메뉴 건너뛰기




Volumn 10, Issue 5, 1999, Pages 1621-1636

Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR RECEPTOR;

EID: 0032948524     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.10.5.1621     Document Type: Article
Times cited : (159)

References (65)
  • 1
    • 0030728295 scopus 로고    scopus 로고
    • Distinct endocytic responses of heteromeric and homomeric transforming growth factor beta receptors
    • Anders, R.A., Arline, S.L., Dore, J.J., and Leof, E.B. (1997). Distinct endocytic responses of heteromeric and homomeric transforming growth factor beta receptors. Mol. Biol. Cell 8, 2133-2143.
    • (1997) Mol. Biol. Cell , vol.8 , pp. 2133-2143
    • Anders, R.A.1    Arline, S.L.2    Dore, J.J.3    Leof, E.B.4
  • 2
    • 0025681492 scopus 로고
    • Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors
    • Anderson, D., Koch, C.A., Gray, L., Ellis, C., Moran, M.F., and Pawson, T. (1990). Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors. Science 250, 979-982.
    • (1990) Science , vol.250 , pp. 979-982
    • Anderson, D.1    Koch, C.A.2    Gray, L.3    Ellis, C.4    Moran, M.F.5    Pawson, T.6
  • 3
    • 0022485548 scopus 로고
    • Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185
    • Bargmann, C.I., Hung, M.C., and Weinberg, R.A. (1986). Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Cell 45, 649-657.
    • (1986) Cell , vol.45 , pp. 649-657
    • Bargmann, C.I.1    Hung, M.C.2    Weinberg, R.A.3
  • 4
    • 0029912203 scopus 로고    scopus 로고
    • All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired
    • Baulida, J., Kraus, M.H., Alimandi, M., Di Fiore, P.P., and Carpenter, G. (1996). All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J. Biol. Chem. 271, 5251-5257.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5251-5257
    • Baulida, J.1    Kraus, M.H.2    Alimandi, M.3    Di Fiore, P.P.4    Carpenter, G.5
  • 5
    • 0023082137 scopus 로고
    • Receptors for epidermal growth factor and other polypeptide mitogens
    • Carpenter, G. (1987). Receptors for epidermal growth factor and other polypeptide mitogens. Annu. Rev. Biochem. 56, 881-914.
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 881-914
    • Carpenter, G.1
  • 6
    • 0028176477 scopus 로고
    • A neu acquaintance for erbB3 and erbB4: A role for receptor heterodimerization in growth signaling
    • Carraway, K.L., III, and Cantley, L.C. (1994). A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling. Cell 78, 5-8.
    • (1994) Cell , vol.78 , pp. 5-8
    • Carraway K.L. III1    Cantley, L.C.2
  • 7
    • 0027203952 scopus 로고
    • Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors
    • Chang, C.P., Lazar, C.S., Walsh, B.J., Komuro, M., Collawn, J.F., Kuhn, L.A., Tainer, J.A., Trowbridge, I.S., Farquhar, M.G., and Rosenfeld, M.G. (1993). Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. J. Biol. Chem. 268, 19312-19320.
    • (1993) J. Biol. Chem. , vol.268 , pp. 19312-19320
    • Chang, C.P.1    Lazar, C.S.2    Walsh, B.J.3    Komuro, M.4    Collawn, J.F.5    Kuhn, L.A.6    Tainer, J.A.7    Trowbridge, I.S.8    Farquhar, M.G.9    Rosenfeld, M.G.10
  • 8
    • 0024417285 scopus 로고
    • Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation
    • Chen, W.S., Lazar, C.S., Lund, K.A., Welsh, J.B., Chang, C.P., Walton, G.M., Der, C.J., Wiley, H.S., Gill, G.N., and Rosenfeld, M.G. (1989). Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell 59, 33-43.
    • (1989) Cell , vol.59 , pp. 33-43
    • Chen, W.S.1    Lazar, C.S.2    Lund, K.A.3    Welsh, J.B.4    Chang, C.P.5    Walton, G.M.6    Der, C.J.7    Wiley, H.S.8    Gill, G.N.9    Rosenfeld, M.G.10
  • 9
    • 0023238874 scopus 로고
    • Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor
    • Chen, W.S., Lazar, C.S., Poenie, M., Tsien, R.Y., Gill, G.N., and Rosenfeld, M.G. (1987). Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor. Nature 328, 820-823.
