-
1
-
-
4644227155
-
Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection
-
Balzarini, J., S. Hatse, K. Vermeire, K. Princen, S. Aquaro, C.-F Perno, E. De Clercq, H. Egberink, G. Vanden Mooter, W. Peumans, E. Van Damme, and D. Schols. 2004. Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection. Antimicrob. Agents Chemother. 48:3858-3870.
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 3858-3870
-
-
Balzarini, J.1
Hatse, S.2
Vermeire, K.3
Princen, K.4
Aquaro, S.5
Perno, C.-F.6
De Clercq, E.7
Egberink, H.8
Vanden Mooter, G.9
Peumans, W.10
Van Damme, E.11
Schols, D.12
-
2
-
-
4544256598
-
Profile of resistance of human immunodeficiency virus to mannose-specific plant lectins
-
Balzarini, J., K. Van Laethem, S. Hatse, K. Vermeire, E. De Clercq, W. Peumans, E. Van Damme, A.-M. Vandamme, A. Bolmstedt, and D. Schols. 2004. Profile of resistance of human immunodeficiency virus to mannose-specific plant lectins. J. Virol. 78:10617-10626.
-
(2004)
J. Virol.
, vol.78
, pp. 10617-10626
-
-
Balzarini, J.1
Van Laethem, K.2
Hatse, S.3
Vermeire, K.4
De Clercq, E.5
Peumans, W.6
Van Damme, E.7
Vandamme, A.-M.8
Bolmstedt, A.9
Schols, D.10
-
3
-
-
27144525215
-
Targeting the glycans of gp120: A novel approach aimed at the Achilles heel of HIV
-
Balzarini, J. 2005. Targeting the glycans of gp120: a novel approach aimed at the Achilles heel of HIV. Lancet Infect. Dis. 5:726-731.
-
(2005)
Lancet Infect. Dis.
, vol.5
, pp. 726-731
-
-
Balzarini, J.1
-
4
-
-
17844397160
-
Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis
-
Balzarini, J., K. Van Laethem, S. Hatse, M. Froeyen, E. Van Damme, W. Peumans, E. De Clercq, and D. Schols. 2005. Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis. Mol. Pharmacol. 67:1556-1565.
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 1556-1565
-
-
Balzarini, J.1
Van Laethem, K.2
Hatse, S.3
Froeyen, M.4
Van Damme, E.5
Peumans, W.6
De Clercq, E.7
Schols, D.8
-
5
-
-
28844481759
-
Carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in HIV gp120. A new therapeutic concept to hit the Achilles heel of HIV
-
Balzarini, J., K. Van Laethem, S. Hatse, M. Froeyen, W. Peumans, E. Van Damme, and D. Schols. 2005. Carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in HIV gp120. A new therapeutic concept to hit the Achilles heel of HIV. J. Biol. Chem. 280:41005-41014.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 41005-41014
-
-
Balzarini, J.1
Van Laethem, K.2
Hatse, S.3
Froeyen, M.4
Peumans, W.5
Van Damme, E.6
Schols, D.7
-
6
-
-
33748638894
-
Chemotherapy of human immunodeficiency virus by pradimicin A: A novel therapeutic concept for treatment of glycosylated enveloped viruses
-
abstr. 6
-
Balzarini, J., K. Van Laethem, S. Hatse, A. Bugatti, M. Rusnati, S. Aquaro, C.-F. Perno, Y. Igarashi, T. Oki, and D. Schols. 2006. Chemotherapy of human immunodeficiency virus by pradimicin A: a novel therapeutic concept for treatment of glycosylated enveloped viruses. Abstr. 19th Int. Conf. Antivir. Res., abstr. 6.
-
(2006)
Abstr. 19th Int. Conf. Antivir. Res.
-
-
Balzarini, J.1
Van Laethem, K.2
Hatse, S.3
Bugatti, A.4
Rusnati, M.5
Aquaro, S.6
Perno, C.-F.7
Igarashi, Y.8
Oki, T.9
Schols, D.10
-
7
-
-
33748665819
-
Large-molecular-weight carbohydrate-binding agents as HIV entry inhibitors targeting glycoprotein gp120
-
in press
-
Balzarini, J. Large-molecular-weight carbohydrate-binding agents as HIV entry inhibitors targeting glycoprotein gp120. Curr. Opin. HIV AIDS, in press.
