-
1
-
-
11144354339
-
Prevalence of age-related macular degeneration in the United States
-
Friedman DS, O'Colmain BJ, Munoz B, Tomany SC, McCarty C, et al. (2004) Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 122: 564-572.
-
(2004)
Arch Ophthalmol
, vol.122
, pp. 564-572
-
-
Friedman, D.S.1
O'Colmain, B.J.2
Munoz, B.3
Tomany, S.C.4
McCarty, C.5
-
2
-
-
29744442338
-
Smoking and age related macular degeneration: The number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation
-
Khan JC, Thurlby DA, Shahid H, Clayton DG, Yates JR, et al. (2006) Smoking and age related macular degeneration: the number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation. Br J Ophthalmol 90: 75-80.
-
(2006)
Br J Ophthalmol
, vol.90
, pp. 75-80
-
-
Khan, J.C.1
Thurlby, D.A.2
Shahid, H.3
Clayton, D.G.4
Yates, J.R.5
-
3
-
-
30944437438
-
Smoking and age-related macular degeneration: A review of association
-
Thornton J, Edwards R, Mitchell P, Harrison RA, Buchan I, et al. (2005) Smoking and age-related macular degeneration: a review of association. Eye 19: 935-944.
-
(2005)
Eye
, vol.19
, pp. 935-944
-
-
Thornton, J.1
Edwards, R.2
Mitchell, P.3
Harrison, R.A.4
Buchan, I.5
-
4
-
-
3042662037
-
Risk factors for incident age-related macular degeneration: Pooled findings from 3 continents
-
Tomany SC, Wang JJ, Van Leeuwen R, Klein R, Mitchell P, et al. (2004) Risk factors for incident age-related macular degeneration: pooled findings from 3 continents. Ophthalmology 111: 1280-1287.
-
(2004)
Ophthalmology
, vol.111
, pp. 1280-1287
-
-
Tomany, S.C.1
Wang, J.J.2
Van Leeuwen, R.3
Klein, R.4
Mitchell, P.5
-
5
-
-
16244368037
-
Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19
-
Clemons TE, Milton RC, Klein R, Seddon JM, Ferris FL III (2005) Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19. Ophthalmology 112: 533-539.
-
(2005)
Ophthalmology
, vol.112
, pp. 533-539
-
-
Clemons, T.E.1
Milton, R.C.2
Klein, R.3
Seddon, J.M.4
Ferris III, F.L.5
-
6
-
-
17644406331
-
28,000 Cases of age related macular degeneration causing visual loss in people aged 75 years and above in the United Kingdom may be attributable to smoking
-
Evans JR, Fletcher AE, Wormald RP (2005) 28,000 Cases of age related macular degeneration causing visual loss in people aged 75 years and above in the United Kingdom may be attributable to smoking. Br J Ophthalmol 89: 550-553.
-
(2005)
Br J Ophthalmol
, vol.89
, pp. 550-553
-
-
Evans, J.R.1
Fletcher, A.E.2
Wormald, R.P.3
-
7
-
-
27744462212
-
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
-
Rivera A, Fisher SA, Fritsche LG, Keilhauer CN, Lichtner P, et al. (2005) Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet 14: 3227-3236.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3227-3236
-
-
Rivera, A.1
Fisher, S.A.2
Fritsche, L.G.3
Keilhauer, C.N.4
Lichtner, P.5
-
8
-
-
46249098503
-
Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA
-
Fritsche LG, Loenhardt T, Janssen A, Fisher SA, Rivera A, et al. (2008) Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA. Nat Genet 40: 892-896.
-
(2008)
Nat Genet
, vol.40
, pp. 892-896
-
-
Fritsche, L.G.1
Loenhardt, T.2
Janssen, A.3
Fisher, S.A.4
Rivera, A.5
-
9
-
-
36049042661
-
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
-
Kanda A, Chen W, Othman M, Branham KE, Brooks M, et al. (2007) A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci U S A 104: 16227-16232.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 16227-16232
-
-
Kanda, A.1
Chen, W.2
Othman, M.3
Branham, K.E.4
Brooks, M.5
-
10
-
-
33646070308
-
Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration
-
Schmidt S, Hauser MA, Scott WK, Postel EA, Agarwal A, et al. (2006) Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. Am J Hum Genet 78: 852-864.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 852-864
-
-
Schmidt, S.1
Hauser, M.A.2
Scott, W.K.3
Postel, E.A.4
Agarwal, A.5
-
11
-
-
47749106479
-
-
PLoS
-
Canter JA, Olson LM, Spencer K, Schnetz-Boutaud N, Anderson B, et al. (2008) Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration. PLoS ONE 3: e2091.
-
(2008)
Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration
, vol.ONE 3
-
-
Canter, J.A.1
Olson, L.M.2
Spencer, K.3
Schnetz-Boutaud, N.4
Anderson, B.5
-
12
-
-
0034533059
-
Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration
-
Kimura K, Isashiki Y, Sonoda S, Kakiuchi-Matsumoto T, Ohba N (2000) Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration. Am J Ophthalmol 130: 769-773.
