-
1
-
-
0034672269
-
Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: A Southwest Oncology Group/Eastern Cooperative Oncology Group Study
-
Slovak ML, Kopecky KJ, Cassileth PA, Harrington DH, Theil KS, Mohamed A, et al. Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study. Blood 2000; 96: 4075-4083.
-
(2000)
Blood
, vol.96
, pp. 4075-4083
-
-
Slovak, M.L.1
Kopecky, K.J.2
Cassileth, P.A.3
Harrington, D.H.4
Theil, K.S.5
Mohamed, A.6
-
2
-
-
0032188805
-
The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties
-
Grimwade D, Walker H, Oliver F, Wheatley K, Harrison C, Harrison G, et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood 1998; 92: 2322-2333.
-
(1998)
Blood
, vol.92
, pp. 2322-2333
-
-
Grimwade, D.1
Walker, H.2
Oliver, F.3
Wheatley, K.4
Harrison, C.5
Harrison, G.6
-
3
-
-
54349092877
-
Monosomal karyotype in acute myeloid leukemia: A better indicator of poor prognosis than a complex karyotype
-
Breems DA, van Putten WL, de Greef GE, Van Zelderen-Bhola SL, Gerssen-Schoorl KB, Mellink CH, et al. Monosomal karyotype in acute myeloid leukemia: a better indicator of poor prognosis than a complex karyotype. J Clin Oncol 2008; 26: 4791-4797.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4791-4797
-
-
Breems, D.A.1
van Putten, W.L.2
de Greef, G.E.3
van Zelderen-Bhola, S.L.4
Gerssen-Schoorl, K.B.5
Mellink, C.H.6
-
4
-
-
33646404606
-
Age and acute myeloid leukemia
-
Appelbaum FR, Gundacker H, Head DR, Slovak ML, Willman CL, Godwin JE, et al. Age and acute myeloid leukemia. Blood 2006; 107: 3481-3485.
-
(2006)
Blood
, vol.107
, pp. 3481-3485
-
-
Appelbaum, F.R.1
Gundacker, H.2
Head, D.R.3
Slovak, M.L.4
Willman, C.L.5
Godwin, J.E.6
-
5
-
-
33745191374
-
Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: Results from Cancer and Leukemia Group B 8461
-
Farag SS, Archer KJ, Mrozek K, Ruppert AS, Carroll AJ, Vardiman JW, et al. Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461. Blood 2006; 108: 63-73.
-
(2006)
Blood
, vol.108
, pp. 63-73
-
-
Farag, S.S.1
Archer, K.J.2
Mrozek, K.3
Ruppert, A.S.4
Carroll, A.J.5
Vardiman, J.W.6
-
6
-
-
0035469883
-
The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): Analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial
-
Grimwade D, Walker H, Harrison G, Oliver F, Chatters S, Harrison CJ, et al. The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial. Blood 2001; 98: 1312-1320.
-
(2001)
Blood
, vol.98
, pp. 1312-1320
-
-
Grimwade, D.1
Walker, H.2
Harrison, G.3
Oliver, F.4
Chatters, S.5
Harrison, C.J.6
-
7
-
-
48749121814
-
Core binding factor acute myeloid leukemia
-
Paschka P. Core binding factor acute myeloid leukemia. Semin Oncol 2008; 35: 410-417.
-
(2008)
Semin Oncol
, vol.35
, pp. 410-417
-
-
Paschka, P.1
-
8
-
-
33748467435
-
Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): A cancer and leukemia group B study
-
Paschka P, Marcucci G, Ruppert AS, Mrozek K, Chen H, Kittles RA, et al. Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a cancer and leukemia group B study. J Clin Oncol 2006; 24: 3904-3911.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3904-3911
-
-
Paschka, P.1
Marcucci, G.2
Ruppert, A.S.3
Mrozek, K.4
Chen, H.5
Kittles, R.A.6
-
9
-
-
3943068350
-
KIT activating mutations: Incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication
-
Beghini A, Ripamonti CB, Cairoli R, Cazzaniga G, Colapietro P, Elice F, et al. KIT activating mutations: incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication. Haematologica 2004; 89: 920-925.
-
(2004)
Haematologica
, vol.89
, pp. 920-925
-
-
Beghini, A.1
Ripamonti, C.B.2
Cairoli, R.3
Cazzaniga, G.4
Colapietro, P.5
Elice, F.6
-
10
-
-
0037114753
-
Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: Results from Cancer and Leukemia Group B (CALGB 8461)
-
Byrd JC, Mrozek K, Dodge RK, Carroll AJ, Edwards CG, Arthur DC, et al. Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). Blood 2002; 100: 4325-4336.
-
(2002)
Blood
, vol.100
, pp. 4325-4336
-
-
Byrd, J.C.1
Mrozek, K.2
Dodge, R.K.3
Carroll, A.J.4
Edwards, C.G.5
Arthur, D.C.6
-
11
-
-
42949142189
-
Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia
-
Schlenk RF, Dohner K, Krauter J, Frohling S, Corbacioglu A, Bullinger L, et al. Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia. N Engl J Med 2008; 358: 1909-1918.
-
(2008)
N Engl J Med
, vol.358
, pp. 1909-1918
-
-
Schlenk, R.F.1
Dohner, K.2
Krauter, J.3
Frohling, S.4
Corbacioglu, A.5
Bullinger, L.6
-
12
-
-
19944427850
-
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
-
Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L, et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med 2005; 352: 254-266.
-
(2005)
N Engl J Med
, vol.352
, pp. 254-266
-
-
Falini, B.1
Mecucci, C.2
Tiacci, E.3
Alcalay, M.4
Rosati, R.5
Pasqualucci, L.6
-
13
-
-
67149119558
-
The favorable impact of CEBPA mutations in patients with acute myeloid leukemia is only observed in the absence of associated cytogenetic abnormalities and FLT3 internal duplication
-
Renneville A, Boissel N, Gachard N, Naguib D, Bastard C, de Botton S, et al. The favorable impact of CEBPA mutations in patients with acute myeloid leukemia is only observed in the absence of associated cytogenetic abnormalities and FLT3 internal duplication. Blood 2009; 113: 5090-5093.
-
(2009)
Blood
, vol.113
, pp. 5090-5093
-
-
Renneville, A.1
Boissel, N.2
Gachard, N.3
Naguib, D.4
Bastard, C.5
de Botton, S.6
-
14
-
-
34548234969
-
High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B Study
-
Marcucci G, Maharry K, Whitman SP, Vukosavljevic T, Paschka P, Langer C, et al. High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B Study. J Clin Oncol 2007; 25: 3337-3343.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3337-3343
-
-
Marcucci, G.1
Maharry, K.2
Whitman, S.P.3
Vukosavljevic, T.4
Paschka, P.5
Langer, C.6
-
15
-
-
70449495051
-
High Id1 expression is associated with poor prognosis in 237 patients with acute myeloid leukemia
-
Tang R, Hirsch P, Fava F, Lapusan S, Marzac C, Teyssandier I, et al. High Id1 expression is associated with poor prognosis in 237 patients with acute myeloid leukemia. Blood 2009; 114: 2993-3000.
-
(2009)
Blood
, vol.114
, pp. 2993-3000
-
-
Tang, R.1
Hirsch, P.2
Fava, F.3
Lapusan, S.4
Marzac, C.5
Teyssandier, I.6
-
16
-
-
53749101166
-
Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study
-
Paschka P, Marcucci G, Ruppert AS, Whitman SP, Mrozek K, Maharry K, et al. Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. J Clin Oncol 2008; 26: 4595-4602.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4595-4602
-
-
Paschka, P.1
Marcucci, G.2
Ruppert, A.S.3
Whitman, S.P.4
Mrozek, K.5
Maharry, K.6
-
17
-
-
66549116716
-
Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia: A study of the German-Austrian AML Study Group
-
Gaidzik VI, Schlenk RF, Moschny S, Becker A, Bullinger L, Corbacioglu A, et al. Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia: a study of the German-Austrian AML Study Group. Blood 2009; 113: 4505-4511.
-
(2009)
Blood
, vol.113
, pp. 4505-4511
-
-
Gaidzik, V.I.1
Schlenk, R.F.2
Moschny, S.3
Becker, A.4
Bullinger, L.5
Corbacioglu, A.6
-
18
-
-
0041440085
-
BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: A Cancer and Leukemia Group B Study
-
Baldus CD, Tanner SM, Ruppert AS, Whitman SP, Archer KJ, Marcucci G, et al. BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study. Blood 2003; 102: 1613-1618.
-
(2003)
Blood
, vol.102
, pp. 1613-1618
-
-
Baldus, C.D.1
Tanner, S.M.2
Ruppert, A.S.3
Whitman, S.P.4
Archer, K.J.5
Marcucci, G.6
-
19
-
-
67650312343
-
Prognostic importance of MN1 transcript levels, and biologic insights from MN1-associated gene and microRNA expression signatures in cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B Study
-
Langer C, Marcucci G, Holland KB, Radmacher MD, Maharry K, Paschka P, et al. Prognostic importance of MN1 transcript levels, and biologic insights from MN1-associated gene and microRNA expression signatures in cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B Study. J Clin Oncol 2009; 27: 3198-3204.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3198-3204
-
-
Langer, C.1
Marcucci, G.2
Holland, K.B.3
Radmacher, M.D.4
Maharry, K.5
Paschka, P.6
-
20
-
-
42949122111
-
High EVI1 levels predict adverse outcome in acute myeloid leukemia: Prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated
-
Lugthart S, van Drunen E, van Norden Y, van HA, Erpelinck CA, Valk PJ, et al. High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated. Blood 2008; 111: 4329-4337.
-
(2008)
Blood
, vol.111
, pp. 4329-4337
-
-
Lugthart, S.1
van Drunen, E.2
van Norden, Y.3
Van, H.A.4
Erpelinck, C.A.5
Valk, P.J.6
-
21
-
-
16544369516
-
Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia
-
Bullinger L, Dohner K, Bair E, Frohling S, Schlenk RF, Tibshirani R, et al. Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. N Engl J Med 2004; 350: 1605-1616.
-
(2004)
N Engl J Med
, vol.350
, pp. 1605-1616
-
-
Bullinger, L.1
Dohner, K.2
Bair, E.3
Frohling, S.4
Schlenk, R.F.5
Tibshirani, R.6
-
22
-
-
58849167390
-
A decade of genome-wide gene expression profiling in acute myeloid leukemia: Flashback and prospects
-
Wouters BJ, Lowenberg B, Delwel R. A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects. Blood 2009; 113: 291-298.
