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Volumn 186, Issue 10, 2011, Pages 5527-5532

GM-CSF-based fusion cytokines as ligands for immune modulation

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE PROSTATE ISOENZYME; APC PROTEIN; CHEMOKINE RECEPTOR CCR2; CYCLOPHOSPHAMIDE; CYTOKINE; CYTOKINE ANTIBODY; DENDRITIC CELL VACCINE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2 ANTIBODY; FLUOROURACIL; FOLINIC ACID; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 16; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 3; INTERLEUKIN 3 ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; MYELIN BASIC PROTEIN; PEPTIDE DERIVATIVE; PLACEBO; PROTEIN ANTIBODY; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 79956192874     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003699     Document Type: Short Survey
Times cited : (19)

References (67)
  • 2
    • 0015694748 scopus 로고
    • Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
    • Rowley, J. D. 1973. Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature 243: 290-293.
    • (1973) Nature , vol.243 , pp. 290-293
    • Rowley, J.D.1
  • 3
    • 0037672877 scopus 로고    scopus 로고
    • Philadelphia chromosome-positive leukemias: From basic mechanisms to molecular therapeutics
    • Kurzrock, R., H. M. Kantarjian, B. J. Druker, and M. Talpaz. 2003. Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics. Ann. Intern. Med. 138: 819-830.
    • (2003) Ann. Intern. Med. , vol.138 , pp. 819-830
    • Kurzrock, R.1    Kantarjian, H.M.2    Druker, B.J.3    Talpaz, M.4
  • 4
    • 0030725775 scopus 로고    scopus 로고
    • The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells
    • Cortez, D., G. Reuther, and A. M. Pendergast. 1997. The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells. Oncogene 15: 2333-2342.
    • (1997) Oncogene , vol.15 , pp. 2333-2342
    • Cortez, D.1    Reuther, G.2    Pendergast, A.M.3
  • 5
    • 0027320006 scopus 로고
    • Enhancement of the biologic effects of interleukin-3 in vivo by anti-interleukin-3 antibodies
    • Jones, A. T., and H. J. Ziltener. 1993. Enhancement of the biologic effects of interleukin-3 in vivo by anti-interleukin-3 antibodies. Blood 82: 1133-1141.
    • (1993) Blood , vol.82 , pp. 1133-1141
    • Jones, A.T.1    Ziltener, H.J.2
  • 7
    • 38349056501 scopus 로고    scopus 로고
    • EGF-IL-18 fusion protein as a potential anti-tumor reagent by induction of immune response and apoptosis in cancer cells
    • Lu, J., Y. Peng, Z. J. Zheng, J. H. Pan, Y. Zhang, and Y. Bai. 2008. EGF-IL-18 fusion protein as a potential anti-tumor reagent by induction of immune response and apoptosis in cancer cells. Cancer Lett. 260: 187-197.
    • (2008) Cancer Lett. , vol.260 , pp. 187-197
    • Lu, J.1    Peng, Y.2    Zheng, Z.J.3    Pan, J.H.4    Zhang, Y.5    Bai, Y.6
  • 8
    • 22144440554 scopus 로고    scopus 로고
    • Rational design of an EGF-IL18 fusion protein: Implication for developing tumor therapeutics
    • Lu, J. X., Y. Peng, Z. F. Meng, L. Q. Jin, Y. S. Lu, and M. X. Guan. 2005. Rational design of an EGF-IL18 fusion protein: implication for developing tumor therapeutics. Biochem. Biophys. Res. Commun. 334: 157-161.