    • (1987) Nature , vol.328 , pp. 820-823
    • Chen, W.S.1    Lazar, C.S.2    Poenie, M.3    Tsien, R.Y.4    Gill, G.N.5    Rosenfeld, M.G.6
  • 11
    • 0026586256 scopus 로고
    • Epidermal growth factor (EGF)-stimulated tyrosine phosphorylation and EGF receptor degradation in cells expressing EGF receptors truncated at residue 973
    • Decker, S.J., Alexander, C., and Habib, T. (1992). Epidermal growth factor (EGF)-stimulated tyrosine phosphorylation and EGF receptor degradation in cells expressing EGF receptors truncated at residue 973. J. Biol. Chem. 267, 1104-1108.
    • (1992) J. Biol. Chem. , vol.267 , pp. 1104-1108
    • Decker, S.J.1    Alexander, C.2    Habib, T.3
  • 13
    • 0027965262 scopus 로고
    • Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma
    • Di Guglielmo, G.M., Baass, P.C., Ou, W.J., Posner, B.I., and Bergeron, J.J. (1994). Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma. EMBO J. 13, 4269-4277.
    • (1994) EMBO J. , vol.13 , pp. 4269-4277
    • Di Guglielmo, G.M.1    Baass, P.C.2    Ou, W.J.3    Posner, B.I.4    Bergeron, J.J.5
  • 14
    • 0022102126 scopus 로고
    • Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies
    • Drebin, J.A., Link, V.C., Stern, D.F., Weinberg, R.A., and Greene, M.I. (1985). Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies. Cell 41, 697-706.
    • (1985) Cell , vol.41 , pp. 697-706
    • Drebin, J.A.1    Link, V.C.2    Stern, D.F.3    Weinberg, R.A.4    Greene, M.I.5
  • 15
    • 0026574126 scopus 로고
    • Kinetics of binding, endocytosis, and recycling of EGF receptor mutants
    • Felder, S., LaVin, J., Ullrich, A., and Schlessinger, J. (1992). Kinetics of binding, endocytosis, and recycling of EGF receptor mutants. J. Cell Biol. 117, 203-212.
    • (1992) J. Cell Biol. , vol.117 , pp. 203-212
    • Felder, S.1    LaVin, J.2    Ullrich, A.3    Schlessinger, J.4
  • 16
    • 0025359062 scopus 로고
    • Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body
    • Felder, S., Miller, K., Moehren, G., Ullrich, A., Schlessinger, J., and Hopkins, C.R. (1990). Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body. Cell 61, 623-634.
    • (1990) Cell , vol.61 , pp. 623-634
    • Felder, S.1    Miller, K.2    Moehren, G.3    Ullrich, A.4    Schlessinger, J.5    Hopkins, C.R.6
  • 17
    • 0028930124 scopus 로고
    • Roles for a cytoplasmic tyrosine and tyrosine kinase activity in the interactions of Neu receptors with coated pits
    • Gilboa, L., Ben-Levy, R., Yarden, Y., and Henis, Y.I. (1995). Roles for a cytoplasmic tyrosine and tyrosine kinase activity in the interactions of Neu receptors with coated pits. J. Biol. Chem. 270, 7061-7067.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7061-7067
    • Gilboa, L.1    Ben-Levy, R.2    Yarden, Y.3    Henis, Y.I.4
  • 18
    • 0023840804 scopus 로고
    • Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivarion and by microinjection of anti-phosphotyrosine antibodies
    • Glenney, J.R., Jr., Chen, W.S., Lazar, C.S., Walton, G.M., Zokas, L.M., Rosenfeld, M.G., and Gill, G.N. (1988). Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivarion and by microinjection of anti-phosphotyrosine antibodies. Cell 52, 675-684.
    • (1988) Cell , vol.52 , pp. 675-684
    • Glenney J.R., Jr.1    Chen, W.S.2    Lazar, C.S.3    Walton, G.M.4    Zokas, L.M.5    Rosenfeld, M.G.6    Gill, G.N.7
  • 19
    • 0025690737 scopus 로고
    • Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: A mechanism for receptor transregulation
    • Goldman, R., Levy, R.B., Peles, E., and Yarden, Y. (1990). Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation. Biochemistry 29, 11024-11028.
