G.2
Pinto-Henrique, D.3
Koulakoff, A.4
Gros, F.5
Berwald-Netter, Y.6
-
28
-
-
0031282379
-
NaG: A sodium channel-like mRNA shared by Schwann cells and other neural crest derivatives
-
Felts PA, Black JA, Dib-Hajj SD, Waxman SG. NaG: a sodium channel-like mRNA shared by Schwann cells and other neural crest derivatives. Glia 1997; 21: 269-276
-
(1997)
Glia
, vol.21
, pp. 269-276
-
-
Felts, P.A.1
Black, J.A.2
Dib-Hajj, S.D.3
Waxman, S.G.4
-
29
-
-
59449091153
-
Sodium channel mutation in irritable bowel syndrome: Evidence for an ion channelopathy
-
Saito YA, Strege PR, Tester DJ, Locke GR 3rd, Talley NJ, Bernard CE, Rae JL, Makielski JC, Ackerman MJ, Farrugia G. Sodium channel mutation in irritable bowel syndrome: evidence for an ion channelopathy. Am J Physiol Gastrointest Liver Physiol 2009; 296: G211-G218
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
-
-
Saito, Y.A.1
Strege, P.R.2
Tester, D.J.3
Locke III, G.R.4
Talley, N.J.5
Bernard, C.E.6
Rae, J.L.7
Makielski, J.C.8
Ackerman, M.J.9
Farrugia, G.10
-
30
-
-
23444433183
-
Intrarectal lidocaine is an effective treatment for abdominal pain associated with diarrheapredominant irritable bowel syndrome
-
Verne GN, Sen A, Price DD. Intrarectal lidocaine is an effective treatment for abdominal pain associated with diarrheapredominant irritable bowel syndrome. J Pain 2005; 6: 493-496
-
(2005)
J Pain
, vol.6
, pp. 493-496
-
-
Verne, G.N.1
Sen, A.2
Price, D.D.3
-
31
-
-
35448950791
-
Voltage-gated ion channel Nav1.7 innervation in patients with idiopathic rectal hypersensitivity and paroxysmal extreme pain disorder (familial rectal pain)
-
Yiangou Y, Facer P, Chessell IP, Bountra C, Chan C, Fertleman C, Smith V, Anand P. Voltage-gated ion channel Nav1.7 innervation in patients with idiopathic rectal hypersensitivity and paroxysmal extreme pain disorder (familial rectal pain). Neurosci Lett 2007; 427: 77-82
-
(2007)
Neurosci Lett
, vol.427
, pp. 77-82
-
-
Yiangou, Y.1
Facer, P.2
Chessell, I.P.3
Bountra, C.4
Chan, C.5
Fertleman, C.6
Smith, V.7
Anand, P.8
-
32
-
-
0035503586
-
The involvement of the tetrodotoxin-resistant sodium channel Na(v)1.8 (PN3/SNS) in a rat model of visceral pain
-
Yoshimura N, Seki S, Novakovic SD, Tzoumaka E, Erickson VL, Erickson KA, Chancellor MB, de Groat WC. The involvement of the tetrodotoxin-resistant sodium channel Na(v)1.8 (PN3/SNS) in a rat model of visceral pain. J Neurosci 2001; 21: 8690-8696
-
(2001)
J Neurosci
, vol.21
, pp. 8690-8696
-
-
Yoshimura, N.1
Seki, S.2
Novakovic, S.D.3
Tzoumaka, E.4
Erickson, V.L.5
Erickson, K.A.6
Chancellor, M.B.7
de Groat, W.C.8
-
33
-
-
33750953325
-
Bladder overactivity and hyperexcitability of bladder afferent neurons after intrathecal delivery of nerve growth factor in rats
-
Yoshimura N, Bennett NE, Hayashi Y, Ogawa T, Nishizawa O, Chancellor MB, de Groat WC, Seki S. Bladder overactivity and hyperexcitability of bladder afferent neurons after intrathecal delivery of nerve growth factor in rats. J Neurosci 2006; 26: 10847-10855
-
(2006)
J Neurosci
, vol.26
, pp. 10847-10855
-
-
Yoshimura, N.1
Bennett, N.E.2
Hayashi, Y.3
Ogawa, T.4
Nishizawa, O.5
Chancellor, M.B.6
de Groat, W.C.7
Seki, S.8
-
34
-
-
17644411712
-
Differential responses of bladder lumbosacral and thoracolumbar dorsal root ganglion neurons to purinergic agonists, protons, and capsaicin
-
Dang K, Bielefeldt K, Gebhart GF. Differential responses of bladder lumbosacral and thoracolumbar dorsal root ganglion neurons to purinergic agonists, protons, and capsaicin. J Neurosci 2005; 25: 3973-3984
