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Volumn 186, Issue 10, 2011, Pages 5638-5647

Noncanonical K27-linked polyubiquitination of TIEG1 regulates Foxp3 expression and tumor growth

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; KRUPPEL LIKE FACTOR; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR TIEG1; TRANSFORMING GROWTH FACTOR BETA; TYROSINE; UNCLASSIFIED DRUG;

EID: 79956194738     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003801     Document Type: Article
Times cited : (37)

References (66)
  • 1
    • 34547749066 scopus 로고    scopus 로고
    • Emerging challenges in regulatory T cell function and biology
    • DOI 10.1126/science.1142331
    • Sakaguchi, S., and F. Powrie. 2007. Emerging challenges in regulatory T cell function and biology. Science 317: 627-629. (Pubitemid 47229955)
    • (2007) Science , vol.317 , Issue.5838 , pp. 627-629
    • Sakaguchi, S.1    Powrie, F.2
  • 2
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+ CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • Chen, W., W. Jin, N. Hardegen, K. J. Lei, L. Li, N. Marinos, G. McGrady, and S. M. Wahl. 2003. Conversion of peripheral CD4+CD25- naive T cells to CD4+ CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 198: 1875-1886.
    • (2003) J. Exp. Med. , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 3
    • 48449086316 scopus 로고    scopus 로고
    • TGF-beta: A master of all T cell trades
    • Li, M. O., and R. A. Flavell. 2008. TGF-beta: a master of all T cell trades. Cell 134: 392-404.
    • (2008) Cell , vol.134 , pp. 392-404
    • Li, M.O.1    Flavell, R.A.2
  • 6
    • 33847337912 scopus 로고    scopus 로고
    • Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: Role of tumor-derived TGF-beta
    • Liu, V. C., L. Y. Wong, T. Jang, A. H. Shah, I. Park, X. Yang, Q. Zhang, S. Lonning, B. A. Teicher, and C. Lee. 2007. Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta. J. Immunol. 178: 2883-2892.
    • (2007) J. Immunol. , vol.178 , pp. 2883-2892
    • Liu, V.C.1    Wong, L.Y.2    Jang, T.3    Shah, A.H.4    Park, I.5    Yang, X.6    Zhang, Q.7    Lonning, S.8    Teicher, B.A.9    Lee, C.10
  • 8
    • 0033820365 scopus 로고    scopus 로고
    • TGF-beta-based immunotherapy for cancer: Breaching the tumor firewall
    • Shah, A. H., and C. Lee. 2000. TGF-beta-based immunotherapy for cancer: breaching the tumor firewall. Prostate 45: 167-172.
    • (2000) Prostate , vol.45 , pp. 167-172
    • Shah, A.H.1    Lee, C.2
  • 9
    • 0035689762 scopus 로고    scopus 로고
    • Malignant cells, directors of the malignant process: Role of transforming growth factor-beta
    • DOI 10.1023/A:1013177011767
    • Teicher, B. A. 2001. Malignant cells, directors of the malignant process: role of transforming growth factor-beta. Cancer Metastasis Rev. 20: 133-143. (Pubitemid 34074689)
    • (2001) Cancer and Metastasis Reviews , vol.20 , Issue.1-2 , pp. 133-143
    • Teicher, B.A.1
  • 10
    • 47549090432 scopus 로고    scopus 로고
    • TGFbeta in Cancer
    • Massagué, J. 2008. TGFbeta in Cancer. Cell 134: 215-230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massagué, J.1
  • 11
    • 35548950221 scopus 로고    scopus 로고
    • Regulatory-T-cell inhibition versus depletion: The right choice in cancer immunotherapy
    • Colombo, M. P., and S. Piconese. 2007. Regulatory-T-cell inhibition versus depletion: the right choice in cancer immunotherapy. Nat. Rev. Cancer 7: 880-887.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 880-887
    • Colombo, M.P.1    Piconese, S.2
  • 12
    • 33646239606 scopus 로고    scopus 로고
    • Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent
    • Valzasina, B., S. Piconese, C. Guiducci, and M. P. Colombo. 2006. Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent. Cancer Res. 66: 4488-4495.
    • (2006) Cancer Res. , vol.66 , pp. 4488-4495
    • Valzasina, B.1    Piconese, S.2    Guiducci, C.3    Colombo, M.P.4
  • 13
    • 34948875291 scopus 로고    scopus 로고
    • CD70+ non-Hodgkin lymphoma B cells induce Foxp3 expression and regulatory function in intratumoral CD4+CD25 T cells
    • Yang, Z. Z., A. J. Novak, S. C. Ziesmer, T. E. Witzig, and S. M. Ansell. 2007. CD70+ non-Hodgkin lymphoma B cells induce Foxp3 expression and regulatory function in intratumoral CD4+CD25 T cells. Blood 110: 2537-2544.
