메뉴 건너뛰기




Volumn 6, Issue 5, 2011, Pages

P130cas attenuates epidermal growth factor (EGF) receptor internalization by modulating EGF-triggered dynamin phosphorylation

Author keywords

[No Author keywords available]

Indexed keywords

CRK ASSOCIATED SUBSTRATE PROTEIN; DYNAMIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBRONECTIN; PROTEIN SH3;

EID: 79956222908     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020125     Document Type: Article
Times cited : (8)

References (46)
  • 2
    • 33751328082 scopus 로고    scopus 로고
    • ErbB receptors: new insights on mechanisms and biology
    • Linggi B, Carpenter G, (2006) ErbB receptors: new insights on mechanisms and biology. Trends Cell Biol 16: 649-656.
    • (2006) Trends Cell Biol , vol.16 , pp. 649-656
    • Linggi, B.1    Carpenter, G.2
  • 3
    • 77956268839 scopus 로고    scopus 로고
    • Understanding resistance to EGFR inhibitors-impact on future treatment strategies
    • Wheeler DL, Dunn EF, Harari PM, (2010) Understanding resistance to EGFR inhibitors-impact on future treatment strategies. Nat Rev Clin Oncol 7: 493-507.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 493-507
    • Wheeler, D.L.1    Dunn, E.F.2    Harari, P.M.3
  • 4
    • 67549145398 scopus 로고    scopus 로고
    • Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment
    • Jura N, Endres NF, Engel K, Deindl S, Das R, et al. (2009) Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell 137: 1293-1307.
    • (2009) Cell , vol.137 , pp. 1293-1307
    • Jura, N.1    Endres, N.F.2    Engel, K.3    Deindl, S.4    Das, R.5
  • 5
    • 0036787904 scopus 로고    scopus 로고
    • Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival
    • Wang Y, Pennock S, Chen X, Wang Z, (2002) Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival. Mol Cell Biol 22: 7279-7290.
    • (2002) Mol Cell Biol , vol.22 , pp. 7279-7290
    • Wang, Y.1    Pennock, S.2    Chen, X.3    Wang, Z.4
  • 6
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: the complexity of targeted inhibitors
    • Hynes NE, Lane HA, (2005) ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 5: 341-354.
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 8
    • 0035162703 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking
    • Burke P, Schooler K, Wiley HS, (2001) Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking. Mol Biol Cell 12: 1897-1910.
    • (2001) Mol Biol Cell , vol.12 , pp. 1897-1910
    • Burke, P.1    Schooler, K.2    Wiley, H.S.3
  • 9
    • 33847260172 scopus 로고    scopus 로고
    • Spatial regulation of EGFR signaling by Sprouty2
    • Kim HJ, Taylor LJ, Bar-Sagi D, (2007) Spatial regulation of EGFR signaling by Sprouty2. Curr Biol 17: 455-461.
    • (2007) Curr Biol , vol.17 , pp. 455-461
    • Kim, H.J.1    Taylor, L.J.2    Bar-Sagi, D.3
  • 10
    • 38349052961 scopus 로고    scopus 로고
    • hSef potentiates EGF-mediated MAPK signaling through affecting EGFR trafficking and degradation
    • Ren Y, Cheng L, Rong Z, Li Z, Li Y, et al. (2008) hSef potentiates EGF-mediated MAPK signaling through affecting EGFR trafficking and degradation. Cell Signal 20: 518-533.
    • (2008) Cell Signal , vol.20 , pp. 518-533
    • Ren, Y.1    Cheng, L.2    Rong, Z.3    Li, Z.4    Li, Y.5
  • 11
    • 77953167957 scopus 로고    scopus 로고
    • Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor
    • Goh LK, Huang F, Kim W, Gygi S, Sorkin A, (2010) Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor. J Cell Biol 189: 871-883.
    • (2010) J Cell Biol , vol.189 , pp. 871-883
    • Goh, L.K.1    Huang, F.2    Kim, W.3    Gygi, S.4    Sorkin, A.5
  • 12
    • 67649889124 scopus 로고    scopus 로고
    • Differential effects of EGFR ligands on endocytic sorting of the receptor
    • Roepstorff K, Grandal MV, Henriksen L, Knudsen SL, Lerdrup M, et al. (2009) Differential effects of EGFR ligands on endocytic sorting of the receptor. Traffic 10: 1115-1127.
    • (2009) Traffic , vol.10 , pp. 1115-1127
    • Roepstorff, K.1    Grandal, M.V.2    Henriksen, L.3    Knudsen, S.L.4    Lerdrup, M.5
  • 13
    • 48549088895 scopus 로고    scopus 로고
    • Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation
