-
1
-
-
0036850725
-
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein
-
Allen B., Ingram E., Takao M., Smith M.J., Jakes R., Virdee K., Yoshida H., Holzer M., Craxton M., Emson P.C., Atzori C., Migheli A., Crowther R.A., Ghetti B., Spillantini M.G., Goedert M. Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. J. Neurosci. 2002, 22:9340-9351.
-
(2002)
J. Neurosci.
, vol.22
, pp. 9340-9351
-
-
Allen, B.1
Ingram, E.2
Takao, M.3
Smith, M.J.4
Jakes, R.5
Virdee, K.6
Yoshida, H.7
Holzer, M.8
Craxton, M.9
Emson, P.C.10
Atzori, C.11
Migheli, A.12
Crowther, R.A.13
Ghetti, B.14
Spillantini, M.G.15
Goedert, M.16
-
2
-
-
0029999787
-
Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules
-
Alonso A.C., Grundke-Iqbal I., Iqbal K. Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules. Nat. Med. 1996, 2:783-787.
-
(1996)
Nat. Med.
, vol.2
, pp. 783-787
-
-
Alonso, A.C.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
3
-
-
0028227962
-
Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease
-
Alonso A.C., Zaidi T., Grundke-Iqbal I., Iqbal K. Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:5562-5566.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 5562-5566
-
-
Alonso, A.C.1
Zaidi, T.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
4
-
-
0041803006
-
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
-
Andorfer C., Kress Y., Espinoza M., de Silva R., Tucker K.L., Barde Y.A., Duff K., Davies P. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J. Neurochem. 2003, 86:582-590.
-
(2003)
J. Neurochem.
, vol.86
, pp. 582-590
-
-
Andorfer, C.1
Kress, Y.2
Espinoza, M.3
de Silva, R.4
Tucker, K.L.5
Barde, Y.A.6
Duff, K.7
Davies, P.8
-
5
-
-
0035857449
-
Alzheimer's disease as a disorder of mechanisms underlying structural brain self-organization
-
Arendt T. Alzheimer's disease as a disorder of mechanisms underlying structural brain self-organization. Neuroscience 2001, 102:723-765.
-
(2001)
Neuroscience
, vol.102
, pp. 723-765
-
-
Arendt, T.1
-
6
-
-
0018344553
-
Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat
-
Barnes C.A. Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J. Comp. Physiol. Psychol. 1979, 93:74-104.
-
(1979)
J. Comp. Physiol. Psychol.
, vol.93
, pp. 74-104
-
-
Barnes, C.A.1
-
7
-
-
0022365608
-
The distribution of tau in the mammalian central nervous system
-
Binder L.I., Frankfurter A., Rebhun L.I. The distribution of tau in the mammalian central nervous system. J. Cell Biol. 1985, 101:1371-1378.
-
(1985)
J. Cell Biol.
, vol.101
, pp. 1371-1378
-
-
Binder, L.I.1
Frankfurter, A.2
Rebhun, L.I.3
-
8
-
-
0028362458
-
A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
-
Braak E., Braak H., Mandelkow E.M. A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol. (Berl.) 1994, 87:554-567.
-
(1994)
Acta Neuropathol. (Berl.)
, vol.87
, pp. 554-567
-
-
Braak, E.1
Braak, H.2
Mandelkow, E.M.3
-
9
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. (Berl.) 1991, 82:239-259.
-
(1991)
Acta Neuropathol. (Berl.)
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
10
-
-
56049100463
-
A Caenorhabditis elegans model of tau hyperphosphorylation: Induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau
-
Brandt R., Gergou A., Wacker I., Fath T., Hutter H. A Caenorhabditis elegans model of tau hyperphosphorylation: Induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau. Neurobiol. Aging 2009, 30:22-33.
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 22-33
-
-
Brandt, R.1
Gergou, A.2
Wacker, I.3
Fath, T.4
Hutter, H.5
-
11
-
-
0242580519
-
Über einige Erfahrungen mit der Golgi-Methode
-
Bubenaite J. Über einige Erfahrungen mit der Golgi-Methode. Z. Wiss. Mikr. 1929, 46:359-360.
