Advantages of a selective β-isoform phosphoinositide 3-kinase antagonist, an anti-thrombotic agent devoid of other cardiovascular actions in the rat

European Journal of Pharmacology

Volumn 587, Issue 1-3, 2008, Pages 209-215

  Sturgeon, Sharelle A ^a   Jones, Catherine ^a   Angus, James A ^a   Wright, Christine E ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

(Rat model); Anti thrombotic drug; Arterial thrombosis; Phosphoinositide 3 kinase

Indexed keywords

2 (6 AMINO 9 PURINYLMETHYL) 5 METHYL 3 (2 METHYLPHENYL) 3H QUINAZOLIN 4 ONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 9 (1 ANILINOETHYL) 7 METHYL 2 MORPHOLINOPYRIDO[1,2 A]PYRIMIDIN 4 ONE; ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; HEPARIN; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY DILATATION; ARTERY THROMBOSIS; ARTICLE; BLEEDING TIME; BLOOD PRESSURE; CAROTID ARTERY; CAROTID ARTERY OBSTRUCTION; COMPARATIVE STUDY; CONTROLLED STUDY; HEART RATE; HYPOTENSION; MALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTICOAGULANTS; BLEEDING TIME; BLOOD PRESSURE; CARDIOVASCULAR AGENTS; ENOXAPARIN; ENZYME INHIBITORS; FIBRINOLYTIC AGENTS; HEART RATE; MALE; MESENTERIC ARTERIES; MORPHOLINES; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; PYRIMIDINONES; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; STRESS; SUBSTRATE SPECIFICITY; VASCULAR RESISTANCE;

EID: 44149087073     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.03.017     Document Type: Article

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