Kinetic analysis of the three-step steroid aromatase reaction of human cytochrome P450 19A1

Journal of Biological Chemistry

Volumn 285, Issue 23, 2010, Pages 17734-17743

  Sohl, Christal D ^a   Guengerich, F Peter ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; CYTOCHROME P450; DISSOCIATION CONSTANT; EN-ROUTE; HETEROLOGOUS EXPRESSION; HUMAN CYTOCHROME; KINETIC ANALYSIS; KINETIC MODELS; LIGAND BINDING; OVERALL REACTIONS; PROGRESS CURVES; REDUCTION RATE; SEQUENTIAL REACTION; STEADY-STATE CONVERSIONS; TIME COURSE; TWO-STEP PROCESS;

ALDEHYDES; DISSOCIATION; ESCHERICHIA COLI; RATE CONSTANTS;

REACTION INTERMEDIATES;

ALDEHYDE; ANDROGEN; ANDROSTENEDIONE; AROMATASE; COMPLEMENTARY DNA; ESTROGEN; ESTRONE;

ARTICLE; BINDING KINETICS; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME PURIFICATION; ESCHERICHIA COLI; GENETIC MANIPULATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ULTRAVIOLET SPECTROSCOPY;

AMINO ACID SEQUENCE; ANDROSTENEDIONE; ANIMALS; AROMATASE; CYTOCHROME P-450 ENZYME SYSTEM; ESTRONE; HUMANS; IRON; KINETICS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; STEROIDS;

ESCHERICHIA COLI;

EID: 77952941507     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.123711     Document Type: Article

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