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Volumn 14, Issue 6, 1996, Pages 605-618

Function and signal transduction mediated by the interleukin 3 receptor system in hematopoiesis

Author keywords

Colony stimulating factor; Common subunit; Cytokine receptor; IL 3; JAK STAT pathway; Ras

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 3 RECEPTOR; INTERLEUKIN 5; PROTEIN TYROSINE KINASE; RAF PROTEIN; RAS PROTEIN; RECEPTOR SUBUNIT;

EID: 0029806613     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.140605     Document Type: Review
Times cited : (70)

References (99)
  • 1
    • 0023922373 scopus 로고
    • Purification and characterization of mouse hematopoietic stem cells
    • Spangrude GJ, Heimfeld S, Weissman IL. Purification and characterization of mouse hematopoietic stem cells. Science 1988;241:58-62.
    • (1988) Science , vol.241 , pp. 58-62
    • Spangrude, G.J.1    Heimfeld, S.2    Weissman, I.L.3
  • 2
    • 0026072652 scopus 로고
    • The in vitro response of phenotypically defined mouse stem cells and myeloerythroid progenitors to single or multiple growth factors
    • Heimfeld S, Hudak S, Weissman I et al. The in vitro response of phenotypically defined mouse stem cells and myeloerythroid progenitors to single or multiple growth factors. Proc Natl Acad Sci USA 1991;88:9902-9906.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 9902-9906
    • Heimfeld, S.1    Hudak, S.2    Weissman, I.3
  • 3
    • 0025285859 scopus 로고
    • Cytokines: Coordinators of immune and inflammatory responses
    • Arai K, Lee F, Miyajima A et al. Cytokines: coordinators of immune and inflammatory responses. Annu Rev Biochem 1990;59:783-836.
    • (1990) Annu Rev Biochem , vol.59 , pp. 783-836
    • Arai, K.1    Lee, F.2    Miyajima, A.3
  • 4
    • 0023818705 scopus 로고
    • T cell-replacing factor (TRF)/interleukin 5 (IL-5): Molecular and functional properties
    • Takatsu K, Tominaga A, Harada N et al. T cell-replacing factor (TRF)/interleukin 5 (IL-5): molecular and functional properties. Immunol Rev 1988;102:107-135.
    • (1988) Immunol Rev , vol.102 , pp. 107-135
    • Takatsu, K.1    Tominaga, A.2    Harada, N.3
  • 5
    • 0023498506 scopus 로고
    • + proB lymphocyte clones. Phenotype, growth requirements and differentiation in vitro and in vivo
    • + proB lymphocyte clones. Phenotype, growth requirements and differentiation in vitro and in vivo. EMBO J 1987;6:3687-3693.
    • (1987) EMBO J , vol.6 , pp. 3687-3693
    • Palacios, R.1    Karasuyama, H.2    Rolink, A.3
  • 6
    • 0026736730 scopus 로고
    • Common subunits of cytokine receptors and the functional redundancy of cytokines
    • Miyajima A, Hara T, Kitamura T. Common subunits of cytokine receptors and the functional redundancy of cytokines. TIBS 1992;17:378-382.
    • (1992) TIBS , vol.17 , pp. 378-382
    • Miyajima, A.1    Hara, T.2    Kitamura, T.3
  • 7
    • 0027489710 scopus 로고
    • Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5
    • Miyajima A, Mui AL, Ogorochi T et al. Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5. Blood 1993;82:1960-1974.
    • (1993) Blood , vol.82 , pp. 1960-1974
    • Miyajima, A.1    Mui, A.L.2    Ogorochi, T.3
  • 8
    • 0344655326 scopus 로고    scopus 로고
    • Hematopoiesis in mice lacking the entire granulocyte macrophage-colony stimulating factor/interleukin-3/interleukin-5 functions
    • Nishinakamura R, Miyajima A, Mee PJ et al. Hematopoiesis in mice lacking the entire granulocyte macrophage-colony stimulating factor/interleukin-3/interleukin-5 functions. Blood 1996;88:2458-2464.
    • (1996) Blood , vol.88 , pp. 2458-2464
    • Nishinakamura, R.1    Miyajima, A.2    Mee, P.J.3
  • 9
    • 0025861759 scopus 로고
    • Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for human IL-3 and GM-CSF receptors
    • Kitamura T, Sato N, Arai K et al. Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for human IL-3 and GM-CSF receptors. Cell 1991;66:1165-1174.
    • (1991) Cell , vol.66 , pp. 1165-1174
    • Kitamura, T.1    Sato, N.2    Arai, K.3
  • 10
    • 0026338754 scopus 로고
    • Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family
    • Murakami M, Narazali M, Hibi M et al. Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family. Proc Natl Acad Sci USA 1991;88:11349-11353.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 11349-11353
    • Murakami, M.1    Narazali, M.2    Hibi, M.3
  • 11
    • 0026607168 scopus 로고
    • Two distinct functional high affinity receptors for mouse IL-3
    • Hara T, Miyajima A. Two distinct functional high affinity receptors for mouse IL-3. EMBO J 1992;10:1875-1884.