-
(2005)
J Neurosci
, vol.25
, pp. 3973-3984
-
-
Dang, K.1
Bielefeldt, K.2
Gebhart, G.F.3
-
35
-
-
4644290610
-
Two TTX-resistant Na+ currents in mouse colonic dorsal root ganglia neurons and their role in colitis-induced hyperexcitability
-
Beyak MJ, Ramji N, Krol KM, Kawaja MD, Vanner SJ. Two TTX-resistant Na+ currents in mouse colonic dorsal root ganglia neurons and their role in colitis-induced hyperexcitability. Am J Physiol Gastrointest Liver Physiol 2004; 287: G845-G855
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
-
-
Beyak, M.J.1
Ramji, N.2
Krol, K.M.3
Kawaja, M.D.4
Vanner, S.J.5
-
36
-
-
0242475152
-
Ileitis modulates potassium and sodium currents in guinea pig dorsal root ganglia sensory neurons
-
Stewart T, Beyak MJ, Vanner S. Ileitis modulates potassium and sodium currents in guinea pig dorsal root ganglia sensory neurons. J Physiol 2003; 552: 797-807
-
(2003)
J Physiol
, vol.552
, pp. 797-807
-
-
Stewart, T.1
Beyak, M.J.2
Vanner, S.3
-
37
-
-
68249133724
-
Trinitrobenzenesulphonic acid colitis alters Na 1.8 channel expression in mouse dorsal root ganglia neurons
-
King DE, Macleod RJ, Vanner SJ. Trinitrobenzenesulphonic acid colitis alters Na 1.8 channel expression in mouse dorsal root ganglia neurons. Neurogastroenterol Motil 2009; 21: 880-e64
-
(2009)
Neurogastroenterol Motil
, vol.21
-
-
King, D.E.1
Macleod, R.J.2
Vanner, S.J.3
-
38
-
-
0036293655
-
Gastric hyperalgesia and changes in voltage gated sodium channel function in the rat
-
Gebhart GF, Bielefeldt K, Ozaki N. Gastric hyperalgesia and changes in voltage gated sodium channel function in the rat. Gut 2002; 51 Suppl 1: i15-i18
-
(2002)
Gut
, vol.51
, Issue.SUPPL. 1
-
-
Gebhart, G.F.1
Bielefeldt, K.2
Ozaki, N.3
-
39
-
-
33748302122
-
Enhanced excitability and suppression of A-type K+ current of pancreas-specific afferent neurons in a rat model of chronic pancreatitis
-
Xu GY, Winston JH, Shenoy M, Yin H, Pasricha PJ. Enhanced excitability and suppression of A-type K+ current of pancreas-specific afferent neurons in a rat model of chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol 2006; 291: G424-G431
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.291
-
-
Xu, G.Y.1
Winston, J.H.2
Shenoy, M.3
Yin, H.4
Pasricha, P.J.5
-
40
-
-
33748888226
-
Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Nav1.8 and Nav1.9 null mice
-
Hillsley K, Lin JH, Stanisz A, Grundy D, Aerssens J, Peeters PJ, Moechars D, Coulie B, Stead RH. Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Nav1.8 and Nav1.9 null mice. J Physiol 2006; 576: 257-267
-
(2006)
J Physiol
, vol.576
, pp. 257-267
-
-
Hillsley, K.1
Lin, J.H.2
Stanisz, A.3
Grundy, D.4
Aerssens, J.5
Peeters, P.J.6
Moechars, D.7
Coulie, B.8
Stead, R.H.9
-
41
-
-
0036813714
-
Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)- null mice
-
Laird JM, Souslova V, Wood JN, Cervero F. Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)- null mice. J Neurosci 2002; 22: 8352-8356
-
(2002)
J Neurosci
, vol.22
, pp. 8352-8356
-
-
Laird, J.M.1
Souslova, V.2
Wood, J.N.3
Cervero, F.4
-
42
-
-
48349142882
-
Lack of colonic-inflammation-induced acute visceral hypersensitivity to colorectal distension in Na(v)1.9 knockout mice
-
Martinez V, Melgar S. Lack of colonic-inflammation-induced acute visceral hypersensitivity to colorectal distension in Na(v)1.9 knockout mice. Eur J Pain 2008; 12: 934-944
-
(2008)
Eur J Pain
, vol.12
, pp. 934-944
-
-
Martinez, V.1
Melgar, S.2
-
43
-
-
59349110748
-
