메뉴 건너뛰기




Volumn 72, Issue , 1999, Pages 30-41

CCR2: From cloning to the creation of knockout mice

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; CHEMOKINE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; VIRUS RECEPTOR;

EID: 0032800758     PISSN: 10150145     EISSN: None     Source Type: Journal    
DOI: 10.1159/000058724     Document Type: Review
Times cited : (47)

References (25)
  • 1
    • 0030825407 scopus 로고    scopus 로고
    • Chemokines
    • 1a Rollins BJ: Chemokines. Blood 1997;90:909-928.
    • (1997) Blood , vol.90 , pp. 909-928
    • Rollins, B.J.1
  • 2
    • 0028316908 scopus 로고
    • Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails
    • Charo IF, Myers SJ, Herman A, Franci C, Connolly AJ, Coughlin SR: Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails. Proc Natl Acad Sci USA 1994;91:2752-2756.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2752-2756
    • Charo, I.F.1    Myers, S.J.2    Herman, A.3    Franci, C.4    Connolly, A.J.5    Coughlin, S.R.6
  • 3
    • 0029005967 scopus 로고
    • Monocyte chemoattractant protein-3, but not monocyte chemoattractant protein-2, is a functional ligand of the human monocyte chemoattractant protein-1 receptor
    • Franci C, Wong LM, Van Damme J, Proost P, Charo IF: Monocyte chemoattractant protein-3, but not monocyte chemoattractant protein-2, is a functional ligand of the human monocyte chemoattractant protein-1 receptor. J Immunol 1995;154:6511-6517.
    • (1995) J Immunol , vol.154 , pp. 6511-6517
    • Franci, C.1    Wong, L.M.2    Van Damme, J.3    Proost, P.4    Charo, I.F.5
  • 4
    • 0031031971 scopus 로고    scopus 로고
    • Murine monocyte chemoattractant protein (MCP)-5: A novel CC chemokine that is a structural and functional homologue of human MCP-1
    • Sarafi MN, Garcia-Zepeda EA, MacLean JA, Charo IF, Luster AD: Murine monocyte chemoattractant protein (MCP)-5: A novel CC chemokine that is a structural and functional homologue of human MCP-1. J Exp Med 1997;185:99-109.
    • (1997) J Exp Med , vol.185 , pp. 99-109
    • Sarafi, M.N.1    Garcia-Zepeda, E.A.2    MacLean, J.A.3    Charo, I.F.4    Luster, A.D.5
  • 6
  • 7
    • 0031013063 scopus 로고    scopus 로고
    • Organization and differential expression of the human monocyte chemoattractant protein 1 receptor gene. Evidence for the role of the carboxyl-terminal tail in receptor trafficking
    • Wong LM, Myers SJ, Tsou CL, Gosling J, Arai H, Charo IF: Organization and differential expression of the human monocyte chemoattractant protein 1 receptor gene. Evidence for the role of the carboxyl-terminal tail in receptor trafficking. J Biol Chem 1997;272:1038-1045.
    • (1997) J Biol Chem , vol.272 , pp. 1038-1045
    • Wong, L.M.1    Myers, S.J.2    Tsou, C.L.3    Gosling, J.4    Arai, H.5    Charo, I.F.6
  • 8
    • 0028970253 scopus 로고
    • Signal transduction and ligand specificity of the human monocyte chemoaatractant protein-1 receptor in transfected embryonic kidney cells
    • Myers SJ, Wong LM, Charo IF: Signal transduction and ligand specificity of the human monocyte chemoaatractant protein-1 receptor in transfected embryonic kidney cells. J Biol Chem 1995;270:5786-5792.
    • (1995) J Biol Chem , vol.270 , pp. 5786-5792
    • Myers, S.J.1    Wong, L.M.2    Charo, I.F.3
  • 9
    • 0029838164 scopus 로고    scopus 로고
    • Differential regulation of G-protein-mediated signaling by chemokine receptors
    • Arai H, Charo IF: Differential regulation of G-protein-mediated signaling by chemokine receptors. J Biol Chem 1996;271:21814-21819.
