Crystallographic study on the dioxygen complex of wild-type and mutant cytochrome P450cam: Implications for the dioxygen activation mechanism

Journal of Biological Chemistry

Volumn 280, Issue 36, 2005, Pages 31659-31663

  Nagano, Shingo ^a,c   Poulos, Thomas L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RIKEN HARIMA INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; HYDROGEN BONDS; IRON; OXYGEN; PROTONS;

ACTIVATION MECHANISM; CYTOCHROME; DIOXYGEN; MUTANTS;

CRYSTALLOGRAPHY;

CAMPHOR 5 MONOOXYGENASE; CYTOCHROME P450; FERROUS DIOXYGEN; IRON COMPLEX; MUTANT PROTEIN; OXYGEN; UNCLASSIFIED DRUG;

ARTICLE; CRYSTALLIZATION; ESCHERICHIA COLI; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; CAMPHOR 5-MONOOXYGENASE; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; FERROUS COMPOUNDS; HYDROGEN BONDING; IRON; MUTATION; OXYGEN; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS PUTIDA;

EID: 24744459452     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M505261200     Document Type: Article

References (26)

1. Omura, T., and Sato, R. (1962) J. Biol. Chem. 237, 1375-1376
2. Ortiz de Montellano, P. R. (1995) Cytochrome P450: Structure, Mechanism, and Biochemistry, 2nd Ed., Plenum Press, New York
3. Katagiri, M., Ganguli, B. N., and Gunsalus, I. C. (1968) J. Biol. Chem. 243, 3543-3546
4. Gunsalus, I. C., and Wagner, G. C. (1978) Methods Enzymol. 52, 166-188
5. Haniu, M., Armes, L. G., Yasunobu, K. T., Shastry, B. A., and Gunsalus, I. C. (1982) J. Biol. Chem. 257, 12664-12671
6. Unger, B. P., Gunsalus, I. C., and Sligar, S. G. (1986) J. Biol. Chem. 261, 1158-1163
7. Poulos, T. L., Finzel, B. C., Gunsalus, I. C., Wagner, G. C., and Kraut, J. (1985) J. Biol. Chem. 260, 16122-16130
8. Ishimura, Y., Ullrich, V., and Peterson, J. A. (1971) Biochem. Biophys. Res. Commun. 42, 140-146
9. Davydov, R., Macdonald, I. D. G., Makris, T. M., Sligar, S. G., and Hoffman, B. M. (1999) J. Am. Chem. Soc. 121, 10654-10655
10. Davydov, R., Makris, T. M., Kofman, V., Werst, D. E., Sligar, S. G., and Hoffman, B. M. (2001) J. Am. Chem. Soc. 123, 1403-1415
11. Imai, M., Shimada, H., Watanabe, Y., Matsushima-Hibiya, Y., Makino, R., Koga, H., Horiuchi, T., and Ishimura, Y. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 7823-7827
12. Martinis, S. A., Atkins, W. M., Stayton, P. S., and Sligar, S. G. (1989) J. Am. Chem. Soc. 111, 9252-9253
13. Shimada, H., Makino, R., Imai, M., Horiuchi, T., and Ishimura, Y. (1991) International Symposium on Oxygenases and Oxygen Activation (Yamamoto, S., Nozaki, M., and Ishimura, Y., eds) pp. 133-136, Yamada Science Foundation, Osaka, Japan
14. Gerber, N. C., and Sligar, S. G. (1992) J. Am. Chem. Soc. 114, 8742-8743
15. Gerber, N. C., and Sligar, S. G. (1994) J. Biol. Chem. 269, 4260-4266
16. Vidakovic, M., Sligar, S. G., Li, H., and Poulos, T. L. (1998) Biochemistry 37, 9211-9219
17. Raag, R., Martinis, S. A., Sligar, S. G., and Poulos, T. L. (1991) Biochemistry 30, 11420-11429
18. Schlichting, I., Berendzen, J., Chu, K., Stock, A. M., Maves, S. A., Benson, D. E., Sweet, R. M., Ringe, D., Petsko, G. A., and Sligar, S. G. (2000) Science 287, 1615-1622
19. Nagano, S., Tosha, T., Ishimori, K., Morishima, I., and Poulos, T. L. (2004) J. Biol. Chem. 279, 42844-42849
20. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
21. Read, R. J. (2001) Acta Crystallogr. Sect. D Biol. Crystallogr. 57, 1373-1382
22. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. Sect. A 47, 110-119
23. Kimata, Y., Shimada, H., Hirose, T., and Ishimura, Y. (1995) Biochem. Biophys. Res. Commun. 208, 96-102
24. Ingraham, L. L., and Meyer, D. L. (1985) Biochemistry of Dioxygen (Friedman, E., ed) Plenum Publishing, New York
25. Harris, D., and Loew, G. (1993) J. Am. Chem. Soc. 115, 8775-8779
26. Nagano, S., Cupp-Vickery, J. R., and Poulos, T. L. (2005) J. Biol. Chem. 208, 22102-22107