-
(2009)
Blood
, vol.113
, pp. 291-298
-
-
Wouters, B.J.1
Lowenberg, B.2
Delwel, R.3
-
23
-
-
33747420007
-
Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: A Cancer and Leukemia Group B study
-
Radmacher MD, Marcucci G, Ruppert AS, Mrozek K, Whitman SP, Vardiman JW, et al. Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study. Blood 2006; 108: 1677-1683.
-
(2006)
Blood
, vol.108
, pp. 1677-1683
-
-
Radmacher, M.D.1
Marcucci, G.2
Ruppert, A.S.3
Mrozek, K.4
Whitman, S.P.5
Vardiman, J.W.6
-
24
-
-
42949083345
-
MicroRNA expression in cytogenetically normal acute myeloid leukemia
-
Marcucci G, Radmacher MD, Maharry K, Mrozek K, Ruppert AS, Paschka P, et al. MicroRNA expression in cytogenetically normal acute myeloid leukemia. N Engl J Med 2008; 358: 1919-1928.
-
(2008)
N Engl J Med
, vol.358
, pp. 1919-1928
-
-
Marcucci, G.1
Radmacher, M.D.2
Maharry, K.3
Mrozek, K.4
Ruppert, A.S.5
Paschka, P.6
-
25
-
-
74049146227
-
Minimal residual disease quantitation in acute myeloid leukemia
-
Shook D, Coustan-Smith E, Ribeiro RC, Rubnitz JE, Campana D. Minimal residual disease quantitation in acute myeloid leukemia. Clin Lymphoma Myeloma 2009; 9 Suppl 3: s281-s285.
-
(2009)
Clin Lymphoma Myeloma
, vol.9
, Issue.SUPPL. 3
-
-
Shook, D.1
Coustan-Smith, E.2
Ribeiro, R.C.3
Rubnitz, J.E.4
Campana, D.5
-
26
-
-
0025719792
-
A comparative study of two different doses of cytarabine for acute myeloid leukemia: A phase III trial of Cancer and Leukemia Group B
-
Dillman RO, Davis RB, Green MR, Weiss RB, Gottlieb AJ, Caplan S, et al. A comparative study of two different doses of cytarabine for acute myeloid leukemia: a phase III trial of Cancer and Leukemia Group B. Blood 1991; 78: 2520-2526.
-
(1991)
Blood
, vol.78
, pp. 2520-2526
-
-
Dillman, R.O.1
Davis, R.B.2
Green, M.R.3
Weiss, R.B.4
Gottlieb, A.J.5
Caplan, S.6
-
27
-
-
33751267902
-
Acute myeloid leukaemia
-
Estey E, Dohner H. Acute myeloid leukaemia. Lancet 2006; 368: 1894-1907.
-
(2006)
Lancet
, vol.368
, pp. 1894-1907
-
-
Estey, E.1
Dohner, H.2
-
28
-
-
23644455476
-
Drug therapy for acute myeloid leukemia
-
Tallman MS, Gilliland DG, Rowe JM. Drug therapy for acute myeloid leukemia. Blood 2005; 106: 1154-1163.
-
(2005)
Blood
, vol.106
, pp. 1154-1163
-
-
Tallman, M.S.1
Gilliland, D.G.2
Rowe, J.M.3
-
29
-
-
0026650021
-
A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: A Southeastern Cancer Study Group Study
-
Vogler WR, Velez-Garcia E, Weiner RS, Flaum MA, Bartolucci AA, Omura GA, et al. A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: a Southeastern Cancer Study Group Study. J Clin Oncol 1992; 10: 1103-1111.
-
(1992)
J Clin Oncol
, vol.10
, pp. 1103-1111
-
-
Vogler, W.R.1
Velez-Garcia, E.2
Weiner, R.S.3
Flaum, M.A.4
Bartolucci, A.A.5
Omura, G.A.6
-
30
-
-
0042967809
-
Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia
-
Lowenberg B, van Putten W, Theobald M, Gmur J, Verdonck L, Sonneveld P, et al. Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia. N Engl J Med 2003; 349: 743-752.
-
(2003)
N Engl J Med
, vol.349
, pp. 743-752
-
-
Lowenberg, B.1
van Putten, W.2
Theobald, M.3
Gmur, J.4
Verdonck, L.5
Sonneveld, P.6
-
31
-
-
0030895252
-
Randomized comparison of DAT versus ADE as induction chemotherapy in children and younger adults with acute myeloid leukemia. Results of the Medical Research Council's 10th AML trial (MRC AML10). Adult and Childhood Leukaemia Working Parties of the Medical Research Council
-
Hann IM, Stevens RF, Goldstone AH, Rees JK, Wheatley K, Gray RG, et al. Randomized comparison of DAT versus ADE as induction chemotherapy in children and younger adults with acute myeloid leukemia. Results of the Medical Research Council's 10th AML trial (MRC AML10). Adult and Childhood Leukaemia Working Parties of the Medical Research Council. Blood 1997; 89: 2311-2318.
-
(1997)
Blood
, vol.89
, pp. 2311-2318
-
-
Hann, I.M.1
Stevens, R.F.2
Goldstone, A.H.3
Rees, J.K.4
Wheatley, K.5
Gray, R.G.6
-
32
-
-
9044228414
-
A randomized study of high-dose cytarabine in induction in acute myeloid leukemia
-
Bishop JF, Matthews JP, Young GA, Szer J, Gillett A, Joshua D, et al. A randomized study of high-dose cytarabine in induction in acute myeloid leukemia. Blood 1996; 87: 1710-1717.
-
(1996)
Blood
, vol.87
, pp. 1710-1717
-
-
Bishop, J.F.1
Matthews, J.P.2
Young, G.A.3
Szer, J.4
Gillett, A.5
Joshua, D.6
-
33
-
-
70349451999
-
High-dose daunorubicin in older patients with acute myeloid leukemia
-
Lowenberg B, Ossenkoppele GJ, van Putten W, Schouten HC, Graux C, Ferrant A, et al. High-dose daunorubicin in older patients with acute myeloid leukemia. N Engl J Med 2009; 361: 1235-1248.
-
(2009)
N Engl J Med
, vol.361
, pp. 1235-1248
-
-
Lowenberg, B.1
Ossenkoppele, G.J.2
van Putten, W.3
Schouten, H.C.4
Graux, C.5
Ferrant, A.6
-
34
-
-
35048820182
-
Impact of remission induction chemotherapy on survival in older adults with acute myeloid leukemia
-
Baz R, Rodriguez C, Fu AZ, Jawde RA, Kalaycio M, Advani A, et al. Impact of remission induction chemotherapy on survival in older adults with acute myeloid leukemia. Cancer 2007; 110: 1752-1759.
-
(2007)
Cancer
, vol.110
, pp. 1752-1759
-
-
Baz, R.1
Rodriguez, C.2
Fu, A.Z.3
Jawde, R.A.4
Kalaycio, M.5
Advani, A.6
-
35
-
-
66149148673
-
Age and acute myeloid leukemia: Real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry
-
Juliusson G, Antunovic P, Derolf A, Lehmann S, Mollgard L, Stockelberg D, et al. Age and acute myeloid leukemia: real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry. Blood 2009; 113: 4179-4187.
-
(2009)
Blood
, vol.113
, pp. 4179-4187
-
-
Juliusson, G.1
Antunovic, P.2
Derolf, A.3
Lehmann, S.4
Mollgard, L.5
Stockelberg, D.6
-
36
-
-
0025280579
-
Postremission chemotherapy for adults with acute myelogenous leukemia: Improved survival with high-dose cytarabine and daunorubicin consolidation treatment
-
Champlin R, Gajewski J, Nimer S, Vollset S, Landaw E, Winston D, et al. Postremission chemotherapy for adults with acute myelogenous leukemia: improved survival with high-dose cytarabine and daunorubicin consolidation treatment. J Clin Oncol 1990; 8: 1199-1206.
-
(1990)
J Clin Oncol
, vol.8
, pp. 1199-1206
-
-
Champlin, R.1
Gajewski, J.2
Nimer, S.3
Vollset, S.4
Landaw, E.5
Winston, D.6
-
37
-
-
17544388046
-
Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype
-
Bloomfield CD, Lawrence D, Byrd JC, Carroll A, Pettenati MJ, Tantravahi R, et al. Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype. Cancer Res 1998; 58: 4173-4179.
-
(1998)
Cancer Res
, vol.58
, pp. 4173-4179
-
-
Bloomfield, C.D.1
Lawrence, D.2
Byrd, J.C.3
Carroll, A.4
Pettenati, M.J.5
Tantravahi, R.6
-
38
-
-
0027941369
-
Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B
-
Mayer RJ, Davis RB, Schiffer CA, Berg DT, Powell BL, Schulman P, et al. Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B. N Engl J Med 1994; 331: 896-903.
-
(1994)
N Engl J Med
, vol.331
, pp. 896-903
-
-
Mayer, R.J.1
Davis, R.B.2
Schiffer, C.A.3
Berg, D.T.4
Powell, B.L.5
Schulman, P.6
-
39
-
-
0037377715
-
Comparison of allogeneic stem cell transplantation, high-dose cytarabine, and autologous peripheral stem cell transplantation as postremission treatment in patients with de novo acute myelogenous leukemia
-
Tsimberidou AM, Stavroyianni N, Viniou N, Papaioannou M, Tiniakou M, Marinakis T, et al. Comparison of allogeneic stem cell transplantation, high-dose cytarabine, and autologous peripheral stem cell transplantation as postremission treatment in patients with de novo acute myelogenous leukemia. Cancer 2003; 97: 1721-1731.
-
(2003)
Cancer
, vol.97
, pp. 1721-1731
-
-
Tsimberidou, A.M.1
Stavroyianni, N.2
Viniou, N.3
Papaioannou, M.4
Tiniakou, M.5
Marinakis, T.6
-
40
-
-
33745003472
-
Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia
-
Buchner T, Berdel WE, Schoch C, Haferlach T, Serve HL, Kienast J, et al. Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia. J Clin Oncol 2006; 24: 2480-2489.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2480-2489
-
-
Buchner, T.1
Berdel, W.E.2
Schoch, C.3
Haferlach, T.4
Serve, H.L.5
Kienast, J.6
-
41
-
-
4644288302
-
Individual patient data-based meta-analysis of patients aged 16 to 60 years with core binding factor acute myeloid leukemia: A survey of the German Acute Myeloid Leukemia Intergroup
-
Schlenk RF, Benner A, Krauter J, Buchner T, Sauerland C, Ehninger G, et al. Individual patient data-based meta-analysis of patients aged 16 to 60 years with core binding factor acute myeloid leukemia: a survey of the German Acute Myeloid Leukemia Intergroup. J Clin Oncol 2004; 22: 3741-3750.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3741-3750
-
-
Schlenk, R.F.1
Benner, A.2
Krauter, J.3
Buchner, T.4
Sauerland, C.5
Ehninger, G.6
-
42
-
-
0032492441
-
Randomised comparison of addition of autologous bone-marrow transplantation to intensive chemotherapy for acute myeloid leukaemia in first remission: Results of MRC AML 10 trial. UK Medical Research Council Adult and Children's Leukaemia Working Parties
-
Burnett AK, Goldstone AH, Stevens RM, Hann IM, Rees JK, Gray RG, et al. Randomised comparison of addition of autologous bone-marrow transplantation to intensive chemotherapy for acute myeloid leukaemia in first remission: results of MRC AML 10 trial. UK Medical Research Council Adult and Children's Leukaemia Working Parties. Lancet 1998; 351: 700-708.