    • (1990) Biochemistry , vol.29 , pp. 11024-11028
    • Goldman, R.1    Levy, R.B.2    Peles, E.3    Yarden, Y.4
  • 20
    • 0030944455 scopus 로고    scopus 로고
    • ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
    • Graus-Porta, D., Beerli, R.R., Daly, J.M., and Hynes, N.B. (1997). ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J. 16, 1647-1655.
    • (1997) EMBO J. , vol.16 , pp. 1647-1655
    • Graus-Porta, D.1    Beerli, R.R.2    Daly, J.M.3    Hynes, N.B.4
  • 21
    • 0028893444 scopus 로고
    • Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling
    • Graus-Porta, D., Beerli, R.R., and Hynes, N.E. (1995). Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling. Mol. Cell. Biol. 15, 1182-1191.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1182-1191
    • Graus-Porta, D.1    Beerli, R.R.2    Hynes, N.E.3
  • 22
    • 0028838012 scopus 로고
    • Dimerization of cell surface receptors in signal transduction
    • Heldin, C.H. (1995). Dimerization of cell surface receptors in signal transduction. Cell 80, 213-223.
    • (1995) Cell , vol.80 , pp. 213-223
    • Heldin, C.H.1
  • 23
    • 0025777103 scopus 로고
    • Internalization and down-regulation of the human epidermal growth factor receptor are regulated by the carboxyl-terminal tyrosines
    • Helin, K., and Beguinot, L. (1991). Internalization and down-regulation of the human epidermal growth factor receptor are regulated by the carboxyl-terminal tyrosines. J. Biol. Chem. 266, 8363-8368.
    • (1991) J. Biol. Chem. , vol.266 , pp. 8363-8368
    • Helin, K.1    Beguinot, L.2
  • 24
    • 0025370578 scopus 로고
    • Separate endocytic pathways of kinase-defective and -active EGF receptor mutants expressed in same cells
    • Honegger, A.M., Schmidt, A., Ullrich, A., and Schlessinger, J. (1990). Separate endocytic pathways of kinase-defective and -active EGF receptor mutants expressed in same cells. J. Cell Biol. 110, 1541-1548.
    • (1990) J. Cell Biol. , vol.110 , pp. 1541-1548
    • Honegger, A.M.1    Schmidt, A.2    Ullrich, A.3    Schlessinger, J.4
  • 25
    • 0023461796 scopus 로고
    • A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis
    • Honegger, A.M., Szapary, D., Schmidt, A., Lyall, R., Van Obberghen, E., Dull, T.J., Ullrich, A., and Schlessinger, J. (1987). A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis. Mol. Cell. Biol. 7, 4568-4571.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 4568-4571
    • Honegger, A.M.1    Szapary, D.2    Schmidt, A.3    Lyall, R.4    Van Obberghen, E.5    Dull, T.J.6    Ullrich, A.7    Schlessinger, J.8
  • 26
    • 0023430930 scopus 로고
    • Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells
    • Hudziak, R.M., Schlessinger, J., and Ullrich, A. (1987). Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells. Proc. Natl. Acad. Sci. USA 84, 7159-7163.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7159-7163
    • Hudziak, R.M.1    Schlessinger, J.2    Ullrich, A.3
  • 27
    • 0028912598 scopus 로고
    • Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake
    • Hurwitz, E., Stancovski, I., Sela, M., and Yarden, Y. (1995). Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake. Proc. Natl. Acad. Sci. USA 92, 3353-3357.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3353-3357
    • Hurwitz, E.1    Stancovski, I.2    Sela, M.3    Yarden, Y.4
  • 29
    • 0030959114 scopus 로고    scopus 로고
    • A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks cross-talk with growth factor receptors
    • Klapper, L.N., Vaisman, N., Hurwitz, E., Pinkas-Kramarski, R., Yarden, Y., and Sela, M. (1997). A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks cross-talk with growth factor receptors. Oncogene 14, 2099-2109.
    • (1997) Oncogene , vol.14 , pp. 2099-2109
    • Klapper, L.N.1    Vaisman, N.2    Hurwitz, E.3    Pinkas-Kramarski, R.4    Yarden, Y.5    Sela, M.6
  • 30
    • 0025765803 scopus 로고
    • SH2 and SH3 domains: Elements that control interactions of cytoplasmic signaling proteins
    • Koch, C.A., Anderson, D., Moran, M.F., Ellis, C., and Pawson, T. (1991). SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science 252, 668-674.
