Bleeding response induced by anti-thrombotic doses of a phosphoinositide 3-kinase (PI3K)-β inhibitor in mice

Thrombosis Research

Volumn 127, Issue 6, 2011, Pages 560-564

  Bird, J Eileen ^a   Smith, Patricia L ^a   Bostwick, Jeffrey S ^a   Shipkova, Petia ^a   Schumacher, William A ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Haemostasis; Platelet; Rat; TGX 221; Thrombosis

Indexed keywords

9 (1 ANILINOETHYL) 7 METHYL 2 MORPHOLINOPYRIDO[1,2 A]PYRIMIDIN 4 ONE; ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; PHOSPHATIDYLINOSITOL 3 KINASE BETA INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICOAGULATION; ARTICLE; BLEEDING TIME; BLOOD FLOW; CAROTID ARTERY THROMBOSIS; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; HEMOSTASIS; KIDNEY HEMORRHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SHEAR STRESS; TAIL; THROMBOCYTE AGGREGATION; VASCULAR PATENCY;

ANIMALS; BLEEDING TIME; BLOOD PLATELETS; CAROTID ARTERY THROMBOSIS; DISEASE MODELS, ANIMAL; FIBRINOLYTIC AGENTS; HEMORRHAGE; HUMANS; KIDNEY; MALE; MICE; MICE, INBRED C57BL; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; PYRIMIDINONES; RATS; RATS, SPRAGUE-DAWLEY; TAIL;

EID: 79957617106     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.02.007     Document Type: Article

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