    • Sigismund S, Argenzio E, Tosoni D, Cavallaro E, Polo S, et al. (2008) Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation. Dev Cell 15: 209-219.
    • (2008) Dev Cell , vol.15 , pp. 209-219
    • Sigismund, S.1    Argenzio, E.2    Tosoni, D.3    Cavallaro, E.4    Polo, S.5
  • 14
    • 69249137477 scopus 로고    scopus 로고
    • Endocytosis and signalling: intertwining molecular networks
    • Sorkin A, von Zastrow M, (2009) Endocytosis and signalling: intertwining molecular networks. Nat Rev Mol Cell Biol 10: 609-622.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 609-622
    • Sorkin, A.1    von Zastrow, M.2
  • 15
    • 0742288598 scopus 로고    scopus 로고
    • The dynamin superfamily: universal membrane tubulation and fission molecules?
    • Praefcke GJ, McMahon HT, (2004) The dynamin superfamily: universal membrane tubulation and fission molecules? Nat Rev Mol Cell Biol 5: 133-147.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 133-147
    • Praefcke, G.J.1    McMahon, H.T.2
  • 16
    • 0035874483 scopus 로고    scopus 로고
    • Heterodimerization of the epidermal-growth-factor (EGF) receptor and ErbB2 and the affinity of EGF binding are regulated by different mechanisms
    • Johannessen LE, Haugen KE, ostvold AC, Stang E, Madshus IH, (2001) Heterodimerization of the epidermal-growth-factor (EGF) receptor and ErbB2 and the affinity of EGF binding are regulated by different mechanisms. Biochem J 356: 87-96.
    • (2001) Biochem J , vol.356 , pp. 87-96
    • Johannessen, L.E.1    Haugen, K.E.2    Ostvold, A.C.3    Stang, E.4    Madshus, I.H.5
  • 17
    • 0033544953 scopus 로고    scopus 로고
    • Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase
    • Kranenburg O, Verlaan I, Moolenaar WH, (1999) Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase. J Biol Chem 274: 35301-35304.
    • (1999) J Biol Chem , vol.274 , pp. 35301-35304
    • Kranenburg, O.1    Verlaan, I.2    Moolenaar, W.H.3
  • 18
    • 77951877243 scopus 로고    scopus 로고
    • VAV2 regulates epidermal growth factor receptor endocytosis and degradation
    • Thalappilly S, Soubeyran P, Iovanna JL, Dusetti NJ, (2010) VAV2 regulates epidermal growth factor receptor endocytosis and degradation. Oncogene 29: 2528-2539.
    • (2010) Oncogene , vol.29 , pp. 2528-2539
    • Thalappilly, S.1    Soubeyran, P.2    Iovanna, J.L.3    Dusetti, N.J.4
  • 19
    • 0141756154 scopus 로고    scopus 로고
    • Interactions between growth factor receptors and adhesion molecules: breaking the rules
    • Comoglio PM, Boccaccio C, Trusolino L, (2003) Interactions between growth factor receptors and adhesion molecules: breaking the rules. Curr Opin Cell Biol 15: 565-571.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 565-571
    • Comoglio, P.M.1    Boccaccio, C.2    Trusolino, L.3
  • 20
    • 0037088647 scopus 로고    scopus 로고
    • Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines
    • Moro L, Dolce L, Cabodi S, Bergatto E, Erba EB, et al. (2002) Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines. J Biol Chem 277: 9405-9414.
    • (2002) J Biol Chem , vol.277 , pp. 9405-9414
    • Moro, L.1    Dolce, L.2    Cabodi, S.3    Bergatto, E.4    Erba, E.B.5
  • 21
    • 4544302236 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells
    • Bill HM, Knudsen B, Moores SL, Muthuswamy SK, Rao VR, et al. (2004) Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells. Mol Cell Biol 24: 8586-8599.
    • (2004) Mol Cell Biol , vol.24 , pp. 8586-8599
    • Bill, H.M.1    Knudsen, B.2    Moores, S.L.3    Muthuswamy, S.K.4    Rao, V.R.5
  • 22
    • 33646557326 scopus 로고    scopus 로고
    • p130Cas: a versatile scaffold in signaling networks
    • Defilippi P, Di Stefano P, Cabodi S, (2006) p130Cas: a versatile scaffold in signaling networks. Trends Cell Biol 16: 257-263.
    • (2006) Trends Cell Biol , vol.16 , pp. 257-263
    • Defilippi, P.1    Di Stefano, P.2    Cabodi, S.3
  • 24
    • 0035474419 scopus 로고    scopus 로고
    • Functions of the adapter protein Cas: signal convergence and the determination of cellular responses