-
Curr. Opin. HIV AIDS
-
-
Balzarini, J.1
-
8
-
-
0031848334
-
Solution structure of cyanovirin-N, a potent HIV-inactivating protein
-
Bewley, C. A., K. R. Gustafson, M. R. Boyd, D. G. Covell, A. Bax, G. M. Clore, and A. M. Gronenborn. 1998. Solution structure of cyanovirin-N, a potent HIV-inactivating protein. Nat. Struct. Biol. 5:571-578.
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 571-578
-
-
Bewley, C.A.1
Gustafson, K.R.2
Boyd, M.R.3
Covell, D.G.4
Bax, A.5
Clore, G.M.6
Gronenborn, A.M.7
-
9
-
-
0034791996
-
Solution structure of a cyanovirin-N:Man alpha 1-2Man alpha complex: Structural basis for high-affinity carbohydrate-mediated binding to gp120
-
Bewley, C. A. 2001. Solution structure of a cyanovirin-N:Man alpha 1-2Man alpha complex: structural basis for high-affinity carbohydrate-mediated binding to gp120. Structure 9:931-940.
-
(2001)
Structure
, vol.9
, pp. 931-940
-
-
Bewley, C.A.1
-
10
-
-
0036389940
-
Site-specific discrimination by cyanovirin-N for α-linked trisaccharides comprising the three arms of Man(8) and Man(9)
-
Bewley, C. A., S. Kiyonaka, and I. Hamachi. 2002. Site-specific discrimination by cyanovirin-N for α-linked trisaccharides comprising the three arms of Man(8) and Man(9). J. Mol. Biol. 322:881-889.
-
(2002)
J. Mol. Biol.
, vol.322
, pp. 881-889
-
-
Bewley, C.A.1
Kiyonaka, S.2
Hamachi, I.3
-
11
-
-
0035028207
-
Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner
-
Bolmstedt, A. J., B. R. O'Keefe, S. R. Shenoy, J. B. McMahon, and M. R. Boyd. 2001. Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner. Mol. Pharmacol. 59:949-954.
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 949-954
-
-
Bolmstedt, A.J.1
O'Keefe, B.R.2
Shenoy, S.R.3
McMahon, J.B.4
Boyd, M.R.5
-
12
-
-
0037072880
-
Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
-
Botos, I., B. R. O'Keefe, S. R. Shenoy, L. K. Cartner, D. M. Ratner, P. H. Seeberger, M. R. Boyd, and A. Wlodawer. 2002. Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides. J. Biol. Chem. 277:34336-34342.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34336-34342
-
-
Botos, I.1
O'Keefe, B.R.2
Shenoy, S.R.3
Cartner, L.K.4
Ratner, D.M.5
Seeberger, P.H.6
Boyd, M.R.7
Wlodawer, A.8
-
13
-
-
0030790094
-
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: Potential applications to microbicide development
-
Boyd, M. R., K. R. Gustafson, J. B. McMahon, R. H. Shoemaker, B. R. O'Keefe, T. Mori, R. J. Gulakowski, L. Wu, M. I. Rivera, C. M. Laurencot, M. J. Currens, J. H. Cardellina II, R. W. Buckheit, Jr, P. L. Nara, L. K. Pannell, R. C. Sowder II, and L. E. Henderson. 1997. Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development. Antimicrob. Agents Chemother. 41:1521-1530.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1521-1530
-
-
Boyd, M.R.1
Gustafson, K.R.2
McMahon, J.B.3
Shoemaker, R.H.4
O'Keefe, B.R.5
Mori, T.6
Gulakowski, R.J.7
Wu, L.8
Rivera, M.I.9
Laurencot, C.M.10
Currens, M.J.11
Cardellina II, J.H.12
Buckheit Jr., R.W.13
Nara, P.L.14
Pannell, L.K.15
Sowder II, R.C.16
Henderson, L.E.17
-
14
-
-
12444291017
-
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition
-
Calarese, D. A, C. N. Scanlan, M. B. Zwick, S. Deechongkit, Y. Mimura, R. Kunert, P. Zhu, M. R. Wormald, R. L. Stanfield, K. H. Roux, J. W. Kelly, P. M. Rudd, R. A. Dwek, H. Katinger, D. R. Buron, and I. A. Wilson. 2003. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science 300:2065-2071.