-
(1998)
Lancet
, vol.351
, pp. 700-708
-
-
Burnett, A.K.1
Goldstone, A.H.2
Stevens, R.M.3
Hann, I.M.4
Rees, J.K.5
Gray, R.G.6
-
43
-
-
0028889993
-
Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) Leukemia Cooperative Groups
-
Zittoun RA, Mandelli F, Willemze R, de Witte T, Labar B, Resegotti L, et al. Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) Leukemia Cooperative Groups. N Engl J Med 1995; 332: 217-223.
-
(1995)
N Engl J Med
, vol.332
, pp. 217-223
-
-
Zittoun, R.A.1
Mandelli, F.2
Willemze, R.3
de Witte, T.4
Labar, B.5
Resegotti, L.6
-
44
-
-
0842302519
-
Consolidation therapy with autologous bone marrow transplantation in adults with acute myeloid leukemia: A meta-analysis
-
Nathan PC, Sung L, Crump M, Beyene J. Consolidation therapy with autologous bone marrow transplantation in adults with acute myeloid leukemia: a meta-analysis. J Natl Cancer Inst 2004; 96: 38-45.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 38-45
-
-
Nathan, P.C.1
Sung, L.2
Crump, M.3
Beyene, J.4
-
45
-
-
65549090436
-
Acute myelogenous leukemia
-
Shipley JL, Butera JN. Acute myelogenous leukemia. Exp Hematol 2009; 37: 649-658.
-
(2009)
Exp Hematol
, vol.37
, pp. 649-658
-
-
Shipley, J.L.1
Butera, J.N.2
-
46
-
-
67049164836
-
Allogeneic stem cell transplantation for acute myeloid leukemia in first complete remission: Systematic review and meta-analysis of prospective clinical trials
-
Koreth J, Schlenk R, Kopecky KJ, Honda S, Sierra J, Djulbegovic BJ, et al. Allogeneic stem cell transplantation for acute myeloid leukemia in first complete remission: systematic review and meta-analysis of prospective clinical trials. JAMA 2009; 301: 2349-2361.
-
(2009)
JAMA
, vol.301
, pp. 2349-2361
-
-
Koreth, J.1
Schlenk, R.2
Kopecky, K.J.3
Honda, S.4
Sierra, J.5
Djulbegovic, B.J.6
-
47
-
-
34247325560
-
Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: Benefits for whom?
-
Cornelissen JJ, van Putten WL, Verdonck LF, Theobald M, Jacky E, Daenen SM, et al. Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: benefits for whom? Blood 2007; 109: 3658-3666.
-
(2007)
Blood
, vol.109
, pp. 3658-3666
-
-
Cornelissen, J.J.1
van Putten, W.L.2
Verdonck, L.F.3
Theobald, M.4
Jacky, E.5
Daenen, S.M.6
-
50
-
-
0026668478
-
Varying intensity of postremission therapy in acute myeloid leukemia
-
Cassileth PA, Lynch E, Hines JD, Oken MM, Mazza JJ, Bennett JM, et al. Varying intensity of postremission therapy in acute myeloid leukemia. Blood 1992; 79: 1924-1930.
-
(1992)
Blood
, vol.79
, pp. 1924-1930
-
-
Cassileth, P.A.1
Lynch, E.2
Hines, J.D.3
Oken, M.M.4
Mazza, J.J.5
Bennett, J.M.6
-
51
-
-
1542753653
-
6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): A randomized trial of the German AML Cooperative Group
-
Buchner T, Hiddemann W, Berdel WE, Wormann B, Schoch C, Fonatsch C, et al. 6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): a randomized trial of the German AML Cooperative Group. J Clin Oncol 2003; 21: 4496-4504.
-
(2003)
J Clin Oncol
, vol.21
, pp. 4496-4504
-
-
Buchner, T.1
Hiddemann, W.2
Berdel, W.E.3
Wormann, B.4
Schoch, C.5
Fonatsch, C.6
-
52
-
-
45549083917
-
Treatment of relapsed acute myeloid leukaemia
-
Kell J. Treatment of relapsed acute myeloid leukaemia. Rev Recent Clin Trials 2006; 1: 103-111.
-
(2006)
Rev Recent Clin Trials
, vol.1
, pp. 103-111
-
-
Kell, J.1
-
53
-
-
20244361887
-
Prognostic index for adult patients with acute myeloid leukemia in first relapse
-
Breems DA, van Putten WL, Huijgens PC, Ossenkoppele GJ, Verhoef GE, Verdonck LF, et al. Prognostic index for adult patients with acute myeloid leukemia in first relapse. J Clin Oncol 2005; 23: 1969-1978.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1969-1978
-
-
Breems, D.A.1
van Putten, W.L.2
Huijgens, P.C.3
Ossenkoppele, G.J.4
Verhoef, G.E.5
Verdonck, L.F.6
-
54
-
-
17144416476
-
Biology and management of relapsed acute myeloid leukaemia
-
Craddock C, Tauro S, Moss P, Grimwade D. Biology and management of relapsed acute myeloid leukaemia. Br J Haematol 2005; 129: 18-34.
-
(2005)
Br J Haematol
, vol.129
, pp. 18-34
-
-
Craddock, C.1
Tauro, S.2
Moss, P.3
Grimwade, D.4
-
55
-
-
0034009065
-
Treatment of relapsed and refractory acute myelogenous leukemia
-
Estey EH. Treatment of relapsed and refractory acute myelogenous leukemia. Leukemia 2000; 14: 476-479.
-
(2000)
Leukemia
, vol.14
, pp. 476-479
-
-
Estey, E.H.1
-
56
-
-
0033975925
-
Multivariate analysis of prognostic factors in patients with refractory and relapsed acute myeloid leukemia undergoing sequential high-dose cytosine arabinoside and mitoxantrone (S-HAM) salvage therapy: Relevance of cytogenetic abnormalities
-
Kern W, Schoch C, Haferlach T, Braess J, Unterhalt M, Ormann B, et al. Multivariate analysis of prognostic factors in patients with refractory and relapsed acute myeloid leukemia undergoing sequential high-dose cytosine arabinoside and mitoxantrone (S-HAM) salvage therapy: relevance of cytogenetic abnormalities. Leukemia 2000; 14: 226-231.
-
(2000)
Leukemia
, vol.14
, pp. 226-231
-
-
Kern, W.1
Schoch, C.2
Haferlach, T.3
Braess, J.4
Unterhalt, M.5
Ormann, B.6
-
57
-
-
0032809362
-
A phase III comparison of high dose ARA-C (HIDAC) versus HIDAC plus mitoxantrone in the treatment of first relapsed or refractory acute myeloid leukemia Southwest Oncology Group Study
-
Karanes C, Kopecky KJ, Head DR, Grever MR, Hynes HE, Kraut EH, et al. A phase III comparison of high dose ARA-C (HIDAC) versus HIDAC plus mitoxantrone in the treatment of first relapsed or refractory acute myeloid leukemia Southwest Oncology Group Study. Leuk Res 1999; 23: 787-794.
-
(1999)
Leuk Res
, vol.23
, pp. 787-794
-
-
Karanes, C.1
Kopecky, K.J.2
Head, D.R.3
Grever, M.R.4
Hynes, H.E.5
Kraut, E.H.6
-
58
-
-
0038518581
-
Allogeneic stem-cell transplantation from related and unrelated donors in older patients with myeloid leukemia
-
Bertz H, Potthoff K, Finke J. Allogeneic stem-cell transplantation from related and unrelated donors in older patients with myeloid leukemia. J Clin Oncol 2003; 21: 1480-1484.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1480-1484
-
-
Bertz, H.1
Potthoff, K.2
Finke, J.3
-
59
-
-
33847206021
-
The role of autologous transplantation for acute myeloid leukemia in first and second remission
-
Linker C. The role of autologous transplantation for acute myeloid leukemia in first and second remission. Best Pract Res Clin Haematol 2007; 20: 77-84.
-
(2007)
Best Pract Res Clin Haematol
, vol.20
, pp. 77-84
-
-
Linker, C.1
-
60
-
-
33845260304
-
Long-term outcomes of myeloablation and autologous transplantation of relapsed acute myeloid leukemia in second remission: A British Society of Blood and Marrow Transplantation registry study
-
Chantry AD, Snowden JA, Craddock C, Peggs K, Roddie C, Craig JI, et al. Long-term outcomes of myeloablation and autologous transplantation of relapsed acute myeloid leukemia in second remission: a British Society of Blood and Marrow Transplantation registry study. Biol Blood Marrow Transplant 2006; 12: 1310-1317.
-
(2006)
Biol Blood Marrow Transplant
, vol.12
, pp. 1310-1317
-
-
Chantry, A.D.1
Snowden, J.A.2
Craddock, C.3
Peggs, K.4
Roddie, C.5
Craig, J.I.6
-
61
-
-
0021345113
-
Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia
-
Larson RA, Kondo K, Vardiman JW, Butler AE, Golomb HM, Rowley JD. Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia. Am J Med 1984; 76: 827-841.
-
(1984)
Am J Med
, vol.76
, pp. 827-841
-
-
Larson, R.A.1
Kondo, K.2
Vardiman, J.W.3
Butler, A.E.4
Golomb, H.M.5
Rowley, J.D.6
-
62
-
-
0025875679
-
The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
-
de The H, Lavau C, Marchio A, Chomienne C, Degos L, Dejean A. The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell 1991; 66: 675-684.
-
(1991)
Cell
, vol.66
, pp. 675-684
-
-
de The, H.1
Lavau, C.2
Marchio, A.3
Chomienne, C.4
Degos, L.5
Dejean, A.6
-
63
-
-
0034663162
-
Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: A joint study of the PETHEMA and GIMEMA cooperative groups
-
Sanz MA, Lo Coco F, Martin G, Avvisati G, Rayon C, Barbui T, et al. Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: a joint study of the PETHEMA and GIMEMA cooperative groups. Blood 2000; 96: 1247-1253.
