Computational design of second-site suppressor mutations at protein-protein interfaces

Proteins: Structure, Function and Bioinformatics

Volumn 78, Issue 4, 2010, Pages 1055-1065

  Sammond, Deanne W ^a   Eletr, Ziad M ^a   Purbeck, Carrie ^a   Kuhlman, Brian ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Computational protein design; Protein binding specificity; Protein protein interactions; Rosetta molecular modeling software

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; UBIQUITIN PROTEIN LIGASE; PROTEIN;

ARTICLE; BINDING AFFINITY; COMPUTER PROGRAM; EXPERIMENTAL STUDY; HYDROGEN BOND; HYDROPHOBICITY; INTERFACE PRESSURE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; GENE REPRESSION; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE;

COMPUTATIONAL BIOLOGY; HYDROGEN BONDING; HYDROPHOBICITY; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEINS; SUPPRESSION, GENETIC;

EID: 77949327063     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22631     Document Type: Article

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