    • (2005) Biochem. Biophys. Res. Commun. , vol.334 , pp. 157-161
    • Lu, J.X.1    Peng, Y.2    Meng, Z.F.3    Jin, L.Q.4    Lu, Y.S.5    Guan, M.X.6
  • 11
    • 34548643873 scopus 로고    scopus 로고
    • A fusion protein consisting of IL-16 and the encephalitogenic peptide of myelin basic protein constitutes an antigen-specific tolerogenic vaccine that inhibits experimental autoimmune encephalomyelitis
    • Mannie, M. D., and D. J. Abbott. 2007. A fusion protein consisting of IL-16 and the encephalitogenic peptide of myelin basic protein constitutes an antigen-specific tolerogenic vaccine that inhibits experimental autoimmune encephalomyelitis. J. Immunol. 179: 1458-1465.
    • (2007) J. Immunol. , vol.179 , pp. 1458-1465
    • Mannie, M.D.1    Abbott, D.J.2
  • 13
    • 0033551843 scopus 로고    scopus 로고
    • Identification of a CD4 domain required for interleukin-16 binding and lymphocyte activation
    • Liu, Y., W. W. Cruikshank, T. O'Loughlin, P. O'Reilly, D. M. Center, and H. Kornfeld. 1999. Identification of a CD4 domain required for interleukin-16 binding and lymphocyte activation. J. Biol. Chem. 274: 23387-23395.
    • (1999) J. Biol. Chem. , vol.274 , pp. 23387-23395
    • Liu, Y.1    Cruikshank, W.W.2    O'Loughlin, T.3    O'Reilly, P.4    Center, D.M.5    Kornfeld, H.6
  • 14
    • 77950346727 scopus 로고    scopus 로고
    • A GMCSF-neuroantigen fusion protein is a potent tolerogen in experimental autoimmune encephalomyelitis (EAE) that is associated with efficient targeting of neuroantigen to APC
    • Blanchfield, J. L., and M. D. Mannie. 2010. A GMCSF-neuroantigen fusion protein is a potent tolerogen in experimental autoimmune encephalomyelitis (EAE) that is associated with efficient targeting of neuroantigen to APC. J. Leukoc. Biol. 87: 509-521.
    • (2010) J. Leukoc. Biol. , vol.87 , pp. 509-521
    • Blanchfield, J.L.1    Mannie, M.D.2
  • 15
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
    • O'Shea, J. J., M. Gadina, and R. D. Schreiber. 2002. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 109(Suppl.): S121-S131.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • O'Shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 17
    • 0346121599 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling and immunity
    • Kubo, M., T. Hanada, and A. Yoshimura. 2003. Suppressors of cytokine signaling and immunity. Nat. Immunol. 4: 1169-1176.
    • (2003) Nat. Immunol. , vol.4 , pp. 1169-1176
    • Kubo, M.1    Hanada, T.2    Yoshimura, A.3
  • 18
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signalling and immune regulation
    • Yoshimura, A., T. Naka, and M. Kubo. 2007. SOCS proteins, cytokine signalling and immune regulation. Nat. Rev. Immunol. 7: 454-465.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3
  • 19
    • 0029806613 scopus 로고    scopus 로고
    • Function and signal transduction mediated by the interleukin 3 receptor system in hematopoiesis
    • Hara, T., and A. Miyajima. 1996. Function and signal transduction mediated by the interleukin 3 receptor system in hematopoiesis. Stem Cells 14: 605-618. (Pubitemid 26404613)
    • (1996) Stem Cells , vol.14 , Issue.6 , pp. 605-618
    • Hara, T.1    Miyajima, A.2
  • 22
    • 7644227544 scopus 로고    scopus 로고
    • Short-term delay of Fas-stimulated apoptosis by GM-CSF as a result of temporary suppression of FADD recruitment in neutrophils: Evidence implicating phosphatidylinositol 3-kinase and MEK1-ERK1/2 pathways downstream of classical protein kinase C
    • Kotone-Miyahara, Y., K. Yamashita, K. K. Lee, S. Yonehara, T. Uchiyama, M. Sasada, and A. Takahashi. 2004. Short-term delay of Fas-stimulated apoptosis by GM-CSF as a result of temporary suppression of FADD recruitment in neutrophils: evidence implicating phosphatidylinositol 3-kinase and MEK1-ERK1/2 pathways downstream of classical protein kinase C. J. Leukoc. Biol. 76: 1047-1056.
