Human IGF binding protein-3 overexpression impairs glucose regulation in mice via an inhibition of insulin secretion

Endocrinology

Volumn 152, Issue 6, 2011, Pages 2184-2196

  Nguyen, K Hoa ^a   Yao, Xing Hai ^a   Moulik, Saby ^a   Mishra, Suresh ^a   Nyomba, B L Grégoire ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARBACHOL; CYCLIC AMP; GLUCOSE; INSULIN; PHOSPHOGLYCERATE KINASE; PROTEIN KINASE B; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL FUNCTION; CELL ISOLATION; CELL TYPE; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; INCUBATION TIME; INSULIN CLEARANCE; INSULIN RELEASE; INSULIN RESPONSE; INSULIN TOLERANCE TEST; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WILD TYPE;

ANIMALS; DOWN-REGULATION; FEMALE; GENE EXPRESSION; GLUCOSE; GLUCOSE TOLERANCE TEST; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; ISLETS OF LANGERHANS; MICE; MICE, TRANSGENIC; PANCREAS;

EID: 79956327989     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-1324     Document Type: Article

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