Lysine mutagenesis identifies cationic charges of human CYP17 that interact with cytochrome b5 to promote male sex-hormone biosynthesis

Biochemical Journal

Volumn 342, Issue 2, 1999, Pages 309-312

  Lee Robichaud, Peter ^a   Akhtar, Monika E ^a   Akhtar, Muhammad ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

CYP17; Cytochrome b5; Mutagenesis; P450c17

Indexed keywords

ANDROGEN; CYTOCHROME B5; CYTOCHROME P450 ISOENZYME; LYASE; LYSINE; MUTANT PROTEIN;

AMINO ACID SUBSTITUTION; ANDROGEN SYNTHESIS; ARTICLE; CONTROLLED STUDY; HUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; ANDROGENS; BINDING SITES; CYTOCHROMES B5; HUMANS; KINETICS; LYSINE; MALE; MUTAGENESIS, SITE-DIRECTED; STEROID 17-ALPHA-HYDROXYLASE;

EID: 0033199862     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3420309     Document Type: Article

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