-
(1929)
Z. Wiss. Mikr.
, vol.46
, pp. 359-360
-
-
Bubenaite, J.1
-
12
-
-
27644465539
-
Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM)
-
Canudes A.M., Gutierrez-Cuesta J., Rodriguez M.I., Acuna-Castroviejo D., Sureda F.X., Camins A., Pallas M. Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM). Mech. Ageing Dev. 2005, 126:1300-1304.
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 1300-1304
-
-
Canudes, A.M.1
Gutierrez-Cuesta, J.2
Rodriguez, M.I.3
Acuna-Castroviejo, D.4
Sureda, F.X.5
Camins, A.6
Pallas, M.7
-
13
-
-
3442876436
-
Posttranslational modifications of tau - role in human tauopathies and modeling in transgenic animals
-
Chen F., David D., Ferrari A., Götz J. Posttranslational modifications of tau - role in human tauopathies and modeling in transgenic animals. Curr. Drug Targets 2004, 5:503-515.
-
(2004)
Curr. Drug Targets
, vol.5
, pp. 503-515
-
-
Chen, F.1
David, D.2
Ferrari, A.3
Götz, J.4
-
14
-
-
21244486781
-
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice
-
David D.C., Hauptmann S., Scherping I., Schuessel K., Keil U., Rizzu P., Ravid R., Drose S., Brandt U., Muller W.E., Eckert A., Gotz J. Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. J. Biol. Chem. 2005, 280:23802-23814.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 23802-23814
-
-
David, D.C.1
Hauptmann, S.2
Scherping, I.3
Schuessel, K.4
Keil, U.5
Rizzu, P.6
Ravid, R.7
Drose, S.8
Brandt, U.9
Muller, W.E.10
Eckert, A.11
Gotz, J.12
-
15
-
-
0036841609
-
Tau assembly in inducible transfectants expressing wild-type or FTDP-17 tau
-
DeTure M., Ko L.W., Easson C., Yen S.H. Tau assembly in inducible transfectants expressing wild-type or FTDP-17 tau. Am. J. Pathol. 2002, 161:1711-1722.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 1711-1722
-
-
DeTure, M.1
Ko, L.W.2
Easson, C.3
Yen, S.H.4
-
16
-
-
1842607847
-
-
Development Core Team R A, R Foundation for Statistical Computing, Vienna
-
Development Core Team R A Language and Environment for Statistical Computing 2005, R Foundation for Statistical Computing, Vienna.
-
(2005)
Language and Environment for Statistical Computing
-
-
-
17
-
-
0029813496
-
Topography of brain atrophy during normal aging and Alzheimer's disease
-
Double K.L., Halliday G.M., Kril J.J., Harasty J.A., Cullen K., Brooks W.S., Creasey H., Broe G.A. Topography of brain atrophy during normal aging and Alzheimer's disease. Neurobiol. Aging 1996, 17:513-521.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 513-521
-
-
Double, K.L.1
Halliday, G.M.2
Kril, J.J.3
Harasty, J.A.4
Cullen, K.5
Brooks, W.S.6
Creasey, H.7
Broe, G.A.8
-
18
-
-
0002344794
-
Bootstrap methods: another look at the jackknife
-
Efron B. Bootstrap methods: another look at the jackknife. Ann. Stat. 1979, 7:1-26.
-
(1979)
Ann. Stat.
, vol.7
, pp. 1-26
-
-
Efron, B.1
-
19
-
-
0033792070
-
Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins
-
Eidenmüller J., Fath T., Hellwig A., Reed J., Sontag E., Brandt R. Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins. Biochemistry 2000, 39:13166-13175.
-
(2000)
Biochemistry
, vol.39
, pp. 13166-13175
-
-
Eidenmüller, J.1
Fath, T.2
Hellwig, A.3
Reed, J.4
Sontag, E.5
Brandt, R.6
-
20
-
-
0035425347
-
Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein
-
Eidenmüller J., Fath T., Maas T., Pool M., Sontag E., Brandt R. Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein. Biochem. J. 2001, 357:759-767.
-
(2001)
Biochem. J.
, vol.357
, pp. 759-767
-
-
Eidenmüller, J.1
Fath, T.2
Maas, T.3
Pool, M.4
Sontag, E.5
Brandt, R.6
-
21
-
-
0037111833
-
Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease
-
Fath T., Eidenmüller J., Brandt R. Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease. J. Neurosci. 2002, 22:9733-9741.