-
(2000)
Am J Ophthalmol
, vol.130
, pp. 769-773
-
-
Kimura, K.1
Isashiki, Y.2
Sonoda, S.3
Kakiuchi-Matsumoto, T.4
Ohba, N.5
-
13
-
-
0020431144
-
-
Conney AH (1982) Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture. Cancer Res 42: 4875-4917.
-
Conney AH (1982) Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture. Cancer Res 42: 4875-4917.
-
-
-
-
14
-
-
0019306621
-
Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo [a]pyrene
-
Backer JM, Weinstein IB (1980) Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo [a]pyrene. Science 209: 297-299.
-
(1980)
Science
, vol.209
, pp. 297-299
-
-
Backer, J.M.1
Weinstein, I.B.2
-
15
-
-
0036315408
-
Retinal pigment epithelial cell DNA is damaged by exposure to benzo[a]pyrene, a constituent of cigarette smoke
-
Patton WP, Routledge MN, Jones GD, Lewis SE, Archer DB, et al. (2002) Retinal pigment epithelial cell DNA is damaged by exposure to benzo[a]pyrene, a constituent of cigarette smoke. Exp Eye Res 74: 513-522.
-
(2002)
Exp Eye Res
, vol.74
, pp. 513-522
-
-
Patton, W.P.1
Routledge, M.N.2
Jones, G.D.3
Lewis, S.E.4
Archer, D.B.5
-
16
-
-
41949092130
-
Increased mitochondrial DNA damage and down-regulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid
-
Wang AL, Lukas TJ, Yuan M, Neufeld AH (2008) Increased mitochondrial DNA damage and down-regulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid. Mol Vis 14: 644-651.
-
(2008)
Mol Vis
, vol.14
, pp. 644-651
-
-
Wang, A.L.1
Lukas, T.J.2
Yuan, M.3
Neufeld, A.H.4
-
17
-
-
58349109733
-
-
PLoS ONE
-
Wang AL, Lukas TJ, Yuan M, Du N, Tso MO, et al. (2008) Autophagy and exosomes in the aged retinal pigment epithelium: Possible relevance to drusen formation and age-related macular degeneration. PLoS ONE.
-
(2008)
Autophagy and exosomes in the aged retinal pigment epithelium: Possible relevance to drusen formation and age-related macular degeneration
-
-
Wang, A.L.1
Lukas, T.J.2
Yuan, M.3
Du, N.4
Tso, M.O.5
-
18
-
-
0029872876
-
ARPE-19, a human retinal pigment epithelial cell line with differentiated properties
-
Dunn KC, otaki-Keen AE, Putkey FR, Hjelmeland LM (1996) ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res 62: 155-169.
-
(1996)
Exp Eye Res
, vol.62
, pp. 155-169
-
-
Dunn, K.C.1
otaki-Keen, A.E.2
Putkey, F.R.3
Hjelmeland, L.M.4
-
19
-
-
0029872876
-
ARPE-19, a human retinal pigment epithelial cell line with differentiated properties
-
Dunn KC, Aotaki-Keen AE, Putkey FR, Hjelmeland LM (1996) ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res 62: 155-169.
-
(1996)
Exp Eye Res
, vol.62
, pp. 155-169
-
-
Dunn, K.C.1
Aotaki-Keen, A.E.2
Putkey, F.R.3
Hjelmeland, L.M.4
-
20
-
-
0023064180
-
Peripherin. A rim-specific membrane protein of rod outer segment discs
-
Molday RS, Hicks D, Molday L (1987) Peripherin. A rim-specific membrane protein of rod outer segment discs. Invest Ophthalmol Vis Sci 28: 50-61.
-
(1987)
Invest Ophthalmol Vis Sci
, vol.28
, pp. 50-61
-
-
Molday, R.S.1
Hicks, D.2
Molday, L.3
-
21
-
-
0033588898
-
Macrophage and retinal pigment epithelium phagocytosis: Apoptotic cells and photoreceptors compete for alphavbeta3 and alphavbeta5 integrins, and protein kinase C regulates alphavbeta5 binding and cytoskeletal linkage
-
Finnemann SC, Rodriguez-Boulan E (1999) Macrophage and retinal pigment epithelium phagocytosis: apoptotic cells and photoreceptors compete for alphavbeta3 and alphavbeta5 integrins, and protein kinase C regulates alphavbeta5 binding and cytoskeletal linkage. J Exp Med 190: 861-874.
-
(1999)
J Exp Med
, vol.190
, pp. 861-874
-
-
Finnemann, S.C.1
Rodriguez-Boulan, E.2
-
22
-
-
64049111816
-
-
Chen H, Lukas TJ, Du N, Suyeoka G, Neufeld AH (2009) Dysfunction of the retinal pigment epithelium with age: increased iron decreases phagocytosis and lysosomal activity. Invest Ophthalmol Vis Sci.
-
Chen H, Lukas TJ, Du N, Suyeoka G, Neufeld AH (2009) Dysfunction of the retinal pigment epithelium with age: increased iron decreases phagocytosis and lysosomal activity. Invest Ophthalmol Vis Sci.