    • (1996) J Biol Chem , vol.271 , pp. 21814-21819
    • Arai, H.1    Charo, I.F.2
  • 10
    • 0030589242 scopus 로고    scopus 로고
    • Phosphorylation by a G protein-coupled kinase inhibits signaling and promotes internalization of the monocyte chemoattractant protein-1 receptor. Critical role of carboxyl-tail serines/threonines in receptor function
    • Franci C, Gosling J, Tsou CL, Coughlin SR, Charo IF: Phosphorylation by a G protein-coupled kinase inhibits signaling and promotes internalization of the monocyte chemoattractant protein-1 receptor. Critical role of carboxyl-tail serines/threonines in receptor function. J Immunol 1996;157:5606-5612.
    • (1996) J Immunol , vol.157 , pp. 5606-5612
    • Franci, C.1    Gosling, J.2    Tsou, C.L.3    Coughlin, S.R.4    Charo, I.F.5
  • 11
    • 0030754810 scopus 로고    scopus 로고
    • Dissociation of chemotaxis from agonist-induced receptor internalization in a lymphocyte cell line transfected with CCR2B. Evidence that directed migration does not require rapid modulation of signaling at the receptor level
    • Arai H, Monteclaro FS, Tsou CL, Franci C, Charo IF: Dissociation of chemotaxis from agonist-induced receptor internalization in a lymphocyte cell line transfected with CCR2B. Evidence that directed migration does not require rapid modulation of signaling at the receptor level. J Biol Chem 1997;272:25037-25042.
    • (1997) J Biol Chem , vol.272 , pp. 25037-25042
    • Arai, H.1    Monteclaro, F.S.2    Tsou, C.L.3    Franci, C.4    Charo, I.F.5
  • 13
    • 0030604727 scopus 로고    scopus 로고
    • A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors
    • Doranz BJ, Rucker J, Yi Y, Smyth RJ, Samson M, Peiper SC, Parmentier M, Collman RG, Doms RW: A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 1996;85:1149-1158.
    • (1996) Cell , vol.85 , pp. 1149-1158
    • Doranz, B.J.1    Rucker, J.2    Yi, Y.3    Smyth, R.J.4    Samson, M.5    Peiper, S.C.6    Parmentier, M.7    Collman, R.G.8    Doms, R.W.9
  • 14
    • 0030861904 scopus 로고    scopus 로고
    • Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression
    • Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC) AS, O'Brien SJ
    • Smith MW, Dean M, Carrington M, Winkler C, Huttley GA, Lomb DA, Goedert JJ, O'Brien TR, Jacobson LP, Kaslow R, Buchbinder S, Vittinghoff E, Vlahov D, Hoots K, Hilgartner MW, Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC) AS, O'Brien SJ: Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Science 1997;15:959-965.
    • (1997) Science , vol.15 , pp. 959-965
    • Smith, M.W.1    Dean, M.2    Carrington, M.3    Winkler, C.4    Huttley, G.A.5    Lomb, D.A.6    Goedert, J.J.7    O'Brien, T.R.8    Jacobson, L.P.9    Kaslow, R.10    Buchbinder, S.11    Vittinghoff, E.12    Vlahov, D.13    Hoots, K.14    Hilgartner, M.W.15
  • 15
    • 0031851757 scopus 로고    scopus 로고
    • Influence of the CCR2-V64I polymorphism on human immunodeficiency virus type 1 coreceptor activity and on chemokine receptor function of CCR2b, CCR3, CCR5, and CXCR4
    • Lee B, Doranz BJ, Rana S, Yi Y, Mellado M, Frade JM, Martinez-A C, O'Brien SJ, Dean M, Collman RG, Doms RW: Influence of the CCR2-V64I polymorphism on human immunodeficiency virus type 1 coreceptor activity and on chemokine receptor function of CCR2b, CCR3, CCR5, and CXCR4. J Virol 1998;72:7450-7458.
    • (1998) J Virol , vol.72 , pp. 7450-7458
    • Lee, B.1    Doranz, B.J.2    Rana, S.3    Yi, Y.4    Mellado, M.5    Frade, J.M.6    Martinez-A, C.7    O'Brien, S.J.8    Dean, M.9    Collman, R.G.10    Doms, R.W.11