-
(2002)
J. Neurosci.
, vol.22
, pp. 9733-9741
-
-
Fath, T.1
Eidenmüller, J.2
Brandt, R.3
-
22
-
-
2842552968
-
Reflex-ontogeny and behavioural development of the mouse
-
Fox W.M. Reflex-ontogeny and behavioural development of the mouse. Anim. Behav. 1965, 13:234-241.
-
(1965)
Anim. Behav.
, vol.13
, pp. 234-241
-
-
Fox, W.M.1
-
23
-
-
0015168149
-
Silver staining of Alzheimer's neurofibrillary changes by means of physical development
-
Gallyas F. Silver staining of Alzheimer's neurofibrillary changes by means of physical development. Acta Morphol. Acad. Sci. Hung. 1971, 19:1-8.
-
(1971)
Acta Morphol. Acad. Sci. Hung.
, vol.19
, pp. 1-8
-
-
Gallyas, F.1
-
24
-
-
84880187096
-
Mice as models: transgenic approaches and Alzheimer's disease
-
Games D., Buttini M., Kobayashi D., Schenk D., Seubert P. Mice as models: transgenic approaches and Alzheimer's disease. J. Alzheimers Dis. 2006, 9:133-149.
-
(2006)
J. Alzheimers Dis.
, vol.9
, pp. 133-149
-
-
Games, D.1
Buttini, M.2
Kobayashi, D.3
Schenk, D.4
Seubert, P.5
-
25
-
-
0028946744
-
Monoclonal antibody AT8 recognizes tau protein phosphorylated at both serine 202 and threonine 205
-
Goedert M., Jakes R., Vanmechelen E. Monoclonal antibody AT8 recognizes tau protein phosphorylated at both serine 202 and threonine 205. Neurosci. Lett. 1995, 189:167-169.
-
(1995)
Neurosci. Lett.
, vol.189
, pp. 167-169
-
-
Goedert, M.1
Jakes, R.2
Vanmechelen, E.3
-
26
-
-
0344653664
-
Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease
-
Gomez-Isla T., Hollister R., West H., Mui S., Growdon J.H., Petersen R.C., Parisi J.E., Hyman B.T. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Ann. Neurol. 1997, 41:17-24.
-
(1997)
Ann. Neurol.
, vol.41
, pp. 17-24
-
-
Gomez-Isla, T.1
Hollister, R.2
West, H.3
Mui, S.4
Growdon, J.H.5
Petersen, R.C.6
Parisi, J.E.7
Hyman, B.T.8
-
27
-
-
0028965635
-
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform
-
Götz J., Probst A., Spillantini M.G., Schafer T., Jakes R., Burki K., Goedert M. Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. EMBO J. 1995, 14:1304-1313.
-
(1995)
EMBO J.
, vol.14
, pp. 1304-1313
-
-
Götz, J.1
Probst, A.2
Spillantini, M.G.3
Schafer, T.4
Jakes, R.5
Burki, K.6
Goedert, M.7
-
28
-
-
3142655729
-
Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy
-
Götz J., Streffer J.R., David D., Schild A., Hoerndli F., Pennanen L., Kurosinski P., Chen F. Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy. Mol. Psychiatry 2004, 9:664-683.
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 664-683
-
-
Götz, J.1
Streffer, J.R.2
David, D.3
Schild, A.4
Hoerndli, F.5
Pennanen, L.6
Kurosinski, P.7
Chen, F.8
-
29
-
-
0031741247
-
New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry
-
Hanger D.P., Betts J.C., Loviny T.L., Blackstock W.P., Anderton B.H. New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry. J. Neurochem. 1998, 71:2465-2476.
-
(1998)
J. Neurochem.
, vol.71
, pp. 2465-2476
-
-
Hanger, D.P.1
Betts, J.C.2
Loviny, T.L.3
Blackstock, W.P.4
Anderton, B.H.5
-
30
-
-
34548191034
-
Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis
-
Hanger D.P., Byers H.L., Wray S., Leung K.Y., Saxton M.J., Seereeram A., Reynolds C.H., Ward M.A., Anderton B.H. Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis. J. Biol. Chem. 2007, 282:23645-23654.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23645-23654
-
-
Hanger, D.P.1
Byers, H.L.2
Wray, S.3
Leung, K.Y.4
Saxton, M.J.5
Seereeram, A.6
Reynolds, C.H.7
Ward, M.A.8
Anderton, B.H.9
-
31
-
-
12344250057
-
Transient and persistent dendritic spines in the neocortex in vivo
-
Holtmaat A.J., Trachtenberg J.T., Wilbrecht L., Shepherd G.M., Zhang X., Knott G.W., Svoboda K. Transient and persistent dendritic spines in the neocortex in vivo. Neuron 2005, 45:279-291.