The voltage-gated sodium channel Nav1.9 is required for inflammation-based urinary bladder dysfunction
-
Ritter AM, Martin WJ, Thorneloe KS. The voltage-gated sodium channel Nav1.9 is required for inflammation-based urinary bladder dysfunction. Neurosci Lett 2009; 452: 28-32
-
(2009)
Neurosci Lett
, vol.452
, pp. 28-32
-
-
Ritter, A.M.1
Martin, W.J.2
Thorneloe, K.S.3
-
44
-
-
50649098689
-
Blockade of NGF and trk receptors inhibits increased peripheral mechanical sensitivity accompanying cystitis in rats
-
Guerios SD, Wang ZY, Boldon K, Bushman W, Bjorling DE. Blockade of NGF and trk receptors inhibits increased peripheral mechanical sensitivity accompanying cystitis in rats. Am J Physiol Regul Integr Comp Physiol 2008; 295: R111-R122
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.295
-
-
Guerios, S.D.1
Wang, Z.Y.2
Boldon, K.3
Bushman, W.4
Bjorling, D.E.5
-
45
-
-
0036712354
-
Prostaglandin E(2) modulates TTX-R I(Na) in rat colonic sensory neurons
-
Gold MS, Zhang L, Wrigley DL, Traub RJ. Prostaglandin E(2) modulates TTX-R I(Na) in rat colonic sensory neurons. J Neurophysiol 2002; 88: 1512-1522
-
(2002)
J Neurophysiol
, vol.88
, pp. 1512-1522
-
-
Gold, M.S.1
Zhang, L.2
Wrigley, D.L.3
Traub, R.J.4
-
46
-
-
43049116097
-
TTX-R Na+ current-reduction by celecoxib correlates with changes in PGE(2) and CGRP within rat DRG neurons during acute incisional pain
-
Ma K, Zhou QH, Chen J, Du DP, Ji Y, Jiang W. TTX-R Na+ current-reduction by celecoxib correlates with changes in PGE(2) and CGRP within rat DRG neurons during acute incisional pain. Brain Res 2008; 1209: 57-64
-
(2008)
Brain Res
, vol.1209
, pp. 57-64
-
-
Ma, K.1
Zhou, Q.H.2
Chen, J.3
Du, D.P.4
Ji, Y.5
Jiang, W.6
-
47
-
-
40849083674
-
Inflammatory mediators increase Nav1.9 current and excitability in nociceptors through a coincident detection mechanism
-
Maingret F, Coste B, Padilla F, Clerc N, Crest M, Korogod SM, Delmas P. Inflammatory mediators increase Nav1.9 current and excitability in nociceptors through a coincident detection mechanism. J Gen Physiol 2008; 131: 211-225
-
(2008)
J Gen Physiol
, vol.131
, pp. 211-225
-
-
Maingret, F.1
Coste, B.2
Padilla, F.3
Clerc, N.4
Crest, M.5
Korogod, S.M.6
Delmas, P.7
-
48
-
-
77949327897
-
Aquaporin-1 tunes pain perception by interaction with Na(v)1.8 Na+ channels in dorsal root ganglion neurons
-
Zhang H, Verkman AS. Aquaporin-1 tunes pain perception by interaction with Na(v)1.8 Na+ channels in dorsal root ganglion neurons. J Biol Chem 2010; 285: 5896-5906
-
(2010)
J Biol Chem
, vol.285
, pp. 5896-5906
-
-
Zhang, H.1
Verkman, A.S.2
-
49
-
-
58149387593
-
Nociceptors are interleukin-1beta sensors
-
Binshtok AM, Wang H, Zimmermann K, Amaya F, Vardeh D, Shi L, Brenner GJ, Ji RR, Bean BP, Woolf CJ, Samad TA. Nociceptors are interleukin-1beta sensors. J Neurosci 2008; 28: 14062-14073
-
(2008)
J Neurosci
, vol.28
, pp. 14062-14073
-
-
Binshtok, A.M.1
Wang, H.2
Zimmermann, K.3
Amaya, F.4
Vardeh, D.5
Shi, L.6
Brenner, G.J.7
Ji, R.R.8
Bean, B.P.9
Woolf, C.J.10
Samad, T.A.11
-
50
-
-
69549118509
-
The endogenous hydrogen sulfide producing enzyme cystathionine-beta synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome
-
Xu GY, Winston JH, Shenoy M, Zhou S, Chen JD, Pasricha PJ. The endogenous hydrogen sulfide producing enzyme cystathionine-beta synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome. Mol Pain 2009; 5: 44
-
(2009)
Mol Pain
, vol.5
, pp. 44
-
-
Xu, G.Y.1
Winston, J.H.2
Shenoy, M.3
Zhou, S.4
Chen, J.D.5
Pasricha, P.J.6
-
51
-
-
76149104939
-
ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties
