Analysis of NF1 somatic mutations in cutaneous neurofibromas from patients with high tumor burden

Neurogenetics

Volumn 11, Issue 4, 2010, Pages 391-400

  Thomas, Laura ^a   Kluwe, Lan ^b   Chuzhanova, Nadia ^c   Mautner, Victor ^b   Upadhyaya, Meena ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c UNIVERSITY OF CENTRAL LANCASHIRE   (United Kingdom)

Author keywords

Cutaneous neurofibromas; Germline mutations; NF1; Somatic mutations; TP53

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; NEUROFIBROMIN; PROTEIN P53;

ADULT; AGED; ARTICLE; BENIGN TUMOR; CASE REPORT; DNA FLANKING REGION; FEMALE; GENE LOCUS; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MALE; MICROSATELLITE INSTABILITY; NEUROFIBROMA; PRIORITY JOURNAL; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE; TUMOR VOLUME;

ADULT; COMPUTATIONAL BIOLOGY; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA MUTATIONAL ANALYSIS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, NEUROFIBROMATOSIS 1; GENES, P53; GERM-LINE MUTATION; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; MUTATION; NEUROFIBROMA; RETINOBLASTOMA PROTEIN; SKIN NEOPLASMS;

EID: 78650037225     PISSN: 13646745     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10048-010-0240-y     Document Type: Article

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