Atorvastatin as a potential anti-malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum.

Malaria journal

Volumn 9, Issue , 2010, Pages 139-

  Parquet, Véronique ^a   Henry, Maud ^b   Wurtz, Nathalie ^b   Dormoi, Jerome ^b   Briolant, Sébastien ^b   Gil, Marine ^b   Baret, Eric ^b   Amalvict, Rémy ^b   Rogier, Christophe ^b   Pradines, Bruno ^b  

^a SERVICE DE SANTÉ DES ARMÉES   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTIMALARIAL AGENT; ATORVASTATIN; CARRIER PROTEIN; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MDR GENE PROTEIN, PLASMODIUM; MDR1 PROTEIN, PLASMODIUM FALCIPARUM; MDR2 PROTEIN, PLASMODIUM FALCIPARUM; MULTIDRUG RESISTANCE PROTEIN; PFCRT PROTEIN, PLASMODIUM FALCIPARUM; PROTOZOAL PROTEIN; PYRROLE DERIVATIVE; QUININE;

ARTICLE; DRUG EFFECT; DRUG POTENTIATION; DRUG RESISTANCE; DRUG SENSITIVITY; GENE DOSAGE; GENETIC VARIABILITY; GENETICS; GENOTYPE; IC 50; ISOLATION AND PURIFICATION; MALARIA FALCIPARUM; MUTATION; PLASMODIUM FALCIPARUM;

ANTIMALARIALS; ATP-BINDING CASSETTE TRANSPORTERS; DRUG RESISTANCE; DRUG SYNERGISM; GENE DOSAGE; GENETIC VARIATION; GENOTYPE; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INHIBITORY CONCENTRATION 50; MALARIA, FALCIPARUM; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; PYRROLES; QUININE;

EID: 77952515561     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-9-139     Document Type: Article

References (0)