메뉴 건너뛰기




Volumn 56, Issue 9, 1996, Pages 2130-2136

Deletions and insertions in the p53 tumor suppressor gene in human cancers: Confirmation of the DNA polymerase slippage/misalignment model

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; PROTEIN P53;

EID: 0029996282     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (109)

References (60)
  • 1
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt, M. S , Bennett, W. P., Hollstein, M., and Harris, C. C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis Cancer Res., 54. 4855-4878, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 5
    • 0025109103 scopus 로고
    • Misalignment-mediated DNA synthesis errors
    • Kunkel, T. A. Misalignment-mediated DNA synthesis errors. Biochemistry, 29. 8003-8011, 1990.
    • (1990) Biochemistry , vol.29 , pp. 8003-8011
    • Kunkel, T.A.1
  • 6
    • 0025630591 scopus 로고
    • Frameshift mutation: Determinants of specificity
    • Ripley, L. S. Frameshift mutation: determinants of specificity. Annu. Rev Genet., 24: 189-213, 1990
    • (1990) Annu. Rev Genet. , vol.24 , pp. 189-213
    • Ripley, L.S.1
  • 7
    • 0013997442 scopus 로고
    • Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday
    • Streisinger, G , Okada, Y., Emrich, J , Newton, J., Tsugita, A , Terzaghi, E., and Inouye, M. Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday. Cold Spring Harbor Symp Quant Biol., 31: 77-84, 1966.
    • (1966) Cold Spring Harbor Symp Quant Biol. , vol.31 , pp. 77-84
    • Streisinger, G.1    Okada, Y.2    Emrich, J.3    Newton, J.4    Tsugita, A.5    Terzaghi, E.6    Inouye, M.7
  • 8
    • 0025309892 scopus 로고
    • Frameshift errors initiated by nucleotide misincorporation
    • Benebek, K., and Kunkel, T. A. Frameshift errors initiated by nucleotide misincorporation. Proc. Natl. Acad. Sci. USA, 87. 4946-4950, 1995
    • (1995) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4946-4950
    • Benebek, K.1    Kunkel, T.A.2
  • 9
    • 0027196408 scopus 로고
    • On the mechanism of frameshift (deletion) mutagenesis in vitro
    • Shibutani, S , and Grollman, A. P. On the mechanism of frameshift (deletion) mutagenesis in vitro J Biol. Chem., 268: 11703-11710, 1993.
    • (1993) J Biol. Chem. , vol.268 , pp. 11703-11710
    • Shibutani, S.1    Grollman, A.P.2
  • 10
    • 0027532034 scopus 로고
    • Short direct repeats flanking deletions, and duplicating insertions in p53 gene in human cancers
    • Jego, N , Thomas, G., and Hamelin, R. Short direct repeats flanking deletions, and duplicating insertions in p53 gene in human cancers Oncogene, 8: 209-213, 1993
    • (1993) Oncogene , vol.8 , pp. 209-213
    • Jego, N.1    Thomas, G.2    Hamelin, R.3
  • 11
    • 0025762012 scopus 로고
    • Gene deletions causing human genetic disease: Mechanisms of mutagenesis and the role of the local DNA sequence environment
    • Krawczak, M., and Cooper, D N. Gene deletions causing human genetic disease: mechanisms of mutagenesis and the role of the local DNA sequence environment. Hum. Genet., 86: 425-441, 1991.