    • (1992) EMBO J , vol.10 , pp. 1875-1884
    • Hara, T.1    Miyajima, A.2
  • 12
    • 0028920074 scopus 로고
    • Mice deficient for the IL-3/GM-CSF/IL-5 beta c receptor exhibit lung pathology and impaired immune response, while beta IL3 receptor-deficient mice are normal
    • Nishinakamura R, Nakayama N, Hirabayashi Y et al. Mice deficient for the IL-3/GM-CSF/IL-5 beta c receptor exhibit lung pathology and impaired immune response, while beta IL3 receptor-deficient mice are normal. Immunity 1995;2:211-222.
    • (1995) Immunity , vol.2 , pp. 211-222
    • Nishinakamura, R.1    Nakayama, N.2    Hirabayashi, Y.3
  • 13
    • 0029881372 scopus 로고    scopus 로고
    • Functional inactivation in mice of the gene for the interleukin-3 (IL-3)-specific receptor β-chain: Implication for IL-3 function and the mechanism of receptor transmodulation in hematopoietic cells
    • Nicola NA, Robb L, Metcalf D et al. Functional inactivation in mice of the gene for the interleukin-3 (IL-3)-specific receptor β-chain: implication for IL-3 function and the mechanism of receptor transmodulation in hematopoietic cells. Blood 1996;87:2665-2674.
    • (1996) Blood , vol.87 , pp. 2665-2674
    • Nicola, N.A.1    Robb, L.2    Metcalf, D.3
  • 14
    • 0028824907 scopus 로고
    • Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5
    • Robb L, Drinkwater CC, Metcalf D et al. Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5. Proc Natl Acad Sci USA 1995;92:9565-9569.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9565-9569
    • Robb, L.1    Drinkwater, C.C.2    Metcalf, D.3
  • 15
    • 0026689408 scopus 로고
    • Cytokine receptors and signal transduction
    • Miyajima A, Kitamura T, Harada N et al. Cytokine receptors and signal transduction. Annu Rev Immunol 1992;10:295-331.
    • (1992) Annu Rev Immunol , vol.10 , pp. 295-331
    • Miyajima, A.1    Kitamura, T.2    Harada, N.3
  • 16
    • 0029084805 scopus 로고
    • Interleukin-6 family of cytokines and gp130
    • Kishimoto T, Akira S, Narazaki M et al. Interleukin-6 family of cytokines and gp130. Blood 1995;86:1243-1254.
    • (1995) Blood , vol.86 , pp. 1243-1254
    • Kishimoto, T.1    Akira, S.2    Narazaki, M.3
  • 17
    • 0029933362 scopus 로고    scopus 로고
    • Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways
    • Wollert KC, Taga T, Saito M et al. Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways. J Biol Chem 1996;271:9535-9545.
    • (1996) J Biol Chem , vol.271 , pp. 9535-9545
    • Wollert, K.C.1    Taga, T.2    Saito, M.3
  • 18
    • 0028978898 scopus 로고
    • The common gamma-chain for multiple cytokine receptors
    • Sugamura K, Asao H, Kondo M et al. The common gamma-chain for multiple cytokine receptors. Adv Immunol 1995;59:225-277.
    • (1995) Adv Immunol , vol.59 , pp. 225-277
    • Sugamura, K.1    Asao, H.2    Kondo, M.3
  • 19
    • 0028183408 scopus 로고
    • The molecular basis of X-linked severe combined immunodeficiency: The role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c
    • Leonard WJ, Noguchi M, Russell SM et al. The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c. Immunol Rev 1994;138:61-86.
    • (1994) Immunol Rev , vol.138 , pp. 61-86
    • Leonard, W.J.1    Noguchi, M.2    Russell, S.M.3
  • 20
    • 0026733625 scopus 로고
    • Critical cytoplasmic domains of the common β subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation
    • Sakamaki K, Miyajima I, Kitamura T et al. Critical cytoplasmic domains of the common β subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation. EMBO J 1992;11:3541-3549.
    • (1992) EMBO J , vol.11 , pp. 3541-3549
    • Sakamaki, K.1    Miyajima, I.2    Kitamura, T.3
  • 21
    • 0027612766 scopus 로고
    • A critical role for the cytoplasmic domain of the granulocyte-macrophage colony-stimulating factor alpha receptor in mediating cell growth
    • Polotskaya A, Zhao Y, Lilly ML et al. A critical role for the cytoplasmic domain of the granulocyte-macrophage colony-stimulating factor alpha receptor in mediating cell growth. Cell Growth Differ 1993;4:523-531.
    • (1993) Cell Growth Differ , vol.4 , pp. 523-531
    • Polotskaya, A.1    Zhao, Y.2    Lilly, M.L.3
  • 22
    • 0028113506 scopus 로고
    • A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor α chain and its function in IL-5-mediated growth signal transduction
    • Takaki S, Kanazawa H, Shiba M et al. A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor α chain and its function in IL-5-mediated growth signal transduction. Mol Cell Biol 1994;14:7404-7413.
    • (1994) Mol Cell Biol , vol.14 , pp. 7404-7413
    • Takaki, S.1    Kanazawa, H.2    Shiba, M.3
  • 23
    • 0029598480 scopus 로고
    • Roles of the cytoplasmic domains of the alpha and beta subunits of human granulocyte-macrophage colony-stimulating factor receptor
    • Muto A, Watanabe S, Itoh T et al. Roles of the cytoplasmic domains of the alpha and beta subunits of human granulocyte-macrophage colony-stimulating factor receptor. J Allergy Clin Immunol 1995;96:1100-1114.