    • Bouton AH, Riggins RB, Bruce-Staskal PJ, (2001) Functions of the adapter protein Cas: signal convergence and the determination of cellular responses. Oncogene 20: 6448-6458.
    • (2001) Oncogene , vol.20 , pp. 6448-6458
    • Bouton, A.H.1    Riggins, R.B.2    Bruce-Staskal, P.J.3
  • 25
    • 4644305806 scopus 로고    scopus 로고
    • Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration
    • Shin NY, Dise RS, Schneider-Mergener J, Ritchie MD, Kilkenny DM, et al. (2004) Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration. J Biol Chem 279: 38331-38337.
    • (2004) J Biol Chem , vol.279 , pp. 38331-38337
    • Shin, N.Y.1    Dise, R.S.2    Schneider-Mergener, J.3    Ritchie, M.D.4    Kilkenny, D.M.5
  • 26
    • 78149441694 scopus 로고    scopus 로고
    • P130Cas Src-binding and substrate domains have distinct roles in sustaining focal adhesion disassembly and promoting cell migration
    • Meenderink LM, Ryzhova LM, Donato DM, Gochberg DF, Kaverina I, et al. (2010) P130Cas Src-binding and substrate domains have distinct roles in sustaining focal adhesion disassembly and promoting cell migration. PLoS One 5: e13412.
    • (2010) PLoS One , vol.5
    • Meenderink, L.M.1    Ryzhova, L.M.2    Donato, D.M.3    Gochberg, D.F.4    Kaverina, I.5
  • 27
    • 33746883110 scopus 로고    scopus 로고
    • Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b
    • Riggins RB, Thomas KS, Ta HQ, Wen J, Davis RJ, et al. (2006) Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b. Cancer Res 66: 7007-7015.
    • (2006) Cancer Res , vol.66 , pp. 7007-7015
    • Riggins, R.B.1    Thomas, K.S.2    Ta, H.Q.3    Wen, J.4    Davis, R.J.5
  • 28
    • 70450225242 scopus 로고    scopus 로고
    • Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor
    • Liu NS, Loo LS, Loh E, Seet LF, Hong W, (2009) Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor. Embo J 28: 3485-3499.
    • (2009) Embo J , vol.28 , pp. 3485-3499
    • Liu, N.S.1    Loo, L.S.2    Loh, E.3    Seet, L.F.4    Hong, W.5
  • 29
    • 0037135528 scopus 로고    scopus 로고
    • Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor
    • Ahn S, Kim J, Lucaveche CL, Reedy MC, Luttrell LM, et al. (2002) Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor. J Biol Chem 277: 26642-26651.
    • (2002) J Biol Chem , vol.277 , pp. 26642-26651
    • Ahn, S.1    Kim, J.2    Lucaveche, C.L.3    Reedy, M.C.4    Luttrell, L.M.5
  • 30
    • 33846786829 scopus 로고    scopus 로고
    • Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes
    • Lie PP, Xia W, Wang CQ, Mruk DD, Yan HH, et al. (2006) Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes. J Endocrinol 191: 571-586.
    • (2006) J Endocrinol , vol.191 , pp. 571-586
    • Lie, P.P.1    Xia, W.2    Wang, C.Q.3    Mruk, D.D.4    Yan, H.H.5
  • 31
    • 0034597062 scopus 로고    scopus 로고
    • Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape
    • McNiven MA, Kim L, Krueger EW, Orth JD, Cao H, et al. (2000) Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape. J Cell Biol 151: 187-198.
    • (2000) J Cell Biol , vol.151 , pp. 187-198
    • McNiven, M.A.1    Kim, L.2    Krueger, E.W.3    Orth, J.D.4    Cao, H.5
  • 32
    • 36749036679 scopus 로고    scopus 로고
    • EGF receptor ubiquitination is not necessary for its internalization
    • Huang F, Goh LK, Sorkin A, (2007) EGF receptor ubiquitination is not necessary for its internalization. Proc Natl Acad Sci U S A 104: 16904-16909.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 16904-16909
    • Huang, F.1    Goh, L.K.2    Sorkin, A.3
  • 33
    • 3442879850 scopus 로고    scopus 로고
    • Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways
    • Lee JW, Juliano R, (2004) Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways. Mol Cells 17: 188-202.
    • (2004) Mol Cells , vol.17 , pp. 188-202
    • Lee, J.W.1    Juliano, R.2
  • 34
    • 0037339887 scopus 로고    scopus 로고
    • Grb2 regulates internalization of EGF receptors through clathrin-coated pits
    • Jiang X, Huang F, Marusyk A, Sorkin A, (2003) Grb2 regulates internalization of EGF receptors through clathrin-coated pits. Mol Biol Cell 14: 858-870.
    • (2003) Mol Biol Cell , vol.14 , pp. 858-870
    • Jiang, X.1    Huang, F.2    Marusyk, A.3    Sorkin, A.4