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 1047-1056
    • Kotone-Miyahara, Y.1    Yamashita, K.2    Lee, K.K.3    Yonehara, S.4    Uchiyama, T.5    Sasada, M.6    Takahashi, A.7
  • 23
    • 46249090513 scopus 로고    scopus 로고
    • Colony-stimulating factors in inflammation and autoimmunity
    • Hamilton, J. A. 2008. Colony-stimulating factors in inflammation and autoimmunity. Nat. Rev. Immunol. 8: 533-544.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 533-544
    • Hamilton, J.A.1
  • 25
    • 0842278641 scopus 로고    scopus 로고
    • Dendritic cell maturation requires STAT1 and is under feedback regulation by suppressors of cytokine signaling
    • Jackson, S. H., C. R. Yu, R. M. Mahdi, S. Ebong, and C. E. Egwuagu. 2004. Dendritic cell maturation requires STAT1 and is under feedback regulation by suppressors of cytokine signaling. J. Immunol. 172: 2307-2315.
    • (2004) J. Immunol. , vol.172 , pp. 2307-2315
    • Jackson, S.H.1    Yu, C.R.2    Mahdi, R.M.3    Ebong, S.4    Egwuagu, C.E.5
  • 27
    • 0029118847 scopus 로고
    • In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: A phase I study
    • Vadhan-Raj, S., H. E. Broxmeyer, M. Andreeff, J. C. Bandres, E. S. Buescher, R. S. Benjamin, N. E. Papadopoulos, A. Burgess, S. Patel, C. Plager, et al. 1995. In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: a phase I study. Blood 86: 2098-2105.
    • (1995) Blood , vol.86 , pp. 2098-2105
    • Vadhan-Raj, S.1    Broxmeyer, H.E.2    Andreeff, M.3    Bandres, J.C.4    Buescher, E.S.5    Benjamin, R.S.6    Papadopoulos, N.E.7    Burgess, A.8    Patel, S.9    Plager, C.10
  • 29
    • 0029856812 scopus 로고    scopus 로고
    • Effects of PIXY321, a granulocyte-macrophage colony-stimulating factor/interleukin 3 fusion protein, on human tumor colony-forming units taken directly from patients
    • Izquierdo, M. A., D. Degen, E. Raymond, D. Caron, V. Ortiz, P. Banks, and D. D. Von Hoff. 1996. Effects of PIXY321, a granulocyte-macrophage colony-stimulating factor/interleukin 3 fusion protein, on human tumor colony-forming units taken directly from patients. Clin. Cancer Res. 2: 1713-1716.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 1713-1716
    • Izquierdo, M.A.1    Degen, D.2    Raymond, E.3    Caron, D.4    Ortiz, V.5    Banks, P.6    Von Hoff, D.D.7
  • 30
    • 0028255994 scopus 로고
    • Effects of PIXY321, a granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein, on chemotherapy-induced multilineage myelosuppression in patients with sarcoma
    • Vadhan-Raj, S., N. E. Papadopoulos, M. A. Burgess, K. A. Linke, S. R. Patel, C. Hays, A. Arcenas, C. Plager, A. P. Kudelka, W. N. Hittelman, et al. 1994. Effects of PIXY321, a granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein, on chemotherapy-induced multilineage myelosuppression in patients with sarcoma. J. Clin. Oncol. 12: 715-724.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 715-724
    • Vadhan-Raj, S.1    Papadopoulos, N.E.2    Burgess, M.A.3    Linke, K.A.4    Patel, S.R.5    Hays, C.6    Arcenas, A.7    Plager, C.8    Kudelka, A.P.9    Hittelman, W.N.10
  • 31
    • 5244233409 scopus 로고    scopus 로고
    • Prospective, randomized trial of 5-fluorouracil, leucovorin, doxorubicin, and cyclophosphamide chemotherapy in combination with the interleukin-3/ granulocyte-macrophage colony-stimulating factor (GM-CSF) fusion protein (PIXY321) versus GM-CSF in patients with advanced breast cancer
    • O'Shaughnessy, J. A., A. Tolcher, D. Riseberg, D. Venzon, J. Zujewski, M. Noone, M. Gossard, D. Danforth, J. Jacobson, V. Chang, et al. 1996. Prospective, randomized trial of 5-fluorouracil, leucovorin, doxorubicin, and cyclophosphamide chemotherapy in combination with the interleukin-3/granulocyte- macrophage colony-stimulating factor (GM-CSF) fusion protein (PIXY321) versus GM-CSF in patients with advanced breast cancer. Blood 87: 2205-2211.
