G2/M checkpoint stringency is a key parameter in the sensitivity of AML cells to genotoxic stress

Oncogene

Volumn 27, Issue 27, 2008, Pages 3811-3820

  Didier, C ^a   Cavelier, C ^a   Quaranta, M ^a   Galcera, M O ^b   Demur, C ^c   Laurent, G ^c   Manenti, S ^c   Ducommun, B ^a,c,d  

^a Institut d'Exploration Fonctionnelle des Genomes   (France)

^b Institut Henri Beaufour   (France)

^c CHU PURPAN   (France)

^d UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

AML; CDC25 phosphatase; Chemoresistance; CHK1 kinase; G2 M Checkpoint

Indexed keywords

7 HYDROXYSTAUROSPORINE; CDC25B PHOSPHATASE; CHECKPOINT KINASE 1; CLASPIN; ETOPOSIDE; PHOSPHATASE; POLO LIKE KINASE 1; PROTEIN; PROTEIN WEE1;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL MATURATION; CELL STRAIN; CELL STRAIN U937; CELL TYPE; CELLULAR STRESS RESPONSE; CHEMOSENSITIVITY; COLONY FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG POTENTIATION; GENOTOXICITY; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSITIVITY ANALYSIS; UPREGULATION;

ANTIGENS, CD; ANTIGENS, CD34; ANTINEOPLASTIC AGENTS; CDC25 PHOSPHATASES; CELL DIVISION; CELL LINE, TUMOR; COLONY-FORMING UNITS ASSAY; G2 PHASE; HUMANS; LEUKEMIA, MYELOID, ACUTE; MITOSIS; NOCODAZOLE; STAUROSPORINE; U937 CELLS;

EID: 45549097605     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1211041     Document Type: Article

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