-
Stamboulian S, Choi JS, Ahn HS, Chang YW, Tyrrell L, Black JA, Waxman SG, Dib-Hajj SD. ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties. J Neurosci 2010; 30: 1637-1647
-
(2010)
J Neurosci
, vol.30
, pp. 1637-1647
-
-
Stamboulian, S.1
Choi, J.S.2
Ahn, H.S.3
Chang, Y.W.4
Tyrrell, L.5
Black, J.A.6
Waxman, S.G.7
Dib-Hajj, S.D.8
-
52
-
-
59749090393
-
The peripheral pro-nociceptive state induced by repetitive inflammatory stimuli involves continuous activation of protein kinase A and protein kinase C epsilon and its Na(V)1.8 sodium channel functional regulation in the primary sensory neuron
-
Villarreal CF, Sachs D, Funez MI, Parada CA, de Queiroz Cunha F, Ferreira SH. The peripheral pro-nociceptive state induced by repetitive inflammatory stimuli involves continuous activation of protein kinase A and protein kinase C epsilon and its Na(V)1.8 sodium channel functional regulation in the primary sensory neuron. Biochem Pharmacol 2009; 77: 867-877
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 867-877
-
-
Villarreal, C.F.1
Sachs, D.2
Funez, M.I.3
Parada, C.A.4
de Queiroz Cunha, F.5
Ferreira, S.H.6
-
53
-
-
33745737497
-
Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons
-
Choi JS, Hudmon A, Waxman SG, Dib-Hajj SD. Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons. J Neurophysiol 2006; 96: 97-108
-
(2006)
J Neurophysiol
, vol.96
, pp. 97-108
-
-
Choi, J.S.1
Hudmon, A.2
Waxman, S.G.3
Dib-Hajj, S.D.4
-
54
-
-
66449112479
-
Voltage-gated sodium channel blockers for the treatment of chronic pain
-
Matulenko MA, Scanio MJ, Kort ME. Voltage-gated sodium channel blockers for the treatment of chronic pain. Curr Top Med Chem 2009; 9: 362-376
-
(2009)
Curr Top Med Chem
, vol.9
, pp. 362-376
-
-
Matulenko, M.A.1
Scanio, M.J.2
Kort, M.E.3
-
56
-
-
72049087523
-
Targeting voltage-gated sodium channels for pain therapy
-
Clare JJ. Targeting voltage-gated sodium channels for pain therapy. Expert Opin Investig Drugs 2010; 19: 45-62
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 45-62
-
-
Clare, J.J.1
-
58
-
-
0026321760
-
Caffeineinduced block of Na+ current in guinea pig single ventricular cells
-
Habuchi Y, Tanaka H, Furukawa T, Tsujimura Y. Caffeineinduced block of Na+ current in guinea pig single ventricular cells. Am J Physiol 1991; 261: H1855-H1863
-
(1991)
Am J Physiol
, vol.261
-
-
Habuchi, Y.1
Tanaka, H.2
Furukawa, T.3
Tsujimura, Y.4
-
59
-
-
34347213786
-
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat
-
Jarvis MF, Honore P, Shieh CC, Chapman M, Joshi S, Zhang XF, Kort M, Carroll W, Marron B, Atkinson R, Thomas J, Liu D, Krambis M, Liu Y, McGaraughty S, Chu K, Roeloffs R, Zhong C, Mikusa JP, Hernandez G, Gauvin D, Wade C, Zhu C, Pai M, Scanio M, Shi L, Drizin I, Gregg R, Matulenko M, Hakeem A, Gross M, Johnson M, Marsh K, Wagoner PK, Sullivan JP, Faltynek CR, Krafte DS. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci USA 2007; 104: 8520-8525
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 8520-8525
-
-
Jarvis, M.F.1
Honore, P.2
Shieh, C.C.3
Chapman, M.4
Joshi, S.5
Zhang, X.F.6
Kort, M.7
Carroll, W.8
Marron, B.9
Atkinson, R.10
Thomas, J.11
Liu, D.12
Krambis, M.13
Liu, Y.14
McGaraughty, S.15
Chu, K.16
Roeloffs, R.17
Zhong, C.18
Mikusa, J.P.19
Hernandez, G.20
Gauvin, D.21
Wade, C.22
Zhu, C.23
Pai, M.24
Scanio, M.25
Shi, L.26
Drizin, I.27
Gregg, R.28
Matulenko, M.29
Hakeem, A.30
Gross, M.31
Johnson, M.32
Marsh, K.33
Wagoner, P.K.34
Sullivan, J.P.35
Faltynek, C.R.36
Krafte, D.S.37
more..