  • 18
    • 0028134907 scopus 로고
    • Cytokine responses during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation. Production of Th1 and Th2 cytokines and relative contribution of tumor necrosis factor
    • Chensue SW, Warmington K, Ruth J, Lincoln P, Kuo MC, Kunkel SL: Cytokine responses during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation. Production of Th1 and Th2 cytokines and relative contribution of tumor necrosis factor. Am J Pathol 1994;145:1105-1113.
    • (1994) Am J Pathol , vol.145 , pp. 1105-1113
    • Chensue, S.W.1    Warmington, K.2    Ruth, J.3    Lincoln, P.4    Kuo, M.C.5    Kunkel, S.L.6
  • 19
    • 0029066095 scopus 로고
    • Cytokine function during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation. Local and regional participation of IFN-γ, IL-10, and TNF
    • Chensus SW, Warmington KS, Ruth JH, Lincoln P, Kunkel SL: Cytokine function during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation. Local and regional participation of IFN-γ, IL-10, and TNF. J Immunol 1995;154:5969-5976.
    • (1995) J Immunol , vol.154 , pp. 5969-5976
    • Chensus, S.W.1    Warmington, K.S.2    Ruth, J.H.3    Lincoln, P.4    Kunkel, S.L.5
  • 20
    • 0030691025 scopus 로고    scopus 로고
    • Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
    • Kuziel WA, Morgan SJ, Dawson TC, Griffin S, Smithies O, Ley K, Maeda N: Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proc Natl Acad Sci USA 1997;94:12053-12058.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12053-12058
    • Kuziel, W.A.1    Morgan, S.J.2    Dawson, T.C.3    Griffin, S.4    Smithies, O.5    Ley, K.6    Maeda, N.7
  • 21
    • 0030699387 scopus 로고    scopus 로고
    • Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor
    • Kurihara T, Warr G, Loy J, Bravo R: Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J Exp Med 1997;186:1757-1762.
    • (1997) J Exp Med , vol.186 , pp. 1757-1762
    • Kurihara, T.1    Warr, G.2    Loy, J.3    Bravo, R.4
  • 22
    • 0026592806 scopus 로고
    • Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
    • Zhang SH, Reddick RL, Piedrahita JA, Maeda N: Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 1992;258:468-471.
    • (1992) Science , vol.258 , pp. 468-471
    • Zhang, S.H.1    Reddick, R.L.2    Piedrahita, J.A.3    Maeda, N.4
  • 23
    • 0027958084 scopus 로고
    • ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree
    • Nakashima Y, Plump AS, Raines EW, Breslow JL, Ross R: ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb 1994;14:133-140.
    • (1994) Arterioscler Thromb , vol.14 , pp. 133-140
    • Nakashima, Y.1    Plump, A.S.2    Raines, E.W.3    Breslow, J.L.4    Ross, R.5
  • 24
    • 0032572719 scopus 로고    scopus 로고
    • Decreased lesion formation in CCR2′ mice reveals a role for chemokines in the initiation of atherosclerosis
    • Boring L, Gosling J, Cleary M, Charo IF: Decreased lesion formation in CCR2′ mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 1998;394:894-897.
    • (1998) Nature , vol.394 , pp. 894-897
    • Boring, L.1    Gosling, J.2    Cleary, M.3    Charo, I.F.4
  • 25
    • 0032134003 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice
    • Gu L, Okada Y, Clinton SK, Gerard C, Sukhova GK, Libby P, Rollins BJ: Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol Cell 1998;2:275-281.
    • (1998) Mol Cell , vol.2 , pp. 275-281
    • Gu, L.1    Okada, Y.2    Clinton, S.K.3    Gerard, C.4    Sukhova, G.K.5    Libby, P.6    Rollins, B.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.