    • (1991) Science , vol.252 , pp. 668-674
    • Koch, C.A.1    Anderson, D.2    Moran, M.F.3    Ellis, C.4    Pawson, T.5
  • 31
    • 0024326947 scopus 로고
    • Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors
    • Kraus, M.H., Issing, W., Miki, T., Popescu, N.C., and Aaronson, S.A. (1989). Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc. Natl. Acad. Sci. USA 86, 9193-9197.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9193-9197
    • Kraus, M.H.1    Issing, W.2    Miki, T.3    Popescu, N.C.4    Aaronson, S.A.5
  • 32
    • 0023301170 scopus 로고
    • Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms
    • Kraus, M.H., Popescu, N.C., Amsbaugh, S.C., and King, C.R. (1987). Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms. EMBO J. 6, 605-610.
    • (1987) EMBO J. , vol.6 , pp. 605-610
    • Kraus, M.H.1    Popescu, N.C.2    Amsbaugh, S.C.3    King, C.R.4
  • 33
    • 0029032117 scopus 로고
    • Regulation of Her2/neu gene expression
    • Miller, S.A., and Hung, M.-C. (1995). Regulation of Her2/neu gene expression (review). Oncol. Rep. 2, 497-503.
    • (1995) Oncol. Rep. , vol.2 , pp. 497-503
    • Miller, S.A.1    Hung, M.-C.2
  • 35
    • 0028859279 scopus 로고
    • Protein modules and signaling networks
    • Pawson, T. (1995). Protein modules and signaling networks. Nature 373, 573-580.
    • (1995) Nature , vol.373 , pp. 573-580
    • Pawson, T.1
  • 36
    • 0027720285 scopus 로고
    • Neu and its ligands: From an oncogene to neural factors
    • Peles, E., and Yarden, Y. (1993). Neu and its ligands: from an oncogene to neural factors. Bioessays 15, 815-824.
    • (1993) Bioessays , vol.15 , pp. 815-824
    • Peles, E.1    Yarden, Y.2
  • 38
    • 2142843806 scopus 로고    scopus 로고
    • Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
    • Pinkas-Kramarski, R., et al. (1996). Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J. 15, 2452-2467.
    • (1996) EMBO J. , vol.15 , pp. 2452-2467
    • Pinkas-Kramarski, R.1
  • 40
    • 0028156927 scopus 로고
    • Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: A mechanism of interreceptor kinase activation and transphosphorylation
    • Qian, X., LeVea, C.M., Freeman, J.K., Dougall, W.C., and Greene, M.I. (1994). Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation. Proc. Natl. Acad. Sci. USA 91, 1500-1504.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1500-1504
    • Qian, X.1    LeVea, C.M.2    Freeman, J.K.3    Dougall, W.C.4    Greene, M.I.5
  • 41
    • 0031034106 scopus 로고    scopus 로고
    • HER-2/neu signal transduction in human breast and ovarian cancer
    • Reese, D.M., and Slamon, D.J. (1997). HER-2/neu signal transduction in human breast and ovarian cancer. Stem Cells 15, 1-8.
    • (1997) Stem Cells , vol.15 , pp. 1-8
    • Reese, D.M.1    Slamon, D.J.2
  • 42
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger, J., and Ullrich, A. (1992). Growth factor signaling by receptor tyrosine kinases. Neuron 9, 383-391.
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ullrich, A.2
  • 43
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon, D.J., Clark, G.M., Wong, S.G., Levin, W.J., Ullrich, A., and McGuire, W.L. (1987). Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235, 177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 46
    • 0028302018 scopus 로고
    • ErbB3is involved inactivationofphosphatidylinositol 3-kinase by epidermal growth factor
    • Soltoff, S.P., Carraway, K.L., III, Prigent, S.A., Gullick, W.G., and Cantley, L.C. (1994). ErbB3is involved inactivationofphosphatidylinositol 3-kinase by epidermal growth factor. Mol. Cell. Biol. 14, 3550-3558.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3550-3558
    • Soltoff, S.P.1    Carraway K.L. III2    Prigent, S.A.3    Gullick, W.G.4    Cantley, L.C.5
  • 47
    • 0027382449 scopus 로고
    • The carboxyl terminus of epidermal growth factor receptor/erbB-2 chimerae is internalization impaired
    • Sorkin, A., Di Fiore, P.P., and Carpenter, G. (1993). The carboxyl terminus of epidermal growth factor receptor/erbB-2 chimerae is internalization impaired. Oncogene 8, 3021-3028.
