메뉴 건너뛰기




Volumn 5, Issue 10, 2010, Pages

P130Cas Src-binding and substrate domains have distinct roles in sustaining focal adhesion disassembly and promoting cell migration

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CRK ASSOCIATED SUBSTRATE PROTEIN; PROTEIN SH3; PROTEIN TYROSINE KINASE; TYROSINE;

EID: 78149441694     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013412     Document Type: Article
Times cited : (46)

References (40)
  • 1
    • 3142763039 scopus 로고    scopus 로고
    • Actin and microtubules in cell motility: Which one is in control?
    • Etienne-Manneville S (2004) Actin and microtubules in cell motility: which one is in control? Traffic 5: 470-477.
    • (2004) Traffic , vol.5 , pp. 470-477
    • Etienne-Manneville, S.1
  • 2
    • 42049092972 scopus 로고    scopus 로고
    • Regulation of actin assembly associated with protrusion and adhesion in cell migration
    • Le Clainche C, Carlier MF (2008) Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol Rev 88: 489-513.
    • (2008) Physiol Rev , vol.88 , pp. 489-513
    • Le Clainche, C.1    Carlier, M.F.2
  • 4
    • 0036222549 scopus 로고    scopus 로고
    • Sensing the environment: A historical perspective on integrin signal transduction
    • Miranti CK, Brugge JS (2002) Sensing the environment: a historical perspective on integrin signal transduction. Nat Cell Biol 4: E83-E90.
    • (2002) Nat Cell Biol , vol.4
    • Miranti, C.K.1    Brugge, J.S.2
  • 6
    • 3042717667 scopus 로고    scopus 로고
    • Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold
    • Chodniewicz D, Klemke RL (2004) Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold. Biochim Biophys Acta-Mol Cell Res 1692: 63-76.
    • (2004) Biochim Biophys Acta-Mol Cell Res , vol.1692 , pp. 63-76
    • Chodniewicz, D.1    Klemke, R.L.2
  • 7
    • 0035474419 scopus 로고    scopus 로고
    • Functions of the adapter protein Cas: Signal convergence and the determination of cellular responses
    • Bouton AH, Riggins RB, Bruce-Staskal PJ (2001) Functions of the adapter protein Cas: signal convergence and the determination of cellular responses. Oncogene 20: 6448-6458.
    • (2001) Oncogene , vol.20 , pp. 6448-6458
    • Bouton, A.H.1    Riggins, R.B.2    Bruce-Staskal, P.J.3
  • 8
    • 33646557326 scopus 로고    scopus 로고
    • P130Cas: A versatile scaffold in signaling networks
    • Defilippi P, Di Stefano P, Cabodi S (2006) p130Cas: a versatile scaffold in signaling networks. Trends Cell Biol 16: 257-263.
    • (2006) Trends Cell Biol , vol.16 , pp. 257-263
    • Defilippi, P.1    Di Stefano, P.2    Cabodi, S.3
  • 9
    • 0034160011 scopus 로고    scopus 로고
    • Integrin signalling: A new Cas(t) of characters enters the stage
    • O'Neill GM, Fashena SJ, Golemis EA (2000) Integrin signalling: a new Cas(t) of characters enters the stage. Trends Cell Biol 10: 111-119.
    • (2000) Trends Cell Biol , vol.10 , pp. 111-119
    • O'Neill, G.M.1    Fashena, S.J.2    Golemis, E.A.3
  • 10
    • 0027990414 scopus 로고
    • A Novel Signaling Molecule, P130, Forms Stable Complexes in-Vivo with V-Crk and VSrc in a Tyrosine Phosphorylation-Dependent Manner
    • Sakai R, Iwamatsu A, Hirano N, Ogawa S, Tanaka T, et al. (1994) A Novel Signaling Molecule, P130, Forms Stable Complexes in-Vivo with V-Crk and VSrc in a Tyrosine Phosphorylation-Dependent Manner. EMBO J 13: 3748-3756.