-
(2003)
Science
, vol.300
, pp. 2065-2071
-
-
Calarese, D.A.1
Scanlan, C.N.2
Zwick, M.B.3
Deechongkit, S.4
Mimura, Y.5
Kunert, R.6
Zhu, P.7
Wormald, M.R.8
Stanfield, R.L.9
Roux, K.H.10
Kelly, J.W.11
Rudd, P.M.12
Dwek, R.A.13
Katinger, H.14
Buron, D.R.15
Wilson, I.A.16
-
15
-
-
0036052503
-
Targetting glycosylation as a therapeutic approach
-
Dwek, R. A., T. D. Butters, F. M. Platt, and N. Zitzmann. 2002. Targetting glycosylation as a therapeutic approach. Nat. Rev. Drug Discov. 1:65-75.
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 65-75
-
-
Dwek, R.A.1
Butters, T.D.2
Platt, F.M.3
Zitzmann, N.4
-
16
-
-
0028966224
-
A general model for the surface glycoproteins of HIV and other retroviruses
-
Gallaher, W. R., J. M. Ball, R. F. Garry, A. M. Martin-Amedee, and R. C. Montelaro. 1995. A general model for the surface glycoproteins of HIV and other retroviruses. AIDS Res. Hum. Retrovir. 11:191-202.
-
(1995)
AIDS Res. Hum. Retrovir.
, vol.11
, pp. 191-202
-
-
Gallaher, W.R.1
Ball, J.M.2
Garry, R.F.3
Martin-Amedee, A.M.4
Montelaro, R.C.5
-
17
-
-
0037024754
-
The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1
-
Giomarelli, B., R. Prowedi, F. Meacci, T. Maggi, D. Medaglinl, G. Pozzi, T. Mori, J. B. McMahon, R. Gardella, and M. R. Boyd. 2002. The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1. AIDS 16:1351-1356.
-
(2002)
AIDS
, vol.16
, pp. 1351-1356
-
-
Giomarelli, B.1
Prowedi, R.2
Meacci, F.3
Maggi, T.4
Medaglinl, D.5
Pozzi, G.6
Mori, T.7
McMahon, J.B.8
Gardella, R.9
Boyd, M.R.10
-
18
-
-
27744597054
-
Structure of a V3-containing HIV-1 gp120 core
-
Huang, C. C., M. Tang, M. Y. Zhang, S. Majeed, E. Montabana, R. L. Stanfield, D. S. Dimitrov, B. Korber, J. Sodroski, I. A. Wilson, R. Wyatt, and P. D. Kwong. 2005. Structure of a V3-containing HIV-1 gp120 core. Science 310:1025-1028.
-
(2005)
Science
, vol.310
, pp. 1025-1028
-
-
Huang, C.C.1
Tang, M.2
Zhang, M.Y.3
Majeed, S.4
Montabana, E.5
Stanfield, R.L.6
Dimitrov, D.S.7
Korber, B.8
Sodroski, J.9
Wilson, I.A.10
Wyatt, R.11
Kwong, P.D.12
-
19
-
-
0032543307
-
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
Kwong, P. D., R. Wyatt, J. Robinson, R. W. Sweet, J. Sodroski, and W. A. Hendrickson. 1998. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 393:648-659.
-
(1998)
Nature
, vol.393
, pp. 648-659
-
-
Kwong, P.D.1
Wyatt, R.2
Robinson, J.3
Sweet, R.W.4
Sodroski, J.5
Hendrickson, W.A.6
-
20
-
-
33748649335
-
Development of vaginal lactobacilli for mucosal delivery of a topical microbicide, cyanovirin-N (CV-N)
-
abstr. S93
-
Lagenaur, L. A., X. Liu, D. A. Simpson, K. Essenmacher, C. Parker, C.-H. Chang, D. Tsai, S. Rao, D. Hamer, T. P. Parks, P. P. Lee, and Q. Xu. 2005. Development of vaginal lactobacilli for mucosal delivery of a topical microbicide, cyanovirin-N (CV-N). Abstr. Int. Meet. Inst. Hum. Virol., abstr. S93.