    • (1993) Oncogene , vol.8 , pp. 3021-3028
    • Sorkin, A.1    Di Fiore, P.P.2    Carpenter, G.3
  • 48
    • 0026687216 scopus 로고
    • Multiple autophosphorylation sites of the epidermal growth factor receptor are essential for receptor kinase activity and internalization. Contrasting significance of tyrosine 992 in the native and truncated receptors
    • Sorkin, A., Helin, K., Waters, C.M., Carpenter, G., and Beguinot, L. (1992). Multiple autophosphorylation sites of the epidermal growth factor receptor are essential for receptor kinase activity and internalization. Contrasting significance of tyrosine 992 in the native and truncated receptors. J. Biol. Chem. 267, 8672-8678.
    • (1992) J. Biol. Chem. , vol.267 , pp. 8672-8678
    • Sorkin, A.1    Helin, K.2    Waters, C.M.3    Carpenter, G.4    Beguinot, L.5
  • 49
    • 0025830686 scopus 로고
    • Multiple autophosphorylation site mutations of the epidermal growth factor receptor. Analysis of kinase activity and endocytosis
    • Sorkin, A., Waters, C., Overholser, K.A., and Carpenter, G. (1991). Multiple autophosphorylation site mutations of the epidermal growth factor receptor. Analysis of kinase activity and endocytosis. J. Biol. Chem. 266, 8355-8362.
    • (1991) J. Biol. Chem. , vol.266 , pp. 8355-8362
    • Sorkin, A.1    Waters, C.2    Overholser, K.A.3    Carpenter, G.4
  • 50
    • 0026700010 scopus 로고
    • Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses
    • Spivak-Kroizman, T., Rotin, D., Pinchasi, D., Ullrich, A., Schlessinger, J., and Lax, I. (1992). Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses. J. Biol. Chem. 267, 8056-8063.
    • (1992) J. Biol. Chem. , vol.267 , pp. 8056-8063
    • Spivak-Kroizman, T.1    Rotin, D.2    Pinchasi, D.3    Ullrich, A.4    Schlessinger, J.5    Lax, I.6
  • 51
    • 0023822220 scopus 로고
    • Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivo
    • Stern, D.F., Kamps, M.P., and Cao, H. (1988). Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivo. Mol. Cell. Biol. 8, 3969-3973.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3969-3973
    • Stern, D.F.1    Kamps, M.P.2    Cao, H.3
  • 52
    • 0029814271 scopus 로고    scopus 로고
    • A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
    • Tzahar, E., Waterman, H., Chen, X., Levkowitz, G., Karunagaran, D., Lavi, S., Ratzkin, B.J., and Yarden, Y. (1996). A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol. Cell. Biol. 16, 5276-5287.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5276-5287
    • Tzahar, E.1    Waterman, H.2    Chen, X.3    Levkowitz, G.4    Karunagaran, D.5    Lavi, S.6    Ratzkin, B.J.7    Yarden, Y.8
  • 53
    • 0021273420 scopus 로고
    • Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
    • Ullrich, A., Coussens, L., Hayflick, J.S., Dull, T.J., Gray, A., Tam, A.W., Lee, J., Yarden, Y., Libermann, T.A., and Schlessinger, J. (1984). Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 309, 418-425.
    • (1984) Nature , vol.309 , pp. 418-425
    • Ullrich, A.1    Coussens, L.2    Hayflick, J.S.3    Dull, T.J.4    Gray, A.5    Tam, A.W.6    Lee, J.7    Yarden, Y.8    Libermann, T.A.9    Schlessinger, J.10
  • 54
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich, A., and Schlessinger, J. (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 55
    • 0030461226 scopus 로고    scopus 로고
    • Control of EGF receptor signaling by clathrin-mediated endocytosis
    • Vieira, A.V., Lamaze, C., and Schmid, S.L. (1996). Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274, 2086-2089.
    • (1996) Science , vol.274 , pp. 2086-2089
    • Vieira, A.V.1    Lamaze, C.2    Schmid, S.L.3
  • 56
    • 0025194462 scopus 로고
    • Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function
    • Wada, T., Qian, X.L., and Greene, M.I. (1990). Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function. Cell 61, 1339-1347.