    • (1991) Hum. Genet. , vol.86 , pp. 425-441
    • Krawczak, M.1    Cooper, D.N.2
  • 12
    • 0019996193 scopus 로고
    • On the formation of spontaneous deletions, the importance of short sequence homologies in the generation of large deletions
    • Albertini, A. M., Hofer, M., Calos, M P, and Miller, J H. On the formation of spontaneous deletions, the importance of short sequence homologies in the generation of large deletions. Cell, 29: 319-328, 1982
    • (1982) Cell , vol.29 , pp. 319-328
    • Albertini, A.M.1    Hofer, M.2    Calos, M.P.3    Miller, J.H.4
  • 13
    • 0027502171 scopus 로고
    • Mechanisms involved in rejoining DNA double-strand breaks induced by ionizing radiation and restriction enzymes
    • Lutze, L. H., Cleaver, J. E , Morgan, W F., and Winegar, R. A. Mechanisms involved in rejoining DNA double-strand breaks induced by ionizing radiation and restriction enzymes. Mutat. Res , 299: 225-232, 1993
    • (1993) Mutat. Res , vol.299 , pp. 225-232
    • Lutze, L.H.1    Cleaver, J.E.2    Morgan, W.F.3    Winegar, R.A.4
  • 14
    • 0026786303 scopus 로고
    • Radon-induced deletions in human cells: Role of nonhomologous strand rejoining
    • Lutze, L H., Winegar, R. A., Jostes, R , Cross, F. T., and Cleaver, J E. Radon-induced deletions in human cells: role of nonhomologous strand rejoining. Cancer Res., 52: 5126-5129, 1992
    • (1992) Cancer Res. , vol.52 , pp. 5126-5129
    • Lutze, L.H.1    Winegar, R.A.2    Jostes, R.3    Cross, F.T.4    Cleaver, J.E.5
  • 15
    • 0022730368 scopus 로고
    • Spontaneous deletion formation at the aprt locus of hamster cells: The presence of short sequence homologies and dyad symmetries at deletion termini
    • Nalbantoglu, J , Hartley, D., Phear, G., Tear, G , and Meuth, M. Spontaneous deletion formation at the aprt locus of hamster cells: the presence of short sequence homologies and dyad symmetries at deletion termini EMBO J., 5: 1199-1204, 1986.
    • (1986) EMBO J. , vol.5 , pp. 1199-1204
    • Nalbantoglu, J.1    Hartley, D.2    Phear, G.3    Tear, G.4    Meuth, M.5
  • 16
    • 0021324522 scopus 로고
    • Structural intermediates of deletion mutagenesis: A role for palindrome DNA
    • Glickman, B. W., and Ripley, L. S. Structural intermediates of deletion mutagenesis: a role for palindrome DNA. Proc. Natl. Acad Sci. USA, 81. 512-516, 1984
    • (1984) Proc. Natl. Acad Sci. USA , vol.81 , pp. 512-516
    • Glickman, B.W.1    Ripley, L.S.2
  • 17
    • 0028349973 scopus 로고
    • Complex frameshift mutations mediated by plasmid pKM101: Mutational mechanisms deduced from 4-aminobiphenyl-induced mutation spectra in Salmonella
    • Levine, J. G., Schaaper, R. M., and DeMarini, D. M. Complex frameshift mutations mediated by plasmid pKM101: mutational mechanisms deduced from 4-aminobiphenyl-induced mutation spectra in Salmonella. Genetics, 136: 731-746, 1994.
    • (1994) Genetics , vol.136 , pp. 731-746
    • Levine, J.G.1    Schaaper, R.M.2    DeMarini, D.M.3
  • 18
    • 0026536986 scopus 로고
    • Carcinogen-induced frameshift mutagenesis in repetitive sequences
    • Lambert, I. B., Napolitano, R. L., and Fuchs, R P. Carcinogen-induced frameshift mutagenesis in repetitive sequences. Proc. Natl. Acad. Sci. USA, 89. 1310-1314, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1310-1314
    • Lambert, I.B.1    Napolitano, R.L.2    Fuchs, R.P.3
  • 19
    • 0025887465 scopus 로고
    • Strong sequence-dependent polymorphism in adduct-induced DNA structure: Analysis of single N-2-acetylaminofluorene residues bound within the NarI mutation hot spot
    • Belguise-Valladier, P., and Fuchs, R. P. Strong sequence-dependent polymorphism in adduct-induced DNA structure: analysis of single N-2-acetylaminofluorene residues bound within the NarI mutation hot spot. Biochemistry, 30: 10091-10100, 1991.
