Comparative analysis of germline and somatic microlesion mutational spectra in 17 human tumor suppressor genes

Human Mutation

Volumn 32, Issue 6, 2011, Pages 620-632

  Ivanov, Dobril ^a,b   Hamby, Stephen E ^c   Stenson, Peter D ^a   Phillips, Andrew D ^a   Kehrer Sawatzki, Hildegard ^d   Cooper, David N ^a   Chuzhanova, Nadia ^c  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^c NOTTINGHAM TRENT UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF ULM   (Germany)

Author keywords

Driver mutations; Germline and somatic mutational spectra; Mutation hotspot; Non B DNA; Recurrent mutation; Tumor suppressor genes

Indexed keywords

OLIGONUCLEOTIDE;

APC GENE; ARTICLE; ATM GENE; BRCA2 GENE; CDH1 GENE; CDKN2A GENE; COMPARATIVE GENE MAPPING; GENE DELETION; GENE INSERTION; GENE MUTATION; GERMLINE MUTATION; HUMAN; MISSENSE MUTATION; NF1 GENE; NF2 GENE; ONCOGENE; PRIORITY JOURNAL; PTCH1 GENE; PTEN GENE; RB1 GENE; SOMATIC MUTATION; STK11 GENE; TP53 GENE; TSC1 GENE; TSC2 GENE; TUMOR SUPPRESSOR GENE; VHL GENE; WT1 GENE;

CELL TRANSFORMATION, NEOPLASTIC; COMPUTATIONAL BIOLOGY; DNA MUTATIONAL ANALYSIS; GERM-LINE MUTATION; HUMANS; INDEL MUTATION; MUTATION; NEOPLASMS; TUMOR SUPPRESSOR PROTEINS;

EID: 79957603893     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21483     Document Type: Article

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