    • (1996) Blood , vol.87 , pp. 2205-2211
    • O'Shaughnessy, J.A.1    Tolcher, A.2    Riseberg, D.3    Venzon, D.4    Zujewski, J.5    Noone, M.6    Gossard, M.7    Danforth, D.8    Jacobson, J.9    Chang, V.10
  • 32
    • 0035400054 scopus 로고    scopus 로고
    • Cutting edge: The common gamma-chain is an indispensable subunit of the IL-21 receptor complex
    • Asao, H., C. Okuyama, S. Kumaki, N. Ishii, S. Tsuchiya, D. Foster, and K. Sugamura. 2001. Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. J. Immunol. 167: 1-5. (Pubitemid 32567752)
    • (2001) Journal of Immunology , vol.167 , Issue.1 , pp. 1-5
    • Asao, H.1    Okuyama, C.2    Kumaki, S.3    Ishii, N.4    Tsuchiya, S.5    Foster, D.6    Sugamura, K.7
  • 33
    • 0035169507 scopus 로고    scopus 로고
    • Interleukin 15: Biology and relevance to human disease
    • Fehniger, T. A., and M. A. Caligiuri. 2001. Interleukin 15: biology and relevance to human disease. Blood 97: 14-32.
    • (2001) Blood , vol.97 , pp. 14-32
    • Fehniger, T.A.1    Caligiuri, M.A.2
  • 34
    • 0038813748 scopus 로고    scopus 로고
    • Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling
    • Kovanen, P. E., A. Rosenwald, J. Fu, E. M. Hurt, L. T. Lam, J. M. Giltnane, G. Wright, L. M. Staudt, and W. J. Leonard. 2003. Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling. J. Biol. Chem. 278: 5205-5213.
    • (2003) J. Biol. Chem. , vol.278 , pp. 5205-5213
    • Kovanen, P.E.1    Rosenwald, A.2    Fu, J.3    Hurt, E.M.4    Lam, L.T.5    Giltnane, J.M.6    Wright, G.7    Staudt, L.M.8    Leonard, W.J.9
  • 36
    • 38349123079 scopus 로고    scopus 로고
    • The opposite effects of IL-15 and IL-21 on CLL B cells correlate with differential activation of the JAK/STAT and ERK1/2 pathways
    • de Totero, D., R. Meazza, M. Capaia, M. Fabbi, B. Azzarone, E. Balleari, M. Gobbi, G. Cutrona, M. Ferrarini, and S. Ferrini. 2008. The opposite effects of IL-15 and IL-21 on CLL B cells correlate with differential activation of the JAK/STAT and ERK1/2 pathways. Blood 111: 517-524.
