JAG2 induction in hypoxic tumor cells alters notch signaling and enhances endothelial cell tube formation

Molecular Cancer Research

Volumn 9, Issue 5, 2011, Pages 626-636

  Pietras, Alexander ^a,b   Von Stedingk, Kristoffer ^a   Lindgren, David ^a   Påhlman, Sven ^a,b   Axelson, Håkan ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GENE PRODUCT; HES RELATED 1 PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; JAG2 PROTEIN; NOTCH RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; BURKITT LYMPHOMA; CANCER CELL; CELL HYPOXIA; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM CELL TUBE; GENE EXPRESSION; GENE INDUCTION; GENE TARGETING; GENETIC CORRELATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CARCINOMA; MOUSE; NEUROBLASTOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INDUCTION; TRANSCRIPTION INITIATION; TUMOR VASCULARIZATION;

ANGIOGENIC PROTEINS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BREAST NEOPLASMS; CELL CYCLE PROTEINS; CELL HYPOXIA; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; NEOVASCULARIZATION, PATHOLOGIC; RECEPTOR CROSS-TALK; RECEPTOR, NOTCH1; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79956010254     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-10-0508     Document Type: Article

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