Nicotine increases the VEGF/PEDF ratio in retinal pigment Epithelium: A possible mechanism for CNV in passive smokers with AMD

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 6, 2011, Pages 3842-3853

  Pons, Marianne ^a   Marin Castaño, Maria E ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEXAMETHONIUM; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINE; NICOTINIC RECEPTOR; PIGMENT EPITHELIUM DERIVED FACTOR; VASCULOTROPIN; EYE PROTEIN; NERVE GROWTH FACTOR; NICOTINIC RECEPTOR BLOCKING AGENT; PIGMENT EPITHELIUM-DERIVED FACTOR; SERINE PROTEINASE INHIBITOR; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

AGED; ANIMAL CELL; ARTICLE; CELL COUNT; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; MALE; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA MACULA AGE RELATED DEGENERATION; SMOKING; SUBRETINAL NEOVASCULARIZATION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; DRUG EFFECT; EXUDATIVE MACULAR DEGENERATION; METABOLISM; PASSIVE SMOKING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ANIMALS; BLOTTING, WESTERN; CELL DEATH; CELL PROLIFERATION; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; EYE PROTEINS; HEXAMETHONIUM; HUMANS; MALE; NERVE GROWTH FACTORS; NICOTINE; NICOTINIC ANTAGONISTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERPINS; TOBACCO SMOKE POLLUTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WET MACULAR DEGENERATION;

EID: 79957746980     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-6254     Document Type: Article

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