Agonist-induced internalization of CC chemokine receptor 5 as a mechanism to inhibit HIV replication

Journal of Pharmacology and Experimental Therapeutics

Volumn 337, Issue 3, 2011, Pages 655-662

  Ferain, Thierry ^a   Hoveyda, Hamid ^a   Ooms, Frédéric ^b   Schols, Dominique ^c   Bernard, Jérôme ^a   Fraser, Graeme ^a  

^a Euroscreen SA   (Belgium)

^b Sopartec   (Belgium)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 CYANOPHENYL) N [1 [1 (N,1 DIPHENYLMETHYLSULFONAMIDO)PROPAN 2 YL]PIPERIDIN 4 YL]ACETAMIDE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIVIRUS AGENT; CHEMOKINE RECEPTOR CCR5; ESN 196; MARAVIROC; UNCLASSIFIED DRUG; YM 370749;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ANTIVIRAL RESISTANCE; ARTICLE; CELL STRAIN HEK293; CELL SURFACE; CHEMOTAXIS; CHO CELL; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; INTERNALIZATION; MACROPHAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; VIRUS CELL INTERACTION; VIRUS INHIBITION; VIRUS STRAIN;

ANIMALS; ANTI-HIV AGENTS; BENZENEACETAMIDES; CELL LINE; CHEMOKINE CCL5; CHEMOKINES; CHEMOTAXIS; CRICETINAE; CYCLOHEXANES; DNA REPLICATION; DRUG RESISTANCE, MULTIPLE, VIRAL; HEK293 CELLS; HIV INFECTIONS; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; PROTEIN BINDING; RECEPTORS, CCR5; RECEPTORS, CXCR4; SULFONAMIDES; TRIAZOLES; VIRUS REPLICATION;

EID: 79956226915     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.179622     Document Type: Article

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