Developmental changes in steroidogenic enzymes in human postnatal adrenal cortex: Immunohistochemical studies

Clinical Endocrinology

Volumn 53, Issue 6, 2000, Pages 739-747

  Suzuki, Takashi ^a   Sasano, Hironobu ^a   Takeyama, Junji ^a   Kaneko, Chika ^a   Freije, William A ^b   Carr, Bruce R ^b   Rainey, William E ^b  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME B5; CYTOCHROME P450 REDUCTASE; STEROID; STEROID 17ALPHA MONOOXYGENASE; STERYL SULFATASE;

ADOLESCENT; ADRENAL CORTEX; ADRENARCHE; ADULT; ARTICLE; CHILD; ENZYME ACTIVITY; ENZYME ANALYSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFANT; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; ZONA FASCICULATA; ZONA GLOMERULOSA;

3-HYDROXYSTEROID DEHYDROGENASES; ADOLESCENT; ADRENAL CORTEX; ADULT; AGING; CHILD; CHILD, PRESCHOOL; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CYTOCHROMES; CYTOCHROMES B5; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; INFANT; MIDDLE AGED; NADPH-FERRIHEMOPROTEIN REDUCTASE; STEROID 17-ALPHA-HYDROXYLASE; SULFOTRANSFERASES; ZONA FASCICULATA; ZONA GLOMERULOSA; ZONA RETICULARIS;

EID: 0034493776     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2000.01144.x     Document Type: Article

References (36)

1. Functional maturation of the primate fetal adrenal in vivo. II. Ontogeny of corticosteroid synthesis is dependent upon specific zonal expression of 3 betahydroxysteroid dehydrogenase/isomerase
2. Functional maturation of the primate fetal adrenal in vivo: 3. Specific zonal localization and developmental regulation of CYP21A2 (P450c21) and CYP11B1/CYP, 11B2 (P450c:11/aldosterone synthase) lead to integrated concept of zonal and temporal steroid biosynthesis
3. Decrease in the expression of the 3beta-hydroxysteroid dehydrogenase gene in human adrenal tissue during prepuberty and early puberty: Implications for the mechanism of adrenarche
4. The prepuberal and puberal growth of the adrenal (adrenarche)
5. Expression of 17450 oxidoreductase in the human adrenal gland
6. Quantitation in immunohistochemistry. A research method or a diagnostic tool in surgical pathology?
7. Adrenarche results from development of a 3beta-hydroxysteroid dehydrogenase-deficient adrenal reticularis
8. Structural characterization of normal and mutant human steroid 17 alpha-hydroxylase genes: Molecular basis of one example of combined 17 alpha-hydroxylase/17,20 lyase deficiency
9. Embryology, developmental anatomy, and selected aspects of non-neoplastic pathology
10. Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: Contributions of serine106 and P450 reductase
11. Quantification of immunohistochemistry using an image analyser: Correlation with hormone concentrations in pituitary adenomas
12. Assignment of the gene for adrenal P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase) to human chromosome 10
13. Co-induction of 17 alphahydroxylase and C-17,20-lyase activities in primary cultures of bovine adrenocortical cells in response to ACTH treatment
14. Localization of cytochrome P450 cholesterol side-chain cleavage, cytochrome P450, 17 alpha-hydroxylase/17, 20-lyase, and 3 beta-hydroxysteroid dehydrogenase isomerase steroidogenic enzymes in human and rhesus monkey fetal adrenal glands: Reappraisal of functional zonation
15. Developmental and functional biology of the primate fetal adrenal cortex
16. The regulation of 17,20 lyase activity
17. Functional activity of the adrenal cortex
18. Adrenarche
19. Dehydroepiandrosterone and dehydroepiandrosterone sulfate production in the human adrenal during development and aging
20. Control of adrenal androgen secretion
21. The adrenarche: Prolactin, gonadotropins, adrenal androgens, and cortisol
22. Unconjugated dehydroepiandrosterone plasma levels in normal subjects from birth to adolescence in human: The use of a sensitive radioimmunoassay
23. Adrenarche: Changing adrenal response to adrenocorticotropin
24. Localization of steroidogenic enzymes in adrenal cortex and its disorders
25. Immunohistochemical study of cytochrome P-45017 alpha in human adrenocortical disorders
26. Immunolocalization of 3beta-hydroxysteroid dehydrogenase in human adrenal cortex and its disorders
27. Immunohistochemical demonstration of cholesterol side-chain cleavage cytochrome P-450 in bovine and human adrenals
28. Immunolocalization of dehydroepiandrosterone sulfotransferase in normal and pathologic human adrenal gland
29. The developmental changes in plasma adrenal androgens during infancy and adrenarche are associated with changing activities of adrenal microsomal 17-hydroxylase and 17,20-desmolase
30. Studies on cytochrome P-450 (P-450 17 alpha,lyase) from guinea pig adrenal microsomes. Dual function of a single enzyme and effect of cytochrome b5
31. Evidence for dissociation between adrenarche and gonadarche: Studies in patients with idiopathic precocious puberty, gonadal dysgenesis, isolated gonadotropin deficiency, and constitutionally delayed growth and adolescence
32. Quantitation of 17450 aromatase immunoreactivity in human ovary during the menstrual cycle: Relationship between the enzyme activity and immunointensity
33. Hormonal changes in girls with precocious adrenarche: A possible role for estradiol or prolactin
34. Human NADPH-P450 oxidoreductase: Complementary DNA cloning, sequence and vaccinia virus-mediated expression and localization of the CYPOR gene to chromosome 7
35. Role of electron transport in the regulation of the lyase activity of C21 side-chain cleavage P-450 from porcine adrenal and testicular microsomes
36. Immunohistochemical study of cytochrome b5 in human adrenal gland and in adrenocortical adenomas from patients with Cushing's syndrome