Phosphoinositide 3-kinase induced activation and cytoskeletal translocation of protein kinase CK2 in protease activated receptor 1-stimulated platelets

Thrombosis Research

Volumn 126, Issue 6, 2010, Pages 511-516

  Nakanishi, Kyoichi ^a,b   Toyoda, Hidemi ^b   Tanaka, Sigeki ^a,c   Yamamoto, Hatsumi ^a,c   Komada, Yoshihiro ^b   Gabazza, Esteban C ^c   Hayashi, Tatsuya ^d   Suzuki, Koji ^c   Ido, Masaru ^a,c  

^a National Hospital Organization Mie Chuo Medical Center   (Japan)

^b MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c MIE UNIVERSITY   (Japan)

^d MIE PREFECTURAL COLLEGE OF NURSING   (Japan)

Author keywords

Casein Kinase 2; CK2; PAR1; PI 3 kinase; Protein kinase CK2; Thrombin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASEIN KINASE II; FIBRINOGEN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE INHIBITOR; PROTEINASE ACTIVATED RECEPTOR 1; WORTMANNIN;

ARTICLE; CYTOSKELETON; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

BLOOD PLATELETS; CASEIN KINASE II; CYTOSKELETON; ENZYME ACTIVATION; HUMANS; IMMUNOPRECIPITATION; PHOSPHATIDYLINOSITOL 3-KINASES; PLATELET AGGREGATION; PLATELET COUNT; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN KINASE INHIBITORS; RECEPTOR, PAR-1;

EID: 78649749545     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2010.09.016     Document Type: Article

References (28)

