Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth

Blood

Volumn 99, Issue 12, 2002, Pages 4443-4448

  Peyton, Kelly J ^a   Reyna, Sylvia V ^a   Chapman, Gary B ^a   Ensenat, Diana ^a   Liu, Xiao Ming ^a   Wang, Hong ^a   Schafer, Andrew I ^a   Durante, William ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; CARBON MONOXIDE; CYCLIN A; CYCLIN D1; CYCLIN E; DNA; HEME OXYGENASE 1; HEMOGLOBIN; MESSENGER RNA; PROTOPORPHYRIN TIN; PROTOPORPHYRIN ZINC;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CATABOLISM; CELL GROWTH; CONCENTRATION RESPONSE; DNA SYNTHESIS; ENZYME ANALYSIS; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; VASCULAR SMOOTH MUSCLE;

EID: 0037097844     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.12.4443     Document Type: Article

References (33)

1. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
2. Characterization of two constitutive forms of rat liver microsomal heme oxygenase: Only one molecular species of the enzyme is inducible
3. Heme oxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications
4. Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3
5. Nitric oxide induces heme oxygenase expression and carbon monoxide production in vascular smooth muscle cells
6. Induction of heme oxygenase-1 expression in vascular smooth muscle cells: A link to endotoxin shock
7. Hemodynamic forces induce the expression of heme oxygenase in cultured vascular smooth muscle cells
8. Purification and properties of bovine spleen heme oxygenase: Amino acid composition and sites of action of inhibitors of heme oxygenase
9. Iron regulates nitric oxide synthase activity by controlling nuclear transcription
10. Platelet-derived growth factor stimulates heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells
11. Carbon monoxide-induced vasorelaxation and the underlying mechanisms
12. Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats
13. A heme oxygenase product, presumably carbon monoxide, mediates a vasodepressor function in rats
14. Heme oxygenase-1 derived carbon monoxide contributes to the suppression of acute hypertensive responses in vivo
15. NO-mediated activation of heme oxygenase: Endogenous cytoprotection against oxidative stress to endothelium
16. Dynamics of haem oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress
17. Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency
18. Angiotensin II-induced hypertension increases heme oxygenase-1 expression in rat aorta
19. Increased expression of heme oxygenase-1 in human retinal pigment epithelial cells by transforming growth factor-β
20. Plasmin potentiates the induction of nitric oxide synthase by interleukin-1β in vascular smooth muscle
21. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
22. Determination of heme oxygenase activity in murine macrophages for studying oxidative stress
23. Carbon monoxide has antiinflammatory effects involving the mitogen-activated protein kinase pathway
24. Carbon monoxide generated by heme oxygenase 1 suppresses endothelial apoptosis
25. Cell cycle progression: New therapeutic target for vascular proliferative disease
26. Heme oxygenase-1 protects against vascular constriction and proliferation
27. The retineblastoma protein and cell cycle control
28. Endothelial cell expression of vasoconstrictors and growth factors is regulated by smooth muscle cell-derived carbon monoxide
29. Inhibition of platelet aggregation by carbon monoxide is mediated by the activation of soluble guanylate cyclase
30. Protective roles of endogenous carbon monoxide in neointimal development elicited by arterial injury
31. Balloon injury does not induce heme oxygenase-1 expression, but administration of hemin inhibits neointimal formation in balloon-injured rat carotid arteries
32. Heme oxygenase-1 attenuates vascular remodeling following balloon injury in rat carotid arteries
33. -1 gene delivery inhibits injury-induced vascular neointima formation