-
(2000)
Blood
, vol.96
, pp. 1247-1253
-
-
Sanz, M.A.1
Lo Coco, F.2
Martin, G.3
Avvisati, G.4
Rayon, C.5
Barbui, T.6
-
64
-
-
43549105926
-
Causes and prognostic factors of remission induction failure in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and idarubicin
-
de la Serna J, Montesinos P, Vellenga E, Rayon C, Parody R, Leon A, et al. Causes and prognostic factors of remission induction failure in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and idarubicin. Blood 2008; 111: 3395-3402.
-
(2008)
Blood
, vol.111
, pp. 3395-3402
-
-
de la Serna, J.1
Montesinos, P.2
Vellenga, E.3
Rayon, C.4
Parody, R.5
Leon, A.6
-
65
-
-
54049087434
-
Risk-adapted treatment of acute promyelocytic leukemia with all-trans retinoic acid and anthracycline monochemotherapy: Long-term outcome of the LPA 99 multicenter study by the PETHEMA Group
-
Sanz MA, Montesinos P, Vellenga E, Rayon C, de la Serna J, Parody R, et al. Risk-adapted treatment of acute promyelocytic leukemia with all-trans retinoic acid and anthracycline monochemotherapy: long-term outcome of the LPA 99 multicenter study by the PETHEMA Group. Blood 2008; 112: 3130-3134.
-
(2008)
Blood
, vol.112
, pp. 3130-3134
-
-
Sanz, M.A.1
Montesinos, P.2
Vellenga, E.3
Rayon, C.4
de la Serna, J.5
Parody, R.6
-
66
-
-
9444297295
-
All-trans retinoic acid and anthracycline monochemotherapy for the treatment of elderly patients with acute promyelocytic leukemia
-
Sanz MA, Vellenga E, Rayon C, Diaz-Mediavilla J, Rivas C, Amutio E, et al. All-trans retinoic acid and anthracycline monochemotherapy for the treatment of elderly patients with acute promyelocytic leukemia. Blood 2004; 104: 3490-3493.
-
(2004)
Blood
, vol.104
, pp. 3490-3493
-
-
Sanz, M.A.1
Vellenga, E.2
Rayon, C.3
Diaz-Mediavilla, J.4
Rivas, C.5
Amutio, E.6
-
67
-
-
0036464594
-
Acute promyelocytic leukemia: Evolving therapeutic strategies
-
Tallman MS, Nabhan C, Feusner JH, Rowe JM. Acute promyelocytic leukemia: evolving therapeutic strategies. Blood 2002; 99: 759-767.
-
(2002)
Blood
, vol.99
, pp. 759-767
-
-
Tallman, M.S.1
Nabhan, C.2
Feusner, J.H.3
Rowe, J.M.4
-
68
-
-
0033566639
-
A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. The European APL Group
-
Fenaux P, Chastang C, Chevret S, Sanz M, Dombret H, Archimbaud E, et al. A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. The European APL Group. Blood 1999; 94: 1192-1200.
-
(1999)
Blood
, vol.94
, pp. 1192-1200
-
-
Fenaux, P.1
Chastang, C.2
Chevret, S.3
Sanz, M.4
Dombret, H.5
Archimbaud, E.6
-
69
-
-
38949092914
-
Treatment of newly diagnosed acute promyelocytic leukemia (APL): A comparison of French-Belgian-Swiss and PETHEMA results
-
Ades L, Sanz MA, Chevret S, Montesinos P, Chevallier P, Raffoux E, et al. Treatment of newly diagnosed acute promyelocytic leukemia (APL): a comparison of French-Belgian-Swiss and PETHEMA results. Blood 2008; 111: 1078-1084.
-
(2008)
Blood
, vol.111
, pp. 1078-1084
-
-
Ades, L.1
Sanz, M.A.2
Chevret, S.3
Montesinos, P.4
Chevallier, P.5
Raffoux, E.6
-
70
-
-
62549083523
-
Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia
-
Hu J, Liu YF, Wu CF, Xu F, Shen ZX, Zhu YM, et al. Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia. Proc Natl Acad Sci U S A 2009; 106: 3342-3347.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3342-3347
-
-
Hu, J.1
Liu, Y.F.2
Wu, C.F.3
Xu, F.4
Shen, Z.X.5
Zhu, Y.M.6
-
71
-
-
59149089411
-
Effective treatment of acute promyelocytic leukemia with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin
-
Ravandi F, Estey E, Jones D, Faderl S, O'Brien S, Fiorentino J, et al. Effective treatment of acute promyelocytic leukemia with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin. J Clin Oncol 2009; 27: 504-510.
-
(2009)
J Clin Oncol
, vol.27
, pp. 504-510
-
-
Ravandi, F.1
Estey, E.2
Jones, D.3
Faderl, S.4
O'Brien, S.5
Fiorentino, J.6
-
72
-
-
77950347319
-
Single-agent arsenic trioxide in the treatment of children with newly diagnosed acute promyelocytic leukemia
-
Zhou J, Zhang Y, Li J, Li X, Hou J, Zhao Y, et al. Single-agent arsenic trioxide in the treatment of children with newly diagnosed acute promyelocytic leukemia. Blood 2010; 115: 1697-1702.
-
(2010)
Blood
, vol.115
, pp. 1697-1702
-
-
Zhou, J.1
Zhang, Y.2
Li, J.3
Li, X.4
Hou, J.5
Zhao, Y.6
-
73
-
-
17044401059
-
Tricks of the trade for the appropriate management of newly diagnosed acute promyelocytic leukemia
-
Sanz MA, Tallman MS, Lo-Coco F. Tricks of the trade for the appropriate management of newly diagnosed acute promyelocytic leukemia. Blood 2005; 105: 3019-3025.
-
(2005)
Blood
, vol.105
, pp. 3019-3025
-
-
Sanz, M.A.1
Tallman, M.S.2
Lo-Coco, F.3
-
74
-
-
10744220024
-
Risk-adapted treatment of acute promyelocytic leukemia with all-trans-retinoic acid and anthracycline monochemotherapy: A multicenter study by the PETHEMA group
-
Sanz MA, Martin G, Gonzalez M, Leon A, Rayon C, Rivas C, et al. Risk-adapted treatment of acute promyelocytic leukemia with all-trans-retinoic acid and anthracycline monochemotherapy: a multicenter study by the PETHEMA group. Blood 2004; 103: 1237-1243.
-
(2004)
Blood
, vol.103
, pp. 1237-1243
-
-
Sanz, M.A.1
Martin, G.2
Gonzalez, M.3
Leon, A.4
Rayon, C.5
Rivas, C.6
-
75
-
-
48749083640
-
Acute promyelocytic leukemia: Recent advances in diagnosis and management
-
Lo-Coco F, Ammatuna E, Montesinos P, Sanz MA. Acute promyelocytic leukemia: recent advances in diagnosis and management. Semin Oncol 2008; 35: 401-409.
-
(2008)
Semin Oncol
, vol.35
, pp. 401-409
-
-
Lo-Coco, F.1
Ammatuna, E.2
Montesinos, P.3
Sanz, M.A.4
-
77
-
-
33645498328
-
Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: Durable remissions with minimal toxicity
-
Mathews V, George B, Lakshmi KM, Viswabandya A, Bajel A, Balasubramanian P, et al. Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity. Blood 2006; 107: 2627-2632.
-
(2006)
Blood
, vol.107
, pp. 2627-2632
-
-
Mathews, V.1
George, B.2
Lakshmi, K.M.3
Viswabandya, A.4
Bajel, A.5
Balasubramanian, P.6
-
78
-
-
61949441174
-
Management of acute promyelocytic leukemia: Recommendations from an expert panel on behalf of the European LeukemiaNet
-
Sanz MA, Grimwade D, Tallman MS, Lowenberg B, Fenaux P, Estey EH, et al. Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet. Blood 2009; 113: 1875-1891.
-
(2009)
Blood
, vol.113
, pp. 1875-1891
-
-
Sanz, M.A.1
Grimwade, D.2
Tallman, M.S.3
Lowenberg, B.4
Fenaux, P.5
Estey, E.H.6
-
79
-
-
36148948610
-
Detecting PML-RARalpha transcript in acute promyelocytic leukemia using real-time quantitative RT-PCR
-
Zhu HH, Liu YR, Qin YZ, Jiang B, Shan FX, Wu SL, et al. Detecting PML-RARalpha transcript in acute promyelocytic leukemia using real-time quantitative RT-PCR. Chin Med J 2007; 120: 1803-1808.
-
(2007)
Chin Med J
, vol.120
, pp. 1803-1808
-
-
Zhu, H.H.1
Liu, Y.R.2
Qin, Y.Z.3
Jiang, B.4
Shan, F.X.5
Wu, S.L.6
-
80
-
-
0030923479
-
All-trans-retinoic acid in acute promyelocytic leukemia
-
Tallman MS, Andersen JW, Schiffer CA, Appelbaum FR, Feusner JH, Ogden A, et al. All-trans-retinoic acid in acute promyelocytic leukemia. N Engl J Med 1997; 337: 1021-1028.
-
(1997)
N Engl J Med
, vol.337
, pp. 1021-1028
-
-
Tallman, M.S.1
Andersen, J.W.2
Schiffer, C.A.3
Appelbaum, F.R.4
Feusner, J.H.5
Ogden, A.6
-
81
-
-
3843063490
-
Extramedullary infiltrates of AML are associated with CD56 expression, 11q23 abnormalities and inferior clinical outcome
-
Chang H, Brandwein J, Yi QL, Chun K, Patterson B, Brien B. Extramedullary infiltrates of AML are associated with CD56 expression, 11q23 abnormalities and inferior clinical outcome. Leuk Res 2004; 28: 1007-1011.
-
(2004)
Leuk Res
, vol.28
, pp. 1007-1011
-
-
Chang, H.1
Brandwein, J.2
Yi, Q.L.3
Chun, K.4
Patterson, B.5
Brien, B.6
-
82
-
-
0029055430
-
Extramedullary myeloid cell tumors in acute nonlymphocytic leukemia: A clinical review
-
Byrd JC, Edenfield WJ, Shields DJ, Dawson NA. Extramedullary myeloid cell tumors in acute nonlymphocytic leukemia: a clinical review. J Clin Oncol 1995; 13: 1800-1816.
-
(1995)
J Clin Oncol
, vol.13
, pp. 1800-1816
-
-
Byrd, J.C.1
Edenfield, W.J.2
Shields, D.J.3
Dawson, N.A.4
-
83
-
-
33846499100
-
Extramedullary disease and targeted therapies for hematological malignancies-is the association real?
-
Raanani P, Shpilberg O, Ben-Bassat I. Extramedullary disease and targeted therapies for hematological malignancies-is the association real? Ann Oncol 2007; 18: 7-12.