    • (1995) J Allergy Clin Immunol , vol.96 , pp. 1100-1114
    • Muto, A.1    Watanabe, S.2    Itoh, T.3
  • 24
    • 0027205338 scopus 로고
    • Ligand-dependent activation of chimeric receptors with the cytoplasmic domain of the interleukin-3 receptor beta subunit (beta IL3)
    • Sakamaki K, Wang HM, Miyajima I et al. Ligand-dependent activation of chimeric receptors with the cytoplasmic domain of the interleukin-3 receptor beta subunit (beta IL3). J Biol Chem 1993;268:15833-15839.
    • (1993) J Biol Chem , vol.268 , pp. 15833-15839
    • Sakamaki, K.1    Wang, H.M.2    Miyajima, I.3
  • 25
    • 0028945520 scopus 로고
    • High affinity chimeric human granulocyte-macrophage colony-stimulating factor receptor carrying the cytoplasmic domain of the beta subunit but not the alpha subunit transduces growth promoting signals in Ba/F3 cells
    • Muto A, Watanabe S, Miyajima A et al. High affinity chimeric human granulocyte-macrophage colony-stimulating factor receptor carrying the cytoplasmic domain of the beta subunit but not the alpha subunit transduces growth promoting signals in Ba/F3 cells. Biochem Biophys Res Commun 1995;208:368-375.
    • (1995) Biochem Biophys Res Commun , vol.208 , pp. 368-375
    • Muto, A.1    Watanabe, S.2    Miyajima, A.3
  • 26
    • 0028966569 scopus 로고
    • Sequential mutations in the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor beta-subunit genes are necessary for the complete conversion to growth autonomy mediated by a truncated beta C subunit
    • Hannemann J, Hara T, Kawai M et al. Sequential mutations in the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor beta-subunit genes are necessary for the complete conversion to growth autonomy mediated by a truncated beta C subunit. Mol Cell Biol 1995;15:2402-2412.
    • (1995) Mol Cell Biol , vol.15 , pp. 2402-2412
    • Hannemann, J.1    Hara, T.2    Kawai, M.3
  • 27
    • 0029151003 scopus 로고
    • Activating point mutations in the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors suggest the involvement of beta subunit dimerization and cell type-specific molecules in signalling
    • Jenkins BJ, D'Andrea R, Gonda TJ. Activating point mutations in the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors suggest the involvement of beta subunit dimerization and cell type-specific molecules in signalling. EMBO J 1995;14:4276-4287.
    • (1995) EMBO J , vol.14 , pp. 4276-4287
    • Jenkins, B.J.1    D'Andrea, R.2    Gonda, T.J.3
  • 28
    • 0028274280 scopus 로고
    • A mutation of the common receptor subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor, and IL-5 that leads to ligand independence and tumorigenicity
    • D'Andrea R, Rayner J, Moretti P et al. A mutation of the common receptor subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor, and IL-5 that leads to ligand independence and tumorigenicity. Blood 1994;83:2802-2808.
    • (1994) Blood , vol.83 , pp. 2802-2808
    • D'Andrea, R.1    Rayner, J.2    Moretti, P.3
  • 29
    • 0029925333 scopus 로고    scopus 로고
    • Extracellular tuncations of hβc, the common signaling subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-5, lead to ligand-independent activation
    • D'Andrea RJ, Barry SC, Moretti PAB et al. Extracellular tuncations of hβc, the common signaling subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-5, lead to ligand-independent activation. Blood 1996;87:2641-2648.
    • (1996) Blood , vol.87 , pp. 2641-2648
    • D'Andrea, R.J.1    Barry, S.C.2    Moretti, P.A.B.3
  • 30
    • 0025674093 scopus 로고
    • A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors
    • Souyri M, Vigon I, Penciolelli JF et al. A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors. Cell 1990;63:1137-1147.
    • (1990) Cell , vol.63 , pp. 1137-1147
    • Souyri, M.1    Vigon, I.2    Penciolelli, J.F.3
  • 31
    • 0026577197 scopus 로고
    • Homodimerization and constitutive activation of the erythropoietin receptor
    • Watowich SS, Yoshimura A, Longmore GD et al. Homodimerization and constitutive activation of the erythropoietin receptor. Proc Natl Acad Sci USA 1992;89:2140-2144.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2140-2144
    • Watowich, S.S.1    Yoshimura, A.2    Longmore, G.D.3
  • 32
    • 0024505028 scopus 로고
    • A point mutation in the neu oncogene mimics ligand induction of receptor aggregation
    • Weiner DB, Liu J, Cohen JA et al. A point mutation in the neu oncogene mimics ligand induction of receptor aggregation. Nature 1989;339:230-231.
    • (1989) Nature , vol.339 , pp. 230-231
    • Weiner, D.B.1    Liu, J.2    Cohen, J.A.3
  • 33
    • 0029894667 scopus 로고    scopus 로고
    • Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor α- and β-chain heterodimerization, which is required for receptor activation but not high-affinity binding
    • Stomski FC, Sun Q, Bagley CJ et al. Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor α- and β-chain heterodimerization, which is required for receptor activation but not high-affinity binding. Mol Cell Biol 1996;16:3035-3046.