-
(2005)
Abstr. Int. Meet. Inst. Hum. Virol.
-
-
Lagenaur, L.A.1
Liu, X.2
Simpson, D.A.3
Essenmacher, K.4
Parker, C.5
Chang, C.-H.6
Tsai, D.7
Rao, S.8
Hamer, D.9
Parks, T.P.10
Lee, P.P.11
Xu, Q.12
-
21
-
-
0025292252
-
Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells
-
Leonard, C. K., M. W. Spellman, L. Riddle, R. J. Harris, J. N. Thomas, and T. J. Gregory. 1990. Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. J. Biol. Chem. 265:10373-10382.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 10373-10382
-
-
Leonard, C.K.1
Spellman, M.W.2
Riddle, L.3
Harris, R.J.4
Thomas, J.N.5
Gregory, T.J.6
-
22
-
-
0031559753
-
-
Mori, T., R. H. Shoemaker, R. J. Gulakowski, B. L. Krepps, J. B. McMahon, K. R. Gustafson, L. K. Pannell, and M. R. Boyd. 1997. Biochem. Biophys. Res. Commun. 238:218-222.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.238
, pp. 218-222
-
-
Mori, T.1
Shoemaker, R.H.2
Gulakowski, R.J.3
Krepps, B.L.4
McMahon, J.B.5
Gustafson, K.R.6
Pannell, L.K.7
Boyd, M.R.8
-
23
-
-
18244422922
-
The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha 1→2 mannose residues on the outer face of gp120
-
Scanlan, C. N., R. Pantophlet, M. R. Wormald, S. E. Ollmann, R. Stanfield, I. A. Wilson, H. Katinger, R. A. Dwek, P. M. Rudd, and D. R. Burton. 2002. The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha 1→2 mannose residues on the outer face of gp120. J. Virol. 76:7306-7321.
-
(2002)
J. Virol.
, vol.76
, pp. 7306-7321
-
-
Scanlan, C.N.1
Pantophlet, R.2
Wormald, M.R.3
Ollmann, S.E.4
Stanfield, R.5
Wilson, I.A.6
Katinger, H.7
Dwek, R.A.8
Rudd, P.M.9
Burton, D.R.10
-
24
-
-
33748671642
-
-
Sharon, N., and H. Lis (ed.). Kluwer Academic Publishers, Dordrecht, The Netherlands
-
Sharon, N., and H. Lis (ed.). 2003. Lectins, 2nd ed. Kluwer Academic Publishers, Dordrecht, The Netherlands.
-
(2003)
Lectins, 2nd Ed.
-
-
-
25
-
-
0742272702
-
Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models
-
Tsai, C. C., P. Emau, Y. Jiang, M. B. Agy, R. J. Shattock, A. Schmidt, W. R. Morton, K. R. Gustafson, and M. R. Boyd. 2004. Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models. AIDS Res. Hum. Retrovir. 20:11-18.
-
(2004)
AIDS Res. Hum. Retrovir.
, vol.20
, pp. 11-18
-
-
Tsai, C.C.1
Emau, P.2
Jiang, Y.3
Agy, M.B.4
Shattock, R.J.5
Schmidt, A.6
Morton, W.R.7
Gustafson, K.R.8
Boyd, M.R.9
-
26
-
-
0001666483
-
Leaves of the orchid twayblade (Listera ovata) contain a mannose-specific lectin
-
Van Damme, E. J. M., A. K. Allen, and W. J. Peumans. 1987. Leaves of the orchid twayblade (Listera ovata) contain a mannose-specific lectin. Plant Physiol. 85:566-569.
-
(1987)
Plant Physiol.