-
-
-
-
23
-
-
0029921379
-
Age-related changes of glycosidases in human retinal pigment epithelium
-
Cingle KA, Kalski RS, Bruner WE, O'Brien CM, Erhard P, et al. (1996) Age-related changes of glycosidases in human retinal pigment epithelium. Curr Eye Res 15: 433-438.
-
(1996)
Curr Eye Res
, vol.15
, pp. 433-438
-
-
Cingle, K.A.1
Kalski, R.S.2
Bruner, W.E.3
O'Brien, C.M.4
Erhard, P.5
-
24
-
-
52349098746
-
-
PLoS
-
Fujihara M, Nagai N, Sussan TE, Biswal S, Handa JT (2008) Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice. PLoS ONE 3: e3119.
-
(2008)
Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice
, vol.ONE 3
-
-
Fujihara, M.1
Nagai, N.2
Sussan, T.E.3
Biswal, S.4
Handa, J.T.5
-
26
-
-
34948874257
-
Tetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosis
-
Chang Y, Finnemann SC (2007) Tetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosis. J Cell Sci 120: 3053-3063.
-
(2007)
J Cell Sci
, vol.120
, pp. 3053-3063
-
-
Chang, Y.1
Finnemann, S.C.2
-
27
-
-
0032886890
-
Distribution of cathepsin D in human eyes with or without age-related maculopathy
-
Rakoczy PE, Sarks SH, Daw N, Constable IJ (1999) Distribution of cathepsin D in human eyes with or without age-related maculopathy. Exp Eye Res 69: 367-374.
-
(1999)
Exp Eye Res
, vol.69
, pp. 367-374
-
-
Rakoczy, P.E.1
Sarks, S.H.2
Daw, N.3
Constable, I.J.4
-
30
-
-
42549161012
-
Oxidized low density lipoproteins induce a pathologic response by retinal pigmented epithelial cells
-
Yamada Y, Tian J, Yang Y, Cutler RG, Wu T, et al. (2008) Oxidized low density lipoproteins induce a pathologic response by retinal pigmented epithelial cells. J Neurochem 105: 1187-1197.
-
(2008)
J Neurochem
, vol.105
, pp. 1187-1197
-
-
Yamada, Y.1
Tian, J.2
Yang, Y.3
Cutler, R.G.4
Wu, T.5
-
31
-
-
0036822469
-
Smoking and the 5-year incidence of age-related maculopathy: The Blue Mountains Eye Study
-
Mitchell P, Wang JJ, Smith W, Leeder SR (2002) Smoking and the 5-year incidence of age-related maculopathy: the Blue Mountains Eye Study. Arch Ophthalmol 120: 1357-1363.
-
(2002)
Arch Ophthalmol
, vol.120
, pp. 1357-1363
-
-
Mitchell, P.1
Wang, J.J.2
Smith, W.3
Leeder, S.R.4
-
32
-
-
38349056690
-
Further observations on the association between smoking and the long-term incidence and progression of age-related macular degeneration: The Beaver Dam Eye Study
-
Klein R, Knudtson MD, Cruickshanks KJ, Klein BE (2008) Further observations on the association between smoking and the long-term incidence and progression of age-related macular degeneration: the Beaver Dam Eye Study. Arch Ophthalmol 126: 115-121.
-
(2008)
Arch Ophthalmol
, vol.126
, pp. 115-121
-
-
Klein, R.1
Knudtson, M.D.2
Cruickshanks, K.J.3
Klein, B.E.4
-
33
-
-
0028081941
-
Regional variation and age-related changes of lysosomal enzymes in the human retinal pigment epithelium
-
Boulton M, Moriarty P, Jarvis-Evans J, Marcyniuk B (1994) Regional variation and age-related changes of lysosomal enzymes in the human retinal pigment epithelium. Br J Ophthalmol 78: 125-129.
-
(1994)
Br J Ophthalmol
, vol.78
, pp. 125-129
-
-
Boulton, M.1
Moriarty, P.2
Jarvis-Evans, J.3
Marcyniuk, B.4
-
34
-
-
0030876651
-
Age-related increase in activity of specific lysosomal enzymes in the human retinal pigment epithelium
-
Verdugo ME, Ray J (1997) Age-related increase in activity of specific lysosomal enzymes in the human retinal pigment epithelium. Exp Eye Res 65: 231-240.
-
(1997)
Exp Eye Res
, vol.65
, pp. 231-240
-
-
Verdugo, M.E.1
Ray, J.2
-
36
-
-
21044453724
-
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
-
Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, et al. (2005) A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A 102: 7227-7232.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 7227-7232
-
-
Hageman, G.S.1
Anderson, D.H.2
Johnson, L.V.3
Hancox, L.S.4
Taiber, A.J.5
-
37
-
-
33645419787
-
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
-
Gold B, Merriam JE, Zernant J, Hancox LS, Taiber AJ, et al. (2006) Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet 38: 458-462.
-
(2006)
Nat Genet
, vol.38
, pp. 458-462
-
-
Gold, B.1
Merriam, J.E.2
Zernant, J.3
Hancox, L.S.4
Taiber, A.J.5
|