-
(2005)
Neuron
, vol.45
, pp. 279-291
-
-
Holtmaat, A.J.1
Trachtenberg, J.T.2
Wilbrecht, L.3
Shepherd, G.M.4
Zhang, X.5
Knott, G.W.6
Svoboda, K.7
-
32
-
-
0028090656
-
Abnormally phosphorylated tau protein in Alzheimer's disease: heterogeneity of individual regional distribution and relationship to clinical severity
-
Holzer M., Holzapfel H.P., Zedlick D., Bruckner M.K., Arendt T. Abnormally phosphorylated tau protein in Alzheimer's disease: heterogeneity of individual regional distribution and relationship to clinical severity. Neuroscience 1994, 63:499-516.
-
(1994)
Neuroscience
, vol.63
, pp. 499-516
-
-
Holzer, M.1
Holzapfel, H.P.2
Zedlick, D.3
Bruckner, M.K.4
Arendt, T.5
-
33
-
-
33645520634
-
Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease
-
Jacobsen J.S., Wu C.C., Redwine J.M., Comery T.A., Arias R., Bowlby M., Martone R., Morrison J.H., Pangalos M.N., Reinhart P.H., Bloom F.E. Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:5161-5166.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 5161-5166
-
-
Jacobsen, J.S.1
Wu, C.C.2
Redwine, J.M.3
Comery, T.A.4
Arias, R.5
Bowlby, M.6
Martone, R.7
Morrison, J.H.8
Pangalos, M.N.9
Reinhart, P.H.10
Bloom, F.E.11
-
34
-
-
0028833215
-
Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ
-
Lassmann H., Bancher C., Breitschopf H., Wegiel J., Bobinski M., Jellinger K., Wisniewski H.M. Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ. Acta Neuropathol. (Berl.) 1995, 89:35-41.
-
(1995)
Acta Neuropathol. (Berl.)
, vol.89
, pp. 35-41
-
-
Lassmann, H.1
Bancher, C.2
Breitschopf, H.3
Wegiel, J.4
Bobinski, M.5
Jellinger, K.6
Wisniewski, H.M.7
-
36
-
-
34248222732
-
Inverse and distinct modulation of tau-dependent neurodegeneration by presenilin 1 and amyloid-beta in cultured cortical neurons: evidence that tau phosphorylation is the limiting factor in amyloid-beta-induced cell death
-
Leschik J., Welzel A., Weissmann C., Eckert A., Brandt R. Inverse and distinct modulation of tau-dependent neurodegeneration by presenilin 1 and amyloid-beta in cultured cortical neurons: evidence that tau phosphorylation is the limiting factor in amyloid-beta-induced cell death. J. Neurochem. 2007, 101:1303-1315.
-
(2007)
J. Neurochem.
, vol.101
, pp. 1303-1315
-
-
Leschik, J.1
Welzel, A.2
Weissmann, C.3
Eckert, A.4
Brandt, R.5
-
37
-
-
0028326935
-
Visual cortex in Alzheimer's disease: occurrence of neuronal death and glial proliferation, and correlation with pathological hallmarks
-
Leuba G., Kraftsik R. Visual cortex in Alzheimer's disease: occurrence of neuronal death and glial proliferation, and correlation with pathological hallmarks. Neurobiol. Aging 1994, 15:29-43.
-
(1994)
Neurobiol. Aging
, vol.15
, pp. 29-43
-
-
Leuba, G.1
Kraftsik, R.2
-
38
-
-
3943107461
-
Role of a neuronal small non-messenger RNA: behavioural alterations in BC1 RNA-deleted mice
-
Lewejohann L., Skryabin B.V., Sachser N., Prehn C., Heiduschka P., Thanos S., Jordan U., Dell'Omo G., Vyssotski A.L., Pleskacheva M.G., Lipp H.P., Tiedge H., Brosius J., Prior H. Role of a neuronal small non-messenger RNA: behavioural alterations in BC1 RNA-deleted mice. Behav. Brain Res. 2004, 154:273-289.