    • (1996) Mol Cell Biol , vol.16 , pp. 3035-3046
    • Stomski, F.C.1    Sun, Q.2    Bagley, C.J.3
  • 34
    • 0029863519 scopus 로고    scopus 로고
    • The β subunit of human granulocyte-macrophage colony-stimulating factor receptor forms a homodimer and is activated via association with the α subunit
    • Muto A, Watanabe S, Miyajima A et al. The β subunit of human granulocyte-macrophage colony-stimulating factor receptor forms a homodimer and is activated via association with the α subunit. J Exp Med 1996;183:1911-1916.
    • (1996) J Exp Med , vol.183 , pp. 1911-1916
    • Muto, A.1    Watanabe, S.2    Miyajima, A.3
  • 35
    • 0027199126 scopus 로고
    • IL-6-induced homodimerization of gp 130 and associated activation of a tyrosine kinase
    • Murakami M, Hibi M, Nakagawa N et al. IL-6-induced homodimerization of gp 130 and associated activation of a tyrosine kinase. Science 1993;260:1808-1810.
    • (1993) Science , vol.260 , pp. 1808-1810
    • Murakami, M.1    Hibi, M.2    Nakagawa, N.3
  • 36
    • 0027320024 scopus 로고
    • LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor
    • Davis S, Aldrich TH, Stahl N et al. LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. Science 1993;260:1805-1808.
    • (1993) Science , vol.260 , pp. 1805-1808
    • Davis, S.1    Aldrich, T.H.2    Stahl, N.3
  • 37
    • 0027521857 scopus 로고
    • Dimer- and oligomerization of the erythropoietin receptor by disulfide bond formation and significance of the region near the WSXWS motif in intracellular transport
    • Miura O, Ihle JN. Dimer- and oligomerization of the erythropoietin receptor by disulfide bond formation and significance of the region near the WSXWS motif in intracellular transport. Arch Biochem Biophys 1993;306:200-208.
    • (1993) Arch Biochem Biophys , vol.306 , pp. 200-208
    • Miura, O.1    Ihle, J.N.2
  • 38
    • 0028832719 scopus 로고
    • Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity
    • Alexander WS, Metcalf D, Dunn AR. Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity. EMBO J 1995;14:5569-5578.
    • (1995) EMBO J , vol.14 , pp. 5569-5578
    • Alexander, W.S.1    Metcalf, D.2    Dunn, A.R.3
  • 39
    • 0025166690 scopus 로고
    • Purification and characterization of the receptor for murine granulocyte colony-stimulating factor
    • Fukunaga R, Ishizaka-Ikeda E, Nagata S. Purification and characterization of the receptor for murine granulocyte colony-stimulating factor. J Biol Chem 1990;265:14008-14015.
    • (1990) J Biol Chem , vol.265 , pp. 14008-14015
    • Fukunaga, R.1    Ishizaka-Ikeda, E.2    Nagata, S.3
  • 40
    • 0026598960 scopus 로고
    • Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
    • de Vos AM, Ultsch M, Kossiakoff AA. Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science 1992;255:306-312.
    • (1992) Science , vol.255 , pp. 306-312
    • De Vos, A.M.1    Ultsch, M.2    Kossiakoff, A.A.3
  • 41
    • 0027965825 scopus 로고
    • JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization
    • Rui H, Lebrun JJ, Kirken RA et al. JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization. Endocrinology 1994;135:1299-1306.
    • (1994) Endocrinology , vol.135 , pp. 1299-1306
    • Rui, H.1    Lebrun, J.J.2    Kirken, R.A.3
  • 42
    • 0026731823 scopus 로고
    • Purification of murine interleukin 3 receptor
    • Mui AL-F, Kay RJ, Humphries RK et al. Purification of murine interleukin 3 receptor. J Biol Chem 1992;267:16523-16530.
    • (1992) J Biol Chem , vol.267 , pp. 16523-16530
    • Mui, A.L.-F.1    Kay, R.J.2    Humphries, R.K.3
  • 43
    • 0026808525 scopus 로고
    • Tyrosine phosphorylation of receptor beta subunits and common substrates in response to interleukin-3 and granulocyte-macrophage colony-stimulating factor
    • Duronio V, Clark-Lewis I, Federsppiel B et al. Tyrosine phosphorylation of receptor beta subunits and common substrates in response to interleukin-3 and granulocyte-macrophage colony-stimulating factor. J Biol Chem 1992;267:21856-21863.
    • (1992) J Biol Chem , vol.267 , pp. 21856-21863
    • Duronio, V.1    Clark-Lewis, I.2    Federsppiel, B.3
  • 44
    • 0027494821 scopus 로고
    • Signal transduction by the high-affinity GM-CSF receptor: Two distinct cytoplasmic regions of the common beta subunit responsible for different signaling
    • Sato N, Sakamaki K, Terada N et al. Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signaling. EMBO J 1993;12:4181-4189.
    • (1993) EMBO J , vol.12 , pp. 4181-4189
    • Sato, N.1    Sakamaki, K.2    Terada, N.3
  • 45
    • 0028068607 scopus 로고
    • Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3′-kinase
    • Welham MJ, Dechert U, Leslie KB et al. Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3′-kinase. J Biol Chem 1994;269:23764-23768.
    • (1994) J Biol Chem , vol.269 , pp. 23764-23768
    • Welham, M.J.1    Dechert, U.2    Leslie, K.B.3
  • 46
    • 0028985012 scopus 로고
    • Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM-CSF, IL-3 and steel factor and is constitutively increased by p210BCR/ABL
    • Matsuguchi T, Inhorn RC, Carlesso N et al. Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM-CSF, IL-3 and steel factor and is constitutively increased by p210BCR/ABL. EMBO J 1995;14:257-265.