-
(2007)
Ann Oncol
, vol.18
, pp. 7-12
-
-
Raanani, P.1
Shpilberg, O.2
Ben-Bassat, I.3
-
84
-
-
33847379392
-
Extramedullary infiltration at diagnosis and prognosis in children with acute myelogenous leukemia
-
Kobayashi R, Tawa A, Hanada R, Horibe K, Tsuchida M, Tsukimoto I. Extramedullary infiltration at diagnosis and prognosis in children with acute myelogenous leukemia. Pediatr Blood Cancer 2007; 48: 393-398.
-
(2007)
Pediatr Blood Cancer
, vol.48
, pp. 393-398
-
-
Kobayashi, R.1
Tawa, A.2
Hanada, R.3
Horibe, K.4
Tsuchida, M.5
Tsukimoto, I.6
-
85
-
-
40749099021
-
Current management and challenges of malignant disease in the CNS in paediatric leukaemia
-
Pui CH, Howard SC. Current management and challenges of malignant disease in the CNS in paediatric leukaemia. Lancet Oncol 2008; 9: 257-268.
-
(2008)
Lancet Oncol
, vol.9
, pp. 257-268
-
-
Pui, C.H.1
Howard, S.C.2
-
86
-
-
0031451599
-
The value of combination therapy in adult acute myeloid leukemia with central nervous system involvement
-
Castagnola C, Nozza A, Corso A, Bernasconi C. The value of combination therapy in adult acute myeloid leukemia with central nervous system involvement. Haematologica 1997; 82: 577-580.
-
(1997)
Haematologica
, vol.82
, pp. 577-580
-
-
Castagnola, C.1
Nozza, A.2
Corso, A.3
Bernasconi, C.4
-
87
-
-
5444268197
-
Phase I trial of intrathecal liposomal cytarabine in children with neoplastic meningitis
-
Bomgaars L, Geyer JR, Franklin J, Dahl G, Park J, Winick NJ, et al. Phase I trial of intrathecal liposomal cytarabine in children with neoplastic meningitis. J Clin Oncol 2004; 22: 3916-3921.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3916-3921
-
-
Bomgaars, L.1
Geyer, J.R.2
Franklin, J.3
Dahl, G.4
Park, J.5
Winick, N.J.6
-
88
-
-
33747199596
-
Intrathecal triple therapy decreases central nervous system relapse but fails to improve event-free survival when compared with intrathecal methotrexate: Results of the Children's Cancer Group (CCG) 1952 study for standard-risk acute lymphoblastic leukemia, reported by the Children's Oncology Group
-
Matloub Y, Lindemulder S, Gaynon PS, Sather H, La M, Broxson E, et al. Intrathecal triple therapy decreases central nervous system relapse but fails to improve event-free survival when compared with intrathecal methotrexate: results of the Children's Cancer Group (CCG) 1952 study for standard-risk acute lymphoblastic leukemia, reported by the Children's Oncology Group. Blood 2006; 108: 1165-1173.
-
(2006)
Blood
, vol.108
, pp. 1165-1173
-
-
Matloub, Y.1
Lindemulder, S.2
Gaynon, P.S.3
Sather, H.4
La, M.5
Broxson, E.6
-
90
-
-
6044229354
-
Concepts of human leukemic development
-
Warner JK, Wang JC, Hope KJ, Jin L, Dick JE. Concepts of human leukemic development. Oncogene 2004; 23: 7164-7177.
-
(2004)
Oncogene
, vol.23
, pp. 7164-7177
-
-
Warner, J.K.1
Wang, J.C.2
Hope, K.J.3
Jin, L.4
Dick, J.E.5
-
91
-
-
34548688894
-
Establishing long-term cultures with self-renewing acute myeloid leukemia stem/progenitor cells
-
van Gosliga D, Schepers H, Rizo A, van der Kolk D, Vellenga E, Schuringa JJ. Establishing long-term cultures with self-renewing acute myeloid leukemia stem/progenitor cells. Exp Hematol 2007; 35: 1538-1549.
-
(2007)
Exp Hematol
, vol.35
, pp. 1538-1549
-
-
van Gosliga, D.1
Schepers, H.2
Rizo, A.3
van der Kolk, D.4
Vellenga, E.5
Schuringa, J.J.6
-
92
-
-
0033815950
-
The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells
-
Jordan CT, Upchurch D, Szilvassy SJ, Guzman ML, Howard DS, Pettigrew AL, et al. The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells. Leukemia 2000; 14: 1777-1784.
-
(2000)
Leukemia
, vol.14
, pp. 1777-1784
-
-
Jordan, C.T.1
Upchurch, D.2
Szilvassy, S.J.3
Guzman, M.L.4
Howard, D.S.5
Pettigrew, A.L.6
-
93
-
-
34547415968
-
CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia
-
Hosen N, Park CY, Tatsumi N, Oji Y, Sugiyama H, Gramatzki M, et al. CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia. Proc Natl Acad Sci U S A 2007; 104: 11008-11013.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11008-11013
-
-
Hosen, N.1
Park, C.Y.2
Tatsumi, N.3
Oji, Y.4
Sugiyama, H.5
Gramatzki, M.6
-
94
-
-
34948839959
-
The novel AML stem cell associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells
-
van Rhenen A, van Dongen GA, Kelder A, Rombouts EJ, Feller N, Moshaver B, et al. The novel AML stem cell associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells. Blood 2007; 110: 2659-2666.
-
(2007)
Blood
, vol.110
, pp. 2659-2666
-
-
van Rhenen, A.1
van Dongen, G.A.2
Kelder, A.3
Rombouts, E.J.4
Feller, N.5
Moshaver, B.6
-
95
-
-
67649200331
-
Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells
-
Jin L, Lee EM, Ramshaw HS, Busfield SJ, Peoppl AG, Wilkinson L, et al. Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells. Cell Stem Cell 2009; 5: 31-42.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 31-42
-
-
Jin, L.1
Lee, E.M.2
Ramshaw, H.S.3
Busfield, S.J.4
Peoppl, A.G.5
Wilkinson, L.6
-
96
-
-
0034900174
-
Approval summary: Gemtuzumab ozogamicin in relapsed acute myeloid leukemia
-
Bross PF, Beitz J, Chen G, Chen XH, Duffy E, Kieffer L, et al. Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia. Clin Cancer Res 2001; 7: 1490-1496.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1490-1496
-
-
Bross, P.F.1
Beitz, J.2
Chen, G.3
Chen, X.H.4
Duffy, E.5
Kieffer, L.6
-
97
-
-
0036733277
-
Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin)
-
Larson RA, Boogaerts M, Estey E, Karanes C, Stadtmauer EA, Sievers EL, et al. Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin). Leukemia 2002; 16: 1627-1636.
-
(2002)
Leukemia
, vol.16
, pp. 1627-1636
-
-
Larson, R.A.1
Boogaerts, M.2
Estey, E.3
Karanes, C.4
Stadtmauer, E.A.5
Sievers, E.L.6
-
98
-
-
0035397980
-
Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse
-
Sievers EL, Larson RA, Stadtmauer EA, Estey E, Lowenberg B, Dombret H, et al. Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse. J Clin Oncol 2001; 19: 3244-3254.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3244-3254
-
-
Sievers, E.L.1
Larson, R.A.2
Stadtmauer, E.A.3
Estey, E.4
Lowenberg, B.5
Dombret, H.6
-
99
-
-
28844456971
-
Hematopoietic stem cells express multiple myeloid markers: Implications for the origin and targeted therapy of acute myeloid leukemia
-
Taussig DC, Pearce DJ, Simpson C, Rohatiner AZ, Lister TA, Kelly G, et al. Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia. Blood 2005; 106: 4086-4092.
-
(2005)
Blood
, vol.106
, pp. 4086-4092
-
-
Taussig, D.C.1
Pearce, D.J.2
Simpson, C.3
Rohatiner, A.Z.4
Lister, T.A.5
Kelly, G.6
-
100
-
-
4644293319
-
Gemtuzumab ozogamicin (Mylotarg) as a single agent for molecularly relapsed acute promyelocytic leukemia
-
Lo-Coco F, Cimino G, Breccia M, Noguera NI, Diverio D, Finolezzi E, et al. Gemtuzumab ozogamicin (Mylotarg) as a single agent for molecularly relapsed acute promyelocytic leukemia. Blood 2004; 104: 1995-1999.
-
(2004)
Blood
, vol.104
, pp. 1995-1999
-
-
Lo-Coco, F.1
Cimino, G.2
Breccia, M.3
Noguera, N.I.4
Diverio, D.5
Finolezzi, E.6
-
101
-
-
67650646082
-
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis
-
Jaiswal S, Jamieson CH, Pang WW, Park CY, Chao MP, Majeti R, et al. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell 2009; 138: 271-285.
-
(2009)
Cell
, vol.138
, pp. 271-285
-
-
Jaiswal, S.1
Jamieson, C.H.2
Pang, W.W.3
Park, C.Y.4
Chao, M.P.5
Majeti, R.6
-
102
-
-
67650632683
-
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells
-
Majeti R, Chao MP, Alizadeh AA, Pang WW, Jaiswal S, Gibbs KD Jr, et al. CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell 2009; 138: 286-299.
-
(2009)
Cell
, vol.138
, pp. 286-299
-
-
Majeti, R.1
Chao, M.P.2
Alizadeh, A.A.3
Pang, W.W.4
Jaiswal, S.5
Gibbs Jr., K.D.6
-
103
-
-
33845240584
-
Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: Safety, pharmacokinetics, and pharmacodynamics
-
DeAngelo DJ, Stone RM, Heaney ML, Nimer SD, Paquette RL, Klisovic RB, et al. Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: safety, pharmacokinetics, and pharmacodynamics. Blood 2006; 108: 3674-3681.
-
(2006)
Blood
, vol.108
, pp. 3674-3681
-
-
DeAngelo, D.J.1
Stone, R.M.2
Heaney, M.L.3
Nimer, S.D.4
Paquette, R.L.5
Klisovic, R.B.6
-
104
-
-
0141993064
-
A phase 2 clinical study of SU5416 in patients with refractory acute myeloid leukemia
-
Fiedler W, Mesters R, Tinnefeld H, Loges S, Staib P, Duhrsen U, et al. A phase 2 clinical study of SU5416 in patients with refractory acute myeloid leukemia. Blood 2003; 102: 2763-2767.
-
(2003)
Blood
, vol.102
, pp. 2763-2767
-
-
Fiedler, W.1
Mesters, R.2
Tinnefeld, H.3
Loges, S.4
Staib, P.5
Duhrsen, U.6
-
105
-
-
19944431093
-
A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease
-
Fiedler W, Serve H, Dohner H, Schwittay M, Ottmann OG, O'Farrell AM, et al. A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease. Blood 2005; 105: 986-993.