    • (2008) Blood , vol.111 , pp. 517-524
    • De Totero, D.1    Meazza, R.2    Capaia, M.3    Fabbi, M.4    Azzarone, B.5    Balleari, E.6    Gobbi, M.7    Cutrona, G.8    Ferrarini, M.9    Ferrini, S.10
  • 37
    • 34548422381 scopus 로고    scopus 로고
    • Interleukin-21 Activates Cytotoxic T Lymphocytes and Natural Killer Cells to Generate Antitumor Response in Mouse Renal Cell Carcinoma
    • DOI 10.1016/j.juro.2007.05.115, PII S0022534707013869
    • Kumano, M., I. Hara, J. Furukawa, S. Oniki, H. Nagai, H. Miyake, and M. Fujisawa. 2007. Interleukin-21 activates cytotoxic T lymphocytes and natural killer cells to generate antitumor response in mouse renal cell carcinoma. J. Urol. 178: 1504-1509. (Pubitemid 47368380)
    • (2007) Journal of Urology , vol.178 , Issue.4 , pp. 1504-1509
    • Kumano, M.1    Hara, I.2    Furukawa, J.3    Oniki, S.4    Nagai, H.5    Miyake, H.6    Fujisawa, M.7
  • 38
    • 33745298650 scopus 로고    scopus 로고
    • Interleukin-21 enhances NK cell activation in response to antibody-coated targets
    • Roda, J. M., R. Parihar, A. Lehman, A. Mani, S. Tridandapani, and W. E. Carson III. 2006. Interleukin-21 enhances NK cell activation in response to antibody-coated targets. J. Immunol. 177: 120-129.
    • (2006) J. Immunol. , vol.177 , pp. 120-129
    • Roda, J.M.1    Parihar, R.2    Lehman, A.3    Mani, A.4    Tridandapani, S.5    Carson III, W.E.6
  • 39
    • 38049120319 scopus 로고    scopus 로고
    • IL-21 mediated Foxp3 suppression leads to enhanced generation of antigen-specific CD8+ cytotoxic T lymphocytes
    • Li, Y., and C. Yee. 2008. IL-21 mediated Foxp3 suppression leads to enhanced generation of antigen-specific CD8+ cytotoxic T lymphocytes. Blood 111: 229-235.
    • (2008) Blood , vol.111 , pp. 229-235
    • Li, Y.1    Yee, C.2
  • 41
    • 10844248144 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor and interleukin-2 fusion cDNA for cancer gene immunotherapy
    • DOI 10.1158/0008-5472.CAN-04-1776
    • Stagg, J., J. H. Wu, N. Bouganim, and J. Galipeau. 2004. Granulocyte-macrophage colony-stimulating factor and interleukin-2 fusion cDNA for cancer gene immunotherapy. Cancer Res. 64: 8795-8799. (Pubitemid 39665478)
    • (2004) Cancer Research , vol.64 , Issue.24 , pp. 8795-8799
    • Stagg, J.1    Wu, J.H.2    Bouganim, N.3    Galipeau, J.4
  • 42
    • 71549128406 scopus 로고    scopus 로고
    • The human ortholog of granulocyte macrophage colony-stimulating factor and interleukin-2 fusion protein induces potent ex vivo natural killer cell activation and maturation
    • Published erratum appears in 2010 Cancer Res. 70: 6106
    • Penafuerte, C., N. Bautista-Lopez, M. R. Boulassel, J. P. Routy, and J. Galipeau. 2009. The human ortholog of granulocyte macrophage colony-stimulating factor and interleukin-2 fusion protein induces potent ex vivo natural killer cell activation and maturation. [Published erratum appears in 2010 Cancer Res. 70: 6106.] Cancer Res. 69: 9020-9028.
    • (2009) Cancer Res. , vol.69 , pp. 9020-9028
    • Penafuerte, C.1    Bautista-Lopez, N.2    Boulassel, M.R.3    Routy, J.P.4    Galipeau, J.5
  • 43
    • 0025147765 scopus 로고
    • Effect of recombinant human granulocyte-macrophage colony-stimulating factor administration on the lymphocyte subsets of patients with refractory aplastic anemia
    • Faisal, M., W. Cumberland, R. Champlin, and J. L. Fahey. 1990. Effect of recombinant human granulocyte-macrophage colony-stimulating factor administration on the lymphocyte subsets of patients with refractory aplastic anemia. Blood 76: 1580-1585.