    • (1995) EMBO J , vol.14 , pp. 257-265
    • Matsuguchi, T.1    Inhorn, R.C.2    Carlesso, N.3
  • 47
    • 0027485538 scopus 로고
    • Multiple cytokines induce the tyrosine phosphorylation of She and its association with Grb2 in hemopoietic cells
    • Cutler RL, Liu L, Damen JE et al. Multiple cytokines induce the tyrosine phosphorylation of She and its association with Grb2 in hemopoietic cells. J Biol Chem 1993;268:21463-21465.
    • (1993) J Biol Chem , vol.268 , pp. 21463-21465
    • Cutler, R.L.1    Liu, L.2    Damen, J.E.3
  • 48
    • 0028123081 scopus 로고
    • Multiple hemopoietins, with the exception of interleukin-4, induce modification of Shc and mSos1, but not their translocation
    • Welham MJ, Duronio V, Leslie KB et al. Multiple hemopoietins, with the exception of interleukin-4, induce modification of Shc and mSos1, but not their translocation. J Biol Chem 1994;269:21165-21176.
    • (1994) J Biol Chem , vol.269 , pp. 21165-21176
    • Welham, M.J.1    Duronio, V.2    Leslie, K.B.3
  • 49
    • 0027939947 scopus 로고
    • Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and Steel factor and is constitutively increased by p210BCR/ABL
    • Matsuguchi T, Salgia R, Hallek M et al. Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and Steel factor and is constitutively increased by p210BCR/ABL. J Biol Chem 1994;269:5016-5021.
    • (1994) J Biol Chem , vol.269 , pp. 5016-5021
    • Matsuguchi, T.1    Salgia, R.2    Hallek, M.3
  • 50
    • 0027488637 scopus 로고
    • Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis
    • Yi T, Mui AL, Krystal G et al. Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis. Mol Cell Biol 1993;13:7577-7586.
    • (1993) Mol Cell Biol , vol.13 , pp. 7577-7586
    • Yi, T.1    Mui, A.L.2    Krystal, G.3
  • 51
    • 0028956353 scopus 로고
    • Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
    • Klingmuller U, Lorenz U, Cantley LC et al. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 1995;80:729-738.
    • (1995) Cell , vol.80 , pp. 729-738
    • Klingmuller, U.1    Lorenz, U.2    Cantley, L.C.3
  • 52
    • 0026623013 scopus 로고
    • Interleukin-3 regulates the activity of the Lyn protein-tyrosine kinase in myeloid-committed leukemic cell lines
    • Torigoe T, O'Conner R, Santoli D et al. Interleukin-3 regulates the activity of the Lyn protein-tyrosine kinase in myeloid-committed leukemic cell lines. Blood 1992;80:617-624.
    • (1992) Blood , vol.80 , pp. 617-624
    • Torigoe, T.1    O'Conner, R.2    Santoli, D.3
  • 53
    • 0027413034 scopus 로고
    • C-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3
    • Hanazono Y, Chiba S, Sasaki K et al. c-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3. EMBO J 1993;12:1641-1646.
    • (1993) EMBO J , vol.12 , pp. 1641-1646
    • Hanazono, Y.1    Chiba, S.2    Sasaki, K.3
  • 54
    • 0028947836 scopus 로고
    • Tec protein-tyrosine kinase is involved in interleukin-3 signaling pathway
    • Mano H, Yamashita Y, Sato K et al. Tec protein-tyrosine kinase is involved in interleukin-3 signaling pathway. Blood 1995;85:343-350.
    • (1995) Blood , vol.85 , pp. 343-350
    • Mano, H.1    Yamashita, Y.2    Sato, K.3
  • 55
    • 0028999058 scopus 로고
    • Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain
    • Li T, Tsukada S, Satterthwaite A et al. Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain. Immunity 1995;2:451-460.
    • (1995) Immunity , vol.2 , pp. 451-460
    • Li, T.1    Tsukada, S.2    Satterthwaite, A.3
  • 56
    • 0028845212 scopus 로고
    • Cytokine receptor signalling
    • Ihle JN. Cytokine receptor signalling. Nature 1995;377:591-594.
    • (1995) Nature , vol.377 , pp. 591-594
    • Ihle, J.N.1
  • 57
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE Jr., Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994;264:1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 58
    • 0030046753 scopus 로고    scopus 로고
    • STATs: Signal transducers and activators of transcription
    • Ihle JN. STATs: signal transducers and activators of transcription. Cell 1996;84:331-334.
    • (1996) Cell , vol.84 , pp. 331-334
    • Ihle, J.N.1
  • 59
    • 0028180569 scopus 로고
    • JAK2 associates with the βc chain of the receptor for GM-CSF and its activation requires the membrane proximal region
    • Quelle FW, Witthuhn BA, Inhorn R et al. JAK2 associates with the βc chain of the receptor for GM-CSF and its activation requires the membrane proximal region. Mol Cell Biol 1994;14:4335-4341.
    • (1994) Mol Cell Biol , vol.14 , pp. 4335-4341
    • Quelle, F.W.1    Witthuhn, B.A.2    Inhorn, R.3
  • 60
    • 15844389026 scopus 로고    scopus 로고
    • JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells
    • Watanabe S, Itoh T, Arai K. JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells. J Biol Chem 1996;271:12681-12686.