  • 35
    • 7944237784 scopus 로고    scopus 로고
    • The interplay between Src family kinases and receptor tyrosine kinases
    • Bromann PA, Korkaya H, Courtneidge SA, (2004) The interplay between Src family kinases and receptor tyrosine kinases. Oncogene 23: 7957-7968.
    • (2004) Oncogene , vol.23 , pp. 7957-7968
    • Bromann, P.A.1    Korkaya, H.2    Courtneidge, S.A.3
  • 36
    • 0029034939 scopus 로고
    • c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism
    • Kaplan KB, Swedlow JR, Morgan DO, Varmus HE, (1995) c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism. Genes Dev 9: 1505-1517.
    • (1995) Genes Dev , vol.9 , pp. 1505-1517
    • Kaplan, K.B.1    Swedlow, J.R.2    Morgan, D.O.3    Varmus, H.E.4
  • 39
    • 75149163629 scopus 로고    scopus 로고
    • SRC-mediated phosphorylation of dynamin and cortactin regulates the "constitutive" endocytosis of transferrin
    • Cao H, Chen J, Krueger EW, McNiven MA, (2010) SRC-mediated phosphorylation of dynamin and cortactin regulates the "constitutive" endocytosis of transferrin. Mol Cell Biol 30: 781-792.
    • (2010) Mol Cell Biol , vol.30 , pp. 781-792
    • Cao, H.1    Chen, J.2    Krueger, E.W.3    McNiven, M.A.4
  • 40
    • 0033555946 scopus 로고    scopus 로고
    • Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling
    • Ahn S, Maudsley S, Luttrell LM, Lefkowitz RJ, Daaka Y, (1999) Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. J Biol Chem 274: 1185-1188.
    • (1999) J Biol Chem , vol.274 , pp. 1185-1188
    • Ahn, S.1    Maudsley, S.2    Luttrell, L.M.3    Lefkowitz, R.J.4    Daaka, Y.5
  • 41
    • 0027990414 scopus 로고
    • A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner
    • Sakai R, Iwamatsu A, Hirano N, Ogawa S, Tanaka T, et al. (1994) A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner. Embo J 13: 3748-3756.
    • (1994) Embo J , vol.13 , pp. 3748-3756
    • Sakai, R.1    Iwamatsu, A.2    Hirano, N.3    Ogawa, S.4    Tanaka, T.5
  • 42
    • 1542319711 scopus 로고    scopus 로고
    • The 31-kDa caspase-generated cleavage product of p130cas functions as a transcriptional repressor of E2A in apoptotic cells
    • Kim W, Kook S, Kim DJ, Teodorof C, Song WK, (2004) The 31-kDa caspase-generated cleavage product of p130cas functions as a transcriptional repressor of E2A in apoptotic cells. J Biol Chem 279: 8333-8342.
    • (2004) J Biol Chem , vol.279 , pp. 8333-8342
    • Kim, W.1    Kook, S.2    Kim, D.J.3    Teodorof, C.4    Song, W.K.5
  • 43
    • 48249136081 scopus 로고    scopus 로고
    • The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling
    • Kim W, Seok Kang Y, Soo Kim J, Shin NY, Hanks SK, et al. (2008) The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling. Mol Biol Cell 19: 2135-2146.
    • (2008) Mol Biol Cell , vol.19 , pp. 2135-2146
    • Kim, W.1    Seok Kang, Y.2    Soo Kim, J.3    Shin, N.Y.4    Hanks, S.K.5
  • 44
    • 23344448598 scopus 로고    scopus 로고
    • Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells
    • Hamamura K, Furukawa K, Hayashi T, Hattori T, Nakano J, et al. (2005) Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc Natl Acad Sci U S A 102: 11041-11046.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11041-11046
    • Hamamura, K.1    Furukawa, K.2    Hayashi, T.3    Hattori, T.4    Nakano, J.5
  • 45
    • 0342470471 scopus 로고    scopus 로고
    • Caspase-mediated cleavage of p130cas in etoposide-induced apoptotic Rat-1 cells
    • Kook S, Shim SR, Choi SJ, Ahnn J, Kim JI, et al. (2000) Caspase-mediated cleavage of p130cas in etoposide-induced apoptotic Rat-1 cells. Mol Biol Cell 11: 929-939.
    • (2000) Mol Biol Cell , vol.11 , pp. 929-939
    • Kook, S.1    Shim, S.R.2    Choi, S.J.3    Ahnn, J.4    Kim, J.I.5
  • 46
    • 0032948524 scopus 로고    scopus 로고
    • Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation
    • Wang Z, Zhang L, Yeung TK, Chen X, (1999) Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation. Mol Biol Cell 10: 1621-1636.
    • (1999) Mol Biol Cell , vol.10 , pp. 1621-1636
    • Wang, Z.1    Zhang, L.2    Yeung, T.K.3    Chen, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.