    • (1994) EMBO J , vol.13 , pp. 3748-3756
    • Sakai, R.1    Iwamatsu, A.2    Hirano, N.3    Ogawa, S.4    Tanaka, T.5
  • 11
    • 17344362766 scopus 로고    scopus 로고
    • Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130(Cas)
    • Honda H, Oda H, Nakamoto T, Honda Z, Sakai R, et al. (1998) Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130(Cas). Nat Gen 19: 361-365.
    • (1998) Nat Gen , vol.19 , pp. 361-365
    • Honda, H.1    Oda, H.2    Nakamoto, T.3    Honda, Z.4    Sakai, R.5
  • 13
    • 0037128213 scopus 로고    scopus 로고
    • Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold
    • Cho SY, Klemke RL (2002) Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold. J Cell Biol 156: 725-736.
    • (2002) J Cell Biol , vol.156 , pp. 725-736
    • Cho, S.Y.1    Klemke, R.L.2
  • 14
    • 0032559562 scopus 로고    scopus 로고
    • CAS/Crk coupling serves as a ''molecular switch'' for induction of cell migration
    • Klemke RL, Leng J, Molander R, Brooks PC, Vuori K, et al. (1998) CAS/Crk coupling serves as a ''molecular switch'' for induction of cell migration. J Cell Biol 140: 961-972.
    • (1998) J Cell Biol , vol.140 , pp. 961-972
    • Klemke, R.L.1    Leng, J.2    Molander, R.3    Brooks, P.C.4    Vuori, K.5
  • 15
    • 4644305806 scopus 로고    scopus 로고
    • Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration
    • Shin NY, Dise RS, Schneider-Mergener J, Ritchie MD, Kilkenny DM, et al. (2004) Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration. J Biol Chem 279: 38331-38337.
    • (2004) J Biol Chem , vol.279 , pp. 38331-38337
    • Shin, N.Y.1    Dise, R.S.2    Schneider-Mergener, J.3    Ritchie, M.D.4    Kilkenny, D.M.5
  • 17
    • 0034769929 scopus 로고    scopus 로고
    • Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src
    • Ruest PJ, Shin NY, Polte TR, Zhang X, Hanks SK (2001) Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src. Mol Cell Biol 21: 7641-7652.
    • (2001) Mol Cell Biol , vol.21 , pp. 7641-7652
    • Ruest, P.J.1    Shin, N.Y.2    Polte, T.R.3    Zhang, X.4    Hanks, S.K.5
  • 18
    • 0029945648 scopus 로고    scopus 로고
    • Direct binding of Cterminal region of p130Cas to SH2 and SH3 domains of Src kinase
    • Nakamoto T, Sakai R, Ozawa K, Yazaki Y, Hirai H (1996) Direct binding of Cterminal region of p130Cas to SH2 and SH3 domains of Src kinase. J Biol Chem 271: 8959-8965.
    • (1996) J Biol Chem , vol.271 , pp. 8959-8965
    • Nakamoto, T.1    Sakai, R.2    Ozawa, K.3    Yazaki, Y.4    Hirai, H.5
  • 19
    • 1642575210 scopus 로고    scopus 로고
    • Regulation and localization of CAS substrate domain tyrosine phosphorylation
    • Fonseca PM, Shin NY, Brabek J, Ryzhova L, Wu J, et al. (2004) Regulation and localization of CAS substrate domain tyrosine phosphorylation. Cell Signalling 16: 621-629.
    • (2004) Cell Signalling , vol.16 , pp. 621-629
    • Fonseca, P.M.1    Shin, N.Y.2    Brabek, J.3    Ryzhova, L.4    Wu, J.5
  • 20
    • 21344443681 scopus 로고    scopus 로고
    • Crkassociated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells
    • Brabek J, Constancio SS, Siesser PF, Shin NY, Pozzi A, et al. (2005) Crkassociated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells. Mol Cancer Res 3: 307-315.
    • (2005) Mol Cancer Res , vol.3 , pp. 307-315
    • Brabek, J.1    Constancio, S.S.2    Siesser, P.F.3    Shin, N.Y.4    Pozzi, A.5
  • 21
    • 33751335857 scopus 로고    scopus 로고
    • Force sensing by mechanical extension of the Src family kinase substrate p130Cas
    • Sawada Y, Tamada M, Dubin-Thaler BJ, Cherniavskaya O, Sakai R, et al. (2006) Force sensing by mechanical extension of the Src family kinase substrate p130Cas. Cell 127: 1015-1026.