    • (1996) J Biol Chem , vol.271 , pp. 12681-12686
    • Watanabe, S.1    Itoh, T.2    Arai, K.3
  • 61
    • 0028963550 scopus 로고
    • Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STATS homologs
    • Mui AL, Wakao H, O'Farrell AM et al. Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STATS homologs. EMBO J 1995;14:1166-1175.
    • (1995) EMBO J , vol.14 , pp. 1166-1175
    • Mui, A.L.1    Wakao, H.2    O'Farrell, A.M.3
  • 62
    • 0028916417 scopus 로고
    • Interleukin-3 signals through multiple isoforms of Stat5
    • Azam M, Erdjument-Bromage H, Kreider BL et al. Interleukin-3 signals through multiple isoforms of Stat5. EMBO J 1995;14:1402-1411.
    • (1995) EMBO J , vol.14 , pp. 1402-1411
    • Azam, M.1    Erdjument-Bromage, H.2    Kreider, B.L.3
  • 63
    • 0029060110 scopus 로고
    • Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways
    • Wakao H, Harada N, Kitamura T et al. Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways. EMBO J 1995;14:2527-2535.
    • (1995) EMBO J , vol.14 , pp. 2527-2535
    • Wakao, H.1    Harada, N.2    Kitamura, T.3
  • 64
    • 0029066310 scopus 로고
    • Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity
    • Gouilleux F, Pallard C, Dusanter-Fourt I et al. Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity. EMBO J 1995;14:2005-2013.
    • (1995) EMBO J , vol.14 , pp. 2005-2013
    • Gouilleux, F.1    Pallard, C.2    Dusanter-Fourt, I.3
  • 65
    • 0029588429 scopus 로고
    • Thrombopoietin induces activation of at least two distinct signaling pathways
    • Nagata Y, Todokoro K. Thrombopoietin induces activation of at least two distinct signaling pathways. FEBS Lett 1995;377:497-501.
    • (1995) FEBS Lett , vol.377 , pp. 497-501
    • Nagata, Y.1    Todokoro, K.2
  • 66
    • 0028217452 scopus 로고
    • Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response
    • Wakao H, Gouilleux F, Groner B. Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response. EMBO J 1994;13:2182-2191.
    • (1994) EMBO J , vol.13 , pp. 2182-2191
    • Wakao, H.1    Gouilleux, F.2    Groner, B.3
  • 67
    • 0027972046 scopus 로고
    • An interleukin-4-induced transcription factor: IL-4 Stat
    • Hou J, Schindler U, Henzel WJ et al. An interleukin-4-induced transcription factor: IL-4 Stat. Science 1994;265:1701-1706.
    • (1994) Science , vol.265 , pp. 1701-1706
    • Hou, J.1    Schindler, U.2    Henzel, W.J.3
  • 68
    • 0029057858 scopus 로고
    • Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis
    • Quelle FW, Shimoda K, Thierfelder W et al. Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis. Mol Cell Biol 1995;1555:3336-3343.
    • (1995) Mol Cell Biol , vol.1555 , pp. 3336-3343
    • Quelle, F.W.1    Shimoda, K.2    Thierfelder, W.3
  • 69
    • 0028303977 scopus 로고
    • Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
    • Akira S, Nishio Y, Inoue M et al. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 1994;77:63-71.
    • (1994) Cell , vol.77 , pp. 63-71
    • Akira, S.1    Nishio, Y.2    Inoue, M.3
  • 70
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • Zhong Z, Wen Z, Darnell JE Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994;264:95-98.
    • (1994) Science , vol.264 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell Jr., J.E.3
  • 71
    • 0028837491 scopus 로고
    • Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors
    • Kinoshita T, Yokota T, Arai K et al. Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors. EMBO J 1995;14:266-275.
    • (1995) EMBO J , vol.14 , pp. 266-275
    • Kinoshita, T.1    Yokota, T.2    Arai, K.3
  • 72
    • 0029014206 scopus 로고
    • A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
    • Yoshimura A, Ohkubo T, Kiguchi T et al. A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J 1995;14:2816-2826.
    • (1995) EMBO J , vol.14 , pp. 2816-2826
    • Yoshimura, A.1    Ohkubo, T.2    Kiguchi, T.3
  • 73
    • 0029870042 scopus 로고    scopus 로고
    • Mouse oncostatin M: An immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway
    • Yoshimura A, Ichihara M, Kinjyo I et al. Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway. EMBO J 1996;15:1055-1063.
    • (1996) EMBO J , vol.15 , pp. 1055-1063
    • Yoshimura, A.1    Ichihara, M.2    Kinjyo, I.3
  • 74
    • 0029892399 scopus 로고    scopus 로고
    • Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: Role of Stat5 in proliferation
    • Mui AL-F, Wakao H, Kinoshita T et al. Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation. EMBO J 1996;15:2425-2433.
    • (1996) EMBO J , vol.15 , pp. 2425-2433
    • Mui, A.L.-F.1    Wakao, H.2    Kinoshita, T.3
  • 75
    • 0029068012 scopus 로고
    • Transcriptional induction of pim-1 protein kinase gene expression by interferon gamma and post-transcriptional effects on costimulation with steel factor
    • Yip-Schneider MT, Horie M, Broxmeyer HE. Transcriptional induction of pim-1 protein kinase gene expression by interferon gamma and post-transcriptional effects on costimulation with steel factor. Blood 1995;85:3494-3502.