-
60
-
-
27744521224
-
Ambroxol, a Nav1.8- preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain
-
Gaida W, Klinder K, Arndt K, Weiser T. Ambroxol, a Nav1.8- preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain. Neuropharmacology 2005; 49: 1220-1227
-
(2005)
Neuropharmacology
, vol.49
, pp. 1220-1227
-
-
Gaida, W.1
Klinder, K.2
Arndt, K.3
Weiser, T.4
-
61
-
-
0036707535
-
Pregabalin (CI-1008) inhibits the trinitrobenzene sulfonic acid-induced chronic colonic allodynia in the rat
-
Diop L, Raymond F, Fargeau H, Petoux F, Chovet M, Doherty AM. Pregabalin (CI-1008) inhibits the trinitrobenzene sulfonic acid-induced chronic colonic allodynia in the rat. J Pharmacol Exp Ther 2002; 302: 1013-1022
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 1013-1022
-
-
Diop, L.1
Raymond, F.2
Fargeau, H.3
Petoux, F.4
Chovet, M.5
Doherty, A.M.6
-
62
-
-
34548127061
-
Effect of a second-generation alpha2delta ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome
-
Houghton LA, Fell C, Whorwell PJ, Jones I, Sudworth DP, Gale JD. Effect of a second-generation alpha2delta ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome. Gut 2007; 56: 1218-1225
-
(2007)
Gut
, vol.56
, pp. 1218-1225
-
-
Houghton, L.A.1
Fell, C.2
Whorwell, P.J.3
Jones, I.4
Sudworth, D.P.5
Gale, J.D.6
-
65
-
-
77953262644
-
Mu-conotoxin KIIIA derivatives with divergent affinities versus efficacies in blocking voltage-gated sodium channels
-
Zhang MM, Han TS, Olivera BM, Bulaj G, Yoshikami D. Mu-conotoxin KIIIA derivatives with divergent affinities versus efficacies in blocking voltage-gated sodium channels. Biochemistry 2010; 49: 4804-4812
-
(2010)
Biochemistry
, vol.49
, pp. 4804-4812
-
-
Zhang, M.M.1
Han, T.S.2
Olivera, B.M.3
Bulaj, G.4
Yoshikami, D.5
-
66
-
-
33845901486
-
An SCN9A channelopathy causes congenital inability to experience pain
-
Cox JJ, Reimann F, Nicholas AK, Thornton G, Roberts E, Springell K, Karbani G, Jafri H, Mannan J, Raashid Y, Al-Gazali L, Hamamy H, Valente EM, Gorman S, Williams R, McHale DP, Wood JN, Gribble FM, Woods CG. An SCN9A channelopathy causes congenital inability to experience pain. Nature 2006; 444: 894-988
-
(2006)
Nature
, vol.444
, pp. 894-988
-
-
Cox, J.J.1
Reimann, F.2
Nicholas, A.K.3
Thornton, G.4
Roberts, E.5
Springell, K.6
Karbani, G.7
Jafri, H.8
Mannan, J.9
Raashid, Y.10
Al-Gazali, L.11
Hamamy, H.12
Valente, E.M.13
Gorman, S.14
Williams, R.15
McHale, D.P.16
Wood, J.N.17
Gribble, F.M.18
Woods, C.G.19
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