    • (2006) Cell , vol.127 , pp. 1015-1026
    • Sawada, Y.1    Tamada, M.2    Dubin-Thaler, B.J.3    Cherniavskaya, O.4    Sakai, R.5
  • 22
    • 33645234372 scopus 로고    scopus 로고
    • Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer
    • Ballestrem C, Erez N, Kirchner J, Kam Z, Bershadsky A, et al. (2006) Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer. J Cell Sci 119: 866-875.
    • (2006) J Cell Sci , vol.119 , pp. 866-875
    • Ballestrem, C.1    Erez, N.2    Kirchner, J.3    Kam, Z.4    Bershadsky, A.5
  • 23
    • 84860292363 scopus 로고    scopus 로고
    • P130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptornegative breast cancer cells
    • Cunningham-Edmondson AC, Hanks SK (2009) P130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptornegative breast cancer cells. Breast Cancer: Targets and Therapy 1: 39-52.
    • (2009) Breast Cancer: Targets and Therapy , vol.1 , pp. 39-52
    • Cunningham-Edmondson, A.C.1    Hanks, S.K.2
  • 24
    • 33745447261 scopus 로고    scopus 로고
    • Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B
    • Rivera GM, Antoku S, Gelkop S, Shin NY, Hanks SK, et al. (2006) Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B. Proc Natl Acad Sci USA 103: 9536-9541.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 9536-9541
    • Rivera, G.M.1    Antoku, S.2    Gelkop, S.3    Shin, N.Y.4    Hanks, S.K.5
  • 25
    • 1642586962 scopus 로고    scopus 로고
    • FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly
    • Webb DJ, Donais K, Whitmore LA, Thomas SM, Turner CE, et al. (2004) FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nat Cell Biol 6: 154-161.
    • (2004) Nat Cell Biol , vol.6 , pp. 154-161
    • Webb, D.J.1    Donais, K.2    Whitmore, L.A.3    Thomas, S.M.4    Turner, C.E.5
  • 26
    • 0037178809 scopus 로고    scopus 로고
    • Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrate
    • Huang J, Hamasaki H, Nakamoto T, Honda H, Hirai H, et al. (2002) Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrate. J Biol Chem 277: 27265-27272.
    • (2002) J Biol Chem , vol.277 , pp. 27265-27272
    • Huang, J.1    Hamasaki, H.2    Nakamoto, T.3    Honda, H.4    Hirai, H.5
  • 27
    • 0034630157 scopus 로고    scopus 로고
    • Crkassociated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells
    • Donaldson JC, Dempsey PJ, Reddy S, Bouton AH, Coffey RJ, et al. (2000) Crkassociated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells. Exp Cell Res 256: 168-178.
    • (2000) Exp Cell Res , vol.256 , pp. 168-178
    • Donaldson, J.C.1    Dempsey, P.J.2    Reddy, S.3    Bouton, A.H.4    Coffey, R.J.5
  • 28
    • 0034640060 scopus 로고    scopus 로고
    • Association of p130CAS with phosphatidylinositol-3-OH kinase mediates adenovirus cell entry
    • Li E, Stupack DG, Brown SL, Klemke R, Schlaepfer DD, et al. (2000) Association of p130CAS with phosphatidylinositol-3-OH kinase mediates adenovirus cell entry. J Biol Chem 275: 14729-14735.
    • (2000) J Biol Chem , vol.275 , pp. 14729-14735
    • Li, E.1    Stupack, D.G.2    Brown, S.L.3    Klemke, R.4    Schlaepfer, D.D.5
  • 29
    • 33846176546 scopus 로고    scopus 로고
    • Probing the integrin-actin linkage using high-resolution protein velocity mapping
    • Brown CM, Hebert B, Kolin DL, Zareno J, Whitmore L, et al. (2006) Probing the integrin-actin linkage using high-resolution protein velocity mapping. J Cell Sci 119: 5204-5214.