-
(2004)
Behav. Brain Res.
, vol.154
, pp. 273-289
-
-
Lewejohann, L.1
Skryabin, B.V.2
Sachser, N.3
Prehn, C.4
Heiduschka, P.5
Thanos, S.6
Jordan, U.7
Dell'Omo, G.8
Vyssotski, A.L.9
Pleskacheva, M.G.10
Lipp, H.P.11
Tiedge, H.12
Brosius, J.13
Prior, H.14
-
39
-
-
0040141570
-
Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments
-
Maas T., Eidenmuller J., Brandt R. Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments. J. Biol. Chem. 2000, 275:15733-15740.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 15733-15740
-
-
Maas, T.1
Eidenmuller, J.2
Brandt, R.3
-
40
-
-
0029066116
-
CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP
-
Mayford M., Wang J., Kandel E.R., O'Dell T.J. CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell 1995, 81:891-904.
-
(1995)
Cell
, vol.81
, pp. 891-904
-
-
Mayford, M.1
Wang, J.2
Kandel, E.R.3
O'Dell, T.J.4
-
41
-
-
33646126924
-
A decade of modeling Alzheimer's disease in transgenic mice
-
McGowan E., Eriksen J., Hutton M. A decade of modeling Alzheimer's disease in transgenic mice. Trends Genet. 2006, 22:281-289.
-
(2006)
Trends Genet.
, vol.22
, pp. 281-289
-
-
McGowan, E.1
Eriksen, J.2
Hutton, M.3
-
42
-
-
0029669963
-
Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A
-
Merrick S.E., Demoise D.C., Lee V.M. Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A. J. Biol. Chem. 1996, 271:5589-5594.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5589-5594
-
-
Merrick, S.E.1
Demoise, D.C.2
Lee, V.M.3
-
43
-
-
0028899714
-
Proline-directed and non-proline-directed phosphorylation of PHF-tau
-
Morishima-Kawashima M., Hasegawa M., Takio K., Suzuki M., Yoshida H., Titani K., Ihara Y. Proline-directed and non-proline-directed phosphorylation of PHF-tau. J. Biol. Chem. 1995, 270:823-829.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 823-829
-
-
Morishima-Kawashima, M.1
Hasegawa, M.2
Takio, K.3
Suzuki, M.4
Yoshida, H.5
Titani, K.6
Ihara, Y.7
-
44
-
-
0033540060
-
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
-
Patrick G.N., Zukerberg L., Nikoloc M., de la Monte S., Dikkes P., Tsai L.H. Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 1999, 402:615-622.
-
(1999)
Nature
, vol.402
, pp. 615-622
-
-
Patrick, G.N.1
Zukerberg, L.2
Nikoloc, M.3
de la Monte, S.4
Dikkes, P.5
Tsai, L.H.6
-
46
-
-
0031814240
-
Are neurons lost from the primate cerebral cortex during normal aging?
-
Peters A., Morrison J.H., Rosene D.L., Hyman B.T. Are neurons lost from the primate cerebral cortex during normal aging?. Cereb. Cortex 1998, 8:295-300.
-
(1998)
Cereb. Cortex
, vol.8
, pp. 295-300
-
-
Peters, A.1
Morrison, J.H.2
Rosene, D.L.3
Hyman, B.T.4
-
47
-
-
33748752882
-
The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation
-
Plattner F., Angelo M., Giese K.P. The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation. J. Biol. Chem. 2006, 281:25457-25465.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 25457-25465
-
-
Plattner, F.1
Angelo, M.2
Giese, K.P.3
-
48
-
-
0346103645
-
Juvenile emotional experience alters synaptic composition in the rodent cortex, hippocampus, and lateral amygdala
-
Poeggel G., Helmeke C., Abraham A., Schwabe T., Friedrich P., Braun K. Juvenile emotional experience alters synaptic composition in the rodent cortex, hippocampus, and lateral amygdala. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:16137-16142.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 16137-16142
-
-
Poeggel, G.1
Helmeke, C.2
Abraham, A.3
Schwabe, T.4
Friedrich, P.5
Braun, K.6
-
49
-
-
34248525053
-
Epitope mapping of mAbs AT8 and Tau5 directed against hyperphosphorylated regions of the human tau protein
-
Porzig R., Singer D., Hoffmann R. Epitope mapping of mAbs AT8 and Tau5 directed against hyperphosphorylated regions of the human tau protein. Biochem. Biophys. Res. Commun. 2007, 358:644-649.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.358
, pp. 644-649
-
-
Porzig, R.1
Singer, D.2
Hoffmann, R.3
-
50
-
-
0001948007
-
Effects of enriched housing environment on the behaviour of young male and female mice in four exploratory tasks
-
Prior H., Sachser N. Effects of enriched housing environment on the behaviour of young male and female mice in four exploratory tasks. J. Exp. Anim. Sci. 1995, 37:57-68.