    • (2007) Blood , vol.110 , pp. 2537-2544
    • Yang, Z.Z.1    Novak, A.J.2    Ziesmer, S.C.3    Witzig, T.E.4    Ansell, S.M.5
  • 14
    • 65549112641 scopus 로고    scopus 로고
    • Dynamic behavior and function of Foxp3+ regulatory T cells in tumor bearing host
    • Qin, F. X. 2009. Dynamic behavior and function of Foxp3+ regulatory T cells in tumor bearing host. Cell. Mol. Immunol. 6: 3-13.
    • (2009) Cell. Mol. Immunol. , vol.6 , pp. 3-13
    • Qin, F.X.1
  • 15
    • 77950349016 scopus 로고    scopus 로고
    • Th17 and regulatory T cells in mediating and restraining inflammation
    • Littman, D. R., and A. Y. Rudensky. 2010. Th17 and regulatory T cells in mediating and restraining inflammation. Cell 140: 845-858.
    • (2010) Cell , vol.140 , pp. 845-858
    • Littman, D.R.1    Rudensky, A.Y.2
  • 16
    • 42649115767 scopus 로고    scopus 로고
    • TH17 cells in development: An updated view of their molecular identity and genetic programming
    • Dong, C. 2008. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat. Rev. Immunol. 8: 337-348.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 337-348
    • Dong, C.1
  • 21
    • 39449083806 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1
    • Venuprasad, K., H. Huang, Y. Harada, C. Elly, M. Subramaniam, T. Spelsberg, J. Su, and Y. C. Liu. 2008. The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1. Nat. Immunol. 9: 245-253.
    • (2008) Nat. Immunol. , vol.9 , pp. 245-253
    • Venuprasad, K.1    Huang, H.2    Harada, Y.3    Elly, C.4    Subramaniam, M.5    Spelsberg, T.6    Su, J.7    Liu, Y.C.8
  • 22
    • 24044547036 scopus 로고    scopus 로고
    • Regulating the regulators: Control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli
    • DOI 10.1016/j.molcel.2005.08.017, PII S1097276505015595
    • Gao, M., and M. Karin. 2005. Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli. Mol. Cell 19: 581-593. (Pubitemid 41219435)
    • (2005) Molecular Cell , vol.19 , Issue.5 , pp. 581-593
    • Gao, M.1    Karin, M.2
  • 23
    • 77951034912 scopus 로고    scopus 로고
    • Cbl-b and itch: Key regulators of peripheral T-cell tolerance
    • Venuprasad, K. 2010. Cbl-b and itch: key regulators of peripheral T-cell tolerance. Cancer Res. 70: 3009-3012.
    • (2010) Cancer Res. , vol.70 , pp. 3009-3012
    • Venuprasad, K.1
  • 24
    • 0348134742 scopus 로고    scopus 로고
    • Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2
    • DOI 10.1126/science.1091362
    • Li, M., C. L. Brooks, F. Wu-Baer, D. Chen, R. Baer, and W. Gu. 2003. Monoversus polyubiquitination: differential control of p53 fate by Mdm2. Science 302: 1972-1975. (Pubitemid 37523506)
    • (2003) Science , vol.302 , Issue.5652 , pp. 1972-1975
    • Li, M.1    Brooks, C.L.2    Wu-Baer, F.3    Chen, D.4    Baer, R.5    Gu, W.6
  • 30
    • 0028027308 scopus 로고
    • Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain
    • DOI 10.1016/S0092-8674(94)90502-9
    • Treier, M., L. M. Staszewski, and D. Bohmann. 1994. Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain. Cell 78: 787-798. (Pubitemid 24294454)
    • (1994) Cell , vol.78 , Issue.5 , pp. 787-798
    • Treier, M.1    Staszewski, L.M.2    Bohmann, D.3
  • 31
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Y. Carrier, W. Gao, T. Korn, T. B. Strom, M. Oukka, H. L. Weiner, and V. K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 35
    • 0031919849 scopus 로고    scopus 로고
    • Jaks and STATs: Biological implications
    • Leonard, W. J., and J. J. O'Shea. 1998. Jaks and STATs: biological implications. Annu. Rev. Immunol. 16: 293-322.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 293-322
    • Leonard, W.J.1    O'Shea, J.J.2
  • 36
    • 0037379269 scopus 로고    scopus 로고
    • Transactivation of gp130 in myeloma cells
    • French, J. D., D. K. Walters, and D. F. Jelinek. 2003. Transactivation of gp130 in myeloma cells. J. Immunol. 170: 3717-3723.