1. P.T. Tuazon, and J.A. Traugh Casein kinase I and II-multipotential serine protein kinases: structure, function, and regulation Adv Second Messenger Phosphoprotein Res 23 1991 123 164
2. B. Guerra, and O.G. Issinger Protein kinase CK2 and its role in cellular proliferation, development and pathology Electrophoresis 20 1999 391 408
3. C.H. Hoyt, C.J. Oh, J.B. Beekman, D.W. Litchfield, and K.M. Lerea Identifying and characterizing casein kinase II in human platelets Blood 83 1994 3517 3523
4. M.L. Kahn, M. Nakanishi-Matsui, M.J. Shapiro, H. Ishihara, and S.R. Coughlin Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin J Clin Invest 103 1999 879 887
5. P. Lova, S. Paganini, E. Hirsch, L. Barberis, M. Wymann, and F. Sinigaglia A selective role for phosphatidylinositol 3, 4, 5-trisphosphate in the Gi-dependent activation of platelet Rap1B J Biol Chem 278 2003 131 138
6. P. Grondin, M. Plantavid, C. Sultan, M. Breton, G. Mauco, and H. Chap Interaction of pp 60c-src, phospholipase C, inositol-lipid, and diacyglycerol kinases with the cytoskeletons of thrombin-stimulated platelets J Biol Chem 266 1991 15705 15709
7. C. Guinebault, B. Payrastre, C. Racaud-Sultan, H. Mazarguil, M. Breton, and G. Mauco Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 a with actin filaments and focal adhesion kinase J Cell Biol 129 1995 831 842
8. J.M. Cosemans, I.C. Munnix, R. Wetzker, R. Heller, S.P. Jackson, and J.W. Heemskerk Continuous signaling via PI3K isoforms beta and gamma is required for platelet ADP receptor function in dynamic thrombus stabilization Blood 108 2006 3045 3052
9. S.J. Shattil, J.A. Hoxie, M. Cunningham, and L.F. Brass Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation J Biol Chem 260 1985 11107 11114
10. F. Meggio, D. Shugar, and L.A. Pinna Ribofuranosyl-benzimidazole derivatives as inhibitors of casein kinase-2 and casein kinase-1 Eur J Biochem 187 1990 89 94
11. M.A. Pagano, F. Meggio, M. Ruzzene, M. Andrzejewska, Z. Kazimierczuk, and L.A. Pinna 2-Dimethylamino-4, 5, 6, 7-tetrabromo-1 H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2 Biochem Biophys Res Commun 321 2004 1040 1044
12. M.A. Pagano, J. Bain, Z. Kazimierczuk, S. Sarno, M. Ruzzene, and G. Di Maira The selectivity of inhibitors of protein kinase CK2: an update Biochem J 415 2008 353 365
13. S.J. Shattil, M. Cunningham, and J.A. Hoxie Detection of activated platelets in whole blood using activation-dependent monoclonal antibodies and flow cytometry Blood 70 1987 307 315
14. R. Zandomeni, and R. Weinmann Inhibitory effect of 5, 6-dichloro-1-b-D-ribofuranosylbenzimidazole on a protein kinase J Biol Chem 259 1984 14804 14811
15. R. Zandomeni, M.C. Zandomeni, D. Shugar, and R. Weinmann Casein kinase type II is involved in the inhibition by 5, 6-dichloro-1-b-D- ribofuranosylbenzimidazole of specific RNA polymerase II transcription J Biol Chem 261 1986 3414 3419
16. H. Ogawa, M. Ido, H. Takeya, and K. Suzuki The thrombin receptor transmits signals through a 33-kDa protein kinase in human platelets Biochem Biophys Res Commun 203 1994 907 913
17. 2+-dependent activation of the 33-kDa protein kinase transmits thrombin receptor signals in human platelets Thromb Haemost 76 1996 439 443
18. M. Ido, T. Hayashi, E.C. Gabazza, and K. Suzuki Identification of a novel 33-kDa Ser/Thr kinase that phosphorylates the cytoplasmic tail of protease-activated receptor 1 (thrombin receptor) in human platelets Thromb Haemost 83 2000 617 621
19. M. Ui, T. Okada, K. Hazeki, and O. Hazeki Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase Trends Biochem Sci 20 1995 303 307
20. C.J. Vlahos, W.F. Matter, K.Y. Hui, and R.F. Brown A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4 H-1-benzopyran-4-one (LY294002) J Biol Chem 269 1994 5241 5248
21. V. Fuster, L. Badimon, J.J. Badimon, and J.H. Chesebro The pathogenesis of coronary artery disease and the acute coronary syndromes (2) N Engl J Med 326 1992 310 318
22. S.M. Boekholdt, R.J. Peters, M.P. de Maat, A.H. Zwinderman, E.E. van Der Wall, and P.H. Reitsma Interaction between a genetic variant of the platelet fibrinogen receptor and fibrinogen levels in determining the risk of cardiovascular events Am Heart J 147 2004 181 186
23. 2+ mobilization and synergistic P2Y12 receptor activation J Biol Chem 281 2006 26665 26674
24. K. Nakanishi, Y. Komada, T. Hayashi, K. Suzuki, and M. Ido Protease activated receptor 1 activation of platelet is associated with an increase in protein kinase CK2 activity J Thromb Haemost 6 2008 1046 1048
25. J.S. Bennett Structure and function of the platelet integrin aIIbb3 J Clin Invest 115 2005 3363 3369
26. B. Voss, J.N. McLaughlin, M. Holinstat, R. Zent, and H.E. Hamm PAR1, but not PAR4, activates human platelets through a Gi/o/phosphoinositide-3 kinase signaling axis Mol Pharmacol 71 2007 1399 1406
27. G. Kauffenstein, W. Bergmeier, A. Eckly, P. Ohlmann, C. Leon, and J.P. Cazenave The P2Y12 receptor induces platelet aggregation through weak activation of the aIIbb3 integrin-a phosphoinositide 3-kinase-dependent mechanism FEBS Lett 505 2001 281 290
28. T.J. Kovacsovics, C. Bachelot, A. Toker, C.J. Vlahos, B. Duckworth, and L.C. Cantley Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation J Biol Chem 270 1995 11358 11366