-
(1995)
J. Exp. Anim. Sci.
, vol.37
, pp. 57-68
-
-
Prior, H.1
Sachser, N.2
-
51
-
-
0035933649
-
SHIRPA, a protocol for behavioral assessment: validation for longitudinal study of neurological dysfunction in mice
-
Rogers D.C., Peters J., Martin J.E., Ball S., Nicholson S.J., Witherden A.S., Hafezparast M., Latcham J., Robinson T.L., Quilter C.A., Fisher E.M. SHIRPA, a protocol for behavioral assessment: validation for longitudinal study of neurological dysfunction in mice. Neurosci. Lett. 2001, 306:89-92.
-
(2001)
Neurosci. Lett.
, vol.306
, pp. 89-92
-
-
Rogers, D.C.1
Peters, J.2
Martin, J.E.3
Ball, S.4
Nicholson, S.J.5
Witherden, A.S.6
Hafezparast, M.7
Latcham, J.8
Robinson, T.L.9
Quilter, C.A.10
Fisher, E.M.11
-
52
-
-
34247611481
-
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment
-
Scheff S.W., Price D.A., Schmitt F.A., DeKosky S.T., Mufson E.J. Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology 2007, 68:1501-1508.
-
(2007)
Neurology
, vol.68
, pp. 1501-1508
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
DeKosky, S.T.4
Mufson, E.J.5
-
53
-
-
0033596946
-
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
-
Schneider A., Biernat J., von Bergen M., Mandelkow E., Mandelkow E.M. Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments. Biochemistry 1999, 38:3549-3558.
-
(1999)
Biochemistry
, vol.38
, pp. 3549-3558
-
-
Schneider, A.1
Biernat, J.2
von Bergen, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
54
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
Selkoe D.J. Alzheimer's disease is a synaptic failure. Science 2002, 298:789-791.
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
55
-
-
33745236883
-
Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices
-
Shahani N., Subramaniam S., Wolf T., Tackenberg C., Brandt R. Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices. J. Neurosci. 2006, 26:6103-6114.
-
(2006)
J. Neurosci.
, vol.26
, pp. 6103-6114
-
-
Shahani, N.1
Subramaniam, S.2
Wolf, T.3
Tackenberg, C.4
Brandt, R.5
-
57
-
-
0029120647
-
Evidence for apoptotic cell death in Alzheimer's disease
-
Smale G., Nichols N.R., Brady D.R., Finch C.E., Horton W.E. Evidence for apoptotic cell death in Alzheimer's disease. Exp. Neurol. 1995, 133:225-230.
-
(1995)
Exp. Neurol.
, vol.133
, pp. 225-230
-
-
Smale, G.1
Nichols, N.R.2
Brady, D.R.3
Finch, C.E.4
Horton, W.E.5
-
58
-
-
0030461275
-
Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A
-
Sontag E., Nunbhakdi-Craig V., Lee G., Bloom G.S., Mumby M.C. Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A. Neuron 1996, 17:1201-1207.
-
(1996)
Neuron
, vol.17
, pp. 1201-1207
-
-
Sontag, E.1
Nunbhakdi-Craig, V.2
Lee, G.3
Bloom, G.S.4
Mumby, M.C.5
-
59
-
-
6344282962
-
Neuronal structure is altered by amyloid plaques
-
Spires T.L., Hyman B.T. Neuronal structure is altered by amyloid plaques. Rev. Neurosci. 2004, 15:267-278.
-
(2004)
Rev. Neurosci.