    • (1990) Blood , vol.76 , pp. 1580-1585
    • Faisal, M.1    Cumberland, W.2    Champlin, R.3    Fahey, J.L.4
  • 44
    • 33847351791 scopus 로고    scopus 로고
    • AGMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex
    • DOI 10.1182/blood-2006-07-037473
    • Rafei, M., J. H. Wu, B. Annabi, L. Lejeune, M. François, and J. Galipeau. 2007. A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex. Blood 109: 2234-2242. (Pubitemid 46348228)
    • (2007) Blood , vol.109 , Issue.5 , pp. 2234-2242
    • Rafei, M.1    Jian, H.W.2    Annabi, B.3    Lejeune, L.4    Francois, M.5    Galipeaue, J.6
  • 45
    • 69949153114 scopus 로고    scopus 로고
    • A granulocyte-macrophage colony-stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties
    • Rafei, M., J. Hsieh, S. Zehntner, M. Li, K. Forner, E. Birman, M. N. Boivin, Y. K. Young, C. Perreault, and J. Galipeau. 2009. A granulocyte- macrophage colony-stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties. Nat. Med. 15: 1038-1045.
    • (2009) Nat. Med. , vol.15 , pp. 1038-1045
    • Rafei, M.1    Hsieh, J.2    Zehntner, S.3    Li, M.4    Forner, K.5    Birman, E.6    Boivin, M.N.7    Young, Y.K.8    Perreault, C.9    Galipeau, J.10
  • 46
    • 77954242768 scopus 로고    scopus 로고
    • A fusion of GMCSF and IL-21 initiates hypersignaling through the IL-21Ralpha chain with immune activating and tumoricidal effects in vivo
    • Williams, P., M. Rafei, M. Bouchentouf, J. Raven, S. Yuan, J. Cuerquis, K. A. Forner, E. Birman, and J. Galipeau. 2010. A fusion of GMCSF and IL-21 initiates hypersignaling through the IL-21Ralpha chain with immune activating and tumoricidal effects in vivo. Mol. Ther. 18: 1293-1301.
    • (2010) Mol. Ther. , vol.18 , pp. 1293-1301
    • Williams, P.1    Rafei, M.2    Bouchentouf, M.3    Raven, J.4    Yuan, S.5    Cuerquis, J.6    Forner, K.A.7    Birman, E.8    Galipeau, J.9
  • 49
    • 0032571360 scopus 로고    scopus 로고
    • Aminoterminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection
    • Proost, P., I. De Meester, D. Schols, S. Struyf, A. M. Lambeir, A. Wuyts, G. Opdenakker, E. De Clercq, S. Scharpé, and J. Van Damme. 1998. Aminoterminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection. J. Biol. Chem. 273: 7222-7227.
    • (1998) J. Biol. Chem. , vol.273 , pp. 7222-7227
    • Proost, P.1    De Meester, I.2    Schols, D.3    Struyf, S.4    Lambeir, A.M.5    Wuyts, A.6    Opdenakker, G.7    De Clercq, E.8    Scharpé, S.9    Van Damme, J.10
  • 50
    • 0030825407 scopus 로고    scopus 로고
    • Chemokines
    • Rollins, B. J. 1997. Chemokines. Blood 90: 909-928. (Pubitemid 27314123)
    • (1997) Blood , vol.90 , Issue.3 , pp. 909-928
    • Rollins, B.J.1
  • 51
  • 53
    • 0037458614 scopus 로고    scopus 로고
    • The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation
    • Tohgo, A., E. W. Choy, D. Gesty-Palmer, K. L. Pierce, S. Laporte, R. H. Oakley, M. G. Caron, R. J. Lefkowitz, and L. M. Luttrell. 2003. The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. J. Biol. Chem. 278: 6258-6267.