    • (1991) Biochemistry , vol.30 , pp. 10091-10100
    • Belguise-Valladier, P.1    Fuchs, R.P.2
  • 20
    • 0028351180 scopus 로고
    • Proximal and distal effects of sequence context on ultraviolet mutational hotspots in a shuttle vector replicated in xeroderma cells
    • Parris, C N., Levy, D D., Jessee, J., and Seidman, M. M. Proximal and distal effects of sequence context on ultraviolet mutational hotspots in a shuttle vector replicated in xeroderma cells. J. Mol. Biol., 236: 491-502, 1994.
    • (1994) J. Mol. Biol. , vol.236 , pp. 491-502
    • Parris, C.N.1    Levy, D.D.2    Jessee, J.3    Seidman, M.M.4
  • 21
    • 0028308492 scopus 로고
    • p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions
    • Redston, M. S., Caldas, C., Seymour, A B., Hruban, R. H., da Costa, L., Yeo, C. J., and Kern, S. E. p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res., 54: 3025-3033, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3025-3033
    • Redston, M.S.1    Caldas, C.2    Seymour, A.B.3    Hruban, R.H.4    Da Costa, L.5    Yeo, C.J.6    Kern, S.E.7
  • 22
    • 0025052917 scopus 로고
    • Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: The role of DNA base damage
    • Breimer, L. H. Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: the role of DNA base damage. Mol. Carcinog., 3: 188-197, 1990
    • (1990) Mol. Carcinog. , vol.3 , pp. 188-197
    • Breimer, L.H.1
  • 23
    • 0027939654 scopus 로고
    • Detection of exocyclic l 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans
    • Nath, R G., and Chung, F L. Detection of exocyclic l 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans Proc. Natl. Acad. Sci. USA, 91. 7491-7495, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7491-7495
    • Nath, R.G.1    Chung, F.L.2
  • 24
    • 0027941187 scopus 로고
    • Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver
    • Washington DC
    • Chaudhary, A. K , Nokubo, M , Reddy, G. R., Yeola, S. N., Morrow, J. D., Blair, I. A , and Marnett, L. J. Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver. Science (Washington DC), 265. 1580-1582, 1994
    • (1994) Science , vol.265 , pp. 1580-1582
    • Chaudhary, A.K.1    Nokubo, M.2    Reddy, G.R.3    Yeola, S.N.4    Morrow, J.D.5    Blair, I.A.6    Marnett, L.J.7
  • 25
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • Lindahl, T. Instability and decay of the primary structure of DNA Nature (Lond.), 362: 709-715, 1993.