, vol.85
, pp. 566-569
-
-
Van Damme, E.J.M.1
Allen, A.K.2
Peumans, W.J.3
-
27
-
-
0003034009
-
Related mannose-specific lectins from different species of the family Amaryllidaceae
-
Van Damme, E. J. M., A. K. Allen, and W. J. Peumans. 1988. Related mannose-specific lectins from different species of the family Amaryllidaceae. Physiol. Plant 73:52-57.
-
(1988)
Physiol. Plant
, vol.73
, pp. 52-57
-
-
Van Damme, E.J.M.1
Allen, A.K.2
Peumans, W.J.3
-
28
-
-
0003643745
-
-
Van Damme, E. J. M., W. J. Peumans, A. Pusztai, and S. Bardocz (ed.). John Wiley & Sons, Chichester, United Kingdom
-
Van Damme, E. J. M., W. J. Peumans, A. Pusztai, and S. Bardocz (ed.). 1998. Handbook of plant lectins: properties and biomedical applications. John Wiley & Sons, Chichester, United Kingdom.
-
(1998)
Handbook of Plant Lectins: Properties and Biomedical Applications
-
-
-
29
-
-
9944239729
-
A genotypic resistance assay for the detection of drug resistance in the human immunodeficiency virus type 1 envelope gene
-
Van Laethem, K., Y. Schrooten, P. Lemey, E. Van Wijngaerden, S. De Wit, M. Van Ranst, and A.-M. Vandamme. 2005. A genotypic resistance assay for the detection of drug resistance in the human immunodeficiency virus type 1 envelope gene. J. Virol. Methods 123:25-34.
-
(2005)
J. Virol. Methods
, vol.123
, pp. 25-34
-
-
Van Laethem, K.1
Schrooten, Y.2
Lemey, P.3
Van Wijngaerden, E.4
De Wit, S.5
Van Ranst, M.6
Vandamme, A.-M.7
-
30
-
-
23844475790
-
2: Structural basis for specificity and high-affinity binding to the core pentasaccharide from N-linked oligomannoside
-
2: structural basis for specificity and high-affinity binding to the core pentasaccharide from N-linked oligomannoside. J. Biol. Chem. 280:29269-29276.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29269-29276
-
-
Williams Jr., D.C.1
Lee, J.Y.2
Cai, M.3
Bewley, C.A.4
Clore, G.M.5
-
31
-
-
19944403933
-
Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A
-
Witvrouw, M., V. Fikkert, A. Hantson, C. Pannecouque, B. R. O'Keefe, J. McMahon, L. Stamatatos, E. De Clercq, and A. Bolmstedt. 2005. Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A. J. Virol. 79:7777-7784.
-
(2005)
J. Virol.
, vol.79
, pp. 7777-7784
-
-
Witvrouw, M.1
Fikkert, V.2
Hantson, A.3
Pannecouque, C.4
O'Keefe, B.R.5
McMahon, J.6
Stamatatos, L.7
De Clercq, E.8
Bolmstedt, A.9
-
32
-
-
0032543555
-
The antigenic structure of the HIV gp120 envelope glycoprotein
-
Wyatt, R., P. D. Kwong, E. Desjardins, R. W. Sweet, J. Robinson, W. A. Hendrickson, and J. G. Sodroski. 1998. The antigenic structure of the HIV gp120 envelope glycoprotein. Nature 393:705-711.
-
(1998)
Nature
, vol.393
, pp. 705-711
-
-
Wyatt, R.1
Kwong, P.D.2
Desjardins, E.3
Sweet, R.W.4
Robinson, J.5
Hendrickson, W.A.6
Sodroski, J.G.7
-
33
-
-
0033532212
-
Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping
-
Yang, F., C. A. Bewley, J. M. Louis, K. R. Gustafson, M. R. Boyd, A. M. Gronenborn, M. Clore, and A. Wlodawer. 1999. Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping. J. Mol. Biol. 288:403-412.
-
(1999)
J. Mol. Biol.
, vol.288
, pp. 403-412
-
-
Yang, F.1
Bewley, C.A.2
Louis, J.M.3
Gustafson, K.R.4
Boyd, M.R.5
Gronenborn, A.M.6
Clore, M.7
Wlodawer, A.8
|