    • (2006) J Cell Sci , vol.119 , pp. 5204-5214
    • Brown, C.M.1    Hebert, B.2    Kolin, D.L.3    Zareno, J.4    Whitmore, L.5
  • 30
  • 31
    • 34247856103 scopus 로고    scopus 로고
    • Flux at focal adhesions: Slippage clutch, mechanical gauge, or signal depot
    • Wang YL (2007) Flux at focal adhesions: slippage clutch, mechanical gauge, or signal depot. Sci STKE 2007: pe10.
    • (2007) Sci STKE
    • Wang, Y.L.1
  • 32
    • 37549017373 scopus 로고    scopus 로고
    • A FAK/Src chimera with gain-of-function properties promotes formation of large peripheral adhesions associated with dynamic actin assembly
    • Siesser PM, Meenderink LM, Ryzhova L, Michael KE, Dumbauld DW, et al. (2008) A FAK/Src chimera with gain-of-function properties promotes formation of large peripheral adhesions associated with dynamic actin assembly. Cell Motil Cytoskeleton 65: 25-39.
    • (2008) Cell Motil Cytoskeleton , vol.65 , pp. 25-39
    • Siesser, P.M.1    Meenderink, L.M.2    Ryzhova, L.3    Michael, K.E.4    Dumbauld, D.W.5
  • 33
    • 22744434624 scopus 로고    scopus 로고
    • Cortactin promotes cell motility by enhancing lamellipodial persistence
    • Bryce NS, Clark ES, Leysath JL, Currie JD, Webb DJ, et al. (2005) Cortactin promotes cell motility by enhancing lamellipodial persistence. Curr Biol 15: 1276-1285.
    • (2005) Curr Biol , vol.15 , pp. 1276-1285
    • Bryce, N.S.1    Clark, E.S.2    Leysath, J.L.3    Currie, J.D.4    Webb, D.J.5
  • 34
    • 57349100453 scopus 로고    scopus 로고
    • Distinct phosphoforms of cortactin differentially regulate actin polymerization and focal adhesions
    • Kruchten AE, Krueger EW, Wang Y, McNiven MA (2008) Distinct phosphoforms of cortactin differentially regulate actin polymerization and focal adhesions. Am J Physiol Cell Physiol 295: C1113-C1122.
    • (2008) Am J Physiol Cell Physiol , vol.295
    • Kruchten, A.E.1    Krueger, E.W.2    Wang, Y.3    McNiven, M.A.4
  • 35
    • 33846781373 scopus 로고    scopus 로고
    • A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions
    • Zaidel-Bar R, Milo R, Kam Z, Geiger B (2007) A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions. J Cell Sci 120: 137-148.
    • (2007) J Cell Sci , vol.120 , pp. 137-148
    • Zaidel-Bar, R.1    Milo, R.2    Kam, Z.3    Geiger, B.4
  • 38
    • 38949116282 scopus 로고    scopus 로고
    • Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites
    • Efimov A, Schiefermeier N, Grigoriev I, Ohi R, Brown MC, et al. (2008) Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites. J Cell Sci 121: 196-204.
    • (2008) J Cell Sci , vol.121 , pp. 196-204
    • Efimov, A.1    Schiefermeier, N.2    Grigoriev, I.3    Ohi, R.4    Brown, M.C.5
  • 39
    • 0022390903 scopus 로고
    • Exchange of actin subunits at the leading edge of living fibroblasts: Possible role of treadmilling
    • Wang YL (1985) Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmilling. J Cell Biol 101: 597-602.
    • (1985) J Cell Biol , vol.101 , pp. 597-602
    • Wang, Y.L.1
  • 40
    • 41949088527 scopus 로고    scopus 로고
    • Arp2/3 complex interactions and actin network turnover in lamellipodia
    • Lai FP, Szczodrak M, Block J, Faix J, Breitsprecher D, et al. (2008) Arp2/3 complex interactions and actin network turnover in lamellipodia. EMBO J 27: 982-992.
    • (2008) EMBO J , vol.27 , pp. 982-992
    • Lai, F.P.1    Szczodrak, M.2    Block, J.3    Faix, J.4    Breitsprecher, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.