    • (1993) Nature (Lond.) , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 26
    • 0027930591 scopus 로고
    • Mutation spectra of Glu-P-1 in Salmonella: Induction of hotspot frameshifts and site-specific base substitutions
    • Levine, J. G., Knasmuller, S., Shelton, M. L., and DeMarini, D. M. Mutation spectra of Glu-P-1 in Salmonella: induction of hotspot frameshifts and site-specific base substitutions. Environ. Mol. Mutagen , 24: 11-22, 1994
    • (1994) Environ. Mol. Mutagen , vol.24 , pp. 11-22
    • Levine, J.G.1    Knasmuller, S.2    Shelton, M.L.3    DeMarini, D.M.4
  • 27
    • 0024331441 scopus 로고
    • Mutagenesis by single site-specific arylamine-DNA adducts. Induction of mutations at multiple sites
    • Gupta, P. K., Johnson, D. L., Reid, T M., Lee, M. S , Romano, L. J , and King, C. M. Mutagenesis by single site-specific arylamine-DNA adducts. Induction of mutations at multiple sites. J. Biol. Chem., 264. 20120-20130, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 20120-20130
    • Gupta, P.K.1    Johnson, D.L.2    Reid, T.M.3    Lee, M.S.4    Romano, L.J.5    King, C.M.6
  • 28
    • 0023973620 scopus 로고
    • Targeted mutations induced by a single acetylaminofluorene DNA adduct in mammalian cells and bacteria
    • Moriya, M., Takeshita, M., Johnson, F., Peden, K., Will, S , and Grollman, A. P. Targeted mutations induced by a single acetylaminofluorene DNA adduct in mammalian cells and bacteria. Proc Natl Acad. Sci USA, 85: 1586-1589, 1988
    • (1988) Proc Natl Acad. Sci USA , vol.85 , pp. 1586-1589
    • Moriya, M.1    Takeshita, M.2    Johnson, F.3    Peden, K.4    Will, S.5    Grollman, A.P.6
  • 29
    • 0026636947 scopus 로고
    • In vitro evidence that UV-induced frameshift and substitution mutations at T tracts are the result of misalignment-mediated replication past a specific thymine dimer
    • Wang, C. I., and Taylor, J. S. In vitro evidence that UV-induced frameshift and substitution mutations at T tracts are the result of misalignment-mediated replication past a specific thymine dimer. Biochemistry, 31: 3671-3681, 1992.
    • (1992) Biochemistry , vol.31 , pp. 3671-3681
    • Wang, C.I.1    Taylor, J.S.2
  • 30
    • 0039547559 scopus 로고
    • Single adduct mutagenesis: Strong effect of the position of a single acetylaminofluorene adduct within a mutation hot spot
    • Burnouf, D., Koehl, P., and Fuchs, R. P. Single adduct mutagenesis: strong effect of the position of a single acetylaminofluorene adduct within a mutation hot spot. Proc. Natl. Acad. Sci. USA, 86: 4147-4151, 1989.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 4147-4151
    • Burnouf, D.1    Koehl, P.2    Fuchs, R.P.3
  • 31
    • 0028725669 scopus 로고
    • DNA Adducts, identification and Biological Significance. Mutagenic specificity of chemical carcinogens as determined by studies of single DNA adducts
    • Grollman, A. P., and Shibutani, S DNA Adducts, identification and Biological Significance. Mutagenic specificity of chemical carcinogens as determined by studies of single DNA adducts IARC Sci Publ., 125: 385-397, 1994.
    • (1994) IARC Sci Publ. , vol.125 , pp. 385-397
    • Grollman, A.P.1    Shibutani, S.2
  • 32
    • 0025163907 scopus 로고
    • Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase
    • Mendelman, L. V , Petruska, J., and Goodman, M. F. Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase. J. Biol. Chem., 265: 2338-2346, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 2338-2346
    • Mendelman, L.V.1    Petruska, J.2    Goodman, M.F.3
  • 33
    • 0025831694 scopus 로고
    • Site-specific mutagenesis retrospective and prospective
    • Lond
    • Singer, B., and Essigmann, J. M. Site-specific mutagenesis retrospective and prospective. Carcinogenesis (Lond), 12: 949-955, 1991
    • (1991) Carcinogenesis , vol.12 , pp. 949-955
    • Singer, B.1    Essigmann, J.M.2
  • 34
    • 0025997527 scopus 로고
    • Toxicity, mutagenicity, and mutational spectra of N-ethyl-N-nitrosourea in human cell lines with different DNA repair phenotypes
    • Bronstein, S. M., Cochrane, J. E , Craft, T R., Swenberg, J. A., and Skopek, T. R. Toxicity, mutagenicity, and mutational spectra of N-ethyl-N-nitrosourea in human cell lines with different DNA repair phenotypes. Cancer Res , 51: 5188-5197, 1991.