, vol.15
, pp. 267-278
-
-
Spires, T.L.1
Hyman, B.T.2
-
60
-
-
0032786370
-
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein
-
Spittaels K., Van den Haute C., Van Dorpe J., Bruynseels K., Vandezande K., Laenen I., Geerts H., Mercken M., Sciot R., Van Lommel A., Loos R., Van Leuven F. Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein. Am. J. Pathol. 1999, 155:2153-2165.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 2153-2165
-
-
Spittaels, K.1
Van den Haute, C.2
Van Dorpe, J.3
Bruynseels, K.4
Vandezande, K.5
Laenen, I.6
Geerts, H.7
Mercken, M.8
Sciot, R.9
Van Lommel, A.10
Loos, R.11
Van Leuven, F.12
-
61
-
-
0034731461
-
Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice
-
Spittaels K., Van den Haute C., Van Dorpe J., Geerts H., Mercken M., Bruynseels K., Lasrado R., Vandezande K., Laenen I., Boon T., Van Lint J., Vandenheede J., Moechars D., Loos R., Van Leuven F. Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice. J. Biol. Chem. 2000, 275:41340-41349.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 41340-41349
-
-
Spittaels, K.1
Van den Haute, C.2
Van Dorpe, J.3
Geerts, H.4
Mercken, M.5
Bruynseels, K.6
Lasrado, R.7
Vandezande, K.8
Laenen, I.9
Boon, T.10
Van Lint, J.11
Vandenheede, J.12
Moechars, D.13
Loos, R.14
Van Leuven, F.15
-
62
-
-
0028577208
-
Immunohistochemical evidence for apoptosis in Alzheimer's disease
-
Su J.H., Anderson A.J., Cummings B.J., Cotman C.W. Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport 1994, 5:2529-2533.
-
(1994)
Neuroreport
, vol.5
, pp. 2529-2533
-
-
Su, J.H.1
Anderson, A.J.2
Cummings, B.J.3
Cotman, C.W.4
-
63
-
-
0037108953
-
Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau
-
Tatebayashi Y., Miyasaka T., Chui D.H., Akagi T., Mishima K., Iwasaki K., Fujiwara M., Tanemura K., Murayama M., Ishiguro K., Planel E., Sato S., Hashikawa T., Takashima A. Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:13896-13901.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 13896-13901
-
-
Tatebayashi, Y.1
Miyasaka, T.2
Chui, D.H.3
Akagi, T.4
Mishima, K.5
Iwasaki, K.6
Fujiwara, M.7
Tanemura, K.8
Murayama, M.9
Ishiguro, K.10
Planel, E.11
Sato, S.12
Hashikawa, T.13
Takashima, A.14
-
64
-
-
0020031810
-
A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs)
-
Vallee R.B. A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs). J. Cell Biol. 1982, 92:435-442.
-
(1982)
J. Cell Biol.
, vol.92
, pp. 435-442
-
-
Vallee, R.B.1
-
65
-
-
0000650706
-
The open-field test: a critical review
-
Walsh R.N., Cummins R.A. The open-field test: a critical review. Psychol. Bull. 1976, 83:482-504.
-
(1976)
Psychol. Bull.
, vol.83
, pp. 482-504
-
-
Walsh, R.N.1
Cummins, R.A.2
-
66
-
-
1342322897
-
Assessment of pathological tau proteins in frontotemporal dementias: qualitative and quantitative approaches
-
Zhukareva V., Trojanowski J.Q., Lee V.M. Assessment of pathological tau proteins in frontotemporal dementias: qualitative and quantitative approaches. Am. J. Geriatr. Psychiatry 2004, 12:136-145.
-
(2004)
Am. J. Geriatr. Psychiatry
, vol.12
, pp. 136-145
-
-
Zhukareva, V.1
Trojanowski, J.Q.2
Lee, V.M.3
-
67
-
-
0036790527
-
Biochemical analysis of tau proteins in argyrophilic grain disease, Alzheimer's disease, and Pick's disease: a comparative study
-
Zhukareva V., Shah K., Uryu K., Braak H., Del Tredici K., Sundarraj S., Clark C., Trojanowski J.Q., Lee V.M. Biochemical analysis of tau proteins in argyrophilic grain disease, Alzheimer's disease, and Pick's disease: a comparative study. Am. J. Pathol. 2002, 161:1135-1141.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 1135-1141
-
-
Zhukareva, V.1
Shah, K.2
Uryu, K.3
Braak, H.4
Del Tredici, K.5
Sundarraj, S.6
Clark, C.7
Trojanowski, J.Q.8
Lee, V.M.9
|