    • (1990) Cell , vol.61 , pp. 1339-1347
    • Wada, T.1    Qian, X.L.2    Greene, M.I.3
  • 57
    • 2642593022 scopus 로고    scopus 로고
    • Requirement for phospholipase C-gammal enzymatic activity in growth factor-induced mitogenesis
    • Wang, Z., Gluck, S., Zhang, L., and Moran, M. (1998). Requirement for Phospholipase C-gammal enzymatic activity in growth factor-induced mitogenesis. Mol. Cell. Biol. 18, 590-597.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 590-597
    • Wang, Z.1    Gluck, S.2    Zhang, L.3    Moran, M.4
  • 58
    • 0030036079 scopus 로고    scopus 로고
    • Requirement for the adapter protein GRB2 in EGF receptor endocytosis
    • Wang, Z., and Moran, M.F. (1996). Requirement for the adapter protein GRB2 in EGF receptor endocytosis. Science 272, 1935-1939.
    • (1996) Science , vol.272 , pp. 1935-1939
    • Wang, Z.1    Moran, M.F.2
  • 59
    • 0030033689 scopus 로고    scopus 로고
    • Association of p120 ras GAP with endocytic components and colocalization with epidermal growth factor (EGF) receptor in response to EGF stimulation
    • Wang, Z., Tung, P.S., and Moran, M.F. (1996). Association of p120 ras GAP with endocytic components and colocalization with epidermal growth factor (EGF) receptor in response to EGF stimulation. Cell Growth & Differ. 7, 123-133.
    • (1996) Cell Growth & Differ. , vol.7 , pp. 123-133
    • Wang, Z.1    Tung, P.S.2    Moran, M.F.3
  • 60
    • 0024505028 scopus 로고
    • A point mutation in the neu oncogene mimics ligand induction of receptor aggregation
    • Weiner, D.B., Liu, J., Cohen, J.A., Williams, W.V., and Greene, M.I. (1989). A point mutation in the neu oncogene mimics ligand induction of receptor aggregation. Nature 339, 230-231.
    • (1989) Nature , vol.339 , pp. 230-231
    • Weiner, D.B.1    Liu, J.2    Cohen, J.A.3    Williams, W.V.4    Greene, M.I.5
  • 61
    • 0025139326 scopus 로고
    • Ligand-induced transformation by a noninternalizing epidermal growth factor receptor
    • Wells, A., Welsh, J.B., Lazar, C.S., Wiley, H.S., Gill, G.N., and Rosenfeld, M.G. (1990). Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science 247, 962-964.
    • (1990) Science , vol.247 , pp. 962-964
    • Wells, A.1    Welsh, J.B.2    Lazar, C.S.3    Wiley, H.S.4    Gill, G.N.5    Rosenfeld, M.G.6
  • 62
    • 0025908557 scopus 로고
    • The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor
    • Wiley, H.S., Herbst, J.J., Walsh, B.J., Lauffenburger, D.A., Rosenfeld, M.G., and Gill, G.N. (1991). The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor. J. Biol. Chem. 266, 11083-11094.
    • (1991) J. Biol. Chem. , vol.266 , pp. 11083-11094
    • Wiley, H.S.1    Herbst, J.J.2    Walsh, B.J.3    Lauffenburger, D.A.4    Rosenfeld, M.G.5    Gill, G.N.6
  • 63
    • 0030968648 scopus 로고    scopus 로고
    • Structural aspects of the epidermal growth factor receptor required for transmodulation of erbB2/neu
    • Worthylake, R., and Wiley, H.S. (1997). Structural aspects of the epidermal growth factor receptor required for transmodulation of erbB2/neu. J. Biol. Chem. 272, 8594-8601.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8594-8601
    • Worthylake, R.1    Wiley, H.S.2
  • 64
    • 0022588467 scopus 로고
    • Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor
    • Yamamoto, T., Ikawa, S., Akiyama, T., Nomura, N., Miyajima, N., Saito, T., and Toyoshima, K. (1986). Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor. Nature 319, 230-234.
    • (1986) Nature , vol.319 , pp. 230-234
    • Yamamoto, T.1    Ikawa, S.2    Akiyama, T.3    Nomura, N.4    Miyajima, N.5    Saito, T.6    Toyoshima, K.7
  • 65
    • 0023156382 scopus 로고
    • Self-phosphorylation of epidermal growth factor receptor: Evidence for a model of intermolecular allosteric activation
    • Yarden, Y., and Schlessinger, J. (1987). Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation. Biochemistry 26, 1434-1442.
    • (1987) Biochemistry , vol.26 , pp. 1434-1442
    • Yarden, Y.1    Schlessinger, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.