HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 39, 2009, Pages 16805-16810

  Pietras, Alexander ^a   Hansford, Loen M ^b   Johnsson, A Sofie ^a   Bridges, Esther ^a   Sjölund, Jonas ^a   Gisselsson, David ^a   Rehn, Matilda ^a   Beckman, Siv ^a   Noguera, Rosa ^c   Navarro, Samuel ^c   Cammenga, Jörg ^a   Fredlund, Erik ^a   Kaplan, David R ^b   Påhlman, Sven ^a  

^a LUND UNIVERSITY   (Sweden)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Differentiation; HIF 1; Hypoxia; Sympathetic nervous system; Tumor stroma

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 2ALPHA; VASCULOTROPIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; CELL DEATH; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL CREST CELL; NEURAL CREST LIKE NEUROBLASTOMA TUMOR INITIATING CELL; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; STROMA; TUMOR CELL; TUMOR GROWTH; TUMOR XENOGRAFT; VASCULARIZATION; ANIMAL; CELL HYPOXIA; GENETICS; METABOLISM; NEURAL CREST; NUDE MOUSE; TUMOR CELL LINE;

CUCURBITA;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL HYPOXIA; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; HUMANS; MICE; MICE, NUDE; NEURAL CREST; NEUROBLASTOMA; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 70349753257     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904606106     Document Type: Article

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