    • (2003) J. Immunol. , vol.170 , pp. 3717-3723
    • French, J.D.1    Walters, D.K.2    Jelinek, D.F.3
  • 39
    • 49649119727 scopus 로고    scopus 로고
    • Tyk2-signaling plays an important role in host defense against Escherichia coli through IL-23-induced IL-17 production by gammadelta T cells
    • Nakamura, R., K. Shibata, H. Yamada, K. Shimoda, K. Nakayama, and Y. Yoshikai. 2008. Tyk2-signaling plays an important role in host defense against Escherichia coli through IL-23-induced IL-17 production by gammadelta T cells. J. Immunol. 181: 2071-2075.
    • (2008) J. Immunol. , vol.181 , pp. 2071-2075
    • Nakamura, R.1    Shibata, K.2    Yamada, H.3    Shimoda, K.4    Nakayama, K.5    Yoshikai, Y.6
  • 41
    • 0035340751 scopus 로고    scopus 로고
    • A heritable defect in IL-12 signaling in B10.Q/J mice. I. In vitro analysis
    • Ortmann, R., R. Smeltz, G. Yap, A. Sher, and E. M. Shevach. 2001. A heritable defect in IL-12 signaling in B10.Q/J mice. I. In vitro analysis. J. Immunol. 166: 5712-5719.
    • (2001) J. Immunol. , vol.166 , pp. 5712-5719
    • Ortmann, R.1    Smeltz, R.2    Yap, G.3    Sher, A.4    Shevach, E.M.5
  • 42
    • 36749010218 scopus 로고    scopus 로고
    • The Age of Crosstalk: Phosphorylation, Ubiquitination, and Beyond
    • DOI 10.1016/j.molcel.2007.11.019, PII S1097276507007988
    • Hunter, T. 2007. The age of crosstalk: phosphorylation, ubiquitination, and beyond. Mol. Cell 28: 730-738. (Pubitemid 350217067)
    • (2007) Molecular Cell , vol.28 , Issue.5 , pp. 730-738
    • Hunter, T.1
  • 43
    • 33751515474 scopus 로고    scopus 로고
    • The Polycomb Protein Ring1B Generates Self Atypical Mixed Ubiquitin Chains Required for Its in Vitro Histone H2A Ligase Activity
    • DOI 10.1016/j.molcel.2006.10.022, PII S1097276506007283
    • Ben-Saadon, R., D. Zaaroor, T. Ziv, and A. Ciechanover. 2006. The polycomb protein Ring1B generates self atypical mixed ubiquitin chains required for its in vitro histone H2A ligase activity. Mol. Cell 24: 701-711. (Pubitemid 44839211)
    • (2006) Molecular Cell , vol.24 , Issue.5 , pp. 701-711
    • Ben-Saadon, R.1    Zaaroor, D.2    Ziv, T.3    Ciechanover, A.4
  • 46
    • 78649372085 scopus 로고    scopus 로고
    • K33-linked polyubiquitination of T cell receptor-zeta regulates proteolysis-independent T cell signaling
    • Huang, H., M. S. Jeon, L. Liao, C. Yang, C. Elly, J. R. Yates, III, and Y. C. Liu. 2010. K33-linked polyubiquitination of T cell receptor-zeta regulates proteolysis-independent T cell signaling. Immunity 33: 60-70.
    • (2010) Immunity , vol.33 , pp. 60-70
    • Huang, H.1    Jeon, M.S.2    Liao, L.3    Yang, C.4    Elly, C.5    Yates III, J.R.6    Liu, Y.C.7
  • 47
    • 77950196277 scopus 로고    scopus 로고
    • T(H)17 cells in tumour immunity and immunotherapy
    • Zou, W., and N. P. Restifo. 2010. T(H)17 cells in tumour immunity and immunotherapy. Nat. Rev. Immunol. 10: 248-256.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 248-256
    • Zou, W.1    Restifo, N.P.2
  • 48
    • 30444443314 scopus 로고    scopus 로고
    • Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines
    • Zhou, G., C. G. Drake, and H. I. Levitsky. 2006. Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines. Blood 107: 628-636.
    • (2006) Blood , vol.107 , pp. 628-636
    • Zhou, G.1    Drake, C.G.2    Levitsky, H.I.3
  • 49
    • 51349123892 scopus 로고    scopus 로고
    • Cancer immunotherapy by dendritic cells
    • Melief, C. J. 2008. Cancer immunotherapy by dendritic cells. Immunity 29: 372-383.
    • (2008) Immunity , vol.29 , pp. 372-383
    • Melief, C.J.1
  • 55
    • 33846471122 scopus 로고    scopus 로고
    • Proteasome-independent functions of ubiquitin in endocytosis and signaling
    • DOI 10.1126/science.1127085
    • Mukhopadhyay, D., and H. Riezman. 2007. Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science 315: 201-205. (Pubitemid 46166358)
    • (2007) Science , vol.315 , Issue.5809 , pp. 201-205
    • Mukhopadhyay, D.1    Riezman, H.2
  • 56
    • 78650090605 scopus 로고    scopus 로고
    • Ubiquitin makes its mark on immune regulation
    • Malynn, B. A., and A. Ma. 2010. Ubiquitin makes its mark on immune regulation. Immunity 33: 843-852.