    • (1991) Cancer Res , vol.51 , pp. 5188-5197
    • Bronstein, S.M.1    Cochrane, J.E.2    Craft, T.R.3    Swenberg, J.A.4    Skopek, T.R.5
  • 35
    • 0028981276 scopus 로고
    • The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions
    • Alani, E., Chi, N. W., and Kolodner, R The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions Genes & Dev., 9: 234-247, 1995.
    • (1995) Genes & Dev. , vol.9 , pp. 234-247
    • Alani, E.1    Chi, N.W.2    Kolodner, R.3
  • 36
    • 0028331722 scopus 로고
    • Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae
    • Alani, E., Reenan, R. A., and Kolodner, R. D. Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics, 137: 19-39, 1994
    • (1994) Genetics , vol.137 , pp. 19-39
    • Alani, E.1    Reenan, R.A.2    Kolodner, R.D.3
  • 37
    • 0027742295 scopus 로고
    • The human imitator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
    • Fishel, R , Lescoe, M. K., Rao, M. R., Copeland, N. G., Jenkins, N. A , Garber, J , Kane, M., and Kolodner, R The human imitator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell, 75: 1027-1038, 1993.
    • (1993) Cell , vol.75 , pp. 1027-1038
    • Fishel, R.1    Lescoe, M.K.2    Rao, M.R.3    Copeland, N.G.4    Jenkins, N.A.5    Garber, J.6    Kane, M.7    Kolodner, R.8
  • 41
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • Washington DC
    • Thibodeau, S. N., Bren, G., and Schaid, D Microsatellite instability in cancer of the proximal colon. Science (Washington DC), 260: 816-819, 1993.
    • (1993) Science , vol.260 , pp. 816-819
    • Thibodeau, S.N.1    Bren, G.2    Schaid, D.3
  • 43
    • 0027323079 scopus 로고
    • Mismatch recognition in chromosomal interactions and speciation
    • Berl.
    • Radman, M., and Wagner, R. Mismatch recognition in chromosomal interactions and speciation. Chromosoma (Berl.), 102: 369-373, 1993.
    • (1993) Chromosoma , vol.102 , pp. 369-373
    • Radman, M.1    Wagner, R.2
  • 44
    • 0029145505 scopus 로고
    • MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair
    • Hollingsworth, N. M , Ponte, L., and Halsey, C. MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair. Genes & Dev , 9: 1728-1739, 1995.
    • (1995) Genes & Dev , vol.9 , pp. 1728-1739
    • Hollingsworth, N.M.1    Ponte, L.2    Halsey, C.3
  • 46
    • 0029101616 scopus 로고
    • Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
    • de Wind, N., Dekker, M., Berns, A., Radman, M., and te Riele, H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell, 82: 321-330, 1995.
    • (1995) Cell , vol.82 , pp. 321-330
    • De Wind, N.1    Dekker, M.2    Berns, A.3    Radman, M.4    Te Riele, H.5
  • 47
    • 0025290268 scopus 로고
    • Underwinding of DNA associated with duplex-duplex pairing by RecA protein
    • Conley, E. C., and West, S. C. Underwinding of DNA associated with duplex-duplex pairing by RecA protein. J. Biol. Chem., 265: 10156-10163, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10156-10163
    • Conley, E.C.1    West, S.C.2
  • 48
    • 0026740399 scopus 로고
    • The synapsis event in the homologous pairing of DNAs: RecA recognizes and pairs less than one helical repeat of DNA
    • Hsieh, P , Camerini-Otero, C S., and Camerini-Otero, R. D. The synapsis event in the homologous pairing of DNAs: RecA recognizes and pairs less than one helical repeat of DNA. Proc. Natl. Acad. Sci. USA. 89: 6492-6496, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA. , vol.89 , pp. 6492-6496
    • Hsieh, P.1    Camerini-Otero, C.S.2    Camerini-Otero, R.D.3
  • 49
    • 0018801605 scopus 로고
    • Genetic and physical mapping in the early region of bacteriophage T7 DNA
    • Studier, F. W., Rosenberg, A. H , Simon, M. N., and Dunn, J. J. Genetic and physical mapping in the early region of bacteriophage T7 DNA. J. Mol Biol., 135: 917-937, 1979.