-
(2005)
Blood
, vol.105
, pp. 986-993
-
-
Fiedler, W.1
Serve, H.2
Dohner, H.3
Schwittay, M.4
Ottmann, O.G.5
O'Farrell, A.M.6
-
106
-
-
33751173636
-
A phase 2 trial of the FLT3 inhibitor lestaurtinib (CEP701) as first-line treatment for older patients with acute myeloid leukemia not considered fit for intensive chemotherapy
-
Knapper S, Burnett AK, Littlewood T, Kell WJ, Agrawal S, Chopra R, et al. A phase 2 trial of the FLT3 inhibitor lestaurtinib (CEP701) as first-line treatment for older patients with acute myeloid leukemia not considered fit for intensive chemotherapy. Blood 2006; 108: 3262-3270.
-
(2006)
Blood
, vol.108
, pp. 3262-3270
-
-
Knapper, S.1
Burnett, A.K.2
Littlewood, T.3
Kell, W.J.4
Agrawal, S.5
Chopra, R.6
-
107
-
-
62949087552
-
A pharmacodynamic study of the FLT3 inhibitor KW-2449 yields insight into the basis for clinical response
-
Pratz KW, Cortes J, Roboz GJ, Rao N, Arowojolu O, Stine A, et al. A pharmacodynamic study of the FLT3 inhibitor KW-2449 yields insight into the basis for clinical response. Blood 2009; 113: 3938-3946.
-
(2009)
Blood
, vol.113
, pp. 3938-3946
-
-
Pratz, K.W.1
Cortes, J.2
Roboz, G.J.3
Rao, N.4
Arowojolu, O.5
Stine, A.6
-
108
-
-
56949083913
-
Sorafenib (Nexavar) induces molecular remission and regression of extramedullary disease in a patient with FLT3-ITD+ acute myeloid leukemia
-
Safaian NN, Czibere A, Bruns I, Fenk R, Reinecke P, Dienst A, et al. Sorafenib (Nexavar) induces molecular remission and regression of extramedullary disease in a patient with FLT3-ITD+ acute myeloid leukemia. Leuk Res 2009; 33: 348-350.
-
(2009)
Leuk Res
, vol.33
, pp. 348-350
-
-
Safaian, N.N.1
Czibere, A.2
Bruns, I.3
Fenk, R.4
Reinecke, P.5
Dienst, A.6
-
109
-
-
19944427559
-
Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
-
Stone RM, DeAngelo DJ, Klimek V, Galinsky I, Estey E, Nimer SD, et al. Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412. Blood 2005; 105: 54-60.
-
(2005)
Blood
, vol.105
, pp. 54-60
-
-
Stone, R.M.1
DeAngelo, D.J.2
Klimek, V.3
Galinsky, I.4
Estey, E.5
Nimer, S.D.6
-
110
-
-
72249087752
-
Identification of N-(5-tert-Butyl-isoxazol-3-yl)-N'-(4-(7-(2-morpholin-4-yl-ethoxy) imidazo (2,1-b)(1,3) benzothiazol-2-yl) phenyl)urea Dihydrochloride (AC220), a uniquely potent, selective, and efficacious FMS-Like tyrosine kinase-3 (FLT3) inhibitor
-
Chao Q, Sprankle KG, Grotzfeld RM, Lai AG, Carter TA, Velasco AM, et al. Identification of N-(5-tert-Butyl-isoxazol-3-yl)-N'-(4-(7-(2-morpholin-4-yl-ethoxy) imidazo (2,1-b)(1,3) benzothiazol-2-yl) phenyl)urea Dihydrochloride (AC220), a uniquely potent, selective, and efficacious FMS-Like tyrosine kinase-3 (FLT3) inhibitor. J Med Chem 2009; 52: 7808-7816
-
(2009)
J Med Chem
, vol.52
, pp. 7808-7816
-
-
Chao, Q.1
Sprankle, K.G.2
Grotzfeld, R.M.3
Lai, A.G.4
Carter, T.A.5
Velasco, A.M.6
-
111
-
-
70449475105
-
AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)
-
Zarrinkar PP, Gunawardane RN, Cramer MD, Gardner MF, Brigham D, Belli B, et al. AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). Blood 2009; 114: 2984-2992.
-
(2009)
Blood
, vol.114
, pp. 2984-2992
-
-
Zarrinkar, P.P.1
Gunawardane, R.N.2
Cramer, M.D.3
Gardner, M.F.4
Brigham, D.5
Belli, B.6
-
112
-
-
67650367598
-
Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML
-
Zeng Z, Shi YX, Samudio IJ, Wang RY, Ling X, Frolova O, et al. Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML. Blood 2009; 113: 6215-6224.
-
(2009)
Blood
, vol.113
, pp. 6215-6224
-
-
Zeng, Z.1
Shi, Y.X.2
Samudio, I.J.3
Wang, R.Y.4
Ling, X.5
Frolova, O.6
-
113
-
-
44049086446
-
Cooperating gene mutations in acute myeloid leukemia: A review of the literature
-
Renneville A, Roumier C, Biggio V, Nibourel O, Boissel N, Fenaux P, et al. Cooperating gene mutations in acute myeloid leukemia: a review of the literature. Leukemia 2008; 22: 915-931.
-
(2008)
Leukemia
, vol.22
, pp. 915-931
-
-
Renneville, A.1
Roumier, C.2
Biggio, V.3
Nibourel, O.4
Boissel, N.5
Fenaux, P.6
-
114
-
-
0034254249
-
Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor
-
Heinrich MC, Griffith DJ, Druker BJ, Wait CL, Ott KA, Zigler AJ. Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood 2000; 96: 925-932.
-
(2000)
Blood
, vol.96
, pp. 925-932
-
-
Heinrich, M.C.1
Griffith, D.J.2
Druker, B.J.3
Wait, C.L.4
Ott, K.A.5
Zigler, A.J.6
-
115
-
-
0038731316
-
Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant
-
Frost MJ, Ferrao PT, Hughes TP, Ashman LK. Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant. Mol Cancer Ther 2002; 1: 1115-1124.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 1115-1124
-
-
Frost, M.J.1
Ferrao, P.T.2
Hughes, T.P.3
Ashman, L.K.4
-
116
-
-
0036493872
-
The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations
-
Ma Y, Zeng S, Metcalfe DD, Akin C, Dimitrijevic S, Butterfield JH, et al. The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations. Blood 2002; 99: 1741-1744.
-
(2002)
Blood
, vol.99
, pp. 1741-1744
-
-
Ma, Y.1
Zeng, S.2
Metcalfe, D.D.3
Akin, C.4
Dimitrijevic, S.5
Butterfield, J.H.6
-
117
-
-
19944428353
-
Discovery of N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)-piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays
-
Lombardo LJ, Lee FY, Chen P, Norris D, Barrish JC, Behnia K, et al. Discovery of N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)-piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. J Med Chem 2004; 47: 6658-6661.
-
(2004)
J Med Chem
, vol.47
, pp. 6658-6661
-
-
Lombardo, L.J.1
Lee, F.Y.2
Chen, P.3
Norris, D.4
Barrish, J.C.5
Behnia, K.6
-
118
-
-
31544459272
-
Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies
-
Schittenhelm MM, Shiraga S, Schroeder A, Corbin AS, Griffith D, Lee FY, et al. Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies. Cancer Res 2006; 66: 473-481.
-
(2006)
Cancer Res
, vol.66
, pp. 473-481
-
-
Schittenhelm, M.M.1
Shiraga, S.2
Schroeder, A.3
Corbin, A.S.4
Griffith, D.5
Lee, F.Y.6
-
119
-
-
42349094624
-
Initial testing of dasatinib by the pediatric preclinical testing program
-
Kolb EA, Gorlick R, Houghton PJ, Morton CL, Lock RB, Tajbakhsh M, et al. Initial testing of dasatinib by the pediatric preclinical testing program. Pediatr Blood Cancer 2008; 50: 1198-1206.
-
(2008)
Pediatr Blood Cancer
, vol.50
, pp. 1198-1206
-
-
Kolb, E.A.1
Gorlick, R.2
Houghton, P.J.3
Morton, C.L.4
Lock, R.B.5
Tajbakhsh, M.6
-
120
-
-
61449256026
-
Chemotherapy and dasatinib induce long-term hematologic and molecular remission in systemic mastocytosis with acute myeloid leukemia with KIT D816V
-
Ustun C, Corless CL, Savage N, Fiskus W, Manaloor E, Heinrich MC, et al. Chemotherapy and dasatinib induce long-term hematologic and molecular remission in systemic mastocytosis with acute myeloid leukemia with KIT D816V. Leuk Res 2009; 33: 735-741.
-
(2009)
Leuk Res
, vol.33
, pp. 735-741
-
-
Ustun, C.1
Corless, C.L.2
Savage, N.3
Fiskus, W.4
Manaloor, E.5
Heinrich, M.C.6
-
121
-
-
65949085380
-
Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells
-
Faderl S, Pal A, Bornmann W, Albitar M, Maxwell D, Van Q, et al. Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. Cancer Res 2009; 69: 3910-3917.
-
(2009)
Cancer Res
, vol.69
, pp. 3910-3917
-
-
Faderl, S.1
Pal, A.2
Bornmann, W.3
Albitar, M.4
Maxwell, D.5
Van, Q.6
-
122
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J. Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 2003; 3: 11-22.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
123
-
-
33847001315
-
A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia
-
Lancet JE, Gojo I, Gotlib J, Feldman EJ, Greer J, Liesveld JL, et al. A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia. Blood 2007; 109: 1387-1394.
-
(2007)
Blood
, vol.109
, pp. 1387-1394
-
-
Lancet, J.E.1
Gojo, I.2
Gotlib, J.3
Feldman, E.J.4
Greer, J.5
Liesveld, J.L.6
-
124
-
-
34250006852
-
A phase 2 study of the oral farnesyltransferase inhibitor tipifarnib in patients with refractory or relapsed acute myeloid leukemia
-
Harousseau JL, Lancet JE, Reiffers J, Lowenberg B, Thomas X, Huguet F, et al. A phase 2 study of the oral farnesyltransferase inhibitor tipifarnib in patients with refractory or relapsed acute myeloid leukemia. Blood 2007; 109: 5151-5156.