    • (2010) Immunity , vol.33 , pp. 843-852
    • Malynn, B.A.1    Ma, A.2
  • 57
    • 77956526505 scopus 로고    scopus 로고
    • TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains
    • Zucchelli, S., M. Codrich, F. Marcuzzi, M. Pinto, S. Vilotti, M. Biagioli, I. Ferrer, and S. Gustincich. 2010. TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains. Hum. Mol. Genet. 19: 3759-3770.
    • (2010) Hum. Mol. Genet. , vol.19 , pp. 3759-3770
    • Zucchelli, S.1    Codrich, M.2    Marcuzzi, F.3    Pinto, M.4    Vilotti, S.5    Biagioli, M.6    Ferrer, I.7    Gustincich, S.8
  • 58
    • 58149280817 scopus 로고    scopus 로고
    • Lysosomal localization of ubiquitinated Jun requires multiple determinants in a lysine-27-linked polyubiquitin conjugate
    • Ikeda, H., and T. K. Kerppola. 2008. Lysosomal localization of ubiquitinated Jun requires multiple determinants in a lysine-27-linked polyubiquitin conjugate. Mol. Biol. Cell 19: 4588-4601.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 4588-4601
    • Ikeda, H.1    Kerppola, T.K.2
  • 59
    • 0037073722 scopus 로고    scopus 로고
    • Nuclear translocation of plk1 mediated by its bipartite nuclear localization signal
    • Taniguchi, E., F. Toyoshima-Morimoto, and E. Nishida. 2002. Nuclear translocation of plk1 mediated by its bipartite nuclear localization signal. J. Biol. Chem. 277: 48884-48888.
    • (2002) J. Biol. Chem. , vol.277 , pp. 48884-48888
    • Taniguchi, E.1    Toyoshima-Morimoto, F.2    Nishida, E.3
  • 60
    • 69949136451 scopus 로고    scopus 로고
    • A unique sequence in the N-terminal regulatory region controls the nuclear localization of KLF8 by cooperating with the C-terminal zinc-fingers
    • Mehta, T. S., H. Lu, X. Wang, A. M. Urvalek, K. H. Nguyen, F. Monzur, J. D. Hammond, J. Q. Ma, and J. Zhao. 2009. A unique sequence in the N-terminal regulatory region controls the nuclear localization of KLF8 by cooperating with the C-terminal zinc-fingers. Cell Res. 19: 1098-1109.
    • (2009) Cell Res. , vol.19 , pp. 1098-1109
    • Mehta, T.S.1    Lu, H.2    Wang, X.3    Urvalek, A.M.4    Nguyen, K.H.5    Monzur, F.6    Hammond, J.D.7    Ma, J.Q.8    Zhao, J.9
  • 61
    • 0029029232 scopus 로고
    • Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins
    • LaCasse, E. C., and Y. A. Lefebvre. 1995. Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins. Nucleic Acids Res. 23: 1647-1656.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1647-1656
    • LaCasse, E.C.1    Lefebvre, Y.A.2
  • 62
    • 0030662523 scopus 로고    scopus 로고
    • F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
    • Skowyra, D., K. L. Craig, M. Tyers, S. J. Elledge, and J. W. Harper. 1997. F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91: 209-219.
    • (1997) Cell , vol.91 , pp. 209-219
    • Skowyra, D.1    Craig, K.L.2    Tyers, M.3    Elledge, S.J.4    Harper, J.W.5
  • 63
    • 71649114308 scopus 로고    scopus 로고
    • Autoimmune thyroiditis: A model uniquely suited to probe regulatory T cell function
    • Kong, Y. C., G. P. Morris, N. K. Brown, Y. Yan, J. C. Flynn, and C. S. David. 2009. Autoimmune thyroiditis: a model uniquely suited to probe regulatory T cell function. J. Autoimmun. 33: 239-246.
    • (2009) J. Autoimmun. , vol.33 , pp. 239-246
    • Kong, Y.C.1    Morris, G.P.2    Brown, N.K.3    Yan, Y.4    Flynn, J.C.5    David, C.S.6
  • 65
    • 44049104564 scopus 로고    scopus 로고
    • The differentiation of human T (H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
    • Manel, N., D. Unutmaz, and D. R. Littman. 2008. The differentiation of human T (H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat. Immunol. 9: 641-649.
    • (2008) Nat. Immunol. , vol.9 , pp. 641-649
    • Manel, N.1    Unutmaz, D.2    Littman, D.R.3


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