    • (2003) J. Biol. Chem. , vol.278 , pp. 6258-6267
    • Tohgo, A.1    Choy, E.W.2    Gesty-Palmer, D.3    Pierce, K.L.4    Laporte, S.5    Oakley, R.H.6    Caron, M.G.7    Lefkowitz, R.J.8    Luttrell, L.M.9
  • 54
    • 0024425113 scopus 로고
    • Role of the kidney in metabolic change of interleukin-2
    • Ohnishi, H., J. T. Chao, K. K. Lin, H. Lee, and T. M. Chu. 1989. Role of the kidney in metabolic change of interleukin-2. Tumour Biol. 10: 202-214.
    • (1989) Tumour Biol. , vol.10 , pp. 202-214
    • Ohnishi, H.1    Chao, J.T.2    Lin, K.K.3    Lee, H.4    Chu, T.M.5
  • 55
    • 58149388233 scopus 로고    scopus 로고
    • Mesenchymal stromal cell-derived CCL2 suppresses plasma cell immunoglobulin production via STAT3 inactivation and PAX5 induction
    • Rafei, M., J. Hsieh, S. Fortier, M. Li, S. Yuan, E. Birman, K. Forner, M. N. Boivin, K. Doody, M. Tremblay, et al. 2008. Mesenchymal stromal cell-derived CCL2 suppresses plasma cell immunoglobulin production via STAT3 inactivation and PAX5 induction. Blood 112: 4991-4998.
    • (2008) Blood , vol.112 , pp. 4991-4998
    • Rafei, M.1    Hsieh, J.2    Fortier, S.3    Li, M.4    Yuan, S.5    Birman, E.6    Forner, K.7    Boivin, M.N.8    Doody, K.9    Tremblay, M.10
  • 56
    • 0037103183 scopus 로고    scopus 로고
    • Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo
    • McQuibban, G. A., J. H. Gong, J. P. Wong, J. L. Wallace, I. Clark-Lewis, and C. M. Overall. 2002. Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo. Blood 100: 1160-1167.
    • (2002) Blood , vol.100 , pp. 1160-1167
    • McQuibban, G.A.1    Gong, J.H.2    Wong, J.P.3    Wallace, J.L.4    Clark-Lewis, I.5    Overall, C.M.6
  • 57
    • 0035911254 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis
    • Huang, D. R., J. Wang, P. Kivisakk, B. J. Rollins, and R. M. Ransohoff. 2001. Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis. J. Exp. Med. 193: 713-726.
    • (2001) J. Exp. Med. , vol.193 , pp. 713-726
    • Huang, D.R.1    Wang, J.2    Kivisakk, P.3    Rollins, B.J.4    Ransohoff, R.M.5
  • 58
    • 0036295472 scopus 로고    scopus 로고
    • Upregulation of monocyte chemotactic protein-1 and CC chemokine receptor 2 in the central nervous system is closely associated with relapse of autoimmune encephalomyelitis in Lewis rats
    • DOI 10.1016/S0165-5728(02)00147-9, PII S0165572802001479
    • Jee, Y., W. K. Yoon, Y. Okura, N. Tanuma, and Y. Matsumoto. 2002. Upregulation of monocyte chemotactic protein-1 and CC chemokine receptor 2 in the central nervous system is closely associated with relapse of autoimmune encephalomyelitis in Lewis rats. J. Neuroimmunol. 128: 49-57. (Pubitemid 34722363)
    • (2002) Journal of Neuroimmunology , vol.128 , Issue.1-2 , pp. 49-57
    • Jee, Y.1    Yoon, W.K.2    Okura, Y.3    Tanuma, N.4    Matsumoto, Y.5
  • 59
    • 0034596949 scopus 로고    scopus 로고
    • Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
    • Izikson, L., R. S. Klein, I. F. Charo, H. L. Weiner, and A. D. Luster. 2000. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J. Exp. Med. 192: 1075-1080.