-
(2007)
Blood
, vol.109
, pp. 5151-5156
-
-
Harousseau, J.L.1
Lancet, J.E.2
Reiffers, J.3
Lowenberg, B.4
Thomas, X.5
Huguet, F.6
-
125
-
-
49649116897
-
Phase II trial of tipifarnib as maintenance therapy in first complete remission in adults with acute myelogenous leukemia and poor-risk features
-
Karp JE, Smith BD, Gojo I, Lancet JE, Greer J, Klein M, et al. Phase II trial of tipifarnib as maintenance therapy in first complete remission in adults with acute myelogenous leukemia and poor-risk features. Clin Cancer Res 2008; 14: 3077-3082.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3077-3082
-
-
Karp, J.E.1
Smith, B.D.2
Gojo, I.3
Lancet, J.E.4
Greer, J.5
Klein, M.6
-
126
-
-
41949125894
-
A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia
-
Raponi M, Lancet JE, Fan H, Dossey L, Lee G, Gojo I, et al. A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia. Blood 2008; 111: 2589-2596.
-
(2008)
Blood
, vol.111
, pp. 2589-2596
-
-
Raponi, M.1
Lancet, J.E.2
Fan, H.3
Dossey, L.4
Lee, G.5
Gojo, I.6
-
127
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128: 683-692.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
128
-
-
58149235277
-
Histone deacetylase inhibitor romidepsin has differential activity in core binding factor acute myeloid leukemia
-
Odenike OM, Alkan S, Sher D, Godwin JE, Huo D, Brandt SJ, et al. Histone deacetylase inhibitor romidepsin has differential activity in core binding factor acute myeloid leukemia. Clin Cancer Res 2008; 14: 7095-7101.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7095-7101
-
-
Odenike, O.M.1
Alkan, S.2
Sher, D.3
Godwin, J.E.4
Huo, D.5
Brandt, S.J.6
-
129
-
-
29744454120
-
The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia
-
Kuendgen A, Schmid M, Schlenk R, Knipp S, Hildebrandt B, Steidl C, et al. The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia. Cancer 2006; 106: 112-119.
-
(2006)
Cancer
, vol.106
, pp. 112-119
-
-
Kuendgen, A.1
Schmid, M.2
Schlenk, R.3
Knipp, S.4
Hildebrandt, B.5
Steidl, C.6
-
130
-
-
29144501152
-
Butyrates and decitabine cooperate to induce histone acetylation and granulocytic maturation of t(8;21) acute myeloid leukemia blasts
-
Gozzini A, Santini V. Butyrates and decitabine cooperate to induce histone acetylation and granulocytic maturation of t(8;21) acute myeloid leukemia blasts. Ann Hematol 2005; 84 Suppl 1: 54-60.
-
(2005)
Ann Hematol
, vol.84
, Issue.SUPPL. 1
, pp. 54-60
-
-
Gozzini, A.1
Santini, V.2
-
131
-
-
51649110503
-
Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia
-
Garcia-Manero G, Assouline S, Cortes J, Estrov Z, Kantarjian H, Yang H, et al. Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia. Blood 2008; 112: 981-989.
-
(2008)
Blood
, vol.112
, pp. 981-989
-
-
Garcia-Manero, G.1
Assouline, S.2
Cortes, J.3
Estrov, Z.4
Kantarjian, H.5
Yang, H.6
-
132
-
-
53449090857
-
Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells
-
Fiskus W, Rao R, Fernandez P, Herger B, Yang Y, Chen J, et al. Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells. Blood 2008; 112: 2896-2905.
-
(2008)
Blood
, vol.112
, pp. 2896-2905
-
-
Fiskus, W.1
Rao, R.2
Fernandez, P.3
Herger, B.4
Yang, Y.5
Chen, J.6
-
133
-
-
73149099172
-
Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities
-
Ravandi F, Issa JP, Garcia-Manero G, O'Brien S, Pierce S, Shan J, et al. Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities. Cancer 2009; 115: 5746-5751.
-
(2009)
Cancer
, vol.115
, pp. 5746-5751
-
-
Ravandi, F.1
Issa, J.P.2
Garcia-Manero, G.3
O'Brien, S.4
Pierce, S.5
Shan, J.6
-
134
-
-
62849104641
-
Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: A randomised, open-label, phase III study
-
Fenaux P, Mufti GJ, Hellstrom-Lindberg E, Santini V, Finelli C, Giagounidis A, et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 2009; 10: 223-232.
-
(2009)
Lancet Oncol
, vol.10
, pp. 223-232
-
-
Fenaux, P.1
Mufti, G.J.2
Hellstrom-Lindberg, E.3
Santini, V.4
Finelli, C.5
Giagounidis, A.6
-
135
-
-
77449149373
-
Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia
-
Fenaux P, Mufti GJ, Hellstrom-Lindberg E, Santini V, Gattermann N, Germing U, et al. Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia. J Clin Oncol 2010; 28: 562-569.
-
(2010)
J Clin Oncol
, vol.28
, pp. 562-569
-
-
Fenaux, P.1
Mufti, G.J.2
Hellstrom-Lindberg, E.3
Santini, V.4
Gattermann, N.5
Germing, U.6
-
136
-
-
70350506791
-
Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies
-
Fandy TE, Herman JG, Kerns P, Jiemjit A, Sugar EA, Choi SH, et al. Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies. Blood 2009; 114: 2764-2773.
-
(2009)
Blood
, vol.114
, pp. 2764-2773
-
-
Fandy, T.E.1
Herman, J.G.2
Kerns, P.3
Jiemjit, A.4
Sugar, E.A.5
Choi, S.H.6
-
137
-
-
0035886024
-
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
-
Guzman ML, Neering SJ, Upchurch D, Grimes B, Howard DS, Rizzieri DA, et al. Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 2001; 98: 2301-2307.
-
(2001)
Blood
, vol.98
, pp. 2301-2307
-
-
Guzman, M.L.1
Neering, S.J.2
Upchurch, D.3
Grimes, B.4
Howard, D.S.5
Rizzieri, D.A.6
-
138
-
-
0742272099
-
Constitutive NF-kappaB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway
-
Birkenkamp KU, Geugien M, Schepers H, Westra J, Lemmink HH, Vellenga E. Constitutive NF-kappaB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway. Leukemia 2004; 18: 103-112.
-
(2004)
Leukemia
, vol.18
, pp. 103-112
-
-
Birkenkamp, K.U.1
Geugien, M.2
Schepers, H.3
Westra, J.4
Lemmink, H.H.5
Vellenga, E.6
-
139
-
-
0037059012
-
Preferential induction of apoptosis for primary human leukemic stem cells
-
Guzman ML, Swiderski CF, Howard DS, Grimes BA, Rossi RM, Szilvassy SJ, et al. Preferential induction of apoptosis for primary human leukemic stem cells. Proc Natl Acad Sci U S A 2002; 99: 16220-16225.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 16220-16225
-
-
Guzman, M.L.1
Swiderski, C.F.2
Howard, D.S.3
Grimes, B.A.4
Rossi, R.M.5
Szilvassy, S.J.6
-
140
-
-
0034660068
-
Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins
-
Konopleva M, Tari AM, Estrov Z, Harris D, Xie Z, Zhao S, et al. Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins. Blood 2000; 95: 3929-3938.
-
(2000)
Blood
, vol.95
, pp. 3929-3938
-
-
Konopleva, M.1
Tari, A.M.2
Estrov, Z.3
Harris, D.4
Xie, Z.5
Zhao, S.6
-
141
-
-
0037438586
-
Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia
-
Marcucci G, Byrd JC, Dai G, Klisovic MI, Kourlas PJ, Young DC, et al. Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia. Blood 2003; 101: 425-432.
-
(2003)
Blood
, vol.101
, pp. 425-432
-
-
Marcucci, G.1
Byrd, J.C.2
Dai, G.3
Klisovic, M.I.4
Kourlas, P.J.5
Young, D.C.6
-
142
-
-
20644469046
-
Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia: Pharmacokinetics, pharmacodynamics, and clinical activity
-
Marcucci G, Stock W, Dai G, Klisovic RB, Liu S, Klisovic MI, et al. Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia: pharmacokinetics, pharmacodynamics, and clinical activity. J Clin Oncol 2005; 23: 3404-3411.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3404-3411
-
-
Marcucci, G.1
Stock, W.2
Dai, G.3
Klisovic, R.B.4
Liu, S.5
Klisovic, M.I.6
-
143
-
-
33749017910
-
Signaling pathways in self-renewing hematopoietic and leukemic stem cells: Do all stem cells need a niche?
-
Rizo A, Vellenga E, de Haan G, Schuringa JJ. Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche? Hum Mol Genet 2006; 15: R210-R219.
-
(2006)
Hum Mol Genet
, vol.15
-
-
Rizo, A.1
Vellenga, E.2
de Haan, G.3
Schuringa, J.J.4
-
144
-
-
41149109622
-
Uncertainty in the niches that maintain haematopoietic stem cells
-
Kiel MJ, Morrison SJ. Uncertainty in the niches that maintain haematopoietic stem cells. Nat Rev Immunol 2008; 8: 290-301.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 290-301
-
-
Kiel, M.J.1
Morrison, S.J.2
-
145
-
-
69849104865
-
The leukemic stem cell niche: Current concepts and therapeutic opportunities
-
Lane SW, Scadden DT, Gilliland DG. The leukemic stem cell niche: current concepts and therapeutic opportunities. Blood 2009; 114: 1150-1157.
-
(2009)
Blood
, vol.114
, pp. 1150-1157
-
-
Lane, S.W.1
Scadden, D.T.2
Gilliland, D.G.3
-
146
-
-
34247171303
-
Expansion of normal and leukemic human hematopoietic stem/progenitor cells requires rac-mediated interaction with stromal cells
-
Rozenveld-Geugien M, Baas IO, van Gosliga D, Vellenga E, Schuringa JJ. Expansion of normal and leukemic human hematopoietic stem/progenitor cells requires rac-mediated interaction with stromal cells. Exp Hematol 2007; 35: 782-792.
-
(2007)
Exp Hematol
, vol.35
, pp. 782-792
-
-
Rozenveld-Geugien, M.1
Baas, I.O.2
van Gosliga, D.3
Vellenga, E.4
Schuringa, J.J.5
-
147
-
-
33749515476
-
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
-
Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med 2006; 12: 1167-1174.
-
(2006)
Nat Med
, vol.12
, pp. 1167-1174
-
-
Jin, L.1
Hope, K.J.2
Zhai, Q.3
Smadja-Joffe, F.4
Dick, J.E.5
-
148
-
-
33749521890
-
Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells
-
Krause DS, Lazarides K, von Andrian UH, Van Etten RA. Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells. Nat Med 2006; 12: 1175-1180.
-
(2006)
Nat Med
, vol.12
, pp. 1175-1180
-
-
Krause, D.S.1
Lazarides, K.2
von Andrian, U.H.3
van Etten, R.A.4
-
149
-
-
33846241600
-
CXCR4 is a prognostic marker in acute myelogenous leukemia
-
Spoo AC, Lubbert M, Wierda WG, Burger JA. CXCR4 is a prognostic marker in acute myelogenous leukemia. Blood 2007; 109: 786-791.