    • (1995) Blood , vol.85 , pp. 3494-3502
    • Yip-Schneider, M.T.1    Horie, M.2    Broxmeyer, H.E.3
  • 76
    • 0028815466 scopus 로고
    • A novel enhancer, the pro-B enhancer, regulates Id1 gene expression in progenitor B cells
    • Saisanit S, Sun XH. A novel enhancer, the pro-B enhancer, regulates Id1 gene expression in progenitor B cells. Mol Cell Biol 1995;15:1513-1521.
    • (1995) Mol Cell Biol , vol.15 , pp. 1513-1521
    • Saisanit, S.1    Sun, X.H.2
  • 77
    • 0028088556 scopus 로고
    • Constitutive expression of the Id1 gene impairs mouse B cell development
    • Sun XH. Constitutive expression of the Id1 gene impairs mouse B cell development. Cell 1994;79:893-900.
    • (1994) Cell , vol.79 , pp. 893-900
    • Sun, X.H.1
  • 78
    • 0022100028 scopus 로고
    • Proviral activation of the putative oncogene Pim-1 in MuLV induced T-cell lymphomas
    • Selten G, Cuypers HT, Berns A. Proviral activation of the putative oncogene Pim-1 in MuLV induced T-cell lymphomas. EMBO J 1985;4:1793-1798.
    • (1985) EMBO J , vol.4 , pp. 1793-1798
    • Selten, G.1    Cuypers, H.T.2    Berns, A.3
  • 79
    • 0029887634 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signaling
    • Itoh T, Muto A, Watanabe S et al. Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signaling. J Biol Chem 1996;271:7587-7592.
    • (1996) J Biol Chem , vol.271 , pp. 7587-7592
    • Itoh, T.1    Muto, A.2    Watanabe, S.3
  • 80
    • 0029033866 scopus 로고
    • Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells
    • Kinoshita T, Yokota T, Arai K et al. Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells. Oncogene 1995;10:2207-2212.
    • (1995) Oncogene , vol.10 , pp. 2207-2212
    • Kinoshita, T.1    Yokota, T.2    Arai, K.3
  • 81
    • 0030045594 scopus 로고    scopus 로고
    • Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia
    • Largaespada DA, Brannan CI, Jenkins NA et al. Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia. Nat Genet 1996;12:137-143.
    • (1996) Nat Genet , vol.12 , pp. 137-143
    • Largaespada, D.A.1    Brannan, C.I.2    Jenkins, N.A.3
  • 82
    • 0025164275 scopus 로고
    • Cloning and expression of a gene encoding an interleukin 3 receptor-like protein: Identification of another member of the cytokine receptor gene family
    • Gorman DM, Itoh N, Kitamura T et al. Cloning and expression of a gene encoding an interleukin 3 receptor-like protein: identification of another member of the cytokine receptor gene family. Proc Natl Acad Sci USA 1990;87:5459-5463.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5459-5463
    • Gorman, D.M.1    Itoh, N.2    Kitamura, T.3
  • 84
    • 0029123410 scopus 로고
    • Expression and selective cellular localization of granulocyte-macrophage colony-stimulating factor (GM-CSF) and GM-CSF alpha and beta receptor messenger ribonucleic acid and protein in human ovarian tissue
    • Zhao Y, Rong H, Chegini N. Expression and selective cellular localization of granulocyte-macrophage colony-stimulating factor (GM-CSF) and GM-CSF alpha and beta receptor messenger ribonucleic acid and protein in human ovarian tissue. Biol Reprod 1995;53:923-930.
    • (1995) Biol Reprod , vol.53 , pp. 923-930
    • Zhao, Y.1    Rong, H.2    Chegini, N.3
  • 85
    • 0027489249 scopus 로고
    • Identification and characterization of a high-affinity granulocyte-macrophage colony-stimulating factor receptor on primary rat oligodendrocytes
    • Baldwin GC, Benveniste EN, Chung GY et al. Identification and characterization of a high-affinity granulocyte-macrophage colony-stimulating factor receptor on primary rat oligodendrocytes. Blood 1993;82:3279-82.
    • (1993) Blood , vol.82 , pp. 3279-3282
    • Baldwin, G.C.1    Benveniste, E.N.2    Chung, G.Y.3
  • 86
    • 0027327477 scopus 로고
    • Expression and factor-dependent modulation of the interleukin-3 receptor subunits on human hematopoietic cells
    • Sato N, Caux C, Kitamura T et al. Expression and factor-dependent modulation of the interleukin-3 receptor subunits on human hematopoietic cells. Blood 1993;82:752-761.
    • (1993) Blood , vol.82 , pp. 752-761
    • Sato, N.1    Caux, C.2    Kitamura, T.3
  • 87
    • 0026911105 scopus 로고
    • Role of the interleukin 5 receptor system in hematopoiesis: Molecular basis for overlapping function of cytokines
    • Tominaga A, Takaki S, Hitoshi Y et al. Role of the interleukin 5 receptor system in hematopoiesis: molecular basis for overlapping function of cytokines. Bioessays 1992;14:527-533.