    • (1979) J. Mol Biol. , vol.135 , pp. 917-937
    • Studier, F.W.1    Rosenberg, A.H.2    Simon, M.N.3    Dunn, J.J.4
  • 50
    • 0027146559 scopus 로고
    • Mutations of the APC gene
    • Nagase, H., and Nakamura, Y. Mutations of the APC gene Hum. Mutat., 2 425-434, 1993.
    • (1993) Hum. Mutat. , vol.2 , pp. 425-434
    • Nagase, H.1    Nakamura, Y.2
  • 51
    • 0028566272 scopus 로고
    • MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma
    • Lond
    • Yeudall, W. A., Crawford, R. Y., Ensley, J F. and Robbins, K C. MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma. Carcinogenesis (Lond), 15: 2683-2686, 1994
    • (1994) Carcinogenesis , vol.15 , pp. 2683-2686
    • Yeudall, W.A.1    Crawford, R.Y.2    Ensley, J.F.3    Robbins, K.C.4
  • 55
    • 0028303752 scopus 로고
    • Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
    • Lin, J , Chen, J , Elenbaas, B., and Levine, A, J. Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein Genes & Dev., 8: 1235-1246, 1994
    • (1994) Genes & Dev. , vol.8 , pp. 1235-1246
    • Lin, J.1    Chen, J.2    Elenbaas, B.3    Levine, A.J.4
  • 56
    • 0028519273 scopus 로고
    • Allosteric activation of latent p53 tetramers
    • Hupp, T. R., and Lane, D. P. Allosteric activation of latent p53 tetramers. Curr. Biol., 4: 865-875, 1995
    • (1995) Curr. Biol. , vol.4 , pp. 865-875
    • Hupp, T.R.1    Lane, D.P.2
  • 57
    • 0029078067 scopus 로고
    • The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity
    • Bayle, J H , Elenbaas, B., and Levine, A. J The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity. Proc. Natl. Acad. Sci. USA, 92: 5729-5733, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5729-5733
    • Bayle, J.H.1    Elenbaas, B.2    Levine, A.J.3
  • 58
    • 0026018256 scopus 로고
    • DNA binding domain is contained in the C-terminus of wild type p53 protein
    • Foord, O. S., Bhattacharya, P., Reich, Z. and Rotter, V. A DNA binding domain is contained in the C-terminus of wild type p53 protein. Nucleic Acids Res , 19: 5191-5198, 1991.
    • (1991) Nucleic Acids Res , vol.19 , pp. 5191-5198
    • Foord, O.S.1    Bhattacharya, P.2    Reich, Z.3    Rotter, V.A.4
  • 59
    • 0029087477 scopus 로고
    • Augmented DNA-binding activity of p53 protein encoded by a carboxyl-terminal alternatively spliced mRNA is blocked by p53 protein encoded by the regularly spliced form
    • Wolkowicz, R., Peled, A., Elkind, N. B., and Rotter, V. Augmented DNA-binding activity of p53 protein encoded by a carboxyl-terminal alternatively spliced mRNA is blocked by p53 protein encoded by the regularly spliced form. Proc. Natl. Acad. Sci USA, 92. 6842-6846, 1995.
    • (1995) Proc. Natl. Acad. Sci USA , vol.92 , pp. 6842-6846
    • Wolkowicz, R.1    Peled, A.2    Elkind, N.B.3    Rotter, V.4
  • 60
    • 0029055808 scopus 로고
    • Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus
    • Jayaraman, J., and Prives, C Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus. Cell, 81: 1021-1029, 1995.
    • (1995) Cell , vol.81 , pp. 1021-1029
    • Jayaraman, J.1    Prives, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.