-
(2007)
Blood
, vol.109
, pp. 786-791
-
-
Spoo, A.C.1
Lubbert, M.2
Wierda, W.G.3
Burger, J.A.4
-
150
-
-
35448936860
-
Effects of AMD3100 on transmigration and survival of acute myelogenous leukemia cells
-
Liesveld JL, Bechelli J, Rosell K, Lu C, Bridger G, Phillips G, et al. Effects of AMD3100 on transmigration and survival of acute myelogenous leukemia cells. Leuk Res 2007; 31: 1553-1563.
-
(2007)
Leuk Res
, vol.31
, pp. 1553-1563
-
-
Liesveld, J.L.1
Bechelli, J.2
Rosell, K.3
Lu, C.4
Bridger, G.5
Phillips, G.6
-
151
-
-
67650410440
-
Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100
-
Nervi B, Ramirez P, Rettig MP, Uy GL, Holt MS, Ritchey JK, et al. Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100. Blood 2009; 113: 6206-6214.
-
(2009)
Blood
, vol.113
, pp. 6206-6214
-
-
Nervi, B.1
Ramirez, P.2
Rettig, M.P.3
Uy, G.L.4
Holt, M.S.5
Ritchey, J.K.6
-
152
-
-
0342460479
-
Value of different modalities of granulocyte-macrophage colony-stimulating factor applied during or after induction therapy of acute myeloid leukemia
-
Lowenberg B, Boogaerts MA, Daenen SM, Verhoef GE, Hagenbeek A, Vellenga E, et al. Value of different modalities of granulocyte-macrophage colony-stimulating factor applied during or after induction therapy of acute myeloid leukemia. J Clin Oncol 1997; 15: 3496-3506.
-
(1997)
J Clin Oncol
, vol.15
, pp. 3496-3506
-
-
Lowenberg, B.1
Boogaerts, M.A.2
Daenen, S.M.3
Verhoef, G.E.4
Hagenbeek, A.5
Vellenga, E.6
-
153
-
-
9144238671
-
A phase 3 study of three induction regimens and of priming with GM-CSF in older adults with acute myeloid leukemia: A trial by the Eastern Cooperative Oncology Group
-
Rowe JM, Neuberg D, Friedenberg W, Bennett JM, Paietta E, Makary AZ, et al. A phase 3 study of three induction regimens and of priming with GM-CSF in older adults with acute myeloid leukemia: a trial by the Eastern Cooperative Oncology Group. Blood 2004; 103: 479-485.
-
(2004)
Blood
, vol.103
, pp. 479-485
-
-
Rowe, J.M.1
Neuberg, D.2
Friedenberg, W.3
Bennett, J.M.4
Paietta, E.5
Makary, A.Z.6
-
154
-
-
33847202969
-
Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: A trial by the Acute Leukemia French Association (ALFA) Group
-
Thomas X, Raffoux E, Botton S, Pautas C, Arnaud P, de Revel T, et al. Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group. Leukemia 2007; 21: 453-461.
-
(2007)
Leukemia
, vol.21
, pp. 453-461
-
-
Thomas, X.1
Raffoux, E.2
Botton, S.3
Pautas, C.4
Arnaud, P.5
de Revel, T.6
-
155
-
-
66549108083
-
CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions
-
Eash KJ, Means JM, White DW, Link DC. CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions. Blood 2009; 113: 4711-4719.
-
(2009)
Blood
, vol.113
, pp. 4711-4719
-
-
Eash, K.J.1
Means, J.M.2
White, D.W.3
Link, D.C.4
-
157
-
-
0031764330
-
Clinical relevance of transmembrane drug efflux as a mechanism of multidrug resistance
-
Bradshaw DM, Arceci RJ. Clinical relevance of transmembrane drug efflux as a mechanism of multidrug resistance. J Clin Oncol 1998; 16: 3674-3690.
-
(1998)
J Clin Oncol
, vol.16
, pp. 3674-3690
-
-
Bradshaw, D.M.1
Arceci, R.J.2
-
158
-
-
1842457644
-
Mitoxantrone, etoposide, and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome: A phase III trial (E2995)
-
Greenberg PL, Lee SJ, Advani R, Tallman MS, Sikic BI, Letendre L, et al. Mitoxantrone, etoposide, and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome: a phase III trial (E2995). J Clin Oncol 2004; 22: 1078-1086.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1078-1086
-
-
Greenberg, P.L.1
Lee, S.J.2
Advani, R.3
Tallman, M.S.4
Sikic, B.I.5
Letendre, L.6
-
159
-
-
27144508406
-
The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis
-
van der Holt B, Lowenberg B, Burnett AK, Knauf WU, Shepherd J, Piccaluga PP, et al. The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis. Blood 2005; 106: 2646-2654.
-
(2005)
Blood
, vol.106
, pp. 2646-2654
-
-
van der Holt, B.1
Lowenberg, B.2
Burnett, A.K.3
Knauf, W.U.4
Shepherd, J.5
Piccaluga, P.P.6
-
160
-
-
0037079708
-
The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors
-
Scharenberg CW, Harkey MA, Torok-Storb B. The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors. Blood 2002; 99: 507-512.
-
(2002)
Blood
, vol.99
, pp. 507-512
-
-
Scharenberg, C.W.1
Harkey, M.A.2
Torok-Storb, B.3
-
161
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakacs G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM. Targeting multidrug resistance in cancer. Nat Rev Drug Discov 2006; 5: 219-234.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 219-234
-
-
Szakacs, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
162
-
-
0035009960
-
Increased bone marrow vascularization in patients with acute myeloid leukaemia: A possible role for vascular endothelial growth factor
-
de Bont ES, Rosati S, Jacobs S, Kamps WA, Vellenga E. Increased bone marrow vascularization in patients with acute myeloid leukaemia: a possible role for vascular endothelial growth factor. Br J Haematol 2001; 113: 296-304.
-
(2001)
Br J Haematol
, vol.113
, pp. 296-304
-
-
de Bont, E.S.1
Rosati, S.2
Jacobs, S.3
Kamps, W.A.4
Vellenga, E.5
-
163
-
-
0037114642
-
In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo
-
Schuch G, Machluf M, Bartsch G Jr, Nomi M, Richard H, Atala A, et al. In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo. Blood 2002; 100: 4622-4628.
-
(2002)
Blood
, vol.100
, pp. 4622-4628
-
-
Schuch, G.1
Machluf, M.2
Bartsch Jr., G.3
Nomi, M.4
Richard, H.5
Atala, A.6
-
164
-
-
2542547507
-
Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous leukemias: Therapy with sequential 1-beta-d-arabinofuranosylcytosine, mitoxantrone, and bevacizumab
-
Karp JE, Gojo I, Pili R, Gocke CD, Greer J, Guo C, et al. Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous leukemias: therapy with sequential 1-beta-d-arabinofuranosylcytosine, mitoxantrone, and bevacizumab. Clin Cancer Res 2004; 10: 3577-3585.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3577-3585
-
-
Karp, J.E.1
Gojo, I.2
Pili, R.3
Gocke, C.D.4
Greer, J.5
Guo, C.6
-
165
-
-
0036464605
-
Efficacy and safety of thalidomide in patients with acute myeloid leukemia
-
Steins MB, Padro T, Bieker R, Ruiz S, Kropff M, Kienast J, et al. Efficacy and safety of thalidomide in patients with acute myeloid leukemia. Blood 2002; 99: 834-839.
-
(2002)
Blood
, vol.99
, pp. 834-839
-
-
Steins, M.B.1
Padro, T.2
Bieker, R.3
Ruiz, S.4
Kropff, M.5
Kienast, J.6
-
166
-
-
19944433802
-
Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias
-
Faderl S, Gandhi V, O'Brien S, Bonate P, Cortes J, Estey E, et al. Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias. Blood 2005; 105: 940-947.
-
(2005)
Blood
, vol.105
, pp. 940-947
-
-
Faderl, S.1
Gandhi, V.2
O'Brien, S.3
Bonate, P.4
Cortes, J.5
Estey, E.6
-
167
-
-
34548533162
-
Phase I/II study of continuous-infusion troxacitabine in refractory acute myeloid leukemia
-
Roboz GJ, Giles FJ, Ritchie EK, Len-Bard S, Curcio TJ, Wilkes MA, et al. Phase I/II study of continuous-infusion troxacitabine in refractory acute myeloid leukemia. J Clin Oncol 2007; 25: 10-15.
-
(2007)
J Clin Oncol
, vol.25
, pp. 10-15
-
-
Roboz, G.J.1
Giles, F.J.2
Ritchie, E.K.3
Len-Bard, S.4
Curcio, T.J.5
Wilkes, M.A.6
-
168
-
-
77953252405
-
Targeting the oncogene eIF4E with ribavirin: A novel therapeutic avenue in acute myeloid leukemia
-
Assouline S, Cocolakis E, Rousseau C, Culjkovic B, Beslu N, Amri A, et al. Targeting the oncogene eIF4E with ribavirin: a novel therapeutic avenue in acute myeloid leukemia. ASH Annual Meeting Abstracts 2009; 114: 2085.
-
(2009)
ASH Annual Meeting Abstracts
, vol.114
, pp. 2085
-
-
Assouline, S.1
Cocolakis, E.2
Rousseau, C.3
Culjkovic, B.4
Beslu, N.5
Amri, A.6
-
169
-
-
79952207806
-
Phase I/II study to assess the safety and efficacy of the aurora B kinase inhibitor, AZD1152, in patients with advanced acute myeloid leukemia
-
Lowenberg B, Rousselot P, Martinelli G, Goudie A, Stockman P, Kantarjian H. Phase I/II study to assess the safety and efficacy of the aurora B kinase inhibitor, AZD1152, in patients with advanced acute myeloid leukemia. ASH Annual Meeting Abstracts 2009; 114: 2080.
-
(2009)
ASH Annual Meeting Abstracts
, vol.114
, pp. 2080
-
-
Lowenberg, B.1
Rousselot, P.2
Martinelli, G.3
Goudie, A.4
Stockman, P.5
Kantarjian, H.6
-
170
-
-
70449475104
-
AML at older age: Age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance
-
de Jonge HJ, de Bont ES, Valk PJ, Schuringa JJ, Kies M, Woolthuis CM, et al. AML at older age: age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance. Blood 2009; 114: 2869-2877.
-
(2009)
Blood
, vol.114
, pp. 2869-2877
-
-
de Jonge, H.J.1
de Bont, E.S.2
Valk, P.J.3
Schuringa, J.J.4
Kies, M.5
Woolthuis, C.M.6
|