    • (1992) Bioessays , vol.14 , pp. 527-533
    • Tominaga, A.1    Takaki, S.2    Hitoshi, Y.3
  • 88
    • 0028918543 scopus 로고
    • Multicolony stimulating activity of interleukin 5 (IL-5) on hematopoietic progenitors from transgenic mice that express IL-5 receptor alpha subunit constitutively
    • Takagi M, Hara T, Ichiharu M et al. Multicolony stimulating activity of interleukin 5 (IL-5) on hematopoietic progenitors from transgenic mice that express IL-5 receptor alpha subunit constitutively. J Exp Med 1995;181:889-899.
    • (1995) J Exp Med , vol.181 , pp. 889-899
    • Takagi, M.1    Hara, T.2    Ichiharu, M.3
  • 89
    • 0027135814 scopus 로고
    • Induction of erythroid-specific gene expression in lymphoid cells
    • Chiba T, Nagata Y, Kishi A et al. Induction of erythroid-specific gene expression in lymphoid cells. Proc Natl Acad Sci USA 1993;90:11593-11597.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11593-11597
    • Chiba, T.1    Nagata, Y.2    Kishi, A.3
  • 91
    • 0028857266 scopus 로고
    • Erythropoietin and interleukin-3 induce distinct events in erythropoietin receptor-expressing BA/F3 cells
    • Krosl J, Damen JE, Krystal G et al. Erythropoietin and interleukin-3 induce distinct events in erythropoietin receptor-expressing BA/F3 cells. Blood 1995;85:50-56.
    • (1995) Blood , vol.85 , pp. 50-56
    • Krosl, J.1    Damen, J.E.2    Krystal, G.3
  • 92
    • 0028278740 scopus 로고
    • A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells
    • Longmore GD, Pharr PN, Lodish HF. A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells. Mol Cell Biol 1994;14:2266-2277.
    • (1994) Mol Cell Biol , vol.14 , pp. 2266-2277
    • Longmore, G.D.1    Pharr, P.N.2    Lodish, H.F.3
  • 93
    • 0028960271 scopus 로고
    • The murine interleukin-3 receptor alpha subunit gene: Chromosomal localization, genomic structure, and promoter function
    • Miyajima I, Levitt L, Hara T et al. The murine interleukin-3 receptor alpha subunit gene: chromosomal localization, genomic structure, and promoter function. Blood 1995;85:1246-1253.
    • (1995) Blood , vol.85 , pp. 1246-1253
    • Miyajima, I.1    Levitt, L.2    Hara, T.3
  • 94
    • 0025073137 scopus 로고
    • Interleukin 3 alone does not support the proliferation of bone marrow cells from A/J mice: A novel system for studying the synergistic activities of IL-3
    • Morris CF, Salisbury J, Kobayashi M et al. Interleukin 3 alone does not support the proliferation of bone marrow cells from A/J mice: a novel system for studying the synergistic activities of IL-3. Br J Haematol 1990;74:131-137.
    • (1990) Br J Haematol , vol.74 , pp. 131-137
    • Morris, C.F.1    Salisbury, J.2    Kobayashi, M.3
  • 95
    • 0028923474 scopus 로고
    • Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene
    • Ichihara M, Hara T, Takagi M et al. Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene. EMBO J 1995;14:939-950.
    • (1995) EMBO J , vol.14 , pp. 939-950
    • Ichihara, M.1    Hara, T.2    Takagi, M.3
  • 96
    • 0029866743 scopus 로고    scopus 로고
    • Genetic basis of hypo-responsiveness of A/J mice to interleukin-3
    • Leslie KB, Jalbert S, Orban P et al. Genetic basis of hypo-responsiveness of A/J mice to interleukin-3. Blood 1996;87:3186-3194.
    • (1996) Blood , vol.87 , pp. 3186-3194
    • Leslie, K.B.1    Jalbert, S.2    Orban, P.3
  • 97
    • 0028943376 scopus 로고
    • Interleukin-3 (IL-3) poor-responsive inbred mouse strains carry the identical deletion of a branch point in the IL-3 receptor alpha subunit gene
    • Hara T, Ichihara M, Takagi M et al. Interleukin-3 (IL-3) poor-responsive inbred mouse strains carry the identical deletion of a branch point in the IL-3 receptor alpha subunit gene. Blood 1995;85:2331-2336.
    • (1995) Blood , vol.85 , pp. 2331-2336
    • Hara, T.1    Ichihara, M.2    Takagi, M.3
  • 98
    • 0028263504 scopus 로고
    • Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis
    • Dranoff G, Crawford AD, Sadelain M et al. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science 1994;264:713-716.
    • (1994) Science , vol.264 , pp. 713-716
    • Dranoff, G.1    Crawford, A.D.2    Sadelain, M.3
  • 99
    • 0026695804 scopus 로고
    • Chromosomal localization and organization of the murine genes encoding the β subunits (AIC2A and AIC2B) of the interleukin 3, granulocyte/macrophage colony-stimulating factor and interleukin 5 receptors
    • Gorman DM, Itoh N, Jenkins NA et al. Chromosomal localization and organization of the murine genes encoding the β subunits (AIC2A and AIC2B) of the interleukin 3, granulocyte/macrophage colony-stimulating factor and interleukin 5 receptors. J Biol Chem 1992;267:15842-15848.
    • (1992) J Biol Chem , vol.267 , pp. 15842-15848
    • Gorman, D.M.1    Itoh, N.2    Jenkins, N.A.3


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