    • (2000) J. Exp. Med. , vol.192 , pp. 1075-1080
    • Izikson, L.1    Klein, R.S.2    Charo, I.F.3    Weiner, H.L.4    Luster, A.D.5
  • 60
    • 77549086214 scopus 로고    scopus 로고
    • CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis
    • Zhang, J., L. Patel, and K. J. Pienta. 2010. CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis. Cytokine Growth Factor Rev. 21: 41-48.
    • (2010) Cytokine Growth Factor Rev. , vol.21 , pp. 41-48
    • Zhang, J.1    Patel, L.2    Pienta, K.J.3
  • 61
    • 0032800758 scopus 로고    scopus 로고
    • CCR2: From cloning to the creation of knockout mice
    • Charo, I. F. 1999. CCR2: from cloning to the creation of knockout mice. Chem. Immunol. 72: 30-41.
    • (1999) Chem. Immunol. , vol.72 , pp. 30-41
    • Charo, I.F.1
  • 62
    • 68149160827 scopus 로고    scopus 로고
    • An engineered GM-CSF-CCL2 fusokine is a potent inhibitor of CCR2-driven inflammation as demonstrated in a murine model of inflammatory arthritis
    • Rafei, M., Y. A. Berchiche, E. Birman, M. N. Boivin, Y. K. Young, J. H. Wu, N. Heveker, and J. Galipeau. 2009. An engineered GM-CSF-CCL2 fusokine is a potent inhibitor of CCR2-driven inflammation as demonstrated in a murine model of inflammatory arthritis. J. Immunol. 183: 1759-1766.
    • (2009) J. Immunol. , vol.183 , pp. 1759-1766
    • Rafei, M.1    Berchiche, Y.A.2    Birman, E.3    Boivin, M.N.4    Young, Y.K.5    Wu, J.H.6    Heveker, N.7    Galipeau, J.8
  • 63
    • 64849099402 scopus 로고    scopus 로고
    • Selective inhibition of CCR2 expressing lymphomyeloid cells in experimental autoimmune encephalomyelitis by a GM-CSF-MCP1 fusokine
    • Rafei, M., P. M. Campeau, J. H. Wu, E. Birman, K. Forner, M. N. Boivin, and J. Galipeau. 2009. Selective inhibition of CCR2 expressing lymphomyeloid cells in experimental autoimmune encephalomyelitis by a GM-CSF-MCP1 fusokine. J. Immunol. 182: 2620-2627.
    • (2009) J. Immunol. , vol.182 , pp. 2620-2627
    • Rafei, M.1    Campeau, P.M.2    Wu, J.H.3    Birman, E.4    Forner, K.5    Boivin, M.N.6    Galipeau, J.7
  • 64
    • 67651160649 scopus 로고    scopus 로고
    • CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
    • DeNardo, D. G., J. B. Barreto, P. Andreu, L. Vasquez, D. Tawfik, N. Kolhatkar, and L. M. Coussens. 2009. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16: 91-102.
    • (2009) Cancer Cell , vol.16 , pp. 91-102
    • DeNardo, D.G.1    Barreto, J.B.2    Andreu, P.3    Vasquez, L.4    Tawfik, D.5    Kolhatkar, N.6    Coussens, L.M.7
  • 66
    • 44749088863 scopus 로고    scopus 로고
    • The beta-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons
    • Edman, L. C., H. Mira, and E. Arenas. 2008. The beta-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons. Exp. Cell Res. 314: 2123-2130.
    • (2008) Exp. Cell Res. , vol.314 , pp. 2123-2130
    • Edman, L.C.1    Mira, H.2    Arenas, E.3
  • 67
    • 68149098592 scopus 로고    scopus 로고
    • The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity
    • Szymczak, W. A., and G. S. Deepe Jr. 2009. The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity. J. Immunol. 183: 1964-1974.
    • (2009) J. Immunol. , vol.183 , pp. 1964-1974
    • Szymczak, W.A.1    Deepe Jr., G.S.2


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