Human cytochrome b5 requires residues E48 and E49 to stimulate the 17,20-lyase activity of cytochrome P450c17

Biochemistry

Volumn 45, Issue 3, 2006, Pages 755-762

  Naffin Olivos, Jacqueline L ^a   Auchus, Richard J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; ELECTRON TRANSITIONS; HORMONES; MUTAGENESIS;

CYTOCHROMES; ELECTRON TRANSFER; HUMAN STEROID; MUTATION;

ENZYMES;

APOLIPOPROTEIN B; CYTOCHROME B5; CYTOCHROME P450C17; STEROID 17,20 LYASE; STEROID 17ALPHA MONOOXYGENASE; GLUTAMIC ACID; LYASE;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; ELECTRON TRANSPORT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STEROIDOGENESIS; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; POINT MUTATION; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CELL LINE; CYTOCHROMES B5; GLUTAMIC ACID; HUMANS; LYASES; MODELS, MOLECULAR; POINT MUTATION; STEROID 17-ALPHA-HYDROXYLASE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 31044440024     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051623y     Document Type: Article

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